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Volumn 38, Issue , 2018, Pages 69-96

Bioavailability of fat-soluble vitamins and phytochemicals in humans: Effects of genetic variation

Author keywords

absorption; carotenoids; lutein; lycopene; phytosterols; polymorphisms

Indexed keywords

ALPHA TOCOPHEROL; BETA CAROTENE; LYCOPENE; PHYTOCHEMICAL; PHYTOSTEROL; VITAMIN; VITAMIN D; XANTHOPHYLL;

EID: 85052210479     PISSN: 01999885     EISSN: 15454312     Source Type: Book Series    
DOI: 10.1146/annurev-nutr-082117-051628     Document Type: Review
Times cited : (74)

References (147)
  • 1
    • 84864062804 scopus 로고    scopus 로고
    • Role of the gut in lipid homeostasis
    • Abumrad NA, Davidson NO. 2012. Role of the gut in lipid homeostasis. Physiol. Rev. 92:1061-85
    • (2012) Physiol. Rev. , vol.92 , pp. 1061-1085
    • Abumrad, N.A.1    Davidson, N.O.2
  • 2
    • 84911429837 scopus 로고    scopus 로고
    • Genetically low Vitamin D concentrations and increased mortality: Mendelian randomisation analysis in three large cohorts
    • Afzal S, Brondum-Jacobsen P, Bojesen SE, Nordestgaard BG. 2014. Genetically low Vitamin D concentrations and increased mortality: Mendelian randomisation analysis in three large cohorts. BMJ 349:g6330
    • (2014) BMJ , vol.349 , pp. g6330
    • Afzal, S.1    Brondum-Jacobsen, P.2    Bojesen, S.E.3    Nordestgaard, B.G.4
  • 3
    • 33846173940 scopus 로고    scopus 로고
    • Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein
    • AlrefaiWA, Annaba F, Sarwar Z,Dwivedi A, Saksena S, et al. 2007. Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: role of sterol regulatory element binding protein. Am. J. Physiol. Gastrointest. Liver Physiol. 292:G369-76
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.292 , pp. G369-G376
    • Alrefai, W.A.1    Annaba, F.2    Sarwar, Z.3    Dwivedi, A.4    Saksena, S.5
  • 4
    • 10744221008 scopus 로고    scopus 로고
    • Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption
    • Altmann SW, Davis HR Jr., Zhu LJ, Yao X, Hoos LM, et al. 2004. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science 303:1201-4
    • (2004) Science , vol.303 , pp. 1201-1204
    • Altmann, S.W.1    Davis, H.R.2    Zhu, L.J.3    Yao, X.4    Hoos, L.M.5
  • 5
    • 84898484202 scopus 로고    scopus 로고
    • Age-related Eye Disease Study 2: Perspectives, recommendations, and unanswered questions
    • Aronow ME, Chew EY. 2014. Age-related Eye Disease Study 2: perspectives, recommendations, and unanswered questions. Curr. Opin. Ophthalmol. 25:186-90
    • (2014) Curr. Opin. Ophthalmol. , vol.25 , pp. 186-190
    • Aronow, M.E.1    Chew, E.Y.2
  • 6
    • 84899725600 scopus 로고    scopus 로고
    • Genetic polymorphism of cytochrome P450 4F2, Vitamin E level and histological response in adults and children with nonalcoholic fatty liver disease who participated in PIVENS and TONIC clinical trials
    • Athinarayanan S,Wei R, ZhangM, Bai S, Traber MG, et al. 2014. Genetic polymorphism of cytochrome P450 4F2, Vitamin E level and histological response in adults and children with nonalcoholic fatty liver disease who participated in PIVENS and TONIC clinical trials. PLOS ONE 9:e95366
    • (2014) PLOS ONE , vol.9 , pp. e95366
    • Athinarayanan, S.1    Wei, R.2    Zhang, M.3    Bai, S.4    Traber, M.G.5
  • 7
    • 84876435852 scopus 로고    scopus 로고
    • Lycopene-derived bioactive retinoic acid receptors/retinoid-X receptors-activating metabolites may be relevant for lycopene's anti-cancer potential
    • Aydemir G, Kasiri Y, Birta E, Beke G, Garcia AL, et al. 2013. Lycopene-derived bioactive retinoic acid receptors/retinoid-X receptors-activating metabolites may be relevant for lycopene's anti-cancer potential. Mol. Nutr. Food Res. 57:739-47
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 739-747
    • Aydemir, G.1    Kasiri, Y.2    Birta, E.3    Beke, G.4    Garcia, A.L.5
  • 8
    • 77949771168 scopus 로고    scopus 로고
    • Estimation of total usual calcium and Vitamin D intakes in the United States
    • Bailey RL, Dodd KW, Goldman JA, Gahche JJ, Dwyer JT, et al. 2010. Estimation of total usual calcium and Vitamin D intakes in the United States. J. Nutr. 140:817-22
    • (2010) J. Nutr. , vol.140 , pp. 817-822
    • Bailey, R.L.1    Dodd, K.W.2    Goldman, J.A.3    Gahche, J.J.4    Dwyer, J.T.5
  • 9
    • 84907654800 scopus 로고    scopus 로고
    • Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of Vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial
    • Barry EL, Rees JR, Peacock JL, Mott LA, Amos CI, et al. 2014. Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of Vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial. J. Clin. Endocrinol. Metab. 99:E2133-37
    • (2014) J. Clin. Endocrinol. Metab. , vol.99 , pp. E2133-E2137
    • Barry, E.L.1    Rees, J.R.2    Peacock, J.L.3    Mott, L.A.4    Amos, C.I.5
  • 10
    • 17744390348 scopus 로고    scopus 로고
    • Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
    • Berge KE, Tian H, Graf GA, Yu L, Grishin NV, et al. 2000. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290:1771-75
    • (2000) Science , vol.290 , pp. 1771-1775
    • Berge, K.E.1    Tian, H.2    Graf, G.A.3    Yu, L.4    Grishin, N.V.5
  • 11
    • 0036203457 scopus 로고    scopus 로고
    • Heritability of plasma noncholesterol sterols and relationship toDNA sequence polymorphism in ABCG5 and ABCG8
    • Berge KE, von Bergmann K, Lutjohann D, Guerra R, Grundy SM, et al. 2002. Heritability of plasma noncholesterol sterols and relationship toDNA sequence polymorphism in ABCG5 and ABCG8. J. Lipid Res. 43:486-94
    • (2002) J. Lipid Res. , vol.43 , pp. 486-494
    • Berge, K.E.1    Von Bergmann, K.2    Lutjohann, D.3    Guerra, R.4    Grundy, S.M.5
  • 12
    • 84955419184 scopus 로고    scopus 로고
    • Lutein, zeaxanthin, and mesozeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease
    • Bernstein PS, Li B, Vachali PP, Gorusupudi A, Shyam R, et al. 2016. Lutein, zeaxanthin, and mesozeaxanthin: the basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. Prog. Retin. Eye Res. 50:34-66
    • (2016) Prog. Retin. Eye Res. , vol.50 , pp. 34-66
    • Bernstein, P.S.1    Li, B.2    Vachali, P.P.3    Gorusupudi, A.4    Shyam, R.5
  • 14
    • 77951529201 scopus 로고    scopus 로고
    • Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype
    • Blum S, Vardi M, Brown JB, Russell A, Milman U, et al. 2010. Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype. Pharmacogenomics 11:675-84
    • (2010) Pharmacogenomics , vol.11 , pp. 675-684
    • Blum, S.1    Vardi, M.2    Brown, J.B.3    Russell, A.4    Milman, U.5
