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Volumn 12, Issue 6, 2018, Pages

Protein N-Glycosylation in Cardiovascular Diseases and Related Risk Factors

Author keywords

Atherosclerosis; Biomarker; Cardiovascular disease; N Glycosylation; Risk factors

Indexed keywords

C REACTIVE PROTEIN; GLYCAN; GLYCOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; IMMUNOGLOBULIN G; LOW DENSITY LIPOPROTEIN; N ACETYLGLUCOSAMINE; OLIGOSACCHARIDE; PROTEOME; SIALIC ACID; VERY LOW DENSITY LIPOPROTEIN;

EID: 85046797467     PISSN: 19329520     EISSN: 19329563     Source Type: Journal    
DOI: 10.1007/s12170-018-0579-4     Document Type: Review
Times cited : (19)

References (164)
  • 1
    • 84994158650 scopus 로고    scopus 로고
    • Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015
    • Wang H, Naghavi M, Allen C, Barber R, Bhutta ZA, Carter C, et al. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388:1459–544.
    • (2016) Lancet , vol.388 , pp. 1459-1544
    • Wang, H.1    Naghavi, M.2    Allen, C.3    Barber, R.4    Bhutta, Z.A.5    Carter, C.6
  • 4
    • 84935064641 scopus 로고    scopus 로고
    • Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease
    • COI: 1:CAS:528:DC%2BC2sXhs1KjtbnN, PID: 25862763
    • Gajjala PR, Fliser D, Speer T, Jankowski V, Jankowski J. Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease. Nephrol Dial Transplant. 2015;30:1814–24.
    • (2015) Nephrol Dial Transplant , vol.30 , pp. 1814-1824
    • Gajjala, P.R.1    Fliser, D.2    Speer, T.3    Jankowski, V.4    Jankowski, J.5
  • 5
    • 84922080261 scopus 로고    scopus 로고
    • Glycosyltransferases, glycosylation and atherosclerosis
    • COI: 1:CAS:528:DC%2BC2cXhslahtbjJ, PID: 25294497
    • Pu Q, Yu C. Glycosyltransferases, glycosylation and atherosclerosis. Glycoconj J. 2014;31:605–11.
    • (2014) Glycoconj J , vol.31 , pp. 605-611
    • Pu, Q.1    Yu, C.2
  • 6
    • 77955141846 scopus 로고    scopus 로고
    • O-GlcNAc signaling in the cardiovascular system
    • COI: 1:CAS:528:DC%2BC3cXpt1Kqsrw%3D, PID: 20651294
    • Ngoh GA, Facundo HT, Zafir A, Jones SP. O-GlcNAc signaling in the cardiovascular system. Circ Res. 2010;107:171–85.
    • (2010) Circ Res , vol.107 , pp. 171-185
    • Ngoh, G.A.1    Facundo, H.T.2    Zafir, A.3    Jones, S.P.4
  • 7
  • 8
    • 33745381312 scopus 로고    scopus 로고
    • Genetic defects in the human glycome
    • COI: 1:CAS:528:DC%2BD28XlvVGltL4%3D, PID: 16755287
    • Freeze HH. Genetic defects in the human glycome. Nat Rev Genet. 2006;7:537–51.
    • (2006) Nat Rev Genet , vol.7 , pp. 537-551
    • Freeze, H.H.1
  • 9
    • 84973652541 scopus 로고    scopus 로고
    • Mechanisms of disease: the human N-glycome
    • COI: 1:CAS:528:DC%2BC2MXhslWrsbnK, PID: 26500099
    • Lauc G, Pezer M, Rudan I, Campbell H. Mechanisms of disease: the human N-glycome. Biochim Biophys Acta. 2016;1860:1574–82.
    • (2016) Biochim Biophys Acta , vol.1860 , pp. 1574-1582
    • Lauc, G.1    Pezer, M.2    Rudan, I.3    Campbell, H.4
  • 10
    • 85045064232 scopus 로고    scopus 로고
    • Kosicek M, Gudelj I, Horvatic A, Jovic T, Vuckovic F, Lauc G, et al. N-glycome of the lysosomal glycocalyx is altered in Niemann-Pick type C disease model cellsAmerican Society for Biochemistry and Molecular Biology; 2018;mcp.RA117.000129
    • Kosicek M, Gudelj I, Horvatic A, Jovic T, Vuckovic F, Lauc G, et al. N-glycome of the lysosomal glycocalyx is altered in Niemann-Pick type C disease model cells. Mol Cell Proteomics. American Society for Biochemistry and Molecular Biology; 2018;mcp.RA117.000129.
    • Mol Cell Proteomics
  • 13
    • 84946023390 scopus 로고    scopus 로고
    • Systemic lupus erythematosus associates with the decreased immunosuppressive potential of the IgG glycome. Arthritis Rheumatol (Hoboken
    • Vučković F, Krištić J, Gudelj I, Teruel Artacho M, Keser T, Pezer M, et al. Systemic lupus erythematosus associates with the decreased immunosuppressive potential of the IgG glycome. Arthritis Rheumatol (Hoboken, NJ) 2015;67:2978–2989.
    • (2015) NJ) , vol.67 , pp. 2978-2989
    • Vučković, F.1    Krištić, J.2    Gudelj, I.3    Teruel Artacho, M.4    Keser, T.5    Pezer, M.6
  • 14
    • 85046767136 scopus 로고    scopus 로고
    • • Barrios C, Zierer J, Gudelj I, Stambuk J, Ugrina I, Rodriguez E, et al. Glycosylation profile of IgG in moderate kidney dysfunction. J Am Soc Nephrol. 2015;1–9. A. Important
    • • Barrios C, Zierer J, Gudelj I, Stambuk J, Ugrina I, Rodriguez E, et al. Glycosylation profile of IgG in moderate kidney dysfunction. J Am Soc Nephrol. 2015;1–9. A. Important: this paper shows the association of IgG N -glycome alterations with kidney disfunction.
    • This paper shows the association of IgG N -glycome alterations with kidney disfunction
  • 15
    • 85055862281 scopus 로고    scopus 로고
    • • Gudelj I, Salo PP, Trbojević-Akmačić I, Albers M, Primorac D, Perola M, et al. Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up. Biochim Biophys Acta - Mol Basis Dis. 2018. Important
    • • Gudelj I, Salo PP, Trbojević-Akmačić I, Albers M, Primorac D, Perola M, et al. Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up. Biochim Biophys Acta - Mol Basis Dis. 2018. Important: in this study, the authors found that N -glycosylation changes can precede future diagnosis of a disease for more than 10 years.
    • In this study, the authors found that N -glycosylation changes can precede future diagnosis of a disease for more than 10 years
  • 16
    • 84973621797 scopus 로고    scopus 로고
    • Precision medicine that transcends genomics: glycans as integrators of genes and environment
    • COI: 1:CAS:528:DC%2BC28XnsV2gs7k%3D
    • Lauc G. Precision medicine that transcends genomics: glycans as integrators of genes and environment. Biochim Biophys Acta - Gen Subj. 2016;1860:1571–3.
    • (2016) Biochim Biophys Acta - Gen Subj. , vol.1860 , pp. 1571-1573
    • Lauc, G.1
  • 17
    • 84862728161 scopus 로고    scopus 로고
    • Vertebrate protein glycosylation: diversity, synthesis and function
    • COI: 1:CAS:528:DC%2BC38XovFyktLs%3D, PID: 22722607
    • Moremen KW, Tiemeyer M, Nairn AV. Vertebrate protein glycosylation: diversity, synthesis and function. Nat Rev Mol Cell Biol. 2012;13:448–62.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 448-462
    • Moremen, K.W.1    Tiemeyer, M.2    Nairn, A.V.3
  • 18
    • 20844437106 scopus 로고    scopus 로고
    • Glycans in cancer and inflammation—potential for therapeutics and diagnostics
    • COI: 1:CAS:528:DC%2BD2MXks12ktrs%3D, PID: 15931257
    • Dube DH, Bertozzi CR. Glycans in cancer and inflammation—potential for therapeutics and diagnostics. Nat Rev Drug Discov. 2005;4:477–88.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 477-488
    • Dube, D.H.1    Bertozzi, C.R.2
  • 19
    • 84865365078 scopus 로고    scopus 로고
    • Insights into complexity of congenital disorders of glycosylation
    • COI: 1:CAS:528:DC%2BC38XhsVens7jK
    • Goreta SS, Dabelic S, Dumic J. Insights into complexity of congenital disorders of glycosylation. Biochem Med (Zagreb). 2012;22:156–70.
    • (2012) Biochem Med (Zagreb) , vol.22 , pp. 156-170
    • Goreta, S.S.1    Dabelic, S.2    Dumic, J.3
  • 21
    • 85025111840 scopus 로고    scopus 로고
    • Cardiac complications of congenital disorders of glycosylation (CDG): a systematic review of the literature
    • COI: 1:CAS:528:DC%2BC2sXhtF2qt7%2FE, PID: 28726068
    • Marques-da-Silva D, Francisco R, Webster D, dos Reis Ferreira V, Jaeken J, Pulinilkunnil T. Cardiac complications of congenital disorders of glycosylation (CDG): a systematic review of the literature. J Inherit Metab Dis. 2017;40:657–72.
