Selective endothelin A receptor ligands. 1. Discovery and structure-activity of 2,4-disubstituted benzoic acid derivatives

European Journal of Medicinal Chemistry

Volumn 32, Issue 5, 1997, Pages 409-423

  Astles, P C ^a   Brown, T J ^a   Handscombe, C M ^a   Harper, M F ^a   Harris, N V ^a   Lewis, R A ^a   Lockey, P M ^a   McCarthy, C ^a   McLay, I M ^a   Porter, B ^a   Roach, A G ^a   Smith, C ^a   Walsh, R J A ^a  

^a SANOFI   (France)

Author keywords

Benzoic acid; Endothelin receptor ligand

Indexed keywords

BENZOIC ACID DERIVATIVE; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONFORMATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

EID: 0030915571     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(97)81678-9     Document Type: Article

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