  • 15
    • 85013862057 scopus 로고    scopus 로고
    • Host-related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans
    • Bohn T, Desmarchelier C,Dragsted LO, Nielsen CS, StahlW, et al. 2017. Host-related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans. Mol. Nutr. Food Res. 61:201600685
    • (2017) Mol. Nutr. Food Res. , vol.61 , pp. 201600685
    • Bohn, T.1    Desmarchelier, C.2    Dragsted, L.O.3    Nielsen, C.S.4    Stahl, W.5
  • 16
    • 0042354087 scopus 로고    scopus 로고
    • Factors affecting intestinal absorption of highly lipophilic food microconstituents (fatsoluble vitamins, carotenoids and phytosterols)
    • Borel P. 2003. Factors affecting intestinal absorption of highly lipophilic food microconstituents (fatsoluble vitamins, carotenoids and phytosterols). Clin. Chem. Lab. Med. 41:979-94
    • (2003) Clin. Chem. Lab. Med. , vol.41 , pp. 979-994
    • Borel, P.1
  • 17
    • 84858320870 scopus 로고    scopus 로고
    • Genetic variations involved in interindividual variability in carotenoid status
    • Borel P. 2012. Genetic variations involved in interindividual variability in carotenoid status. Mol. Nutr. Food Res. 56:228-40
    • (2012) Mol. Nutr. Food Res. , vol.56 , pp. 228-240
    • Borel, P.1
  • 18
    • 78651387052 scopus 로고    scopus 로고
    • Genetic variants in BCMO1 and CD36 are associated with plasma lutein concentrations and macular pigment optical density in humans
    • Borel P, de Edelenyi FS, Vincent-Baudry S, Malezet-Desmoulin C, Margotat A, et al. 2010. Genetic variants in BCMO1 and CD36 are associated with plasma lutein concentrations and macular pigment optical density in humans. Ann. Med. 43:47-59
    • (2010) Ann. Med. , vol.43 , pp. 47-59
    • Borel, P.1    De Edelenyi, F.S.2    Vincent-Baudry, S.3    Malezet-Desmoulin, C.4    Margotat, A.5
  • 19
    • 85006789594 scopus 로고    scopus 로고
    • Genetic variations involved in Vitamin E status
    • Borel P, Desmarchelier C. 2016. Genetic variations involved in Vitamin E status. Int. J. Mol. Sci. 17:2094
    • (2016) Int. J. Mol. Sci. , vol.17 , pp. 2094
    • Borel, P.1    Desmarchelier, C.2
  • 20
    • 85014898373 scopus 로고    scopus 로고
    • Genetic variations associated with Vitamin A status and Vitamin A bioavailability
    • Borel P, Desmarchelier C. 2017. Genetic variations associated with Vitamin A status and Vitamin A bioavailability. Nutrients 9:246
    • (2017) Nutrients , vol.9 , pp. 246
    • Borel, P.1    Desmarchelier, C.2
  • 21
    • 84938929230 scopus 로고    scopus 로고
    • A combination of single-nucleotide polymorphisms is associated with interindividual variability in dietary β-carotene bioavailability in healthy men
    • Borel P,DesmarchelierC,NowickiM, Bott R. 2015. A combination of single-nucleotide polymorphisms is associated with interindividual variability in dietary β-carotene bioavailability in healthy men. J. Nutr. 145:1740-47
    • (2015) J. Nutr. , vol.145 , pp. 1740-1747
    • Borel, P.1    Desmarchelier, C.2    Nowicki, M.3    Bott, R.4
  • 22
    • 84928387996 scopus 로고    scopus 로고
    • Lycopene bioavailability is associated with a combination of genetic variants
    • Borel P, Desmarchelier C, Nowicki M, Bott R. 2015. Lycopene bioavailability is associated with a combination of genetic variants. Free Radic. Biol. Med. 83:238-44
    • (2015) Free Radic. Biol. Med. , vol.83 , pp. 238-244
    • Borel, P.1    Desmarchelier, C.2    Nowicki, M.3    Bott, R.4
  • 23
    • 84903527424 scopus 로고    scopus 로고
    • Interindividual variability of lutein bioavailability in healthy men: Characterization, genetic variants involved, and relation with fasting plasma lutein concentration
    • Borel P, Desmarchelier C, Nowicki M, Bott R, Morange S, Lesavre N. 2014. Interindividual variability of lutein bioavailability in healthy men: characterization, genetic variants involved, and relation with fasting plasma lutein concentration. Am. J. Clin. Nutr. 100:168-75
    • (2014) Am. J. Clin. Nutr. , vol.100 , pp. 168-175
    • Borel, P.1    Desmarchelier, C.2    Nowicki, M.3    Bott, R.4    Morange, S.5    Lesavre, N.6
  • 24
    • 84923933142 scopus 로고    scopus 로고
    • Can genetic variability in α-tocopherol bioavailability explain the heterogeneous response to α-tocopherol supplements?
    • Borel P, Desmarchelier C, Nowicki M, Bott R, Tourniaire F. 2015. Can genetic variability in α-tocopherol bioavailability explain the heterogeneous response to α-tocopherol supplements? Antioxid. Redox Signal. 22:669-78
    • (2015) Antioxid. Redox Signal. , vol.22 , pp. 669-678
    • Borel, P.1    Desmarchelier, C.2    Nowicki, M.3    Bott, R.4    Tourniaire, F.5
  • 25
    • 0031755369 scopus 로고    scopus 로고
    • Low and high responders to pharmacological doses of β-carotene: Proportion in the population, mechanisms involved and consequences on β-carotene metabolism
    • Borel P, Grolier P, Mekki N, Boirie Y, Rochette Y, et al. 1998. Low and high responders to pharmacological doses of β-carotene: proportion in the population, mechanisms involved and consequences on β-carotene metabolism. J. Lipid Res. 39:2250-60
    • (1998) J. Lipid Res. , vol.39 , pp. 2250-2260
    • Borel, P.1    Grolier, P.2    Mekki, N.3    Boirie, Y.4    Rochette, Y.5
  • 26
    • 0028470598 scopus 로고
    • Vitamin E: Molecular and biological function
    • Burton GW. 1994. Vitamin E: molecular and biological function. Proc. Nutr. Soc. 53:251-62
    • (1994) Proc. Nutr. Soc. , vol.53 , pp. 251-262
    • Burton, G.W.1
  • 27
    • 0037119447 scopus 로고    scopus 로고
    • Human calcium-sensing receptor gene: Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D
    • Canaff L, Hendy GN. 2002. Human calcium-sensing receptor gene: Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D. J. Biol. Chem. 277:30337-50
    • (2002) J. Biol. Chem. , vol.277 , pp. 30337-30350
    • Canaff, L.1    Hendy, G.N.2
  • 28
    • 84884704107 scopus 로고    scopus 로고
    • Vitamin E: A dark horse at the crossroad of cancer management
    • Cardenas E, Ghosh R. 2013. Vitamin E: a dark horse at the crossroad of cancer management. Biochem. Pharmacol. 86:845-52
    • (2013) Biochem. Pharmacol. , vol.86 , pp. 845-852
    • Cardenas, E.1    Ghosh, R.2
  • 29
    • 84880809412 scopus 로고    scopus 로고
    • Primary Vitamin D target genes allow a categorization of possible benefits of Vitamin D3 supplementation
    • Carlberg C, Seuter S, de Mello VD, Schwab U, Voutilainen S, et al. 2013. Primary Vitamin D target genes allow a categorization of possible benefits of Vitamin D3 supplementation. PLOS ONE 8:e71042