    • (2017) J Inherit Metab Dis , vol.40 , pp. 657-672
    • Marques-da-Silva, D.1    Francisco, R.2    Webster, D.3    dos Reis Ferreira, V.4    Jaeken, J.5    Pulinilkunnil, T.6
  • 22
    • 0033017374 scopus 로고    scopus 로고
    • Enteroviral protease 2A cleaves dystrophin: evidence of cytoskeletal disruption in an acquired cardiomyopathy
    • COI: 1:CAS:528:DyaK1MXhsVSksbY%3D, PID: 10086389
    • Badorff C, Lee GH, Lamphear BJ, Martone ME, Campbell KP, Rhoads RE, et al. Enteroviral protease 2A cleaves dystrophin: evidence of cytoskeletal disruption in an acquired cardiomyopathy. Nat Med. 1999;5:320–6.
    • (1999) Nat Med , vol.5 , pp. 320-326
    • Badorff, C.1    Lee, G.H.2    Lamphear, B.J.3    Martone, M.E.4    Campbell, K.P.5    Rhoads, R.E.6    Knowlton, K.U.7
  • 23
    • 0031471956 scopus 로고    scopus 로고
    • Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, delta-sarcoglycan, in hamster: an animal model of disrupted dystrophin-associated glycoprotein complex
    • COI: 1:CAS:528:DyaK2sXotVart7c%3D, PID: 9391120
    • Sakamoto A, Ono K, Abe M, Jasmin G, Eki T, Murakami Y, et al. Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, delta-sarcoglycan, in hamster: an animal model of disrupted dystrophin-associated glycoprotein complex. Proc Natl Acad Sci U S A. 1997;94:13873–8.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13873-13878
    • Sakamoto, A.1    Ono, K.2    Abe, M.3    Jasmin, G.4    Eki, T.5    Murakami, Y.6    Masaki, T.7    Toyo-oka, T.8    Hanaoka, F.9
  • 25
    • 0036392644 scopus 로고    scopus 로고
    • Severe transient myocardial ischaemia caused by hypertrophic cardiomyopathy in a patient with congenital disorder of glycosylation type Ia
    • PID: 12297897
    • Marquardt T, Hülskamp G, Gehrmann J, Debus V, Harms E, Kehl H. Severe transient myocardial ischaemia caused by hypertrophic cardiomyopathy in a patient with congenital disorder of glycosylation type Ia. Eur J Pediatr. 2002;161:524–7.
    • (2002) Eur J Pediatr , vol.161 , pp. 524-527
    • Marquardt, T.1    Hülskamp, G.2    Gehrmann, J.3    Debus, V.4    Harms, E.5    Kehl, H.6
  • 27
    • 0035165830 scopus 로고    scopus 로고
    • Discontinuation of fucose therapy in LADII causes rapid loss of selectin ligands and rise of leukocyte counts
    • PID: 11133780
    • Lühn K, Marquardt T, Harms E, Vestweber D. Discontinuation of fucose therapy in LADII causes rapid loss of selectin ligands and rise of leukocyte counts. Blood. 2001;97:330–2.
    • (2001) Blood , vol.97 , pp. 330-332
    • Lühn, K.1    Marquardt, T.2    Harms, E.3    Vestweber, D.4
  • 28
    • 0032763425 scopus 로고    scopus 로고
    • Correction of leukocyte adhesion deficiency type II with oral fucose
    • COI: 1:CAS:528:DyaK1MXnvFOjs7Y%3D, PID: 10590041
    • Marquardt T, Lühn K, Srikrishna G, Freeze HH, Harms E, Vestweber D. Correction of leukocyte adhesion deficiency type II with oral fucose. Blood. 1999;94:3976–85.
    • (1999) Blood , vol.94 , pp. 3976-3985
    • Marquardt, T.1    Lühn, K.2    Srikrishna, G.3    Freeze, H.H.4    Harms, E.5    Vestweber, D.6
  • 29
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • COI: 1:CAS:528:DC%2BD38XpsFygtb8%3D, PID: 12490960
    • Libby P. Inflammation in atherosclerosis. Nature. 2002;420:868–74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 30
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis and coronary artery disease
    • COI: 1:CAS:528:DC%2BD2MXjsFCltrc%3D, PID: 15843671
    • Hansson GK. Inflammation, atherosclerosis and coronary artery disease. N Engl J Med. 2005;352:1685–95.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 31
    • 77955130598 scopus 로고    scopus 로고
    • The role of monocytes in atherosclerotic coronary artery disease
    • COI: 1:CAS:528:DC%2BC3cXps1aqu7c%3D, PID: 20568979
    • Pamukcu B, Lip GYH, Devitt A, Griffiths H, Shantsila E. The role of monocytes in atherosclerotic coronary artery disease. Ann Med. 2010;42:394–403.
    • (2010) Ann Med , vol.42 , pp. 394-403
    • Pamukcu, B.1    Lip, G.Y.H.2    Devitt, A.3    Griffiths, H.4    Shantsila, E.5
  • 32
    • 84877274395 scopus 로고    scopus 로고
    • Endothelial heterogeneity and adhesion molecules N-glycosylation: implications in leukocyte trafficking in inflammation
    • COI: 1:CAS:528:DC%2BC3sXntV2jurg%3D, PID: 23445551
    • Scott DW, Patel RP. Endothelial heterogeneity and adhesion molecules N-glycosylation: implications in leukocyte trafficking in inflammation. Glycobiology. 2013;23:622–33.
    • (2013) Glycobiology , vol.23 , pp. 622-633
    • Scott, D.W.1    Patel, R.P.2
  • 33
    • 84864286256 scopus 로고    scopus 로고
    • Role of endothelial N-glycan mannose residues in monocyte recruitment during atherogenesis
    • COI: 1:CAS:528:DC%2BC38XhtVCrsLnF, PID: 22723438
    • Scott DW, Chen J, Chacko BK, Traylor JG, Orr AW, Patel RP. Role of endothelial N-glycan mannose residues in monocyte recruitment during atherogenesis. Arterioscler Thromb Vasc Biol. 2012;32:e51–9.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. e51-e59
    • Scott, D.W.1    Chen, J.2    Chacko, B.K.3    Traylor, J.G.4    Orr, A.W.5    Patel, R.P.6
  • 34
    • 70349779564 scopus 로고    scopus 로고
    • P-selectin glycoprotein ligand-1 plays a crucial role in the selective recruitment of leukocytes into the atherosclerotic arterial wall
    • COI: 1:CAS:528:DC%2BD1MXht1Crtb%2FL, PID: 19818951
    • Huo Y, Xia L. P-selectin glycoprotein ligand-1 plays a crucial role in the selective recruitment of leukocytes into the atherosclerotic arterial wall. Trends Cardiovasc Med. 2009;19:140–5.
    • (2009) Trends Cardiovasc Med , vol.19 , pp. 140-145
    • Huo, Y.1    Xia, L.2
  • 35
    • 84860260276 scopus 로고    scopus 로고
    • The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?
    • COI: 1:CAS:528:DC%2BC38XhtFGjurvE, PID: 22256855
    • Cooper D, Iqbal AJ, Gittens BR, Cervone C, Perretti M. The effect of galectins on leukocyte trafficking in inflammation: sweet or sour? Ann N Y Acad Sci. 2012;1253:181–92.
    • (2012) Ann N Y Acad Sci , vol.1253 , pp. 181-192
    • Cooper, D.1    Iqbal, A.J.2    Gittens, B.R.3    Cervone, C.4    Perretti, M.5
  • 36
    • 77954424603 scopus 로고    scopus 로고
    • The glycan profile of endothelial cells in the present of tumor-conditioned medium and potential roles of β-1,6-GlcNAc branching on HUVEC conformation
    • COI: 1:CAS:528:DC%2BC3cXntlGjt7w%3D, PID: 20204678
    • Peng Y, Li J, Geng M. The glycan profile of endothelial cells in the present of tumor-conditioned medium and potential roles of β-1,6-GlcNAc branching on HUVEC conformation. Mol Cell Biochem. 2010;340:143–52.
    • (2010) Mol Cell Biochem , vol.340 , pp. 143-152
    • Peng, Y.1    Li, J.2    Geng, M.3
  • 37
    • 80055076022 scopus 로고    scopus 로고
    • Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands
    • COI: 1:CAS:528:DC%2BC3MXhtlykurvL, PID: 21911496
    • Chacko BK, Scott DW, Chandler RT, Patel RP. Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands. J Biol Chem. 2011;286:38738–47.
    • (2011) J Biol Chem , vol.286 , pp. 38738-38747
    • Chacko, B.K.1    Scott, D.W.2    Chandler, R.T.3    Patel, R.P.4
  • 39
    • 28444485987 scopus 로고    scopus 로고
    • Activation of human endothelial cells by tumor necrosis factor-alpha results in profound changes in the expression of glycosylation-related genes
    • PID: 16080149
    • García-Vallejo JJ, Van Dijk W, Van Het Hof B, Van Die I, Engelse MA, Van Hinsbergh VWM, et al. Activation of human endothelial cells by tumor necrosis factor-alpha results in profound changes in the expression of glycosylation-related genes. J Cell Physiol. 2006;206:203–10.
