Vitamin E decreases bone mass by stimulating osteoclast fusion

Nature Medicine

Volumn 18, Issue 4, 2012, Pages 589-594

  Fujita, Koji ^a   Iwasaki, Makiko ^a   Ochi, Hiroki ^b   Fukuda, Toru ^b   Ma, Chengshan ^a   Miyamoto, Takeshi ^b   Takitani, Kimitaka ^c   Negishi Koga, Takako ^a   Sunamura, Satoko ^d   Kodama, Tatsuhiko ^d   Takayanagi, Hiroshi ^a   Tamai, Hiroshi ^c   Kato, Shigeaki ^d   Arai, Hiroyuki ^d   Shinomiya, Kenichi ^a   Itoh, Hiroshi ^b   Okawa, Atsushi ^a   Takeda, Shu ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c OSAKA MEDICAL COLLEGE   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; MEMBRANE PROTEIN; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 14;

ALPHA TOCOPHEROL DEFICIENCY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MASS; CELL ASSAY; CONTROLLED STUDY; DENDRITIC CELL; MOUSE; NONHUMAN; OSTEOCLAST ACTIVITY; OSTEOLYSIS; PRIORITY JOURNAL; REGULATORY MECHANISM; TRANSGENE; VITAMIN SUPPLEMENTATION;

ALPHA-TOCOPHEROL; AMINO ACIDS; ANIMALS; APOPTOSIS; BONE AND BONES; BONE RESORPTION; BROMODEOXYURIDINE; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; IN SITU NICK-END LABELING; MACROPHAGE COLONY-STIMULATING FACTOR; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MITOGEN-ACTIVATED PROTEIN KINASE 14; NITROPHENOLS; OSTEOCLASTS; OSTEOCYTES; RANK LIGAND; RATS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOMOGRAPHY, X-RAY COMPUTED; TRANSFECTION; VITAMIN E; VITAMIN E DEFICIENCY; VITAMINS;

MUS; RATTUS;

EID: 84859597301     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2659     Document Type: Article

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