    • (2013) PLOS ONE , vol.8 , pp. e71042
    • Carlberg, C.1    Seuter, S.2    De Mello, V.D.3    Schwab, U.4    Voutilainen, S.5
  • 31
    • 84880777927 scopus 로고    scopus 로고
    • Lycopene/tomato consumption and the risk of prostate cancer: A systematic review and meta-analysis of prospective studies
    • Chen J, Song Y, Zhang L. 2013. Lycopene/tomato consumption and the risk of prostate cancer: a systematic review and meta-analysis of prospective studies. J. Nutr. Sci. Vitaminol. 59:213-23
    • (2013) J. Nutr. Sci. Vitaminol. , vol.59 , pp. 213-223
    • Chen, J.1    Song, Y.2    Zhang, L.3
  • 32
    • 85010302942 scopus 로고    scopus 로고
    • Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis
    • ChengHM, KoutsidisG, Lodge JK, Ashor A, Siervo M, Lara J. 2017. Tomato and lycopene supplementation and cardiovascular risk factors: a systematic review and meta-analysis. Atherosclerosis 257:100-8
    • (2017) Atherosclerosis , vol.257 , pp. 100-108
    • Cheng, H.M.1    Koutsidis, G.2    Lodge, J.K.3    Ashor, A.4    Siervo, M.5    Lara, J.6
  • 34
    • 32444441330 scopus 로고    scopus 로고
    • Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels
    • Cohen JC, Pertsemlidis A, Fahmi S, Esmail S, Vega GL, et al. 2006. Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. PNAS 103:1810-15
    • (2006) PNAS , vol.103 , pp. 1810-1815
    • Cohen, J.C.1    Pertsemlidis, A.2    Fahmi, S.3    Esmail, S.4    Vega, G.L.5
  • 36
    • 4043124013 scopus 로고    scopus 로고
    • Niemann-PickC1Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis
    • DavisHRJr.,Zhu LJ, Hoos LM,Tetzloff G, MaguireM, et al. 2004. Niemann-PickC1Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. J. Biol. Chem. 279:33586-92
    • (2004) J. Biol. Chem. , vol.279 , pp. 33586-33592
    • Davis, H.R.1    Zhu, L.J.2    Hoos, L.M.3    Tetzloff, G.4    Maguire, M.5
  • 38
    • 0029809828 scopus 로고    scopus 로고
    • Dietary carotenoids and their role in combating Vitamin A deficiency: A review of the literature
    • de Pee S,West CE. 1996. Dietary carotenoids and their role in combating Vitamin A deficiency: a review of the literature. Eur. J. Clin. Nutr. 50(Suppl. 3):S38-53
    • (1996) Eur. J. Clin. Nutr. , vol.50 , Issue.3 , pp. S38-53
    • De Pee, S.1    West, C.E.2
  • 39
    • 85018704994 scopus 로고    scopus 로고
    • Overview of carotenoid bioavailability determinants: From dietary factors to host genetic variations
    • Desmarchelier C, Borel P. 2017. Overview of carotenoid bioavailability determinants: from dietary factors to host genetic variations. Trends Food Sci. Technol. 69:270-80
    • (2017) Trends Food Sci. Technol. , vol.69 , pp. 270-280
    • Desmarchelier, C.1    Borel, P.2
  • 40
    • 85006963789 scopus 로고    scopus 로고
    • A combination of singlenucleotide polymorphisms is associated with interindividual variability in cholecalciferol bioavailability in healthy men
    • Desmarchelier C, Borel P, Goncalves A, Kopec R, Nowicki M, et al. 2016. A combination of singlenucleotide polymorphisms is associated with interindividual variability in cholecalciferol bioavailability in healthy men. J. Nutr. 146:2421-28
    • (2016) J. Nutr. , vol.146 , pp. 2421-2428
    • Desmarchelier, C.1    Borel, P.2    Goncalves, A.3    Kopec, R.4    Nowicki, M.5
  • 41
    • 85032264846 scopus 로고    scopus 로고
    • Comparison of the micellar incorporation and the intestinal cell uptake of cholecalciferol, 25-hydroxycholecalciferol and 1-α-hydroxycholecalciferol
    • Desmarchelier C, Margier M, Preveraud D, Nowicki M, Rosilio V, et al. 2017. Comparison of the micellar incorporation and the intestinal cell uptake of cholecalciferol, 25-hydroxycholecalciferol and 1-α-hydroxycholecalciferol. Nutrients 9:1152
    • (2017) Nutrients , vol.9 , pp. 1152
    • Desmarchelier, C.1    Margier, M.2    Preveraud, D.3    Nowicki, M.4    Rosilio, V.5
  • 42
    • 84895811341 scopus 로고    scopus 로고
    • The postprandial chylomicron triacylglycerol response to dietary fat in healthy Male adults is significantly explained by a combination of single nucleotide polymorphisms in genes involved in triacylglycerol metabolism
    • Desmarchelier C, Martin JC, Planells R, Gastaldi M, Nowicki M, et al. 2014. The postprandial chylomicron triacylglycerol response to dietary fat in healthy male adults is significantly explained by a combination of single nucleotide polymorphisms in genes involved in triacylglycerol metabolism. J. Clin. Endocrinol. Metab. 99:E484-88
    • (2014) J. Clin. Endocrinol. Metab. , vol.99 , pp. E484-E488
    • Desmarchelier, C.1    Martin, J.C.2    Planells, R.3    Gastaldi, M.4    Nowicki, M.5
  • 43
    • 84885147841 scopus 로고    scopus 로고
    • The serum 25-hydroxyvitaminDresponse to vitaminDsupplementation is related to genetic factors, BMI, and baseline levels
    • Didriksen A, Grimnes G, Hutchinson MS, Kjaergaard M, Svartberg J, et al. 2013. The serum 25-hydroxyvitaminDresponse to vitaminDsupplementation is related to genetic factors, BMI, and baseline levels. Eur. J. Endocrinol. 169:559-67
    • (2013) Eur. J. Endocrinol. , vol.169 , pp. 559-567
    • Didriksen, A.1    Grimnes, G.2    Hutchinson, M.S.3    Kjaergaard, M.4    Svartberg, J.5
  • 44
    • 68049097903 scopus 로고    scopus 로고
    • Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium
    • Duncan KG, Hosseini K, Bailey KR, Yang H, Lowe RJ, et al. 2009. Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium. Br. J. Ophthalmol. 93:1116-20
    • (2009) Br. J. Ophthalmol. , vol.93 , pp. 1116-1120
    • Duncan, K.G.1    Hosseini, K.2    Bailey, K.R.3    Yang, H.4    Lowe, R.J.5
  • 45
    • 26444537961 scopus 로고    scopus 로고
    • Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe
    • During A, Dawson HD, Harrison EH. 2005. Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe. J. Nutr. 135:2305-12
    • (2005) J. Nutr. , vol.135 , pp. 2305-2312
    • During, A.1    Dawson, H.D.2    Harrison, E.H.3
  • 46
    • 46249103255 scopus 로고    scopus 로고
    • Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes
    • Fahmi S, Yang C, Esmail S, Hobbs HH, Cohen JC. 2008. Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes. Hum. Mol. Genet. 17:2101-7
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 2101-2107
    • Fahmi, S.1    Yang, C.2    Esmail, S.3    Hobbs, H.H.4    Cohen, J.C.5
  • 48
    • 85017592723 scopus 로고    scopus 로고
    • Lycopene and tomato powder supplementation similarly inhibit high-fat diet induced obesity, inflammatory response and associated metabolic disorders
    • In press.
