-
1
-
-
0037237370
-
Glucose regulation and oxidative stress in healthy centenarians
-
M. Barbieri, M.R. Rizzo, D. Manzella, R. Grella, E. Ragno, M. Carbonella, A.M. Abbatecola, and G. Paolisso Glucose regulation and oxidative stress in healthy centenarians Exp. Gerontol. 38 2003 137 143
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 137-143
-
-
Barbieri, M.1
Rizzo, M.R.2
Manzella, D.3
Grella, R.4
Ragno, E.5
Carbonella, M.6
Abbatecola, A.M.7
Paolisso, G.8
-
2
-
-
84876077532
-
Metabolic characteristics of long-lived mice
-
A. Bartke, and R. Westbrook Metabolic characteristics of long-lived mice Front. Genet. 3 2012 288
-
(2012)
Front. Genet.
, vol.3
, pp. 288
-
-
Bartke, A.1
Westbrook, R.2
-
3
-
-
0037231580
-
Insulin-like growth factor 1 (IGF-1) and aging: Controversies and new insights
-
A. Bartke, V. Chandrashekar, F. Dominici, D. Turyn, B. Kinney, R. Steger, and J.J. Kopchick Insulin-like growth factor 1 (IGF-1) and aging: controversies and new insights Biogerontology 4 2003 1 8
-
(2003)
Biogerontology
, vol.4
, pp. 1-8
-
-
Bartke, A.1
Chandrashekar, V.2
Dominici, F.3
Turyn, D.4
Kinney, B.5
Steger, R.6
Kopchick, J.J.7
-
4
-
-
84863283393
-
Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice
-
P.K. Battiprolu, B. Hojayev, N. Jiang, Z.V. Wang, X. Luo, M. Iglewski, J.M. Shelton, R.D. Gerard, B.A. Rothermel, T.G. Gillette, and et al. Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice J. Clin. Invest. 122 2012 1109 1118
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1109-1118
-
-
Battiprolu, P.K.1
Hojayev, B.2
Jiang, N.3
Wang, Z.V.4
Luo, X.5
Iglewski, M.6
Shelton, J.M.7
Gerard, R.D.8
Rothermel, B.A.9
Gillette, T.G.10
-
5
-
-
33645982255
-
From mice to men: Insights into the insulin resistance syndromes
-
S.B. Biddinger, and C.R. Kahn From mice to men: insights into the insulin resistance syndromes Annu. Rev. Physiol. 68 2006 123 158
-
(2006)
Annu. Rev. Physiol.
, vol.68
, pp. 123-158
-
-
Biddinger, S.B.1
Kahn, C.R.2
-
6
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
M. Blüher, B.B. Kahn, and C.R. Kahn Extended longevity in mice lacking the insulin receptor in adipose tissue Science 299 2003 572 574
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Blüher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
7
-
-
0036724346
-
Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women
-
T.A. Buchanan, A.H. Xiang, R.K. Peters, S.L. Kjos, A. Marroquin, J. Goico, C. Ochoa, S. Tan, K. Berkowitz, H.N. Hodis, and S.P. Azen Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women Diabetes 51 2002 2796 2803
-
(2002)
Diabetes
, vol.51
, pp. 2796-2803
-
-
Buchanan, T.A.1
Xiang, A.H.2
Peters, R.K.3
Kjos, S.L.4
Marroquin, A.5
Goico, J.6
Ochoa, C.7
Tan, S.8
Berkowitz, K.9
Hodis, H.N.10
Azen, S.P.11
-
8
-
-
84864678390
-
High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction
-
A. Chalkiadaki, and L. Guarente High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction Cell Metab. 16 2012 180 188
-
(2012)
Cell Metab.
