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Volumn 10, Issue 5, 1996, Pages 397-416
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Active-site-directed 3D database searching: Pharmacophore extraction and validation of hits
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Author keywords
Drug design; Lead generation; Scoring function; Thrombin inhibitors
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Indexed keywords
DATABASE SYSTEMS;
ENZYMES;
FREE ENERGY;
LEAD COMPOUNDS;
PHARMACODYNAMICS;
SYNTHESIS (CHEMICAL);
3D DATABASE;
ACTIVE SITE;
COMPUTATIONAL TOOLS;
DATABASE SEARCHING;
DRUG DESIGN;
FREE ENERGY OF BINDING;
LEAD GENERATION;
PHARMACOPHORES;
SCORING FUNCTIONS;
THROMBIN INHIBITORS;
EXTRACTION;
ARTICLE;
BINDING SITE;
CHEMICAL STRUCTURE;
COMPUTER AIDED DESIGN;
COMPUTER GRAPHICS;
COMPUTER PROGRAM;
COMPUTER SIMULATION;
DRUG DESIGN;
FACTUAL DATABASE;
MACROMOLECULE;
BINDING SITES;
COMPUTER GRAPHICS;
COMPUTER SIMULATION;
COMPUTER-AIDED DESIGN;
DATABASES, FACTUAL;
DRUG DESIGN;
MACROMOLECULAR SUBSTANCES;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
SOFTWARE;
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EID: 0030253210
PISSN: 0920654X
EISSN: None
Source Type: Journal
DOI: 10.1007/BF00124472 Document Type: Article |
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Times cited : (28)
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References (1)
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