    • Fenni S, Hammou H, Astier J, Bonnet L, Karkeni E, et al. 2017. Lycopene and tomato powder supplementation similarly inhibit high-fat diet induced obesity, inflammatory response and associated metabolic disorders. Mol. Nutr. Food Res. In press. https://doi.org/10.1002/mnfr.201601083
    • (2017) Mol. Nutr. Food Res
    • Fenni, S.1    Hammou, H.2    Astier, J.3    Bonnet, L.4    Karkeni, E.5
  • 49
    • 62649145645 scopus 로고    scopus 로고
    • Common variation in the β-carotene 15,15-monooxygenase 1 gene affects circulating levels of carotenoids: A genome-wide association study
    • Ferrucci L, Perry JR,Matteini A, PerolaM, Tanaka T, et al. 2009. Common variation in the β-carotene 15,15-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study. Am. J. Hum. Genet. 84:123-33
    • (2009) Am. J. Hum. Genet. , vol.84 , pp. 123-133
    • Ferrucci, L.1    Perry, J.R.2    Matteini, A.3    Perola, M.4    Tanaka, T.5
  • 50
    • 84859597301 scopus 로고    scopus 로고
    • Vitamin E decreases bonemass by stimulating osteoclast fusion
    • Fujita K, IwasakiM,OchiH, Fukuda T, Ma C, et al. 2012. Vitamin E decreases bonemass by stimulating osteoclast fusion. Nat. Med. 18:589-94
    • (2012) Nat. Med. , vol.18 , pp. 589-594
    • Fujita, K.1    Iwasaki, M.2    Ochi, H.3    Fukuda, T.4    Ma, C.5
  • 52
    • 84879689001 scopus 로고    scopus 로고
    • Do we know enough? A scientific and ethical analysis of the basis for genetic-based personalized nutrition
    • Gorman U, Mathers JC, Grimaldi KA, Ahlgren J,Nordstrom K. 2013. Do we know enough? A scientific and ethical analysis of the basis for genetic-based personalized nutrition. Genes Nutr. 8:373-81
    • (2013) Genes Nutr. , vol.8 , pp. 373-381
    • Gorman, U.1    Mathers, J.C.2    Grimaldi, K.A.3    Ahlgren, J.4    Nordstrom, K.5
  • 56
    • 4644279032 scopus 로고    scopus 로고
    • Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity
    • Gylling H, Hallikainen M, Pihlajamaki J, Agren J, Laakso M, et al. 2004. Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity. J. Lipid Res. 45:1660-65
    • (2004) J. Lipid Res. , vol.45 , pp. 1660-1665
    • Gylling, H.1    Hallikainen, M.2    Pihlajamaki, J.3    Agren, J.4    Laakso, M.5
  • 58
    • 84867797696 scopus 로고    scopus 로고
    • The challenge to reach nutritional adequacy for Vitamin A: β-carotene bioavailability and conversion-evidence in humans
    • HaskellMJ. 2012. The challenge to reach nutritional adequacy for Vitamin A: β-carotene bioavailability and conversion-evidence in humans. Am. J. Clin. Nutr. 96:1193S-203S
    • (2012) Am. J. Clin. Nutr. , vol.96 , pp. 1193S-1203S
    • Haskell, M.J.1
  • 59
    • 84869805512 scopus 로고    scopus 로고
    • β-carotene 15,15-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent
    • Hendrickson SJ, Hazra A, Chen C, Eliassen AH, Kraft P, et al. 2012. β-carotene 15,15-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent. Am. J. Clin. Nutr. 96:1379-89
    • (2012) Am. J. Clin. Nutr. , vol.96 , pp. 1379-1389
    • Hendrickson, S.J.1    Hazra, A.2    Chen, C.3    Eliassen, A.H.4    Kraft, P.5
  • 60
    • 84864583282 scopus 로고    scopus 로고
    • Top food sources contributing to vitaminDintake and the association of ready-to-eat cereal and breakfast consumption habits to Vitamin D intake in Canadians and United States Americans
    • Hill KM, Jonnalagadda SS, Albertson AM, JoshiNA, Weaver CM. 2012. Top food sources contributing to vitaminDintake and the association of ready-to-eat cereal and breakfast consumption habits to Vitamin D intake in Canadians and United States Americans. J. Food Sci. 77:H170-75
    • (2012) J. Food Sci. , vol.77 , pp. H170-H175
    • Hill, K.M.1    Jonnalagadda, S.S.2    Albertson, A.M.3    Joshi, N.A.4    Weaver, C.M.5
  • 63
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, BrownMS. 2002. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Investig. 109:1125-31
    • (2002) J. Clin. Investig. , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 64
    • 4143073559 scopus 로고    scopus 로고
    • Polymorphisms in ABCG5 and ABCG8 transporters and plasma cholesterol levels
    • Hubacek JA, Berge KE, Stefkova J, Pitha J, Skodova Z, et al. 2004. Polymorphisms in ABCG5 and ABCG8 transporters and plasma cholesterol levels. Physiol. Res. 53:395-401
    • (2004) Physiol. Res. , vol.53 , pp. 395-401
    • Hubacek, J.A.1    Berge, K.E.2    Stefkova, J.3    Pitha, J.4    Skodova, Z.5
  • 65
    • 27944440390 scopus 로고    scopus 로고
    • Dietary reference intakes for Vitamin C, Vitamin E, selenium, and carotenoids
    • Washington, DC: Natl. Acad.
    • Inst. Med. Panel Diet. Antioxid. Relate. Compd. 2000. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids.Washington, DC: Natl. Acad.
    • (2000) Inst. Med. Panel Diet. Antioxid. Relate. Compd
  • 66
    • 79959503826 scopus 로고    scopus 로고
    • The international hapmap project
    • Int. HapMap Consort
    • Int. HapMap Consort. 2003. The International HapMap Project. Nature 426:789-96
    • (2003) Nature , vol.426 , pp. 789-796
  • 67
    • 77956331627 scopus 로고    scopus 로고
    • Integrating common and rare genetic variation in diverse human populations
    • Int. HapMap3 Consort
    • Int. HapMap3 Consort. 2010. Integrating common and rare genetic variation in diverse human populations. Nature 467:52-58
    • (2010) Nature , vol.467 , pp. 52-58
  • 69
    • 77956848690 scopus 로고    scopus 로고
    • ABCG5/G8 polymorphisms and markers of cholesterol metabolism: Systematic review and meta-analysis
    • Jakulj L, Vissers MN, Tanck MW, Hutten BA, Stellaard F, et al. 2010. ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis. J. Lipid Res. 51:3016-23
    • (2010) J. Lipid Res. , vol.51 , pp. 3016-3023
    • Jakulj, L.1    Vissers, M.N.2    Tanck, M.W.3    Hutten, B.A.4    Stellaard, F.5
  • 70
    • 0035185941 scopus 로고    scopus 로고
    • γ-Tocopherol, the major form of Vitamin E in the US diet, deserves more attention
    • Jiang Q, Christen S, Shigenaga MK, Ames BN. 2001. γ-Tocopherol, the major form of Vitamin E in the US diet, deserves more attention. Am. J. Clin. Nutr. 74:714-22
    • (2001) Am. J. Clin. Nutr. , vol.74 , pp. 714-722
    • Jiang, Q.1    Christen, S.2    Shigenaga, M.K.3    Ames, B.N.4
  • 71
    • 11144239577 scopus 로고    scopus 로고
    • γ-Tocopherol or combinations of Vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis
    • Jiang Q, Wong J, Fyrst H, Saba JD, Ames BN. 2004. γ-Tocopherol or combinations of Vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. PNAS 101:17825-30
    • (2004) PNAS , vol.101 , pp. 17825-17830
    • Jiang, Q.1    Wong, J.2    Fyrst, H.3    Saba, J.D.4    Ames, B.N.5
  • 72
    • 85047698220 scopus 로고    scopus 로고
    • Safety, health, and methodological aspects of plant sterols and stanols
    • Jones P, MacKay D. 2015. Safety, health, and methodological aspects of plant sterols and stanols. J. AOAC Int. 98:671-73
    • (2015) J. AOAC Int. , vol.98 , pp. 671-673
    • Jones, P.1    MacKay, D.2
  • 73
    • 34548071640 scopus 로고    scopus 로고
    • Functional variant ofmanganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study