, vol.16
, pp. 180-188
-
-
Chalkiadaki, A.1
Guarente, L.2
-
9
-
-
53349143823
-
Metabolic consequences of pregnancy-associated plasma protein-A deficiency in mice: Exploring possible relationship to the longevity phenotype
-
C.A. Conover, M.A. Mason, J.A. Levine, and C.M. Novak Metabolic consequences of pregnancy-associated plasma protein-A deficiency in mice: exploring possible relationship to the longevity phenotype J. Endocrinol. 198 2008 599 605
-
(2008)
J. Endocrinol.
, vol.198
, pp. 599-605
-
-
Conover, C.A.1
Mason, M.A.2
Levine, J.A.3
Novak, C.M.4
-
10
-
-
0041419437
-
Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor i levels and increased life span
-
K.T. Coschigano, A.N. Holland, M.E. Riders, E.O. List, A. Flyvbjerg, and J.J. Kopchick Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span Endocrinology 144 2003 3799 3810
-
(2003)
Endocrinology
, vol.144
, pp. 3799-3810
-
-
Coschigano, K.T.1
Holland, A.N.2
Riders, M.E.3
List, E.O.4
Flyvbjerg, A.5
Kopchick, J.J.6
-
11
-
-
84873560029
-
Impairment of the proteasome is crucial for glucose-induced lifespan reduction in the mev-1 mutant of Caenorhabditis elegans
-
E. Fitzenberger, M. Boll, and U. Wenzel Impairment of the proteasome is crucial for glucose-induced lifespan reduction in the mev-1 mutant of Caenorhabditis elegans Biochim. Biophys. Acta 1832 2013 565 573
-
(2013)
Biochim. Biophys. Acta
, vol.1832
, pp. 565-573
-
-
Fitzenberger, E.1
Boll, M.2
Wenzel, U.3
-
12
-
-
79951938474
-
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
-
J. Guevara-Aguirre, P. Balasubramanian, M. Guevara-Aguirre, M. Wei, F. Madia, C.W. Cheng, D. Hwang, A. Martin-Montalvo, J. Saavedra, S. Ingles, and et al. Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans Sci. Transl. Med. 3 2011 70ra13
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 70ra13
-
-
Guevara-Aguirre, J.1
Balasubramanian, P.2
Guevara-Aguirre, M.3
Wei, M.4
Madia, F.5
Cheng, C.W.6
Hwang, D.7
Martin-Montalvo, A.8
Saavedra, J.9
Ingles, S.10
-
13
-
-
16844379373
-
Hyperglycemia, impaired glucose tolerance and elevated glycated hemoglobin levels in a long-lived mouse stock
-
J.M. Harper, S.J. Durkee, M. Smith-Wheelock, and R.A. Miller Hyperglycemia, impaired glucose tolerance and elevated glycated hemoglobin levels in a long-lived mouse stock Exp. Gerontol. 40 2005 303 314
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 303-314
-
-
Harper, J.M.1
Durkee, S.J.2
Smith-Wheelock, M.3
Miller, R.A.4
-
14
-
-
77954444618
-
Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction
-
J.M. Harper, J.E. Wilkinson, and R.A. Miller Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction FASEB J. 24 2010 2436 2442
-
(2010)
FASEB J.
, vol.24
, pp. 2436-2442
-
-
Harper, J.M.1
Wilkinson, J.E.2
Miller, R.A.3
-
15
-
-
84895825386
-
Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males
-
D.E. Harrison, R. Strong, D.B. Allison, B.N. Ames, C.M. Astle, H. Atamna, E. Fernandez, K. Flurkey, M.A. Javors, N.L. Nadon, and et al. Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males Aging Cell 13 2014 273 282
-
(2014)
Aging Cell
, vol.13
, pp. 273-282
-
-
Harrison, D.E.1
Strong, R.2
Allison, D.B.3
Ames, B.N.4
Astle, C.M.5
Atamna, H.6
Fernandez, E.7
Flurkey, K.8
Javors, M.A.9
Nadon, N.L.10
-
16
-
-
31344478502
-
Housing density does not influence the longevity effect of calorie restriction
-
Y. Ikeno, G.B. Hubbard, S. Lee, A. Richardson, R. Strong, V. Diaz, and J.F. Nelson Housing density does not influence the longevity effect of calorie restriction J. Gerontol. A Biol. Sci. Med. Sci. 60 2005 1510 1517
-
(2005)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.60
, pp. 1510-1517
-
-
Ikeno, Y.1
Hubbard, G.B.2
Lee, S.3
Richardson, A.4
Strong, R.5
Diaz, V.6
Nelson, J.F.7
-
17
-
-
79955517215
-
Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis
-
J.L. Jewell, E. Oh, L. Ramalingam, M.A. Kalwat, V.S. Tagliabracci, L. Tackett, J.S. Elmendorf, and D.C. Thurmond Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis J. Cell Biol. 193 2011 185 199
-
(2011)
