Herpes simplex virus 1 tegument protein VP22 abrogates cGAS/ STING-mediated antiviral innate immunity

Journal of Virology

Volumn 92, Issue 15, 2018, Pages

  Huang, Jian ^a   You, Hongjuan ^a,d   Su, Chenhe ^e   Li, Yangxin ^f   Chen, Shunhua ^g   Zheng, Chunfu ^b,c  

^a SOOCHOW UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF CALGARY   (Canada)

^d XUZHOU MEDICAL UNIVERSITY   (China)

^e MCGILL UNIVERSITY   (Canada)

^f THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^g NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

CGAS; DNA sensing; HSV 1; VP22

Indexed keywords

BETA INTERFERON; CYCLIC GMP AMP SYNTHASE; PROTEIN VP22; SYNTHETASE; UNCLASSIFIED DRUG; HERPES SIMPLEX VIRUS TYPE 1 PROTEIN VP22; MB21D1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MPYS PROTEIN, HUMAN; NUCLEOTIDYLTRANSFERASE; VIRAL PROTEIN;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ECTOPIC EXPRESSION; ENZYME ACTIVITY; HUMAN ALPHAHERPESVIRUS 1; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION; VIRUS REPLICATION; ANIMAL; CHLOROCEBUS AETHIOPS; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; VERO CELL LINE;

ANIMALS; CERCOPITHECUS AETHIOPS; HEK293 CELLS; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNITY, INNATE; INTERFERON-BETA; MEMBRANE PROTEINS; NUCLEOTIDYLTRANSFERASES; SIGNAL TRANSDUCTION; VERO CELLS; VIRAL STRUCTURAL PROTEINS;

EID: 85050154854     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00841-18     Document Type: Article

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