    • KangD, Lee KM, Park SK, Berndt SI, PetersU, et al. 2007. Functional variant ofmanganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study. Cancer Epidemiol. Biomark. Prev. 16:1581-86
    • (2007) Cancer Epidemiol. Biomark. Prev. , vol.16 , pp. 1581-1586
    • Kang, D.1    Lee, K.M.2    Park, S.K.3    Berndt, S.I.4    Peters, U.5
  • 75
    • 0023393613 scopus 로고
    • Intestinal cholesterol absorption efficiency in man is related to apoprotein e phenotype
    • Kesaniemi YA, Ehnholm C, Miettinen TA. 1987. Intestinal cholesterol absorption efficiency in man is related to apoprotein E phenotype. J. Clin. Investig. 80:578-81
    • (1987) J. Clin. Investig. , vol.80 , pp. 578-581
    • Kesaniemi, Y.A.1    Ehnholm, C.2    Miettinen, T.A.3
  • 76
    • 0026655945 scopus 로고
    • Separation and identification of carotenoids and their oxidation products in the extracts of human plasma
    • Khachik F, Beecher GR, Goli MB, Lusby WR, Smith JC. 1992. Separation and identification of carotenoids and their oxidation products in the extracts of human plasma. Anal. Chem. 64:2111-22
    • (1992) Anal. Chem. , vol.64 , pp. 2111-2122
    • Khachik, F.1    Beecher, G.R.2    Goli, M.B.3    Lusby, W.R.4    Smith, J.C.5
  • 77
    • 71549135671 scopus 로고    scopus 로고
    • Adiponectin expression is induced by Vitamin E via a peroxisome proliferator-activated receptor γ-dependent mechanism
    • Landrier JF, Gouranton E, El Yazidi C, Malezet C, Balaguer P, et al. 2009. Adiponectin expression is induced by Vitamin E via a peroxisome proliferator-activated receptor γ-dependent mechanism. Endocrinology 150:5318-25
    • (2009) Endocrinology , vol.150 , pp. 5318-5325
    • Landrier, J.F.1    Gouranton, E.2    El Yazidi, C.3    Malezet, C.4    Balaguer, P.5
  • 79
    • 65349134706 scopus 로고    scopus 로고
    • Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15-monoxygenase alter β-carotene metabolism in female volunteers
    • Leung WC, Hessel S, Meplan C, Flint J, Oberhauser V, et al. 2009. Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15-monoxygenase alter β-carotene metabolism in female volunteers. FASEB J. 23:1041-53
    • (2009) FASEB J. , vol.23 , pp. 1041-1053
    • Leung, W.C.1    Hessel, S.2    Meplan, C.3    Flint, J.4    Oberhauser, V.5
  • 80
    • 84855524094 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms upstream from the β-carotene 15,15-monoxygenase gene influence provitamin A conversion efficiency in female volunteers
    • Lietz G, Oxley A, Leung W, Hesketh J. 2012. Single nucleotide polymorphisms upstream from the β-carotene 15,15-monoxygenase gene influence provitamin A conversion efficiency in female volunteers. J. Nutr. 142:161S-65S
    • (2012) J. Nutr. , vol.142 , pp. 161S-165S
    • Lietz, G.1    Oxley, A.2    Leung, W.3    Hesketh, J.4
  • 82
    • 84874109471 scopus 로고    scopus 로고
    • A silent mutation of Niemann-Pick C1-like 1 and apolipoprotein E4 modulate cholesterol absorption in primary hyperlipidemias
    • Lupattelli G, Pisciotta L, De Vuono S, Siepi D, Bellocchio A, et al. 2013. A silent mutation of Niemann-Pick C1-like 1 and apolipoprotein E4 modulate cholesterol absorption in primary hyperlipidemias. J. Clin. Lipidol. 7:147-52
    • (2013) J. Clin. Lipidol. , vol.7 , pp. 147-152
    • Lupattelli, G.1    Pisciotta, L.2    De Vuono, S.3    Siepi, D.4    Bellocchio, A.5
  • 84
    • 84862108559 scopus 로고    scopus 로고
    • Genome-wide association study identifies three common variants associated with serologic response to Vitamin E supplementation in men
    • Major JM, Yu K, Chung CC, Weinstein SJ, Yeager M, et al. 2012. Genome-wide association study identifies three common variants associated with serologic response to Vitamin E supplementation in men. J. Nutr. 142:866-71
    • (2012) J. Nutr. , vol.142 , pp. 866-871
    • Major, J.M.1    Yu, K.2    Chung, C.C.3    Weinstein, S.J.4    Yeager, M.5
  • 85
    • 84861692997 scopus 로고    scopus 로고
    • Lycopene attenuates LPS-induced TNF-α secretion in macrophages and inflammatory markers in adipocytes exposed to macrophage-conditioned media
    • Marcotorchino J, Romier B, Gouranton E, Riollet C, Gleize B, et al. 2012. Lycopene attenuates LPS-induced TNF-α secretion in macrophages and inflammatory markers in adipocytes exposed to macrophage-conditioned media. Mol. Nutr. Food Res. 56:725-32
    • (2012) Mol. Nutr. Food Res. , vol.56 , pp. 725-732
    • Marcotorchino, J.1    Romier, B.2    Gouranton, E.3    Riollet, C.4    Gleize, B.5
  • 86
    • 84979021832 scopus 로고    scopus 로고
    • Lutein and zeaxanthin isomers in eye health and disease
    • Mares J. 2016. Lutein and zeaxanthin isomers in eye health and disease. Annu. Rev. Nutr. 36:571-602
    • (2016) Annu. Rev. Nutr. , vol.36 , pp. 571-602
    • Mares, J.1
  • 87
    • 84877121987 scopus 로고    scopus 로고
    • VKORC1-dependent pharmacokinetics of intravenous and oral phylloquinone (vitamin K1) mixed micelles formulation
    • Marinova M, Lutjohann D, Breuer O, Kolsch H,Westhofen P, et al. 2013. VKORC1-dependent pharmacokinetics of intravenous and oral phylloquinone (vitamin K1) mixed micelles formulation. Eur. J. Clin. Pharmacol. 69:467-75
    • (2013) Eur. J. Clin. Pharmacol. , vol.69 , pp. 467-475
    • Marinova, M.1    Lutjohann, D.2    Breuer, O.3    Kolsch, H.4    Westhofen, P.5
  • 88
    • 84949604525 scopus 로고    scopus 로고
    • Eicosapentaenoic acid inhibits intestinal β-carotene absorption by downregulation of lipid transporter expression via PPAR-α dependent mechanism
    • Mashurabad PC, Kondaiah P, Palika R, Ghosh S, Nair MK, Raghu P. 2016. Eicosapentaenoic acid inhibits intestinal β-carotene absorption by downregulation of lipid transporter expression via PPAR-α dependent mechanism. Arch. Biochem. Biophys. 590:118-24
    • (2016) Arch. Biochem. Biophys. , vol.590 , pp. 118-124
    • Mashurabad, P.C.1    Kondaiah, P.2    Palika, R.3    Ghosh, S.4    Nair, M.K.5    Raghu, P.6
  • 90
    • 84942627373 scopus 로고    scopus 로고
    • Suboptimal serum α-tocopherol concentrations observed among younger adults and those depending exclusively upon food sources, NHANES 2003-2006
    • McBurney MI, Yu EA, Ciappio ED, Bird JK, Eggersdorfer M, Mehta S. 2015. Suboptimal serum α-tocopherol concentrations observed among younger adults and those depending exclusively upon food sources, NHANES 2003-2006. PLOS ONE 10:e0135510
    • (2015) PLOS ONE , vol.10 , pp. e0135510
    • McBurney, M.I.1    Yu, E.A.2    Ciappio, E.D.3    Bird, J.K.4    Eggersdorfer, M.5    Mehta, S.6
  • 91
    • 60549109477 scopus 로고    scopus 로고
    • Biological activity of lycopene metabolites: Implications for cancer prevention
    • Mein JR, Lian F, Wang XD. 2008. Biological activity of lycopene metabolites: implications for cancer prevention. Nutr. Rev. 66:667-83
    • (2008) Nutr. Rev. , vol.66 , pp. 667-683
    • Mein, J.R.1    Lian, F.2    Wang, X.D.3
  • 92
    • 38549138535 scopus 로고    scopus 로고
    • Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the haptoglobin 2-2 genotype: A prospective double-blinded clinical trial