J. Cell Biol.
, vol.193
, pp. 185-199
-
-
Jewell, J.L.1
Oh, E.2
Ramalingam, L.3
Kalwat, M.A.4
Tagliabracci, V.S.5
Tackett, L.6
Elmendorf, J.S.7
Thurmond, D.C.8
-
18
-
-
84879117381
-
The GH/IGF-1 axis in ageing and longevity
-
R.K. Junnila, E.O. List, D.E. Berryman, J.W. Murrey, and J.J. Kopchick The GH/IGF-1 axis in ageing and longevity Nat. Rev. Endocrinol. 9 2013 366 376
-
(2013)
Nat. Rev. Endocrinol.
, vol.9
, pp. 366-376
-
-
Junnila, R.K.1
List, E.O.2
Berryman, D.E.3
Murrey, J.W.4
Kopchick, J.J.5
-
19
-
-
43149125186
-
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility
-
M.P. Keller, Y. Choi, P. Wang, D.B. Davis, M.E. Rabaglia, A.T. Oler, D.S. Stapleton, C. Argmann, K.L. Schueler, S. Edwards, and et al. A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility Genome Res. 18 2008 706 716
-
(2008)
Genome Res.
, vol.18
, pp. 706-716
-
-
Keller, M.P.1
Choi, Y.2
Wang, P.3
Davis, D.B.4
Rabaglia, M.E.5
Oler, A.T.6
Stapleton, D.S.7
Argmann, C.8
Schueler, K.L.9
Edwards, S.10
-
20
-
-
27544460718
-
Extended longevity and insulin signaling in adipose tissue
-
N. Klöting, and M. Blüher Extended longevity and insulin signaling in adipose tissue Exp. Gerontol. 40 2005 878 883
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 878-883
-
-
Klöting, N.1
Blüher, M.2
-
21
-
-
38749125151
-
Oxidative stress contributes to aging by enhancing pancreatic angiogenesis and insulin signaling
-
G. Laurent, F. Solari, B. Mateescu, M. Karaca, J. Castel, B. Bourachot, C. Magnan, M. Billaud, and F. Mechta-Grigoriou Oxidative stress contributes to aging by enhancing pancreatic angiogenesis and insulin signaling Cell Metab. 7 2008 113 124
-
(2008)
Cell Metab.
, vol.7
, pp. 113-124
-
-
Laurent, G.1
Solari, F.2
Mateescu, B.3
Karaca, M.4
Castel, J.5
Bourachot, B.6
Magnan, C.7
Billaud, M.8
Mechta-Grigoriou, F.9
-
22
-
-
78649497300
-
Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance
-
H.Y. Lee, C.S. Choi, A.L. Birkenfeld, T.C. Alves, F.R. Jornayvaz, M.J. Jurczak, D. Zhang, D.K. Woo, G.S. Shadel, W. Ladiges, and et al. Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance Cell Metab. 12 2010 668 674
-
(2010)
Cell Metab.
