Identification of novel farnesyl protein transferase inhibitors using three-dimensional database searching methods

Journal of Medicinal Chemistry

Volumn 40, Issue 25, 1997, Pages 4103-4112

  Kaminski, James J ^a   Rane, D F ^a   Snow, Mark E ^a   Weber, Lois ^a   Rothofsky, Marnie L ^a   Anderson, Samantha D ^a   Lin, Stanley L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (8 CHLORO 5,6 DIHYDRO 11H BENZO[5,6]CYCLOHEPTA[1,2 B]PYRIDIN 11 YLIDENE) 1 (4 PYRIDYLACETYL)PIPERIDINE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER PROGRAM; DATA BASE; DRUG CONFORMATION; DRUG SCREENING; DRUG STRUCTURE; STRUCTURE ACTIVITY RELATION;

ALKYL AND ARYL TRANSFERASES; DATABASES; ENZYME INHIBITORS; MODELS, STRUCTURAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031442297     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970291v     Document Type: Article

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