    • Milman U, Blum S, Shapira C, Aronson D, Miller-Lotan R, et al. 2008. Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the haptoglobin 2-2 genotype: a prospective double-blinded clinical trial. Arterioscler. Thromb. Vasc. Biol. 28:341-47
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 341-347
    • Milman, U.1    Blum, S.2    Shapira, C.3    Aronson, D.4    Miller-Lotan, R.5
  • 93
    • 23644432069 scopus 로고    scopus 로고
    • ATP-binding cassette transporter G8 M429V polymorphism as a novel genetic marker of higher cholesterol absorption in hypercholesterolaemic Japanese subjects
    • Miwa K, Inazu A, Kobayashi J, Higashikata T, Nohara A, et al. 2005. ATP-binding cassette transporter G8 M429V polymorphism as a novel genetic marker of higher cholesterol absorption in hypercholesterolaemic Japanese subjects. Clin. Sci. 109:183-88
    • (2005) Clin. Sci. , vol.109 , pp. 183-188
    • Miwa, K.1    Inazu, A.2    Kobayashi, J.3    Higashikata, T.4    Nohara, A.5
  • 94
    • 84948844241 scopus 로고    scopus 로고
    • Compartmental and noncompartmentalmodeling of 13C-lycopene absorption, isomerization, and distribution kinetics in healthy adults
    • Moran NE, Cichon MJ, Riedl KM, Grainger EM, Schwartz SJ, et al. 2015. Compartmental and noncompartmentalmodeling of 13C-lycopene absorption, isomerization, and distribution kinetics in healthy adults. Am. J. Clin. Nutr. 102:1436-49
    • (2015) Am. J. Clin. Nutr. , vol.102 , pp. 1436-1449
    • Moran, N.E.1    Cichon, M.J.2    Riedl, K.M.3    Grainger, E.M.4    Schwartz, S.J.5
  • 97
    • 77958025244 scopus 로고    scopus 로고
    • Structure and function of the human breast cancer resistance protein (BCRP/ABCG2)
    • Ni Z, Bikadi Z, Rosenberg MF, Mao Q. 2010. Structure and function of the human breast cancer resistance protein (BCRP/ABCG2). Curr. Drug Metab. 11:603-17
    • (2010) Curr. Drug Metab. , vol.11 , pp. 603-617
    • Ni, Z.1    Bikadi, Z.2    Rosenberg, M.F.3    Mao, Q.4
  • 98
    • 84885830507 scopus 로고    scopus 로고
    • Vitamin E secretion by Caco-2 monolayers to APOA1, but not to HDL, is vitamer selective
    • Nicod N, Parker RS. 2013. Vitamin E secretion by Caco-2 monolayers to APOA1, but not to HDL, is vitamer selective. J. Nutr. 143:1565-72
    • (2013) J. Nutr. , vol.143 , pp. 1565-1572
    • Nicod, N.1    Parker, R.S.2
  • 99
    • 84872196547 scopus 로고    scopus 로고
    • A randomized trial of genetic information for personalized nutrition
    • Nielsen DE, El-Sohemy A. 2012. A randomized trial of genetic information for personalized nutrition. Genes Nutr. 7:559-66
    • (2012) Genes Nutr. , vol.7 , pp. 559-566
    • Nielsen, D.E.1    El-Sohemy, A.2
  • 100
    • 84922080203 scopus 로고    scopus 로고
    • Effect of compounds affecting ABCA1 expression and CETP activity on the HDL pathway involved in intestinal absorption of lutein and zeaxanthin
    • Niesor EJ, Chaput E, Mary JL, Staempfli A, Topp A, et al. 2014. Effect of compounds affecting ABCA1 expression and CETP activity on the HDL pathway involved in intestinal absorption of lutein and zeaxanthin. Lipids 49:1233-43
    • (2014) Lipids , vol.49 , pp. 1233-1243
    • Niesor, E.J.1    Chaput, E.2    Mary, J.L.3    Staempfli, A.4    Topp, A.5
  • 102
    • 84919686113 scopus 로고    scopus 로고
    • Common variants in CYP2R1 andGCgenes are both determinants of serum 25-hydroxyvitaminDconcentrations afterUVBirradiation and after consumption of Vitamin D3-fortified bread and milk during winter in Denmark
    • Nissen J,Vogel U, Ravn-HarenG, Andersen EW, Madsen KH, et al. 2015. Common variants in CYP2R1 andGCgenes are both determinants of serum 25-hydroxyvitaminDconcentrations afterUVBirradiation and after consumption of Vitamin D3-fortified bread and milk during winter in Denmark. Am. J. Clin. Nutr. 101:218-27
    • (2015) Am. J. Clin. Nutr. , vol.101 , pp. 218-227
    • Nissen, J.1    Vogel, U.2    Ravn-Haren, G.3    Andersen, E.W.4    Madsen, K.H.5
  • 104
    • 0036403449 scopus 로고    scopus 로고
    • Phytosterols in human nutrition
    • Ostlund RE Jr. 2002. Phytosterols in human nutrition. Annu. Rev. Nutr. 22:533-49
    • (2002) Annu. Rev. Nutr. , vol.22 , pp. 533-549
    • Ostlund, R.E.1
  • 105
    • 0034987262 scopus 로고    scopus 로고
    • Vitamin E, cancer, and apoptosis
    • Papas A, Vos E. 2001. Vitamin E, cancer, and apoptosis. Am. J. Clin. Nutr. 73:1113-14
    • (2001) Am. J. Clin. Nutr. , vol.73 , pp. 1113-1114
    • Papas, A.1    Vos, E.2
  • 106
    • 84995894036 scopus 로고    scopus 로고
    • A systematic review of global α-tocopherol status as assessed by nutritional intake levels and blood serum concentrations
    • In press.
    • Peter S, Friedel A, Roos FF, Wyss A, Eggersdorfer M, et al. 2018. A systematic review of global α-tocopherol status as assessed by nutritional intake levels and blood serum concentrations. Int. J. Vitam. Nutr. Res. In press. https://doi.org/10.1024/0300-9831/a000281
    • (2018) Int. J. Vitam. Nutr. Res.
    • Peter, S.1    Friedel, A.2    Roos, F.F.3    Wyss, A.4    Eggersdorfer, M.5
  • 107
    • 84940533486 scopus 로고    scopus 로고
    • Mechanisms underlying the health benefits of plant sterol and stanol ester consumption
    • Plat J, Baumgartner S, Mensink RP. 2015. Mechanisms underlying the health benefits of plant sterol and stanol ester consumption. J. AOAC Int. 98:697-700
    • (2015) J. AOAC Int. , vol.98 , pp. 697-700
    • Plat, J.1    Baumgartner, S.2    Mensink, R.P.3
  • 108
    • 11244310636 scopus 로고    scopus 로고
    • Common sequence variations in ABCG8 are related to plant sterol metabolism in healthy volunteers
    • Plat J, BragtMC, Mensink RP. 2004. Common sequence variations in ABCG8 are related to plant sterol metabolism in healthy volunteers. J. Lipid Res. 46:68-75
    • (2004) J. Lipid Res. , vol.46 , pp. 68-75
    • Plat, J.1    Bragt, M.C.2    Mensink, R.P.3
  • 109
    • 0034766047 scopus 로고    scopus 로고
    • Vitamin E supplementation in the prevention of coronary heart disease
    • Pruthi S, Allison TG, Hensrud DD. 2001. Vitamin E supplementation in the prevention of coronary heart disease. Mayo Clinic Proc. 76:1131-36
    • (2001) Mayo Clinic Proc. , vol.76 , pp. 1131-1136
    • Pruthi, S.1    Allison, T.G.2    Hensrud, D.D.3
  • 110
    • 34047160095 scopus 로고    scopus 로고
    • Carotenoids and human health
    • Rao AV, Rao LG. 2007. Carotenoids and human health. Pharmacol. Res. 55:207-16
    • (2007) Pharmacol. Res. , vol.55 , pp. 207-216
    • Rao, A.V.1    Rao, L.G.2
  • 111
    • 79960676392 scopus 로고    scopus 로고
    • Proteins involved in uptake, intracellular transport and basolateral secretion of fat-soluble vitamins and carotenoids by mammalian enterocytes
    • Reboul E, Borel P. 2011. Proteins involved in uptake, intracellular transport and basolateral secretion of fat-soluble vitamins and carotenoids by mammalian enterocytes. Prog. Lipid Res. 50:388-402
    • (2011) Prog. Lipid Res. , vol.50 , pp. 388-402
    • Reboul, E.1    Borel, P.2
  • 112
    • 79955595071 scopus 로고    scopus 로고
    • Vitamin D intestinal absorption is not a simple passive diffusion: Evidences for involvement of cholesterol transporters
