-
1
-
-
84868555271
-
-
Available from , Accessed 13 Nov 2017
-
International Diabetes Federation (2017) Diabetes Atlas, 8th edn. Available from http://www.diabetesatlas.org/. Accessed 13 Nov 2017
-
(2017)
Diabetes Atlas, 8Th Edn
-
-
-
2
-
-
85039703274
-
2. Classification and diagnosis of diabetes: standards of medical care in diabetes—2018
-
American Diabetes Association (2018) 2. Classification and diagnosis of diabetes: standards of medical care in diabetes—2018. Diabetes Care 41(Suppl 1):S13–S27
-
(2018)
Diabetes Care
, vol.41
, pp. S13-S27
-
-
-
3
-
-
0032742992
-
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
-
PID: 10491414
-
Weyer C, Bogardus C, Mott DM, Pratley RE (1999) The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104:787–794
-
(1999)
J Clin Invest
, vol.104
, pp. 787-794
-
-
Weyer, C.1
Bogardus, C.2
Mott, D.M.3
Pratley, R.E.4
-
4
-
-
23644443235
-
Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin
-
PID: 16046308
-
Kitabchi AE, Temprosa M, Knowler WC et al (2005) Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin. Diabetes 54:2404–2414
-
(2005)
Diabetes
, vol.54
, pp. 2404-2414
-
-
Kitabchi, A.E.1
Temprosa, M.2
Knowler, W.C.3
-
5
-
-
62449169287
-
Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study
-
PID: 18931095
-
Nauck M, Frid A, Hermansen K et al (2009) Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study. Diabetes Care 32:84–90
-
(2009)
Diabetes Care
, vol.32
, pp. 84-90
-
-
Nauck, M.1
Frid, A.2
Hermansen, K.3
-
6
-
-
84884167643
-
Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial
-
PID: 23850055
-
Cefalu WT, Leiter LA, Yoon KH et al (2013) Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial. Lancet 382:941–950
-
(2013)
Lancet
, vol.382
, pp. 941-950
-
-
Cefalu, W.T.1
Leiter, L.A.2
Yoon, K.H.3
-
7
-
-
85017393067
-
Pharmacological approach to understanding the control of insulin secretion in human islets
-
PID: 28116849
-
Henquin JC, Dufrane D, Gmyr V, Kerr-Conte J, Nenquin M (2017) Pharmacological approach to understanding the control of insulin secretion in human islets. Diabetes Obes Metab 19:1061–1070
-
(2017)
Diabetes Obes Metab
, vol.19
, pp. 1061-1070
-
-
Henquin, J.C.1
Dufrane, D.2
Gmyr, V.3
Kerr-Conte, J.4
Nenquin, M.5
-
8
-
-
33845405222
-
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
-
PID: 17145742
-
Kahn SE, Haffner SM, Heise MA et al (2006) Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 355:2427–2443
-
(2006)
N Engl J Med
, vol.355
, pp. 2427-2443
-
-
Kahn, S.E.1
Haffner, S.M.2
Heise, M.A.3
-
9
-
-
79959484802
-
Effects of rosiglitazone, glyburide, and metformin on β-cell function and insulin sensitivity in ADOPT
-
PID: 21415383
-
Kahn SE, Lachin JM, Zinman B et al (2011) Effects of rosiglitazone, glyburide, and metformin on β-cell function and insulin sensitivity in ADOPT. Diabetes 60:1552–1560
-
(2011)
Diabetes
, vol.60
, pp. 1552-1560
-
-
Kahn, S.E.1
Lachin, J.M.2
Zinman, B.3
-
10
-
-
15044359454
-
Dipeptidyl peptidase IV inhibitors: how do they work as new antidiabetic agents?