    • (2006) J Cell Physiol , vol.206 , pp. 203-210
    • García-Vallejo, J.J.1    Van Dijk, W.2    Van Het Hof, B.3    Van Die, I.4    Engelse, M.A.5    Van Hinsbergh, V.W.M.6
  • 40
    • 85024106779 scopus 로고    scopus 로고
    • • Jaillet C, Morelle W, Slomianny MC, Paget V, Tarlet G, Buard V, et al. Radiation-induced changes in the glycome of endothelial cells with functional consequences. Sci Rep. 2017;7. Important
    • • Jaillet C, Morelle W, Slomianny MC, Paget V, Tarlet G, Buard V, et al. Radiation-induced changes in the glycome of endothelial cells with functional consequences. Sci Rep. 2017;7. Important: in this paper, authors showed that N -glyosylation changes are associated with functional properties of endothelial cells.
    • In this paper, authors showed that N -glyosylation changes are associated with functional properties of endothelial cells
  • 41
    • 33748750415 scopus 로고    scopus 로고
    • Selectins and glycosyltransferases in leukocyte rolling in vivo
    • COI: 1:CAS:528:DC%2BD28XhtFCgtLvO, PID: 16956372
    • Sperandio M. Selectins and glycosyltransferases in leukocyte rolling in vivo. FEBS J. 2006;273:4377–89.
    • (2006) FEBS J , vol.273 , pp. 4377-4389
    • Sperandio, M.1
  • 42
    • 0036696903 scopus 로고    scopus 로고
    • Glycosylation in the control of selectin counter-receptor structure and function
    • COI: 1:CAS:528:DC%2BD38XotFehtrY%3D
    • Lowe JB. Glycosylation in the control of selectin counter-receptor structure and function. ImmunolRev. 2002;186:19–36.
    • (2002) ImmunolRev , vol.186 , pp. 19-36
    • Lowe, J.B.1
  • 44
    • 84981260270 scopus 로고    scopus 로고
    • Changes in IgG and total plasma protein glycomes in acute systemic inflammation
    • Novokmet M, Lukić E, Vučković F, Ðurić Ž, Keser T, Rajšl K, et al. Changes in IgG and total plasma protein glycomes in acute systemic inflammation. Sci Rep. 2014;4:1–10.
    • (2014) Sci Rep , vol.4 , pp. 1-10
    • Novokmet, M.1    Lukić, E.2    Vučković, F.3    Ðurić, Ž.4    Keser, T.5    Rajšl, K.6
  • 45
    • 84981215205 scopus 로고    scopus 로고
    • Changes in total plasma and serum N-glycome composition and patient-controlled analgesia after major abdominal surgery
    • COI: 1:CAS:528:DC%2BC28XhtlCisb%2FO, PID: 27501865
    • Gudelj I, Baciarello M, Ugrina I, De Gregori M, Napolioni V, Ingelmo PM, et al. Changes in total plasma and serum N-glycome composition and patient-controlled analgesia after major abdominal surgery. Sci Rep. 2016;6:31234.
    • (2016) Sci Rep , vol.6 , pp. 31234
    • Gudelj, I.1    Baciarello, M.2    Ugrina, I.3    De Gregori, M.4    Napolioni, V.5    Ingelmo, P.M.6
  • 46
    • 0031822970 scopus 로고    scopus 로고
    • Site localization of sialyl Lewis(x) antigen on alpha1-acid glycoprotein by high performance liquid chromatography-electrospray mass spectrometry
    • COI: 1:CAS:528:DyaK1cXltlCms7c%3D, PID: 9639536
    • Dage JL, Ackermann BL, Halsall HB. Site localization of sialyl Lewis(x) antigen on alpha1-acid glycoprotein by high performance liquid chromatography-electrospray mass spectrometry. Glycobiology. 1998;8:755–60.
    • (1998) Glycobiology , vol.8 , pp. 755-760
    • Dage, J.L.1    Ackermann, B.L.2    Halsall, H.B.3
  • 47
    • 0028981439 scopus 로고
    • Brinkman-van der Linden EC. Alpha 1-acid glycoprotein (orosomucoid): pathophysiological changes in glycosylation in relation to its function
    • van Dijk W, Havenaar EC, Brinkman-van der Linden EC. Alpha 1-acid glycoprotein (orosomucoid): pathophysiological changes in glycosylation in relation to its function. Glycoconj J 1995;12:227–233.
    • (1995) Glycoconj J , vol.12 , pp. 227-233
    • van Dijk, W.1    Havenaar, E.C.2
  • 48
    • 0029669985 scopus 로고    scopus 로고
    • Glycosylation of alpha 1-acid glycoprotein in septic shock: changes in degree of branching and in expression of sialyl Lewis(x) groups
    • COI: 1:CAS:528:DyaK28Xht1Shu70%3D, PID: 8785484
    • Brinkman-van der Linden EC, van Ommen EC, van Dijk W. Glycosylation of alpha 1-acid glycoprotein in septic shock: changes in degree of branching and in expression of sialyl Lewis(x) groups. Glycoconj J. 1996;13:27–31.
    • (1996) Glycoconj J , vol.13 , pp. 27-31
    • Brinkman-van der Linden, E.C.1    van Ommen, E.C.2    van Dijk, W.3
  • 49
    • 0031871803 scopus 로고    scopus 로고
    • Severe rheumatoid arthritis prohibits the pregnancy-induced decrease in alpha3-fucosylation of alpha1-acid glycoprotein
    • COI: 1:CAS:528:DyaK1cXls1Omtrc%3D, PID: 9881778
    • Havenaar EC, Axford JS, Brinkman-van der Linden EC, Alavi A, Van Ommen EC, van het Hof B, et al. Severe rheumatoid arthritis prohibits the pregnancy-induced decrease in alpha3-fucosylation of alpha1-acid glycoprotein. Glycoconj J. 1998;15:723–9.
    • (1998) Glycoconj J , vol.15 , pp. 723-729
    • Havenaar, E.C.1    Axford, J.S.2    Brinkman-van der Linden, E.C.3    Alavi, A.4    Van Ommen, E.C.5    van het Hof, B.6
  • 50
    • 0023821653 scopus 로고
    • 400-MHz 1H-NMR spectroscopy of fucosylated tetrasialyl oligosaccharides isolated from normal and cirrhotic alpha 1-acid glycoprotein
    • JM W, Fournet B, Konan D, Biou D, Durand G. 400-MHz 1H-NMR spectroscopy of fucosylated tetrasialyl oligosaccharides isolated from normal and cirrhotic alpha 1-acid glycoprotein. FEBS Lett. 1988;238:390–4.
    • (1988) FEBS Lett , vol.238 , pp. 390-394
    • Jm, W.1    Fournet, B.2    Konan, D.3    Biou, D.4    Durand, G.5
  • 51
    • 0031809628 scopus 로고    scopus 로고
    • Inflammation-induced expression of sialyl LewisX is not restricted to alpha1-acid glycoprotein but also occurs to a lesser extent on alpha1-antichymotrypsin and haptoglobin
    • EC B der L, de Haan PF, Havenaar EC, Van DW. Inflammation-induced expression of sialyl LewisX is not restricted to alpha1-acid glycoprotein but also occurs to a lesser extent on alpha1-antichymotrypsin and haptoglobin. GlycoconjJ. 1998;15:177–82.
    • (1998) GlycoconjJ , vol.15 , pp. 177-182
    • Ec b der, L.1    de Haan, P.F.2    Havenaar, E.C.3    Van, D.W.4
  • 52
    • 84885204309 scopus 로고    scopus 로고
    • Association between galactosylation of immunoglobulin G and improvement of rheumatoid arthritis during pregnancy is independent of sialylation
    • COI: 1:CAS:528:DC%2BC3sXhsVSgsbzI, PID: 24016253
    • Bondt A, Selman MHJ, Deelder AM, Hazes JMW, Willemsen SP, Wuhrer M, et al. Association between galactosylation of immunoglobulin G and improvement of rheumatoid arthritis during pregnancy is independent of sialylation. J Proteome Res. 2013;12:4522–31.
    • (2013) J Proteome Res , vol.12 , pp. 4522-4531
    • Bondt, A.1    Selman, M.H.J.2    Deelder, A.M.3    Hazes, J.M.W.4    Willemsen, S.P.5    Wuhrer, M.6    Dolhain, R.J.E.M.7
  • 53
    • 0023858223 scopus 로고
    • Alterations in carbohydrate composition of serum IgG from patients with rheumatoid arthritis and from pregnant women
    • COI: 1:CAS:528:DyaL1cXhsVymtr0%3D, PID: 3355256
    • Pekelharing JM, Hepp E, Kamerling JP, Gerwig GJ, Leijnse B. Alterations in carbohydrate composition of serum IgG from patients with rheumatoid arthritis and from pregnant women. Ann Rheum Dis. 1988;47:91–5.
