Herpes simplex virus 1 UL24 abrogates the DNA sensing signal pathway by inhibiting NF-κB activation

Journal of Virology

Volumn 91, Issue 7, 2017, Pages

  Xu, Haiyan ^a   Su, Chenhe ^a   Pearson, Angela ^b   Mody, Christopher H ^c   Zheng, Chunfu ^a,c  

^a SOOCHOW UNIVERSITY   (China)

^b INRS INSTITUT ARMAND FRAPPIER   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

DNA sensor; HSV 1; NF B; P65; UL24

Indexed keywords

AMINO ACID; BETA INTERFERON; CYCLIC AMP; CYCLIC GMP; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; PATTERN RECOGNITION RECEPTOR; TRANSCRIPTION FACTOR REL; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR; UL24 PROTEIN; UNCLASSIFIED DRUG; VIRAL PROTEIN; VIRUS DNA; IL6 PROTEIN, HUMAN; PROTEIN BINDING; RELA PROTEIN, HUMAN; UL24 PROTEIN, HUMAN HERPESVIRUS 1;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE TRANSLOCATION; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; INNATE IMMUNITY; MUTATIONAL ANALYSIS; NONHUMAN; PERSISTENT INFECTION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; ANIMAL; CHLOROCEBUS AETHIOPS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HOST PATHOGEN INTERACTION; HUMAN; METABOLISM; NUCLEOCYTOPLASMIC TRANSPORT; PHYSIOLOGY; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; VERO CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CERCOPITHECUS AETHIOPS; GENE EXPRESSION REGULATION, VIRAL; HEK293 CELLS; HELA CELLS; HERPESVIRUS 1, HUMAN; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON-BETA; INTERLEUKIN-6; NF-KAPPA B P50 SUBUNIT; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; VERO CELLS; VIRAL PROTEINS;

EID: 85015156314     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00025-17     Document Type: Article

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