Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate in Vivo and in Vitro Insulin Sensitivity

Cell

Volumn 171, Issue 2, 2017, Pages 372-384.e12

  Ying, Wei ^a   Riopel, Matthew ^a   Bandyopadhyay, Gautam ^a   Dong, Yi ^b   Birmingham, Amanda ^b   Seo, Jong Bae ^a   Ofrecio, Jachelle M ^a   Wollam, Joshua ^a   Hernandez Carretero, Angelina ^a   Fu, Wenxian ^b   Li, Pingping ^c   Olefsky, Jerrold M ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

adipose tissue macrophages; exosomes; glucose intolerance; insulin resistance; miR 155; miRNA; obesity; PPAR

Indexed keywords

GLUCOSE; INSULIN; MICRORNA; MICRORNA 155; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; MIRN155 MICRORNA, MOUSE;

ADIPOSE TISSUE MACROPHAGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; EXOSOME; GENE OVEREXPRESSION; GENE TARGETING; GENETIC REGULATION; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HORMONAL REGULATION; HORMONE ACTION; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; MACROPHAGE; MALE; MOUSE; NONHUMAN; OBESITY; PARACRINE SIGNALING; PRIORITY JOURNAL; WILD TYPE; ADIPOCYTE; ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; LIVER; LIVER CELL; METABOLISM; MUSCLE CELL; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; CELLS, CULTURED; GLUCOSE; HEPATOCYTES; INSULIN RESISTANCE; LIVER; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; MUSCLE CELLS; MUSCLE, SKELETAL; SIGNAL TRANSDUCTION;

EID: 85029668381     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.08.035     Document Type: Article

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