    • (1988) Ann Rheum Dis , vol.47 , pp. 91-95
    • Pekelharing, J.M.1    Hepp, E.2    Kamerling, J.P.3    Gerwig, G.J.4    Leijnse, B.5
  • 55
    • 0023182253 scopus 로고
    • Interactions of IgG and [beta]-VLDL with aortic valve endothelium from hypercholesterolemic rabbits
    • COI: 1:CAS:528:DyaL1cXhtFSgs7g%3D, PID: 3322301
    • Sarphie TG. Interactions of IgG and [beta]-VLDL with aortic valve endothelium from hypercholesterolemic rabbits. Atherosclerosis. 1987;68:199–212.
    • (1987) Atherosclerosis , vol.68 , pp. 199-212
    • Sarphie, T.G.1
  • 56
    • 85053274824 scopus 로고    scopus 로고
    • •• Menni C, Gudelj I, MacDonald-Dunlop E, Mangino M, Zierer J, Bešić E, et al. Glycosylation profile of immunoglobulin G is cross-sectionally associated with cardiovascular disease risk score and subclinical atherosclerosis in two independent cohorts. Circ Res. 2018;CIRCRESAHA.117.312174. Very important
    • •• Menni C, Gudelj I, MacDonald-Dunlop E, Mangino M, Zierer J, Bešić E, et al. Glycosylation profile of immunoglobulin G is cross-sectionally associated with cardiovascular disease risk score and subclinical atherosclerosis in two independent cohorts. Circ Res. 2018;CIRCRESAHA.117.312174. Very important: in this study, it is shown that alterations of IgG N -glycome are an independent risk factor for CVDs by itself and associated with traditional ones.
    • In this study, it is shown that alterations of IgG N -glycome are an independent risk factor for CVDs by itself and associated with traditional ones
  • 57
    • 84954497285 scopus 로고    scopus 로고
    • • Suzuki H, Chikada M, Yokoyama MK, Kurokawa MS, Ando T, Furukawa H, et al. Aberrant glycosylation of lumican in aortic valve stenosis revealed by proteomic analysis. Int Heart J. 2016;57:104–11. Important
    • • Suzuki H, Chikada M, Yokoyama MK, Kurokawa MS, Ando T, Furukawa H, et al. Aberrant glycosylation of lumican in aortic valve stenosis revealed by proteomic analysis. Int Heart J. 2016;57:104–11. Important: this study showed that lumican is variously glycosylated and that highly glycosylated lumican molecules are decreased in aortic valve stenosis.
    • This study showed that lumican is variously glycosylated and that highly glycosylated lumican molecules are decreased in aortic valve stenosis
  • 58
    • 27644439090 scopus 로고    scopus 로고
    • From the cover: dysregulation of TGF-1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice
    • Wang X, Inoue S, Gu J, Miyoshi E, Noda K, Li W, et al. From the cover: dysregulation of TGF-1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice. Proc Natl Acad Sci 2005;102:15791–15796.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 15791-15796
    • Wang, X.1    Inoue, S.2    Gu, J.3    Miyoshi, E.4    Noda, K.5    Li, W.6
  • 59
    • 33646384614 scopus 로고    scopus 로고
    • Core fucosylation regulates epidermal growth factor receptor-mediated intracellular signaling
    • COI: 1:CAS:528:DC%2BD28XovVejtQ%3D%3D, PID: 16316986
    • Wang X, Gu J, Ihara H, Miyoshi E, Honke K, Taniguchi N. Core fucosylation regulates epidermal growth factor receptor-mediated intracellular signaling. J Biol Chem. 2006;281:2572–7.
    • (2006) J Biol Chem , vol.281 , pp. 2572-2577
    • Wang, X.1    Gu, J.2    Ihara, H.3    Miyoshi, E.4    Honke, K.5    Taniguchi, N.6
  • 60
    • 84885907154 scopus 로고    scopus 로고
    • The epidermal growth factor receptor and its ligands in cardiovascular disease
    • PID: 24132149
    • Makki N, Thiel KW, Miller FJ. The epidermal growth factor receptor and its ligands in cardiovascular disease. Int J Mol Sci. 2013;14:20597–613.
    • (2013) Int J Mol Sci , vol.14 , pp. 20597-20613
    • Makki, N.1    Thiel, K.W.2    Miller, F.J.3
  • 61
    • 3242806007 scopus 로고    scopus 로고
    • TGF-β1 and angiotensin networking in cardiac remodeling
    • COI: 1:CAS:528:DC%2BD2cXmtVWitbs%3D, PID: 15276467
    • Rosenkranz S. TGF-β1 and angiotensin networking in cardiac remodeling. Cardiovasc Res. 2004;63:423–32.
    • (2004) Cardiovasc Res , vol.63 , pp. 423-432
    • Rosenkranz, S.1
  • 64
    • 0034886921 scopus 로고    scopus 로고
    • Differential contribution of sialic acid to the function of repolarizing K(+) currents in ventricular myocytes
    • COI: 1:CAS:528:DC%2BD3MXlvFymtbY%3D, PID: 11443045
    • Ufret-Vincenty CA, Baro DJ, Santana LF, Schwetz TA, Norring SA, Ednie AR, et al. Differential contribution of sialic acid to the function of repolarizing K(+) currents in ventricular myocytes. Am J Physiol Cell Physiol. 2001;281:C464–74.
    • (2001) Am J Physiol Cell Physiol , vol.281 , pp. C464-C474
    • Ufret-Vincenty, C.A.1    Baro, D.J.2    Santana, L.F.3    Schwetz, T.A.4    Norring, S.A.5    Ednie, A.R.6
  • 65
    • 0347400132 scopus 로고    scopus 로고
    • Do defects in ion channel glycosylation set the stage for lethal cardiac arrhythmias?
    • PID: 11983936
    • Fozzard HA, Kyle JW. Do defects in ion channel glycosylation set the stage for lethal cardiac arrhythmias? Sci STKE. 2002;2002:pe19.
    • (2002) Sci STKE , vol.2002 , pp. pe19
    • Fozzard, H.A.1    Kyle, J.W.2
  • 66
    • 0035914395 scopus 로고    scopus 로고
    • Determinants involved in Kv1 potassium channel folding in the endoplasmic reticulum, glycosylation in the golgi, and cell surface expression
    • Zhu J, Watanabe I, Gomez B, Thornhill WB. Determinants involved in Kv1 potassium channel folding in the endoplasmic reticulum, glycosylation in the golgi, and cell surface expression. J Biol Chem. 2001;276:39428–37.
    • (2001) J Biol Chem , vol.276 , pp. 39428-39437
    • Zhu, J.1    Watanabe, I.2    Gomez, B.3    Thornhill, W.B.4
  • 67
    • 0035823555 scopus 로고    scopus 로고
    • Glycosylation increases potassium channel stability and surface expression in mammalian cells
    • COI: 1:CAS:528:DC%2BD3MXmslyltbk%3D, PID: 11427541
    • Khanna R, Myers MP, Lainé M, Papazian DM. Glycosylation increases potassium channel stability and surface expression in mammalian cells. J Biol Chem. 2001;276:34028–34.
    • (2001) J Biol Chem , vol.276 , pp. 34028-34034
    • Khanna, R.1    Myers, M.P.2    Lainé, M.3    Papazian, D.M.4
  • 68
    • 0032895513 scopus 로고    scopus 로고
    • Differential asparagine-linked glycosylation of voltage-gated K+ channels in mammalian brain and in transfected cells
    • COI: 1:CAS:528:DyaK1MXisFWns74%3D, PID: 10191360
    • Shi G, Trimmer JS. Differential asparagine-linked glycosylation of voltage-gated K+ channels in mammalian brain and in transfected cells. J Membr Biol. 1999;168:265–73.
    • (1999) J Membr Biol , vol.168 , pp. 265-273
    • Shi, G.1    Trimmer, J.S.2
  • 69
    • 80053405544 scopus 로고    scopus 로고
    • N- and O-linked glycosylation coordinate cell-surface localization of a cardiac potassium channel
    • COI: 1:CAS:528:DC%2BC3MXhsVCksr7M, PID: 21965632
    • Akhavan A. N- and O-linked glycosylation coordinate cell-surface localization of a cardiac potassium channel. J Physiol. 2011;589:4647–8.
    • (2011) J Physiol , vol.589 , pp. 4647-4648
    • Akhavan, A.1
  • 70
    • 84921931491 scopus 로고    scopus 로고
    • Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly
    • COI: 1:CAS:528:DC%2BC2MXhvVekurY%3D, PID: 25525262
    • Ednie AR, Bennett ES. Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly. J Biol Chem. 2015;290:2769–83.
    • (2015) J Biol Chem , vol.290 , pp. 2769-2783
    • Ednie, A.R.1    Bennett, E.S.2
  • 71
    • 0035958924 scopus 로고    scopus 로고
    • Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure
    • COI: 1:CAS:528:DC%2BD3MXls1Srsb8%3D, PID: 11369778
    • Ufret-Vincenty CA, Baro DJ, Lederer WJ, Rockman HA, Quiñones LE, Santana LF. Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure. J Biol Chem. 2001;276:28197–203.