    • Reboul E, Goncalves A, Comera C, Bott R, Nowicki M, et al. 2011. Vitamin D intestinal absorption is not a simple passive diffusion: evidences for involvement of cholesterol transporters. Mol. Nutr. Food Res. 55:691-702
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 691-702
    • Reboul, E.1    Goncalves, A.2    Comera, C.3    Bott, R.4    Nowicki, M.5
  • 113
    • 84995511726 scopus 로고    scopus 로고
    • Lifestyle and other factors explain onehalf of the variability in the serum 25-hydroxyvitamin D response to cholecalciferol supplementation in healthy adults
    • Rees JR,Mott LA, Barry EL, Baron JA, Bostick RM, et al. 2016. Lifestyle and other factors explain onehalf of the variability in the serum 25-hydroxyvitamin D response to cholecalciferol supplementation in healthy adults. J. Nutr. 146:2312-24
    • (2016) J. Nutr. , vol.146 , pp. 2312-2324
    • Rees, J.R.1    Mott, L.A.2    Barry, E.L.3    Baron, J.A.4    Bostick, R.M.5
  • 115
    • 35349012592 scopus 로고    scopus 로고
    • Genome-wide detection and characterization of positive selection in human populations
    • Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, et al. 2007. Genome-wide detection and characterization of positive selection in human populations. Nature 449:913-18
    • (2007) Nature , vol.449 , pp. 913-918
    • Sabeti, P.C.1    Varilly, P.2    Fry, B.3    Lohmueller, J.4    Hostetter, E.5
  • 116
    • 85030528385 scopus 로고    scopus 로고
    • RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye
    • Shyam R, Gorusupudi A, Nelson K, HorvathMP, Bernstein PS. 2017. RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye. PNAS 114:10882-87
    • (2017) PNAS , vol.114 , pp. 10882-10887
    • Shyam, R.1    Gorusupudi, A.2    Nelson, K.3    Horvath, M.P.4    Bernstein, P.S.5
  • 119
    • 0035195703 scopus 로고    scopus 로고
    • Apolipoprotein e phenotype regulates cholesterol absorption in healthy 13-month-old children\-The STRIP study
    • Tammi A, Ronnemaa T, Rask-Nissila L, Miettinen TA, Gylling H, et al. 2001. Apolipoprotein E phenotype regulates cholesterol absorption in healthy 13-month-old children\-The STRIP study. Pediatr. Res. 50:688-91
    • (2001) Pediatr. Res. , vol.50 , pp. 688-691
    • Tammi, A.1    Ronnemaa, T.2    Rask-Nissila, L.3    Miettinen, T.A.4    Gylling, H.5
  • 120
    • 77956824626 scopus 로고    scopus 로고
    • Genetic regulation of serum phytosterol levels and risk of coronary artery disease
    • Teupser D, Baber R, Ceglarek U, Scholz M, Illig T, et al. 2010. Genetic regulation of serum phytosterol levels and risk of coronary artery disease. Circ. Cardiovasc. Genet. 3:331-39
    • (2010) Circ. Cardiovasc. Genet. , vol.3 , pp. 331-339
    • Teupser, D.1    Baber, R.2    Ceglarek, U.3    Scholz, M.4    Illig, T.5
  • 121
    • 84990913648 scopus 로고    scopus 로고
    • Mechanisms of selective delivery of xanthophylls to retinal pigment epithelial cells by human lipoproteins
    • Thomas SE, Harrison EH. 2016. Mechanisms of selective delivery of xanthophylls to retinal pigment epithelial cells by human lipoproteins. J. Lipid Res. 57:1865-78
    • (2016) J. Lipid Res. , vol.57 , pp. 1865-1878
    • Thomas, S.E.1    Harrison, E.H.2
  • 122
    • 70349746749 scopus 로고    scopus 로고
    • Functional polymorphism in manganese superoxide dismutase and antioxidant status: Their interactions on the risk of cervical intraepithelial neoplasia and cervical cancer
    • Tong SY, Lee JM, Song ES, Lee KB, Kim MK, et al. 2009. Functional polymorphism in manganese superoxide dismutase and antioxidant status: their interactions on the risk of cervical intraepithelial neoplasia and cervical cancer. Gynecol. Oncol. 115:272-76
    • (2009) Gynecol. Oncol. , vol.115 , pp. 272-276
    • Tong, S.Y.1    Lee, J.M.2    Song, E.S.3    Lee, K.B.4    Kim, M.K.5
  • 123
    • 33846182968 scopus 로고    scopus 로고
    • Heart disease and single-vitamin supplementation
    • Traber MG. 2007. Heart disease and single-vitamin supplementation. Am. J. Clin. Nutr. 85:293S-99S
    • (2007) Am. J. Clin. Nutr. , vol.85 , pp. 293S-299S
    • Traber, M.G.1
  • 124
    • 84910138890 scopus 로고    scopus 로고
    • Vitamin E inadequacy in humans: Causes and consequences
    • Traber MG. 2014. Vitamin E inadequacy in humans: causes and consequences. Adv. Nutr. 5:503-14
    • (2014) Adv. Nutr. , vol.5 , pp. 503-514
    • Traber, M.G.1
  • 125
    • 0029798873 scopus 로고    scopus 로고
    • Vitamin E in humans: Demand and delivery
    • Traber MG, Sies H. 1996. Vitamin E in humans: demand and delivery. Annu. Rev. Nutr. 16:321-47
    • (1996) Annu. Rev. Nutr. , vol.16 , pp. 321-347
    • Traber, M.G.1    Sies, H.2
  • 126
    • 84865215720 scopus 로고    scopus 로고
    • Dietary surveys indicate Vitamin intakes below recommendations are common in representativeWestern countries
    • Troesch B, Hoeft B, McBurney M, Eggersdorfer M, Weber P. 2012. Dietary surveys indicate Vitamin intakes below recommendations are common in representativeWestern countries. Br. J. Nutr. 108:692-98
    • (2012) Br. J. Nutr. , vol.108 , pp. 692-698
    • Troesch, B.1    Hoeft, B.2    McBurney, M.3    Eggersdorfer, M.4    Weber, P.5
  • 127
    • 0037214156 scopus 로고    scopus 로고
    • Isotopic tracer techniques for studying the bioavailability and bioefficacy of dietary carotenoids, particularly β-carotene, in humans: A review
    • van Lieshout M, West CE, van Breemen RB. 2003. Isotopic tracer techniques for studying the bioavailability and bioefficacy of dietary carotenoids, particularly β-carotene, in humans: a review. Am. J. Clin. Nutr. 77:12-28
    • (2003) Am. J. Clin. Nutr. , vol.77 , pp. 12-28
    • Van Lieshout, M.1    West, C.E.2    Van Breemen, R.B.3
  • 128
    • 78649681796 scopus 로고    scopus 로고
    • TheMicronutrient Genomics Project: A community-driven knowledge base for micronutrient research
    • van Ommen B, El-Sohemy A, Hesketh J, Kaput J, Fenech M, et al. 2010. TheMicronutrient Genomics Project: a community-driven knowledge base for micronutrient research. Genes Nutr. 5:285-96
    • (2010) Genes Nutr. , vol.5 , pp. 285-296
    • Van Ommen, B.1    El-Sohemy, A.2    Hesketh, J.3    Kaput, J.4    Fenech, M.5
  • 129
    • 0037237823 scopus 로고    scopus 로고
    • Efficiency of intestinal cholesterol absorption in humans is not related to apoE phenotype
    • Von Bergmann K, Lutjohann D, Lindenthal B, Steinmetz A. 2003. Efficiency of intestinal cholesterol absorption in humans is not related to apoE phenotype. J. Lipid Res. 44:193-97
    • (2003) J. Lipid Res. , vol.44 , pp. 193-197
    • Von Bergmann, K.1    Lutjohann, D.2    Lindenthal, B.3    Steinmetz, A.4
  • 130
    • 33947380185 scopus 로고    scopus 로고
    • Regulation of intestinal cholesterol absorption
    • Wang DQ. 2007. Regulation of intestinal cholesterol absorption. Annu. Rev. Physiol. 69:221-48
    • (2007) Annu. Rev. Physiol. , vol.69 , pp. 221-248
    • Wang, D.Q.1
  • 131
    • 84892438386 scopus 로고    scopus 로고
    • Strong and weak plasma response to dietary carotenoids identified by cluster analysis and linked to beta-carotene 15,15-monooxygenase 1 single nucleotide polymorphisms
