Properties of cytochrome P450 isoenzymes and their substrates Part 1: Active site characteristics

Drug Discovery Today

Volumn 2, Issue 10, 1997, Pages 406-414

  Smith, Dennis A ^a   Ackland, Mark J ^a   Jones, Barry C ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETANILIDE; AFLATOXIN B; ANESTHETIC AGENT; ANTIINFECTIVE AGENT; CAFFEINE; CAMPHOR; COUMARIN; CYCLOSPORIN A; CYTOCHROME P450 ISOENZYME; GESTODENE; GRANISETRON; KETOCONAZOLE; MACROLIDE; MEPHENYTOIN; NIFEDIPINE; OMEPRAZOLE; ONDANSETRON; PARACETAMOL; PENTOXYRESORUFIN; PHENACETIN; PHENOL DERIVATIVE; PHENYTOIN; SALMETEROL; STEROID; TAMOXIFEN; TIENILIC ACID; TOLBUTAMIDE; UNINDEXED DRUG; XANTHINE DERIVATIVE; ZOXAZOLAMINE;

BINDING SITE; CRYSTAL STRUCTURE; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; HUMAN; REVIEW; STEREOSPECIFICITY; XENOBIOTIC METABOLISM;

EID: 0030924503     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(97)01081-7     Document Type: Article

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