    • (2001) J Biol Chem , vol.276 , pp. 28197-28203
    • Ufret-Vincenty, C.A.1    Baro, D.J.2    Lederer, W.J.3    Rockman, H.A.4    Quiñones, L.E.5    Santana, L.F.6
  • 72
    • 0025245551 scopus 로고
    • Neuraminidase treatment modifies the function of electroplax sodium channels in planar lipid bilayers
    • COI: 1:CAS:528:DyaK3MXhsF2hsrY%3D, PID: 2171591
    • Recio-Pinto E, Thornhill WB, Duch DS, Levinson SR, Urban BW. Neuraminidase treatment modifies the function of electroplax sodium channels in planar lipid bilayers. Neuron. 1990;5:675–84.
    • (1990) Neuron , vol.5 , pp. 675-684
    • Recio-Pinto, E.1    Thornhill, W.B.2    Duch, D.S.3    Levinson, S.R.4    Urban, B.W.5
  • 73
    • 0033214359 scopus 로고    scopus 로고
    • Glycosylation influences voltage-dependent gating of cardiac and skeletal muscle sodium channels
    • COI: 1:CAS:528:DyaK1MXmsFCntrg%3D, PID: 10501828
    • Zhang Y, Hartmann HA, Satin J. Glycosylation influences voltage-dependent gating of cardiac and skeletal muscle sodium channels. J Membr Biol. 1999;171:195–207.
    • (1999) J Membr Biol , vol.171 , pp. 195-207
    • Zhang, Y.1    Hartmann, H.A.2    Satin, J.3
  • 74
    • 0030933457 scopus 로고    scopus 로고
    • Contribution of sialic acid to the voltage dependence of sodium channel gating. A possible electrostatic mechanism
    • COI: 1:CAS:528:DyaK2sXhvFCltLg%3D, PID: 9089440
    • Bennett E, Urcan MS, Tinkle SS, Koszowski AG, Levinson SR. Contribution of sialic acid to the voltage dependence of sodium channel gating. A possible electrostatic mechanism. J Gen Physiol. 1997;109:327–43.
    • (1997) J Gen Physiol , vol.109 , pp. 327-343
    • Bennett, E.1    Urcan, M.S.2    Tinkle, S.S.3    Koszowski, A.G.4    Levinson, S.R.5
  • 75
    • 0035894883 scopus 로고    scopus 로고
    • Glycosylation alters steady-state inactivation of sodium channel Nav1.9/NaN in dorsal root ganglion neurons and is developmentally regulated
    • COI: 1:CAS:528:DC%2BD38XivV2r, PID: 11739573
    • Tyrrell L, Renganathan M, Dib-Hajj SD, Waxman SG. Glycosylation alters steady-state inactivation of sodium channel Nav1.9/NaN in dorsal root ganglion neurons and is developmentally regulated. J Neurosci. 2001;21:9629–37.
    • (2001) J Neurosci , vol.21 , pp. 9629-9637
    • Tyrrell, L.1    Renganathan, M.2    Dib-Hajj, S.D.3    Waxman, S.G.4
  • 76
    • 0026661995 scopus 로고
    • Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain
    • COI: 1:CAS:528:DyaK38XktVCkt7c%3D, PID: 1315775
    • Zuber C, Lackie PM, Catterall WA, Roth J. Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain. J Biol Chem. 1992;267:9965–71.
    • (1992) J Biol Chem , vol.267 , pp. 9965-9971
    • Zuber, C.1    Lackie, P.M.2    Catterall, W.A.3    Roth, J.4
  • 77
    • 0036487068 scopus 로고    scopus 로고
    • Isoform-specific effects of sialic acid on voltage-dependent Na+ channel gating: functional sialic acids are localized to the S5-S6 loop of domain I
    • COI: 1:CAS:528:DC%2BD38XislGnsrs%3D, PID: 11826157
    • Bennett ES. Isoform-specific effects of sialic acid on voltage-dependent Na+ channel gating: functional sialic acids are localized to the S5-S6 loop of domain I. J Physiol. 2002;538:675–90.
    • (2002) J Physiol , vol.538 , pp. 675-690
    • Bennett, E.S.1
  • 78
    • 84911926366 scopus 로고    scopus 로고
    • Sialic acids attached to N- and O-glycans within the Nav1.4 D1S5-S6 linker contribute to channel gating
    • COI: 1:CAS:528:DC%2BC2cXhvVGksrfI
    • Ednie AR, Harper JM, Bennett ES. Sialic acids attached to N- and O-glycans within the Nav1.4 D1S5-S6 linker contribute to channel gating. Biochim Biophys Acta - Gen Subj. 2015;1850:307–17.
    • (2015) Biochim Biophys Acta - Gen Subj , vol.1850 , pp. 307-317
    • Ednie, A.R.1    Harper, J.M.2    Bennett, E.S.3
  • 79
    • 84981161418 scopus 로고    scopus 로고
    • • Deng W, Ednie AR, Qi J, Bennett ES. Aberrant sialylation causes dilated cardiomyopathy and stress-induced heart failure. Basic Res Cardiol. 2016;111. Important
    • • Deng W, Ednie AR, Qi J, Bennett ES. Aberrant sialylation causes dilated cardiomyopathy and stress-induced heart failure. Basic Res Cardiol. 2016;111. Important: in this study, the authors associated sialylation changes with cardiomyopathy and heart failure.
    • In this study, the authors associated sialylation changes with cardiomyopathy and heart failure
  • 80
    • 70349515573 scopus 로고    scopus 로고
    • Regulated and aberrant glycosylation modulate cardiac electrical signaling
    • a, Harper JM, Norring S a, Schaffer L
    • Montpetit ML, Stocker PJ, Schwetz T a, Harper JM, Norring S a, Schaffer L, et al. Regulated and aberrant glycosylation modulate cardiac electrical signaling. Proc Natl Acad Sci U S A 2009;106:16517–16522.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16517-16522
    • Montpetit, M.L.1    Stocker, P.J.2    Schwetz, T.3
  • 82
    • 79961128693 scopus 로고    scopus 로고
    • Glycosylation and processing of pro-B-type natriuretic peptide in cardiomyocytes
    • Peng J, Jiang J, Wang W, Qi X, Sun XL, Wu Q. Glycosylation and processing of pro-B-type natriuretic peptide in cardiomyocytes. Biochem Biophys Res Commun 2011;411:593–598.
    • (2011) Biochem Biophys Res Commun , vol.411 , pp. 593-598
    • Peng, J.1    Jiang, J.2    Wang, W.3    Qi, X.4    Sun, X.L.5    Wu, Q.6
  • 83
    • 0029773198 scopus 로고    scopus 로고
    • Glycosylation is critical for natriuretic peptide receptor-B function
    • COI: 1:CAS:528:DyaK2sXhsFOmuw%3D%3D, PID: 8979258
    • Fenrick R, McNicoll N, De Léan A. Glycosylation is critical for natriuretic peptide receptor-B function. Mol Cell Biochem. 1996;165:103–9.
    • (1996) Mol Cell Biochem , vol.165 , pp. 103-109
    • Fenrick, R.1    McNicoll, N.2    De Léan, A.3
  • 85
    • 79957456283 scopus 로고    scopus 로고
    • Diverse molecular forms of plasma B-type natriuretic peptide in heart failure
    • COI: 1:CAS:528:DC%2BC3MXlsFKht74%3D, PID: 21340670
    • Nishikimi T, Minamino N, Nakao K. Diverse molecular forms of plasma B-type natriuretic peptide in heart failure. Curr Heart Fail Rep. 2011;8:140–6.
    • (2011) Curr Heart Fail Rep , vol.8 , pp. 140-146
    • Nishikimi, T.1    Minamino, N.2    Nakao, K.3
  • 86
    • 0030844852 scopus 로고    scopus 로고
    • Glycosylation of asparagine 24 of the natriuretic peptide receptor-B is crucial for the formation of a competent ligand binding domain
    • Fenrick R, Bouchard N, McNicoll N, De Léan A. Glycosylation of asparagine 24 of the natriuretic peptide receptor-B is crucial for the formation of a competent ligand binding domain. Mol Cell Biochem 1997;173:25–32.
    • (1997) Mol Cell Biochem , vol.173 , pp. 25-32
    • Fenrick, R.1    Bouchard, N.2    McNicoll, N.3    De Léan, A.4
  • 87
    • 13144267729 scopus 로고    scopus 로고
    • Treatment with drugs to lower blood pressure and blood cholesterol based on an individual’s absolute cardiovascular risk
    • COI: 1:CAS:528:DC%2BD2MXoslWhsA%3D%3D, PID: 15680460
    • Jackson R, Lawes CMM, Bennett DA, Milne RJ, Rodgers A. Treatment with drugs to lower blood pressure and blood cholesterol based on an individual’s absolute cardiovascular risk. Lancet. 2005;365:434–41.