    • Wang TT, Edwards AJ, Clevidence BA. 2013. Strong and weak plasma response to dietary carotenoids identified by cluster analysis and linked to beta-carotene 15,15-monooxygenase 1 single nucleotide polymorphisms. J. Nutr. Biochem. 24:1538-46
    • (2013) J. Nutr. Biochem. , vol.24 , pp. 1538-1546
    • Wang, T.T.1    Edwards, A.J.2    Clevidence, B.A.3
  • 132
    • 84959441627 scopus 로고    scopus 로고
    • Lycopene, tomato products and prostate cancer-specific mortality among men diagnosed with nonmetastatic prostate cancer in the Cancer Prevention Study-II Nutrition Cohort
    • Wang Y, Jacobs EJ, Newton CC, McCullough ML. 2016. Lycopene, tomato products and prostate cancer-specific mortality among men diagnosed with nonmetastatic prostate cancer in the Cancer Prevention Study-II Nutrition Cohort. Int. J. Cancer 138:2846-55
    • (2016) Int. J. Cancer , vol.138 , pp. 2846-2855
    • Wang, Y.1    Jacobs, E.J.2    Newton, C.C.3    McCullough, M.L.4
  • 133
    • 84904052549 scopus 로고    scopus 로고
    • Environmental, personal, and genetic determinants of response to Vitamin D supplementation in older adults
    • Waterhouse M, Tran B, Armstrong BK, Baxter C, Ebeling PR, et al. 2014. Environmental, personal, and genetic determinants of response to Vitamin D supplementation in older adults. J. Clin. Endocrinol. Metab. 99:E1332-40
    • (2014) J. Clin. Endocrinol. Metab. , vol.99 , pp. E1332-E1340
    • Waterhouse, M.1    Tran, B.2    Armstrong, B.K.3    Baxter, C.4    Ebeling, P.R.5
  • 134
    • 84858325332 scopus 로고    scopus 로고
    • The contribution of β-carotene to Vitamin A supply of humans
    • Weber D, Grune T. 2012. The contribution of β-carotene to Vitamin A supply of humans. Mol. Nutr. Food Res. 56:251-58
    • (2012) Mol. Nutr. Food Res. , vol.56 , pp. 251-258
    • Weber, D.1    Grune, T.2
  • 135
    • 0031775340 scopus 로고    scopus 로고
    • Quantification of the "SLAMENGHI" factors for carotenoid bioavailability and bioconversion
    • West CE, Castenmiller JJ. 1998. Quantification of the "SLAMENGHI" factors for carotenoid bioavailability and bioconversion. Int. J. Vitam. Nutr. Res. 68:371-77
    • (1998) Int. J. Vitam. Nutr. Res. , vol.68 , pp. 371-377
    • West, C.E.1    Castenmiller, J.J.2
  • 136
    • 84930698230 scopus 로고    scopus 로고
    • Agenetic dissection of intestinal fat-soluble Vitamin and carotenoid absorption
    • Widjaja-AdhiMA,Lobo GP,Golczak M, VonLintig J. 2015.Agenetic dissection of intestinal fat-soluble Vitamin and carotenoid absorption. Hum. Mol. Genet. 24:3206-19
    • (2015) Hum Mol. Genet. , vol.24 , pp. 3206-3219
    • Widjaja-Adhi, M.A.1    Lobo, G.P.2    Golczak, M.3    VonLintig, J.4
  • 137
    • 85007339826 scopus 로고    scopus 로고
    • Common SNP rs6564851 in the BCO1 gene affects the circulating levels of β-carotene and the daily intake of carotenoids in healthy Japanese women
    • Yabuta S, Urata M, Wai Kun RY, Masaki M, Shidoji Y. 2016. Common SNP rs6564851 in the BCO1 gene affects the circulating levels of β-carotene and the daily intake of carotenoids in healthy Japanese women. PLOS ONE 11:e0168857
    • (2016) PLOS ONE , vol.11 , pp. e0168857
    • Yabuta, S.1    Urata, M.2    Wai Kun, R.Y.3    Masaki, M.4    Shidoji, Y.5
  • 138
    • 85010527289 scopus 로고    scopus 로고
    • Effects of genetic and nongenetic factors on total and bioavailable 25(OH)D responses to Vitamin D supplementation
    • Yao P, Sun L, Lu L, Ding H, Chen X, et al. 2017. Effects of genetic and nongenetic factors on total and bioavailable 25(OH)D responses to Vitamin D supplementation. J. Clin. Endocrinol. Metab. 102:100-10
    • (2017) J. Clin. Endocrinol. Metab. , vol.102 , pp. 100-110
    • Yao, P.1    Sun, L.2    Lu, L.3    Ding, H.4    Chen, X.5
  • 139
    • 84882750014 scopus 로고    scopus 로고
    • Candidate gene study of macular response to supplemental lutein and zeaxanthin
    • Yonova-Doing E, Hysi PG, Venturini C, Williams KM, Nag A, et al. 2013. Candidate gene study of macular response to supplemental lutein and zeaxanthin. Exp. Eye Res. 115:172-77
    • (2013) Exp. Eye Res. , vol.115 , pp. 172-177
    • Yonova-Doing, E.1    Hysi, P.G.2    Venturini, C.3    Williams, K.M.4    Nag, A.5
  • 140
    • 85009495386 scopus 로고    scopus 로고
    • SNP rs11185644 of RXRA gene is identified for dose-response variability to vitaminD3 supplementation: A randomized clinical trial
    • ZhangM, Zhao LJ, Zhou Y, Badr R, Watson P, et al. 2017. SNP rs11185644 of RXRA gene is identified for dose-response variability to vitaminD3 supplementation: a randomized clinical trial. Sci. Rep. 7:40593
    • (2017) Sci. Rep. , vol.7 , pp. 40593
    • Zhang, M.1    Zhao, L.J.2    Zhou, Y.3    Badr, R.4    Watson, P.5
  • 141
    • 84906789954 scopus 로고    scopus 로고
    • DNA methylation levels of CYP2R1 and CYP24A1 predict Vitamin D response variation
    • Pt. A
    • Zhou Y, Zhao LJ, Xu X, Ye A, Travers-Gustafson D, et al. 2014. DNA methylation levels of CYP2R1 and CYP24A1 predict Vitamin D response variation. J. Steroid Biochem. Mol. Biol. 144(Pt. A):207-14
    • (2014) J. Steroid Biochem. Mol. Biol. , vol.144 , pp. 207-214
    • Zhou, Y.1    Zhao, L.J.2    Xu, X.3    Ye, A.4    Travers-Gustafson, D.5
  • 142
    • 84884597662 scopus 로고    scopus 로고
    • CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo
    • Zhu JG, Ochalek JT, Kaufmann M, Jones G, Deluca HF. 2013. CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo. PNAS 110:15650-55
    • (2013) PNAS , vol.110 , pp. 15650-15655
    • Zhu, J.G.1    Ochalek, J.T.2    Kaufmann, M.3    Jones, G.4    Deluca, H.F.5
  • 143
    • 35448977648 scopus 로고    scopus 로고
    • Vitamin E: An overview of major research directions
    • Zingg JM. 2007. Vitamin E: an overview of major research directions. Mol. Aspects Med. 28:400-22
    • (2007) Mol. Aspects Med. , vol.28 , pp. 400-422
    • Zingg, J.M.1
  • 144
    • 84937577294 scopus 로고    scopus 로고
    • Vitamin E: A role in signal transduction
    • Zingg JM. 2015. Vitamin E: a role in signal transduction. Annu. Rev. Nutr. 35:135-73
    • (2015) Annu. Rev. Nutr. , vol.35 , pp. 135-173
    • Zingg, J.M.1
  • 145
    • 2342502657 scopus 로고    scopus 로고
    • Non-antioxidant activities of Vitamin E
    • Zingg JM, Azzi A. 2004. Non-antioxidant activities of Vitamin E. Curr. Med. Chem. 11:1113-33
    • (2004) Curr. Med. Chem. , vol.11 , pp. 1113-1133
    • Zingg, J.M.1    Azzi, A.2
  • 146
    • 47349106545 scopus 로고    scopus 로고
    • Genetic polymorphisms as determinants for disease-preventive effects of Vitamin E
    • Zingg JM, Azzi A, Meydani M. 2008. Genetic polymorphisms as determinants for disease-preventive effects of Vitamin E. Nutr. Rev. 66:406-14
    • (2008) Nutr. Rev. , vol.66 , pp. 406-414
    • Zingg, J.M.1    Azzi, A.2    Meydani, M.3
  • 147
    • 84940676345 scopus 로고    scopus 로고
    • Lycopene reduces cholesterol absorption through the downregulation ofNiemann-Pick C1-like 1 in Caco-2 cells
    • Zou J, FengD. 2015. Lycopene reduces cholesterol absorption through the downregulation ofNiemann-Pick C1-like 1 in Caco-2 cells. Mol. Nutr. Food Res. 59:2225-30
    • (2015) Mol. Nutr. Food Res. , vol.59 , pp. 2225-2230
    • Zou, J.1    Feng, D.2


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