Herpes simplex virus 1 abrogates the cGAS/STING-mediated cytosolic DNA-sensing pathway via its virion host shutoff protein, UL41

Journal of Virology

Volumn 91, Issue 6, 2017, Pages

  Su, Chenhe ^a   Zheng, Chunfu ^a,b  

^a SOOCHOW UNIVERSITY   (China)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

CGAS; DNA sensing; HSV 1; Vhs UL41

Indexed keywords

ADAPTOR PROTEIN; BETA INTERFERON; CYCLIC GMP AMP SYNTHASE; MESSENGER RNA; NUCLEOTIDYLTRANSFERASE; RIBONUCLEASE; STIMULATOR OF INTERFERON GENE PROTEIN; UL41 PROTEIN; UNCLASSIFIED DRUG; VIRUS DNA; MB21D1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MPYS PROTEIN, HUMAN; UL41 PROTEIN, HUMAN HERPESVIRUS 1; VIRAL PROTEIN;

ARTICLE; CONTROLLED STUDY; ECTOPIC EXPRESSION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNE EVASION; INTERFERON PRODUCTION; INTERFERON SIGNALING PATHWAY; NONHUMAN; PROMOTER REGION; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; VIRUS REPLICATION; ANTAGONISTS AND INHIBITORS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PATHOGENICITY; PHYSIOLOGY;

DNA, VIRAL; HERPESVIRUS 1, HUMAN; HOST-PATHOGEN INTERACTIONS; IMMUNE EVASION; IMMUNITY, INNATE; MEMBRANE PROTEINS; NUCLEOTIDYLTRANSFERASES; VIRAL PROTEINS;

EID: 85014083284     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02414-16     Document Type: Article

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