, vol.12
, pp. 668-674
-
-
Lee, H.Y.1
Choi, C.S.2
Birkenfeld, A.L.3
Alves, T.C.4
Jornayvaz, F.R.5
Jurczak, M.J.6
Zhang, D.7
Woo, D.K.8
Shadel, G.S.9
Ladiges, W.10
-
23
-
-
7444234167
-
Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function
-
Y. Li, W. Xu, Z. Liao, B. Yao, X. Chen, Z. Huang, G. Hu, and J. Weng Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function Diabetes Care 27 2004 2597 2602
-
(2004)
Diabetes Care
, vol.27
, pp. 2597-2602
-
-
Li, Y.1
Xu, W.2
Liao, Z.3
Yao, B.4
Chen, X.5
Huang, Z.6
Hu, G.7
Weng, J.8
-
24
-
-
79958243025
-
Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse
-
E.O. List, L. Sackmann-Sala, D.E. Berryman, K. Funk, B. Kelder, E.S. Gosney, S. Okada, J. Ding, D. Cruz-Topete, and J.J. Kopchick Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse Endocr. Rev. 32 2011 356 386
-
(2011)
Endocr. Rev.
, vol.32
, pp. 356-386
-
-
List, E.O.1
Sackmann-Sala, L.2
Berryman, D.E.3
Funk, K.4
Kelder, B.5
Gosney, E.S.6
Okada, S.7
Ding, J.8
Cruz-Topete, D.9
Kopchick, J.J.10
-
25
-
-
84901403995
-
Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
-
R.A. Miller, D.E. Harrison, C.M. Astle, E. Fernandez, K. Flurkey, M. Han, M.A. Javors, X. Li, N.L. Nadon, J.F. Nelson, and et al. Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction Aging Cell 13 2014 468 477
-
(2014)
Aging Cell
, vol.13
, pp. 468-477
-
-
Miller, R.A.1
Harrison, D.E.2
Astle, C.M.3
Fernandez, E.4
Flurkey, K.5
Han, M.6
Javors, M.A.7
Li, X.8
Nadon, N.L.9
Nelson, J.F.10
-
26
-
-
84895925833
-
The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet
-
S.J. Mitchell, A. Martin-Montalvo, E.M. Mercken, H.H. Palacios, T.M. Ward, G. Abulwerdi, R.K. Minor, G.P. Vlasuk, J.L. Ellis, D.A. Sinclair, and et al. The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet Cell Rep. 6 2014 836 843
-
(2014)
Cell Rep.
, vol.6
, pp. 836-843
-
-
Mitchell, S.J.1
Martin-Montalvo, A.2
Mercken, E.M.3
Palacios, H.H.4
Ward, T.M.5
Abulwerdi, G.6
Minor, R.K.7
Vlasuk, G.P.8
Ellis, J.L.9
Sinclair, D.A.10
-
27
-
-
84880517634
-
The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
-
L. Mouchiroud, R.H. Houtkooper, N. Moullan, E. Katsyuba, D. Ryu, C. Cantó, A. Mottis, Y.S. Jo, M. Viswanathan, K. Schoonjans, and et al. The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling Cell 154 2013 430 441
-
(2013)
Cell
, vol.154
, pp. 430-441
-
-
Mouchiroud, L.1
Houtkooper, R.H.2
Moullan, N.3
Katsyuba, E.4
Ryu, D.5
Cantó, C.6
Mottis, A.7
Jo, Y.S.8
Viswanathan, M.9
Schoonjans, K.10
-
28
-
-
25144454432
-
Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice
-
K.A. Moynihan, A.A. Grimm, M.M. Plueger, E. Bernal-Mizrachi, E. Ford, C. Cras-Méneur, M.A. Permutt, and S. Imai Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice Cell Metab. 2 2005 105 117
-
(2005)
Cell Metab.