-
PID: 15780435
-
McIntosh CH, Demuth HU, Pospisilik JA, Pederson R (2005) Dipeptidyl peptidase IV inhibitors: how do they work as new antidiabetic agents? Regul Pept 128:159–165
-
(2005)
Regul Pept
, vol.128
, pp. 159-165
-
-
McIntosh, C.H.1
Demuth, H.U.2
Pospisilik, J.A.3
Pederson, R.4
-
11
-
-
84925282923
-
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
-
PID: 25485909
-
Finan B, Yang B, Ottaway N et al (2015) A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents. Nat Med 21:27–36
-
(2015)
Nat Med
, vol.21
, pp. 27-36
-
-
Finan, B.1
Yang, B.2
Ottaway, N.3
-
12
-
-
77949387699
-
Safety and efficacy of treatment with sitagliptin or glipizide in patients with type 2 diabetes inadequately controlled on metformin: a 2-year study
-
PID: 20456211
-
Seck T, Nauck M, Sheng D et al (2010) Safety and efficacy of treatment with sitagliptin or glipizide in patients with type 2 diabetes inadequately controlled on metformin: a 2-year study. Int J Clin Pract 64:562–576
-
(2010)
Int J Clin Pract
, vol.64
, pp. 562-576
-
-
Seck, T.1
Nauck, M.2
Sheng, D.3
-
13
-
-
79953232077
-
Pioglitazone for diabetes prevention in impaired glucose tolerance
-
PID: 21428766
-
DeFronzo RA, Tripathy D, Schwenke DC et al (2011) Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med 364:1104–1115
-
(2011)
N Engl J Med
, vol.364
, pp. 1104-1115
-
-
DeFronzo, R.A.1
Tripathy, D.2
Schwenke, D.C.3
-
14
-
-
84893872877
-
Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients
-
PID: 24463454
-
Ferrannini E, Muscelli E, Frascerra S et al (2014) Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients. J Clin Invest 124:499–508
-
(2014)
J Clin Invest
, vol.124
, pp. 499-508
-
-
Ferrannini, E.1
Muscelli, E.2
Frascerra, S.3
-
15
-
-
85044524122
-
Mechanisms of weight loss and improved metabolism following bariatric surgery
-
PID: 28868615
-
Mulla CM, Middelbeek RJW, Patti ME (2018) Mechanisms of weight loss and improved metabolism following bariatric surgery. Ann N Y Acad Sci 1411:53–64
-
(2018)
Ann N Y Acad Sci
, vol.1411
, pp. 53-64
-
-
Mulla, C.M.1
Middelbeek, R.J.W.2
Patti, M.E.3
-
16
-
-
84899914501
-
Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus
-
PID: 24552216
-
Oh E, Stull ND, Mirmira RG, Thurmond DC (2014) Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus. J Clin Endocrinol Metab 99:E866–E870
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. E866-E870
-
-
Oh, E.1
Stull, N.D.2
Mirmira, R.G.3
Thurmond, D.C.4
-
17
-
-
84940646328
-
Syntaxin 4 overexpression ameliorates effects of aging and high-fat diet on glucose control and extends lifespan
-
PID: 26331606
-
Oh E, Miller RA, Thurmond DC (2015) Syntaxin 4 overexpression ameliorates effects of aging and high-fat diet on glucose control and extends lifespan. Cell Metab 22:499–507
-
(2015)
Cell Metab
, vol.22
, pp. 499-507
-
-
Oh, E.1
Miller, R.A.2
Thurmond, D.C.3
-
18
-
-
84978174650
-
The p21-activated kinase (PAK1) is involved in diet-induced beta cell mass expansion and survival in mice and human islets
-
PID: 27394663
-
Ahn M, Yoder SM, Wang Z et al (2016) The p21-activated kinase (PAK1) is involved in diet-induced beta cell mass expansion and survival in mice and human islets. Diabetologia 59:2145–2155
-
(2016)
Diabetologia
, vol.59
, pp. 2145-2155
-
-
Ahn, M.1
Yoder, S.M.2
Wang, Z.3
-
19
-
-
84908324599
-
Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells
-
PID: 25199455
-
Tunduguru R, Chiu TT, Ramalingam L, Elmendorf JS, Klip A, Thurmond DC (2014) Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells. Biochem Pharmacol 92:380–388
-
(2014)
Biochem Pharmacol
, vol.92
, pp. 380-388
-
-
Tunduguru, R.1
Chiu, T.T.2
Ramalingam, L.3
Elmendorf, J.S.4
Klip, A.5
Thurmond, D.C.6
-
20
-
-
85012071197
-
Bone morphogenetic protein-7 (BMP-7) augments insulin sensitivity in mice with type II diabetes mellitus by potentiating PI3K/AKT pathway
-
PID: 28186649
-
Chattopadhyay T, Singh RR, Gupta S, Surolia A (2017) Bone morphogenetic protein-7 (BMP-7) augments insulin sensitivity in mice with type II diabetes mellitus by potentiating PI3K/AKT pathway. Biofactors 43:195–209
-
(2017)
Biofactors
, vol.43
, pp. 195-209
-
-
Chattopadhyay, T.1
Singh, R.R.2
Gupta, S.3
Surolia, A.4
-
21
-
-
84957443147
-
BMP-7 induces adult human pancreatic exocrine-to-endocrine conversion
-
PID: 26307584
-
Klein D, Alvarez-Cubela S, Lanzoni G et al (2015) BMP-7 induces adult human pancreatic exocrine-to-endocrine conversion. Diabetes 64:4123–4134
-
(2015)
Diabetes
, vol.64
, pp. 4123-4134
-
-
Klein, D.1
Alvarez-Cubela, S.2
Lanzoni, G.3
-
22
-
-
42449096306
-
Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
-
PID: 18362359
-
Ferron M, Hinoi E, Karsenty G, Ducy P (2008) Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc Natl Acad Sci U S A 105:5266–5270
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 5266-5270
-
-
Ferron, M.1
Hinoi, E.2
Karsenty, G.3
Ducy, P.4
-
23
-
-
84874628208
-
Osteocalcin reverses endoplasmic reticulum stress and improves impaired insulin sensitivity secondary to diet-induced obesity through nuclear factor-κB signaling pathway
-
PID: 23407450
-
Zhou B, Li H, Xu L, Zang W, Wu S, Sun H (2013) Osteocalcin reverses endoplasmic reticulum stress and improves impaired insulin sensitivity secondary to diet-induced obesity through nuclear factor-κB signaling pathway. Endocrinology 154:1055–1068
-
(2013)
Endocrinology
, vol.154
, pp. 1055-1068
-
-
Zhou, B.1
Li, H.2
Xu, L.3
Zang, W.4
Wu, S.5
Sun, H.6
-
24
-
-
34249660144
-
TXNIP regulates peripheral glucose metabolism in humans
-
PID: 17472435
-
Parikh H, Carlsson E, Chutkow WA et al (2007) TXNIP regulates peripheral glucose metabolism in humans. PLoS Med 4:e158
-
(2007)
PLoS Med
, vol.4
-
-
Parikh, H.1
Carlsson, E.2
Chutkow, W.A.3
-
25
-
-
84883793279
-
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
-
PID: 23975026
-
Xu G, Chen J, Jing G, Shalev A (2013) Thioredoxin-interacting protein regulates insulin transcription through microRNA-204. Nat Med 19:1141–1146
-
(2013)
Nat Med
, vol.19
, pp. 1141-1146
-
-
Xu, G.1
Chen, J.2
Jing, G.3
Shalev, A.4
-
26
-
-
84969791239
-
Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents
-
PID: 27213816
-
Scarlett JM, Rojas JM, Matsen ME et al (2016) Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents. Nat Med 22:800–806
-
(2016)
Nat Med
, vol.22
, pp. 800-806
-
-
Scarlett, J.M.1
Rojas, J.M.2
Matsen, M.E.3
-
27
-
-
85034639631
-
Neuronal control of peripheral insulin sensitivity and glucose metabolism
-
PID: 28469281
-
Ruud J, Steculorum SM, Bruning JC (2017) Neuronal control of peripheral insulin sensitivity and glucose metabolism. Nat Commun 8:15259
-
(2017)
Nat Commun
, vol.8
, pp. 15259
-
-
Ruud, J.1