    • (2005) Lancet , vol.365 , pp. 434-441
    • Jackson, R.1    Lawes, C.M.M.2    Bennett, D.A.3    Milne, R.J.4    Rodgers, A.5
  • 88
    • 33846996345 scopus 로고    scopus 로고
    • Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score
    • COI: 1:CAS:528:DC%2BD2sXhslCqtLk%3D, PID: 17299196
    • Ridker PM, Buring JE, Rifai N, Cook NR. Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. JAMA. 2007;297:611–9.
    • (2007) JAMA , vol.297 , pp. 611-619
    • Ridker, P.M.1    Buring, J.E.2    Rifai, N.3    Cook, N.R.4
  • 89
    • 36348937783 scopus 로고    scopus 로고
    • Assessing risk of myocardial infarction and stroke: new data from the Prospective Cardiovascular Munster (PROCAM) study
    • COI: 1:STN:280:DC%2BD2snpvF2isw%3D%3D
    • Assmann G, Schulte H, Cullen P, Seedorf U. Assessing risk of myocardial infarction and stroke: new data from the Prospective Cardiovascular Munster (PROCAM) study. Eur J Clin Investig. 2007;37:925–32.
    • (2007) Eur J Clin Investig , vol.37 , pp. 925-932
    • Assmann, G.1    Schulte, H.2    Cullen, P.3    Seedorf, U.4
  • 91
    • 84903159932 scopus 로고    scopus 로고
    • ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American college of cardiology/American heart association task force on practice guidelines
    • Goff DC, Lloyd-Jones DM, Bennett G, Coady S, D’Agostino RB, Gibbons R, et al. ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American college of cardiology/American heart association task force on practice guidelines. Circulation. 2013:2014.
    • (2014) Circulation , pp. 2013
    • Goff, D.C.1    Lloyd-Jones, D.M.2    Bennett, G.3    Coady, S.4    D’Agostino, R.B.5    Gibbons, R.6
  • 92
    • 39549093148 scopus 로고    scopus 로고
    • General cardiovascular risk profile for use in primary care: the Framingham heart study
    • PID: 18212285
    • D’Agostino RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, et al. General cardiovascular risk profile for use in primary care: the Framingham heart study. Circulation. 2008;117:743–53.
    • (2008) Circulation , vol.117 , pp. 743-753
    • D’Agostino, R.B.1    Vasan, R.S.2    Pencina, M.J.3    Wolf, P.A.4    Cobain, M.5    Massaro, J.M.6
  • 93
    • 0033044588 scopus 로고    scopus 로고
    • Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity
    • PID: 10052355
    • Umaña P, Jean-Mairet J, Moudry R, Amstutz H, Bailey JE. Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity. Nat Biotechnol. 1999;17:176–80.
    • (1999) Nat Biotechnol , vol.17 , pp. 176-180
    • Umaña, P.1    Jean-Mairet, J.2    Moudry, R.3    Amstutz, H.4    Bailey, J.E.5
  • 94
    • 77951529848 scopus 로고    scopus 로고
    • Therapeutic antibodies for autoimmunity and inflammation
    • COI: 1:CAS:528:DC%2BC3cXltV2lu7k%3D, PID: 20414204
    • Chan AC, Carter PJ. Therapeutic antibodies for autoimmunity and inflammation. Nat Rev Immunol. 2010;10:301–16.
    • (2010) Nat Rev Immunol , vol.10 , pp. 301-316
    • Chan, A.C.1    Carter, P.J.2
  • 95
    • 78751608551 scopus 로고    scopus 로고
    • The role of differential IgG glycosylation in the interaction of antibodies with FcγRs in vivo
    • COI: 1:CAS:528:DC%2BC38XpsFOjtL4%3D, PID: 21150612
    • Anthony RM, Nimmerjahn F. The role of differential IgG glycosylation in the interaction of antibodies with FcγRs in vivo. Curr Opin Organ Transplant. 2011;16:7–14.
    • (2011) Curr Opin Organ Transplant , vol.16 , pp. 7-14
    • Anthony, R.M.1    Nimmerjahn, F.2
  • 96
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • COI: 1:CAS:528:DC%2BD2cXnvFSgtr8%3D, PID: 15385656
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu C. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351:1296–305.
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.5
  • 99
    • 0023912648 scopus 로고
    • Age-related galactosylation of the N-linked oligosaccharides of human serum IgG
    • COI: 1:CAS:528:DyaL1cXktVCqtLc%3D, PID: 3367097
    • Parekh R, Roitt I, Isenberg D, Dwek R, Rademacher T. Age-related galactosylation of the N-linked oligosaccharides of human serum IgG. J Exp Med. 1988;167:1731–6.
    • (1988) J Exp Med , vol.167 , pp. 1731-1736
    • Parekh, R.1    Roitt, I.2    Isenberg, D.3    Dwek, R.4    Rademacher, T.5
  • 101
    • 0030996004 scopus 로고    scopus 로고
    • Structural changes of immunoglobulin G oligosaccharides with age in healthy human serum
    • COI: 1:CAS:528:DyaK2sXjtFajurY%3D, PID: 9147063
    • Yamada E, Tsukamoto Y, Sasaki R, Yagyu K, Takahashi N. Structural changes of immunoglobulin G oligosaccharides with age in healthy human serum. Glycoconj J. 1997;14:401–5.
    • (1997) Glycoconj J , vol.14 , pp. 401-405
    • Yamada, E.1    Tsukamoto, Y.2    Sasaki, R.3    Yagyu, K.4    Takahashi, N.5
  • 104
    • 85030025954 scopus 로고    scopus 로고
    • Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health
    • PID: 28951559, Important: this study shows thatN-glycosylation changes of IgG are associated with inflammation and metabolic health
    • • Plomp R, Ruhaak LR, Uh HW, Reiding KR, Selman M, Houwing-Duistermaat JJ, et al. Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health. Sci Rep. 2017;7:12325. Important: this study shows that N -glycosylation changes of IgG are associated with inflammation and metabolic health.
    • (2017) Sci Rep , vol.7 , pp. 12325
    • Plomp, R.1    Ruhaak, L.R.2    Uh, H.W.3    Reiding, K.R.4    Selman, M.5    Houwing-Duistermaat, J.J.6    Slagboom, P.E.7    Beekman, M.8    Wuhrer, M.9
  • 110
    • 84925151329 scopus 로고    scopus 로고
    • Women-specific factors to consider in risk, diagnosis and treatment of cardiovascular disease
    • COI: 1:CAS:528:DC%2BC2MXksVOktL8%3D
    • Harvey RE, Coffman KE, Miller VM. Women-specific factors to consider in risk, diagnosis and treatment of cardiovascular disease. Ronée Womens Heal (l Engl). 2015;11:239–57.
    • (2015) Ronée Womens Heal (l Engl) , vol.11 , pp. 239-257
    • Harvey, R.E.1    Coffman, K.E.2    Miller, V.M.3
  • 111
    • 85012906181 scopus 로고    scopus 로고
    • Sex differences: a resultant of an evolutionary pressure?
    • Della Torre S, Maggi A. Sex differences: a resultant of an evolutionary pressure? Cell Metab 2017. p. 499–505, 25.
    • (2017) Cell Metab , vol.25 , pp. 499-505
    • Della Torre, S.1    Maggi, A.2
  • 112
    • 85014756004 scopus 로고    scopus 로고
    • Sex hormones and sex chromosomes cause sex differences in the development of cardiovascular diseases
    • COI: 1:CAS:528:DC%2BC2sXms12gtL4%3D, PID: 28279969
    • Arnold AP, Cassis LA, Eghbali M, Reue K, Sandberg K. Sex hormones and sex chromosomes cause sex differences in the development of cardiovascular diseases. Arterioscler Thromb Vasc Biol. 2017;37:746–56.
    • (2017) Arterioscler Thromb Vasc Biol , vol.37 , pp. 746-756
    • Arnold, A.P.1    Cassis, L.A.2    Eghbali, M.3    Reue, K.4    Sandberg, K.5
  • 113
    • 84994430050 scopus 로고    scopus 로고
    • Mechanistic pathways of sex differences in cardiovascular disease
    • PID: 27807199
    • Regitz-Zagrosek V, Kararigas G. Mechanistic pathways of sex differences in cardiovascular disease. Physiol Rev. 2017;97:1–37.
    • (2017) Physiol Rev , vol.97 , pp. 1-37
    • Regitz-Zagrosek, V.1    Kararigas, G.2
  • 114
    • 84945543789 scopus 로고    scopus 로고
    • Genetics of cardiovascular disease: importance of sex and ethnicity
    • Winham SJ, de Andrade M, Miller VM. Genetics of cardiovascular disease: importance of sex and ethnicity. Atherosclerosis. 2014;241:219–28.
    • (2014) Atherosclerosis , vol.241 , pp. 219-228
    • Winham, S.J.1    de Andrade, M.2    Miller, V.M.3
  • 115
    • 85037661144 scopus 로고    scopus 로고
    • Proteomics in cardiovascular diseases: unveiling sex and gender differences in the era of precision medicine
    • COI: 1:CAS:528:DC%2BC2sXhvFKhurbP
    • Baetta R, Pontremoli M, Martinez Fernandez A, Spickett CM, Banfi C. Proteomics in cardiovascular diseases: unveiling sex and gender differences in the era of precision medicine. J Proteome. 2018;173:62–76.