, vol.2
, pp. 105-117
-
-
Moynihan, K.A.1
Grimm, A.A.2
Plueger, M.M.3
Bernal-Mizrachi, E.4
Ford, E.5
Cras-Méneur, C.6
Permutt, M.A.7
Imai, S.8
-
29
-
-
84899914501
-
Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus
-
E. Oh, N.D. Stull, R.G. Mirmira, and D.C. Thurmond Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus J. Clin. Endocrinol. Metab. 99 2014 E866 E870
-
(2014)
J. Clin. Endocrinol. Metab.
, vol.99
, pp. E866-E870
-
-
Oh, E.1
Stull, N.D.2
Mirmira, R.G.3
Thurmond, D.C.4
-
30
-
-
0029898677
-
Glucose tolerance and insulin action in healty centenarians
-
G. Paolisso, A. Gambardella, S. Ammendola, A. D'Amore, V. Balbi, M. Varricchio, and F. D'Onofrio Glucose tolerance and insulin action in healty centenarians Am. J. Physiol. 270 1996 E890 E894
-
(1996)
Am. J. Physiol.
, vol.270
, pp. E890-E894
-
-
Paolisso, G.1
Gambardella, A.2
Ammendola, S.3
D'Amore, A.4
Balbi, V.5
Varricchio, M.6
D'Onofrio, F.7
-
31
-
-
38349112898
-
Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice
-
K.M. Ramsey, K.F. Mills, A. Satoh, and S. Imai Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice Aging Cell 7 2008 78 88
-
(2008)
Aging Cell
, vol.7
, pp. 78-88
-
-
Ramsey, K.M.1
Mills, K.F.2
Satoh, A.3
Imai, S.4
-
32
-
-
70349323414
-
Lipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5′-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside
-
D.A. Rivas, B.B. Yaspelkis 3rd, J.A. Hawley, and S.J. Lessard Lipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5′-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside J. Endocrinol. 202 2009 441 451
-
(2009)
J. Endocrinol.
, vol.202
, pp. 441-451
-
-
Rivas, D.A.1
Yaspelkis, B.B.2
Hawley, J.A.3
Lessard, S.J.4
-
33
-
-
77949396024
-
Favorable glucose tolerance and lower prevalence of metabolic syndrome in offspring without diabetes mellitus of nonagenarian siblings: The Leiden longevity study
-
M.P. Rozing, R.G. Westendorp, A.J. de Craen, M. Frölich, M.C. de Goeij, B.T. Heijmans, M. Beekman, C.A. Wijsman, S.P. Mooijaart, G.J. Blauw, et al. Leiden Longevity Study Group Favorable glucose tolerance and lower prevalence of metabolic syndrome in offspring without diabetes mellitus of nonagenarian siblings: the Leiden longevity study J. Am. Geriatr. Soc. 58 2010 564 569
-
(2010)
J. Am. Geriatr. Soc.
, vol.58
, pp. 564-569
-
-
Rozing, M.P.1
Westendorp, R.G.2
De Craen, A.J.3
Frölich, M.4
De Goeij, M.C.5
Heijmans, B.T.6
Beekman, M.7
Wijsman, C.A.8
Mooijaart, S.P.9
Blauw, G.J.10
-
34
-
-
84901709439
-
Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis
-
M. Sadagurski, T. Landeryou, M. Blandino-Rosano, G. Cady, L. Elghazi, D. Meister, L. See, A. Bartke, E. Bernal-Mizrachi, and R.A. Miller Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis Am. J. Physiol. Endocrinol. Metab. 306 2014 E1305 E1314
-
(2014)
Am. J. Physiol. Endocrinol. Metab.
, vol.306
, pp. E1305-E1314
-
-
Sadagurski, M.1
Landeryou, T.2
Blandino-Rosano, M.3
Cady, G.4
Elghazi, L.5
Meister, D.6
See, L.7
Bartke, A.8
Bernal-Mizrachi, E.9
Miller, R.A.10
-
35
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
A.R. Saltiel, and C.R. Kahn Insulin signalling and the regulation of glucose and lipid metabolism Nature 414 2001 799 806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
36
-
-
84883476818
-
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH
-
A. Satoh, C.S. Brace, N. Rensing, P. Cliften, D.F. Wozniak, E.D. Herzog, K.A. Yamada, and S. Imai Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH Cell Metab. 18 2013 416 430
-
(2013)
Cell Metab.