Steculorum, S.M.2
Bruning, J.C.3
-
28
-
-
0242363725
-
No deterioration in glycemic control in HNF-1α maturity-onset diabetes of the young following transfer from long-term insulin to sulphonylureas
-
PID: 14578267
-
Shepherd M, Pearson ER, Houghton J, Salt G, Ellard S, Hattersley AT (2003) No deterioration in glycemic control in HNF-1α maturity-onset diabetes of the young following transfer from long-term insulin to sulphonylureas. Diabetes Care 26:3191–3192
-
(2003)
Diabetes Care
, vol.26
, pp. 3191-3192
-
-
Shepherd, M.1
Pearson, E.R.2
Houghton, J.3
Salt, G.4
Ellard, S.5
Hattersley, A.T.6
-
29
-
-
33746686369
-
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
-
PID: 16885550
-
Pearson ER, Flechtner I, Njolstad PR et al (2006) Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations. N Engl J Med 355:467–477
-
(2006)
N Engl J Med
, vol.355
, pp. 467-477
-
-
Pearson, E.R.1
Flechtner, I.2
Njolstad, P.R.3
-
30
-
-
85042583803
-
Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables
-
PID: 29503172
-
Ahlqvist E, Storm P, Karajamaki A et al (2018) Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables. Lancet Diabetes Endocrinol 6:361–369
-
(2018)
Lancet Diabetes Endocrinol
, vol.6
, pp. 361-369
-
-
Ahlqvist, E.1
Storm, P.2
Karajamaki, A.3
-
31
-
-
4243062602
-
Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action
-
PID: 14551916
-
Barroso I, Luan J, Middelberg RP et al (2003) Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action. PLoS Biol 1:E20
-
(2003)
PLoS Biol
, vol.1
, pp. E20
-
-
Barroso, I.1
Luan, J.2
Middelberg, R.P.3
-
32
-
-
85013785118
-
Genomics of islet (dys)function and type 2 diabetes
-
PID: 28245910
-
Lawlor N, Khetan S, Ucar D, Stitzel ML (2017) Genomics of islet (dys)function and type 2 diabetes. Trends Genet 33:244–255
-
(2017)
Trends Genet
, vol.33
, pp. 244-255
-
-
Lawlor, N.1
Khetan, S.2
Ucar, D.3
Stitzel, M.L.4
-
33
-
-
84907013152
-
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
-
PID: 25157153
-
Majithia AR, Flannick J, Shahinian P et al (2014) Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Proc Natl Acad Sci U S A 111:13127–13132
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 13127-13132
-
-
Majithia, A.R.1
Flannick, J.2
Shahinian, P.3
-
35
-
-
84897452599
-
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion
-
PID: 24603685
-
Dayeh T, Volkov P, Salo S et al (2014) Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion. PLoS Genet 10:e1004160
-
(2014)
PLoS Genet
, vol.10
-
-
Dayeh, T.1
Volkov, P.2
Salo, S.3
-
36
-
-
84870319843
-
Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes
-
PID: 23028138
-
Nitert MD, Dayeh T, Volkov P et al (2012) Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes. Diabetes 61:3322–3332
-
(2012)
Diabetes
, vol.61
, pp. 3322-3332
-
-
Nitert, M.D.1
Dayeh, T.2
Volkov, P.3
-
37
-
-
84906707442
-
Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes
-
PID: 24812430
-
Nilsson E, Jansson PA, Perfilyev A et al (2014) Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes. Diabetes 63:2962–2976
-
(2014)
Diabetes
, vol.63
, pp. 2962-2976
-
-
Nilsson, E.1
Jansson, P.A.2
Perfilyev, A.3
-
38
-
-
84969776770
-
Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort
-
PID: 27162351
-
Chen Z, Miao F, Paterson AD et al (2016) Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort. Proc Natl Acad Sci U S A 113:E3002–E3011