    • (2018) J Proteome , vol.173 , pp. 62-76
    • Baetta, R.1    Pontremoli, M.2    Martinez Fernandez, A.3    Spickett, C.M.4    Banfi, C.5
  • 116
    • 80051724652 scopus 로고    scopus 로고
    • Human serum N-glycan profiles are age and sex dependent
    • PID: 21807702
    • Ding N, Sun HN, Sun W, Qu Y, Liu X, Yao Y, et al. Human serum N-glycan profiles are age and sex dependent. Age Ageing. 2011;40:568–75.
    • (2011) Age Ageing , vol.40 , pp. 568-575
    • Ding, N.1    Sun, H.N.2    Sun, W.3    Qu, Y.4    Liu, X.5    Yao, Y.6
  • 118
    • 77952487132 scopus 로고    scopus 로고
    • Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study
    • Van de Geijn FE, Wuhrer M, Selman MHJ, Willemsen SP, de Man YA, Deelder AM, et al. Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study. Arthritis Res Ther. 2009;11
    • (2009) Arthritis Res Ther , pp. 11
    • Van de Geijn, F.E.1    Wuhrer, M.2    Selman, M.H.J.3    Willemsen, S.P.4    de Man, Y.A.5    Deelder, A.M.6
  • 120
    • 85094927559 scopus 로고    scopus 로고
    • Estrogens regulate glycosylation of IgG in women and men
    • Important: this study shows thatN-glycosylation is regulated by sex hormones
    • • Ercan A, Kohrt WM, Cui J, Deane KD, Pezer M, Yu EW, et al. Estrogens regulate glycosylation of IgG in women and men. JCI Insight. 2017;2:1–9. Important: this study shows that N -glycosylation is regulated by sex hormones.
    • (2017) JCI Insight , vol.2 , pp. 1-9
    • Ercan, A.1    Kohrt, W.M.2    Cui, J.3    Deane, K.D.4    Pezer, M.5    Yu, E.W.6
  • 122
    • 0014264541 scopus 로고
    • The plasma lecithins:cholesterol acyltransferase reaction
    • COI: 1:CAS:528:DyaF1cXns1ahsQ%3D%3D, PID: 4868699
    • Glomset JA. The plasma lecithins:cholesterol acyltransferase reaction. J Lipid Res. 1968;9:155–67.
    • (1968) J Lipid Res , vol.9 , pp. 155-167
    • Glomset, J.A.1
  • 123
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. Atherosclerosis. Nature 2000. p. 233–241.
    • (2000) Nature , pp. 233-241
    • Lusis, A.J.1
  • 125
    • 0029790419 scopus 로고    scopus 로고
    • Sialic acids and the metabolism of low density lipoprotein
    • PID: 8864946
    • Melajärvi N, Gylling H, Miettinen TA. Sialic acids and the metabolism of low density lipoprotein. J Lipid Res. 1996;37:1625–31.
    • (1996) J Lipid Res , vol.37 , pp. 1625-1631
    • Melajärvi, N.1    Gylling, H.2    Miettinen, T.A.3
  • 126
    • 0033805561 scopus 로고    scopus 로고
    • Sialic acid content of low-density lipoprotein in women with coronary artery disease
    • COI: 1:CAS:528:DC%2BD3cXmtVWksL4%3D, PID: 10945239
    • Lindbohm N, Gylling H, R a R, T a M. Sialic acid content of low-density lipoprotein in women with coronary artery disease. J Lab Clin Med. 2000;136:110–5.
    • (2000) J Lab Clin Med , vol.136 , pp. 110-115
    • Lindbohm, N.1    Gylling, H.2    R a, R.3    T a, M.4
  • 127
    • 85015165134 scopus 로고    scopus 로고
    • • Krishnan S, Shimoda M, Sacchi R, Kailemia MJ, Luxardi G, Kaysen GA, et al. HDL glycoprotein composition and site-specific glycosylation differentiates between clinical groups and affects IL-6 secretion in lipopolysaccharide-stimulated monocytes. Sci Rep. 2017;7. Important
    • • Krishnan S, Shimoda M, Sacchi R, Kailemia MJ, Luxardi G, Kaysen GA, et al. HDL glycoprotein composition and site-specific glycosylation differentiates between clinical groups and affects IL-6 secretion in lipopolysaccharide-stimulated monocytes. Sci Rep. 2017;7. Important: this study shows that HDL glycosylation is an important feature for lipoprotein functions.
    • This study shows that HDL glycosylation is an important feature for lipoprotein functions
  • 128
    • 84905851466 scopus 로고    scopus 로고
    • Reduced apolipoprotein glycosylation in patients with the metabolic syndrome
    • PID: 25118169
    • Savinova OV, Fillaus K, Jing L, Harris WS, Shearer GC. Reduced apolipoprotein glycosylation in patients with the metabolic syndrome. PLoS One. 2014;9:e104833.
    • (2014) PLoS One , vol.9
    • Savinova, O.V.1    Fillaus, K.2    Jing, L.3    Harris, W.S.4    Shearer, G.C.5
  • 129
    • 84949009931 scopus 로고    scopus 로고
    • Combined high-density lipoprotein proteomic and glycomic profiles in patients at risk for coronary artery disease
    • COI: 1:CAS:528:DC%2BC2MXhslKhu7zK, PID: 26535788, Important: in this study, the authors showed that HDL glycosylation can be used as a biomarker; HDL glycome distinguished between individuals who had coronary artery disease from those who did not within a group of individuals equally at risk for heart disease
    • • Krishnan S, Huang J, Lee H, Guerrero A, Berglund L, Anuurad E, et al. Combined high-density lipoprotein proteomic and glycomic profiles in patients at risk for coronary artery disease. J Proteome Res. 2015;14:5109–18. Important: in this study, the authors showed that HDL glycosylation can be used as a biomarker; HDL glycome distinguished between individuals who had coronary artery disease from those who did not within a group of individuals equally at risk for heart disease.
    • (2015) J Proteome Res , vol.14 , pp. 5109-5118
    • Krishnan, S.1    Huang, J.2    Lee, H.3    Guerrero, A.4    Berglund, L.5    Anuurad, E.6
  • 130
    • 0032820681 scopus 로고    scopus 로고
    • Desialylation of human apolipoprotein E decreases its binding to human high-density lipoprotein and its ability to deliver esterified cholesterol to the liver
    • COI: 1:CAS:528:DyaK1MXmtVWns78%3D, PID: 10484062
    • Marmillot P, Rao MN, Liu QH, Lakshman MR. Desialylation of human apolipoprotein E decreases its binding to human high-density lipoprotein and its ability to deliver esterified cholesterol to the liver. Metabolism. 1999;48:1184–92.
    • (1999) Metabolism , vol.48 , pp. 1184-1192
    • Marmillot, P.1    Rao, M.N.2    Liu, Q.H.3    Lakshman, M.R.4
  • 131
    • 38849169686 scopus 로고    scopus 로고
    • Lipoprotein electrostatic properties regulate hepatic lipase association and activity
    • COI: 1:CAS:528:DC%2BD1cXovVelsg%3D%3D, PID: 18059528
    • Boucher JG, Nguyen T, Sparks DL. Lipoprotein electrostatic properties regulate hepatic lipase association and activity. Biochem Cell Biol. 2007;85:696–708.
    • (2007) Biochem Cell Biol , vol.85 , pp. 696-708
    • Boucher, J.G.1    Nguyen, T.2    Sparks, D.L.3
  • 132
    • 0032126274 scopus 로고    scopus 로고
    • t., Passarelli M, Quintão EC r. Lipoprotein desialylation simultaneously enhances the cell cholesterol uptake and impairs the reverse cholesterol transport system: in vitro evidences utilizing neuraminidase-treated lipoproteins and mouse peritoneal macrophages
    • Harada LM, Carvalho MD t., Passarelli M, Quintão EC r. Lipoprotein desialylation simultaneously enhances the cell cholesterol uptake and impairs the reverse cholesterol transport system: in vitro evidences utilizing neuraminidase-treated lipoproteins and mouse peritoneal macrophages. Atherosclerosis 1998;139:65–75.
    • (1998) Atherosclerosis , vol.139 , pp. 65-75
    • Harada, L.M.1    Carvalho, M.D.2
  • 133
    • 0023853763 scopus 로고
    • Blood serum atherogenicity associated with coronary atherosclerosis. Evidence for nonlipid factor providing atherogenicity of low-density lipoproteins and an approach to its elimination
    • COI: 1:STN:280:DyaL1c7js1Siug%3D%3D, PID: 3342473
    • Orekhov AN, Tertov VV, Pokrovsky SN, Adamova IY, Martsenyuk ON, Lyakishev AA, et al. Blood serum atherogenicity associated with coronary atherosclerosis. Evidence for nonlipid factor providing atherogenicity of low-density lipoproteins and an approach to its elimination. Circ Res. 1988;62:421–9.