, vol.18
, pp. 416-430
-
-
Satoh, A.1
Brace, C.S.2
Rensing, N.3
Cliften, P.4
Wozniak, D.F.5
Herzog, E.D.6
Yamada, K.A.7
Imai, S.8
-
37
-
-
0029670584
-
Efficient control of gene expression by single step integration of the tetracycline system in transgenic mice
-
N. Schultze, Y. Burki, Y. Lang, U. Certa, and H. Bluethmann Efficient control of gene expression by single step integration of the tetracycline system in transgenic mice Nat. Biotechnol. 14 1996 499 503
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 499-503
-
-
Schultze, N.1
Burki, Y.2
Lang, Y.3
Certa, U.4
Bluethmann, H.5
-
38
-
-
70349669095
-
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
-
C. Selman, J.M. Tullet, D. Wieser, E. Irvine, S.J. Lingard, A.I. Choudhury, M. Claret, H. Al-Qassab, D. Carmignac, F. Ramadani, and et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span Science 326 2009 140 144
-
(2009)
Science
, vol.326
, pp. 140-144
-
-
Selman, C.1
Tullet, J.M.2
Wieser, D.3
Irvine, E.4
Lingard, S.J.5
Choudhury, A.I.6
Claret, M.7
Al-Qassab, H.8
Carmignac, D.9
Ramadani, F.10
-
39
-
-
29444444591
-
Syntaxin 4 facilitates biphasic glucose-stimulated insulin secretion from pancreatic beta-cells
-
B.A. Spurlin, and D.C. Thurmond Syntaxin 4 facilitates biphasic glucose-stimulated insulin secretion from pancreatic beta-cells Mol. Endocrinol. 20 2006 183 193
-
(2006)
Mol. Endocrinol.
, vol.20
, pp. 183-193
-
-
Spurlin, B.A.1
Thurmond, D.C.2
-
40
-
-
4344673217
-
Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle
-
B.A. Spurlin, S.Y. Park, A.K. Nevins, J.K. Kim, and D.C. Thurmond Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle Diabetes 53 2004 2223 2231
-
(2004)
Diabetes
, vol.53
, pp. 2223-2231
-
-
Spurlin, B.A.1
Park, S.Y.2
Nevins, A.K.3
Kim, J.K.4
Thurmond, D.C.5
-
41
-
-
84863565284
-
Macrophage migration inhibitory factor deficiency protects pancreatic islets from cytokine-induced apoptosis in vitro
-
I. Stojanovic, T. Saksida, I. Nikolic, F. Nicoletti, and S. Stosic-Grujicic Macrophage migration inhibitory factor deficiency protects pancreatic islets from cytokine-induced apoptosis in vitro Clin. Exp. Immunol. 169 2012 156 163
-
(2012)
Clin. Exp. Immunol.
, vol.169
, pp. 156-163
-
-
Stojanovic, I.1
Saksida, T.2
Nikolic, I.3
Nicoletti, F.4
Stosic-Grujicic, S.5
-
42
-
-
42949172969
-
Macrophage migration inhibitory factor (MIF) is necessary for progression of autoimmune diabetes mellitus
-
S. Stosic-Grujicic, I. Stojanovic, D. Maksimovic-Ivanic, M. Momcilovic, D. Popadic, L. Harhaji, D. Miljkovic, C. Metz, K. Mangano, G. Papaccio, and et al. Macrophage migration inhibitory factor (MIF) is necessary for progression of autoimmune diabetes mellitus J. Cell. Physiol. 215 2008 665 675
-
(2008)