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E3002-E3011
-
-
Chen, Z.1
Miao, F.2
Paterson, A.D.3
-
39
-
-
85018522287
-
Role of DNA methylation in type 2 diabetes etiology: using genotype as a causal anchor
-
PID: 28246294
-
Elliott HR, Shihab HA, Lockett GA et al (2017) Role of DNA methylation in type 2 diabetes etiology: using genotype as a causal anchor. Diabetes 66:1713–1722
-
(2017)
Diabetes
, vol.66
, pp. 1713-1722
-
-
Elliott, H.R.1
Shihab, H.A.2
Lockett, G.A.3
-
40
-
-
85016157333
-
Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell
-
PID: 28332581
-
Ofori JK, Salunkhe VA, Bagge A et al (2017) Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell. Sci Rep 7:44986
-
(2017)
Sci Rep
, vol.7
, pp. 44986
-
-
Ofori, J.K.1
Salunkhe, V.A.2
Bagge, A.3
-
41
-
-
9144270691
-
A pancreatic islet-specific microRNA regulates insulin secretion
-
PID: 15538371
-
Poy MN, Eliasson L, Krutzfeldt J et al (2004) A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432:226–230
-
(2004)
Nature
, vol.432
, pp. 226-230
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
-
42
-
-
84973154959
-
Regulation of insulin resistance by multiple MiRNAs via targeting the GLUT4 signalling pathway
-
PID: 27165190
-
Zhou T, Meng X, Che H et al (2016) Regulation of insulin resistance by multiple MiRNAs via targeting the GLUT4 signalling pathway. Cell Physiol Biochem 38:2063–2078
-
(2016)
Cell Physiol Biochem
, vol.38
, pp. 2063-2078
-
-
Zhou, T.1
Meng, X.2
Che, H.3
-
43
-
-
79959845414
-
MicroRNAs 103 and 107 regulate insulin sensitivity
-
PID: 21654750
-
Trajkovski M, Hausser J, Soutschek J et al (2011) MicroRNAs 103 and 107 regulate insulin sensitivity. Nature 474:649–653
-
(2011)
Nature
, vol.474
, pp. 649-653
-
-
Trajkovski, M.1
Hausser, J.2
Soutschek, J.3
-
44
-
-
84959504301
-
βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function
-
PID: 26944677
-
Arnes L, Akerman I, Balderes DA, Ferrer J, Sussel L (2016) βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function. Genes Dev 30:502–507
-
(2016)
Genes Dev
, vol.30
, pp. 502-507
-
-
Arnes, L.1
Akerman, I.2
Balderes, D.A.3
Ferrer, J.4
Sussel, L.5
-
45
-
-
84957565613
-
Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice
-
PID: 26852333
-
Jalabert A, Vial G, Guay C et al (2016) Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice. Diabetologia 59:1049–1058
-
(2016)
Diabetologia
, vol.59
, pp. 1049-1058
-
-
Jalabert, A.1
Vial, G.2
Guay, C.3
-
46
-
-
84944355473
-
Physical exercise induces rapid release of small extracellular vesicles into the circulation
-
PID: 26142461
-
Fruhbeis C, Helmig S, Tug S, Simon P, Kramer-Albers EM (2015) Physical exercise induces rapid release of small extracellular vesicles into the circulation. J Extracell Vesicles 4:28239
-
(2015)
J Extracell Vesicles
, vol.4
, pp. 28239
-
-
Fruhbeis, C.1
Helmig, S.2
Tug, S.3
Simon, P.4
Kramer-Albers, E.M.5
-
47
-
-
85029668381
-
Adipose tissue macrophage-derived exosomal miRNAs can modulate in vivo and in vitro insulin sensitivity
-
PID: 28942920
-
Ying W, Riopel M, Bandyopadhyay G et al (2017) Adipose tissue macrophage-derived exosomal miRNAs can modulate in vivo and in vitro insulin sensitivity. Cell 171:372–384.e12
-
(2017)
Cell
, vol.171
, pp. 372-384.e12
-
-
Ying, W.1
Riopel, M.2
Bandyopadhyay, G.3
|