J. Cell. Physiol.
, vol.215
, pp. 665-675
-
-
Stosic-Grujicic, S.1
Stojanovic, I.2
Maksimovic-Ivanic, D.3
Momcilovic, M.4
Popadic, D.5
Harhaji, L.6
Miljkovic, D.7
Metz, C.8
Mangano, K.9
Papaccio, G.10
-
43
-
-
34547097247
-
Brain IRS2 signaling coordinates life span and nutrient homeostasis
-
A. Taguchi, L.M. Wartschow, and M.F. White Brain IRS2 signaling coordinates life span and nutrient homeostasis Science 317 2007 369 372
-
(2007)
Science
, vol.317
, pp. 369-372
-
-
Taguchi, A.1
Wartschow, L.M.2
White, M.F.3
-
44
-
-
84940647013
-
Potential site effects and transgene expression discrepancies in mouse lifespan studies
-
this issue
-
D.C. Thurmond, E. Oh, and R.A. Miller Potential site effects and transgene expression discrepancies in mouse lifespan studies Cell Metab. 22 2015 346 347 this issue
-
(2015)
Cell Metab.
, vol.22
, pp. 346-347
-
-
Thurmond, D.C.1
Oh, E.2
Miller, R.A.3
-
45
-
-
84881660662
-
Age-related changes of forkhead transcription factor FOXO1 in the liver of senescence-accelerated mouse SAMP8
-
K. Tomobe, T. Shinozuka, T. Kawashima, Y. Kawashima-Ohya, and Y. Nomura Age-related changes of forkhead transcription factor FOXO1 in the liver of senescence-accelerated mouse SAMP8 Arch. Gerontol. Geriatr. 57 2013 417 422
-
(2013)
Arch. Gerontol. Geriatr.
, vol.57
, pp. 417-422
-
-
Tomobe, K.1
Shinozuka, T.2
Kawashima, T.3
Kawashima-Ohya, Y.4
Nomura, Y.5
-
46
-
-
4544220704
-
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
-
S.H. Um, F. Frigerio, M. Watanabe, F. Picard, M. Joaquin, M. Sticker, S. Fumagalli, P.R. Allegrini, S.C. Kozma, J. Auwerx, and G. Thomas Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity Nature 431 2004 200 205
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
Sticker, M.6
Fumagalli, S.7
Allegrini, P.R.8
Kozma, S.C.9
Auwerx, J.10
Thomas, G.11
-
47
-
-
22144477243
-
Reduced insulin/IGF-1 signalling and human longevity
-
D. van Heemst, M. Beekman, S.P. Mooijaart, B.T. Heijmans, B.W. Brandt, B.J. Zwaan, P.E. Slagboom, and R.G. Westendorp Reduced insulin/IGF-1 signalling and human longevity Aging Cell 4 2005 79 85
-
(2005)
Aging Cell
, vol.4
, pp. 79-85
-
-
Van Heemst, D.1
Beekman, M.2
Mooijaart, S.P.3
Heijmans, B.T.4
Brandt, B.W.5
Zwaan, B.J.6
Slagboom, P.E.7
Westendorp, R.G.8
-
48
-
-
84891860991
-
The many faces of sirtuins: Coupling of NAD metabolism, sirtuins and lifespan
-
E. Verdin The many faces of sirtuins: Coupling of NAD metabolism, sirtuins and lifespan Nat. Med. 20 2014 25 27
-
(2014)
Nat. Med.
, vol.20
, pp. 25-27
-
-
Verdin, E.1
-
49
-
-
67949111187
-
MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease
-
L. Verschuren, T. Kooistra, J. Bernhagen, P.J. Voshol, D.M. Ouwens, M. van Erk, J. de Vries-van der Weij, L. Leng, J.H. van Bockel, K.W. van Dijk, and et al. MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease Circ. Res. 105 2009 99 107
-
(2009)
Circ. Res.
, vol.105
, pp. 99-107
-
-
Verschuren, L.1
Kooistra, T.2
Bernhagen, J.3
Voshol, P.J.4
Ouwens, D.M.5
Van Erk, M.6
De Vries-Van Der Weij, J.7
Leng, L.8
Van Bockel, J.H.9
Van Dijk, K.W.10
-
50
-
-
82355184464
-
Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo
-
Z. Wang, E. Oh, D.W. Clapp, J. Chernoff, and D.C. Thurmond Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo J. Biol. Chem. 286 2011 41359 41367
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 41359-41367
-
-
Wang, Z.1
Oh, E.2
Clapp, D.W.3
Chernoff, J.4
Thurmond, D.C.5
-
51
-
-
78651269359
-
Familial longevity is marked by enhanced insulin sensitivity
-
C.A. Wijsman, M.P. Rozing, T.C. Streefland, S. le Cessie, S.P. Mooijaart, P.E. Slagboom, R.G. Westendorp, H. Pijl, D. van Heemst Leiden Longevity Study group Familial longevity is marked by enhanced insulin sensitivity Aging Cell 10 2011 114 121
-
(2011)
Aging Cell
, vol.10
, pp. 114-121
-
-
Wijsman, C.A.1
Rozing, M.P.2
Streefland, T.C.3
Le Cessie, S.4
Mooijaart, S.P.5
Slagboom, P.E.6
Westendorp, R.G.7
Pijl, H.8
Van Heemst, D.9
-
52
-
-
84892530622
-
Longevity effect of IGF-1R(+/-) mutation depends on genetic background-specific receptor activation
-
J. Xu, G. Gontier, Z. Chaker, P. Lacube, J. Dupont, and M. Holzenberger Longevity effect of IGF-1R(+/-) mutation depends on genetic background-specific receptor activation Aging Cell 13 2014 19 28
-
(2014)
Aging Cell
, vol.13
, pp. 19-28
-
-
Xu, J.1
Gontier, G.2
Chaker, Z.3
Lacube, P.4
Dupont, J.5
Holzenberger, M.6
-
53
-
-
0035000661
-
Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance
-
C. Yang, K.J. Coker, J.K. Kim, S. Mora, D.C. Thurmond, A.C. Davis, B. Yang, R.A. Williamson, G.I. Shulman, and J.E. Pessin Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance J. Clin. Invest. 107 2001 1311 1318
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1311-1318
-
-
Yang, C.1
Coker, K.J.2
Kim, J.K.3
Mora, S.4
Thurmond, D.C.5
Davis, A.C.6
Yang, B.7
Williamson, R.A.8
Shulman, G.I.9
Pessin, J.E.10
-
54
-
-
24744444176
-
Activated IGF-1R inhibits hyperglycemia-induced DNA damage and promotes DNA repair by homologous recombination
-
S. Yang, J. Chintapalli, L. Sodagum, S. Baskin, A. Malhotra, K. Reiss, and L.G. Meggs Activated IGF-1R inhibits hyperglycemia-induced DNA damage and promotes DNA repair by homologous recombination Am. J. Physiol. Renal Physiol. 289 2005 F1144 F1152
-
(2005)
Am. J. Physiol. Renal Physiol.
, vol.289
, pp. F1144-F1152
-
-
Yang, S.1
Chintapalli, J.2
Sodagum, L.3
Baskin, S.4
Malhotra, A.5
Reiss, K.6
Meggs, L.G.7
-
55
-
-
0036679129
-
Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice
-
V.K. Yechoor, M.E. Patti, R. Saccone, and C.R. Kahn Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice Proc. Natl. Acad. Sci. USA 99 2002 10587 10592
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10587-10592
-
-
Yechoor, V.K.1
Patti, M.E.2
Saccone, R.3
Kahn, C.R.4
-
56
-
-
0031846992
-
Insulin-dependent protein trafficking in skeletal muscle cells
-
M. Zhou, L. Sevilla, G. Vallega, P. Chen, M. Palacin, A. Zorzano, P.F. Pilch, and K.V. Kandror Insulin-dependent protein trafficking in skeletal muscle cells Am. J. Physiol. 275 1998 E187 E196
-
(1998)
Am. J. Physiol.
, vol.275
, pp. E187-E196
-
-
Zhou, M.1
Sevilla, L.2
Vallega, G.3
Chen, P.4
Palacin, M.5
Zorzano, A.6
Pilch, P.F.7
Kandror, K.V.8
|