    • (1988) Circ Res , vol.62 , pp. 421-429
    • Orekhov, A.N.1    Tertov, V.V.2    Pokrovsky, S.N.3    Adamova, I.Y.4    Martsenyuk, O.N.5    Lyakishev, A.A.6    Smirnov, V.N.7
  • 134
    • 0024383136 scopus 로고
    • Low-density lipoproteins isolated from the blood of patients with coronary heart disease induce the accumulation of lipids in human aortic cells
    • COI: 1:CAS:528:DyaL1MXkslGlurg%3D, PID: 2721653
    • Tertov VV, Orekhov AN, Martsenyuk ON, Perova NV, Smirnov VN. Low-density lipoproteins isolated from the blood of patients with coronary heart disease induce the accumulation of lipids in human aortic cells. Exp Mol Pathol. 1989;50:337–47.
    • (1989) Exp Mol Pathol , vol.50 , pp. 337-347
    • Tertov, V.V.1    Orekhov, A.N.2    Martsenyuk, O.N.3    Perova, N.V.4    Smirnov, V.N.5
  • 136
    • 84904618563 scopus 로고    scopus 로고
    • Modified low density lipoprotein and lipoprotein-containing circulating immune complexes as diagnostic and prognostic biomarkers of atherosclerosis and type 1 diabetes macrovascular disease
    • PID: 25050779
    • Orekhov AN, Bobryshev YV, Sobenin IA, Melnichenko AA, Chistiakov DA. Modified low density lipoprotein and lipoprotein-containing circulating immune complexes as diagnostic and prognostic biomarkers of atherosclerosis and type 1 diabetes macrovascular disease. Int J Mol Sci. 2014;15:12807–41.
    • (2014) Int J Mol Sci , vol.15 , pp. 12807-12841
    • Orekhov, A.N.1    Bobryshev, Y.V.2    Sobenin, I.A.3    Melnichenko, A.A.4    Chistiakov, D.A.5
  • 137
    • 0024401962 scopus 로고
    • Modification of low density lipoprotein by desialylation causes lipid accumulation in cultured cells: discovery of desialylated lipoprotein with altered cellular metabolism in the blood of atherosclerotic patients
    • COI: 1:CAS:528:DyaL1MXkslGksLc%3D, PID: 2751649
    • Orekhov AN, Tertov VV, Mukhin DN, Mikhailenko IA. Modification of low density lipoprotein by desialylation causes lipid accumulation in cultured cells: discovery of desialylated lipoprotein with altered cellular metabolism in the blood of atherosclerotic patients. Biochem Biophys Res Commun. 1989;162:206–11.
    • (1989) Biochem Biophys Res Commun , vol.162 , pp. 206-211
    • Orekhov, A.N.1    Tertov, V.V.2    Mukhin, D.N.3    Mikhailenko, I.A.4
  • 139
    • 0025327391 scopus 로고
    • Isolation of atherogenic modified (desialylated) low density lipoprotein from blood of atherosclerotic patients: separation from native lipoprotein by affinity chromatography
    • COI: 1:CAS:528:DyaK3cXhvFKisrs%3D, PID: 2322261
    • Tertov VV, Sobenin IA, Tonevitsky AG, Orekhov AN, Smirnov VN. Isolation of atherogenic modified (desialylated) low density lipoprotein from blood of atherosclerotic patients: separation from native lipoprotein by affinity chromatography. Biochem Biophys Res Commun. 1990;167:1122–7.
    • (1990) Biochem Biophys Res Commun , vol.167 , pp. 1122-1127
    • Tertov, V.V.1    Sobenin, I.A.2    Tonevitsky, A.G.3    Orekhov, A.N.4    Smirnov, V.N.5
  • 140
    • 0026704625 scopus 로고
    • Sialic acid content of human low density lipoproteins affects their interaction with cell receptors and intracellular lipid accumulation
    • COI: 1:CAS:528:DyaK38Xks1OktL8%3D, PID: 1512508
    • Orekhov AN, Tertov VV, Sobenin IA, Smirnov VN, Via DP, Guevara JJ, et al. Sialic acid content of human low density lipoproteins affects their interaction with cell receptors and intracellular lipid accumulation. J Lipid Res. 1992;33:805–17.
    • (1992) J Lipid Res , vol.33 , pp. 805-817
    • Orekhov, A.N.1    Tertov, V.V.2    Sobenin, I.A.3    Smirnov, V.N.4    Via, D.P.5    Guevara, J.J.6
  • 141
    • 0026011566 scopus 로고
    • Desialylated low density lipoprotein—naturally occurring modified lipoprotein with atherogenic potency
    • COI: 1:STN:280:DyaK3Mzjslajtw%3D%3D, PID: 1872910
    • Orekhov AN, Tertov VV, Mukhin DN. Desialylated low density lipoprotein—naturally occurring modified lipoprotein with atherogenic potency. Atherosclerosis. 1991;86:153–61.
    • (1991) Atherosclerosis , vol.86 , pp. 153-161
    • Orekhov, A.N.1    Tertov, V.V.2    Mukhin, D.N.3
  • 142
    • 0030045886 scopus 로고    scopus 로고
    • Desialylated LDL uptake in human and mouse macrophages can be mediated by a lectin receptor
    • COI: 1:CAS:528:DyaK28XhtlWhtr4%3D, PID: 8678920
    • Grewal T, Bartlett A, Burgess JW, Packer NH, Stanley KK. Desialylated LDL uptake in human and mouse macrophages can be mediated by a lectin receptor. Atherosclerosis. 1996;121:151–63.
    • (1996) Atherosclerosis , vol.121 , pp. 151-163
    • Grewal, T.1    Bartlett, A.2    Burgess, J.W.3    Packer, N.H.4    Stanley, K.K.5
  • 143
    • 0024431379 scopus 로고
    • Lipoprotein aggregation as an essential condition of intracellular lipid accumulation caused by modified low density lipoproteins
    • COI: 1:CAS:528:DyaL1MXlsFWisrY%3D, PID: 2775281
    • Tertov VV, Sobenin IA, Gabbasov ZA, Popov EG, Orekhov AN. Lipoprotein aggregation as an essential condition of intracellular lipid accumulation caused by modified low density lipoproteins. Biochem Biophys Res Commun. 1989;163:489–94.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 489-494
    • Tertov, V.V.1    Sobenin, I.A.2    Gabbasov, Z.A.3    Popov, E.G.4    Orekhov, A.N.5
  • 144
    • 0033789649 scopus 로고    scopus 로고
    • Role of the macrophage galactose lectin in the uptake of desialylated LDL
    • COI: 1:CAS:528:DC%2BD3cXns12ms7o%3D, PID: 11058718
    • Bartlett AL, Grewal T, De Angelis E, Myers S, Stanley KK. Role of the macrophage galactose lectin in the uptake of desialylated LDL. Atherosclerosis. 2000;153:219–30.
    • (2000) Atherosclerosis , vol.153 , pp. 219-230
    • Bartlett, A.L.1    Grewal, T.2    De Angelis, E.3    Myers, S.4    Stanley, K.K.5
  • 145
    • 0033866738 scopus 로고    scopus 로고
    • Statin treatment increases the sialic acid content of LDL in hypercholesterolemic patients
    • COI: 1:CAS:528:DC%2BD3cXltlWgsb8%3D, PID: 10924733
    • Lindbohm N, Gylling H, Miettinen TE, T a M. Statin treatment increases the sialic acid content of LDL in hypercholesterolemic patients. Atherosclerosis. 2000;151:545–50.
    • (2000) Atherosclerosis , vol.151 , pp. 545-550
    • Lindbohm, N.1    Gylling, H.2    Miettinen, T.E.3    T a, M.4
  • 146
    • 84924333440 scopus 로고    scopus 로고
    • Hypertriglyceridemia: a too long unfairly neglected major cardiovascular risk factor
    • PID: 25471221
    • Tenenbaum A, Klempfner R, Fisman EZ. Hypertriglyceridemia: a too long unfairly neglected major cardiovascular risk factor. Cardiovasc Diabetol. 2014;13:159.
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 159
    • Tenenbaum, A.1    Klempfner, R.2    Fisman, E.Z.3
  • 148
    • 78651094451 scopus 로고    scopus 로고
    • Inflammation in the pathophysiology of essential hypertension
    • PID: 20437401
    • Montecucco F, Pende A, Quercioli A, Mach F. Inflammation in the pathophysiology of essential hypertension. J Nephrol. 2011;24:23–34.
    • (2011) J Nephrol , vol.24 , pp. 23-34
    • Montecucco, F.1    Pende, A.2    Quercioli, A.3    Mach, F.4
  • 149
    • 84978230478 scopus 로고    scopus 로고
    • • Wang Y, Klarić L, Yu X, Thaqi K, Dong J, Novokmet M, et al. The association between glycosylation of immunoglobulin G and hypertension. Methe authors found that alterations of IgG N -glycome associate with hypertension.
    • • Wang Y, Klarić L, Yu X, Thaqi K, Dong J, Novokmet M, et al. The association between glycosylation of immunoglobulin G and hypertension. Med (United States). 2016;95. Important: in this study, the authors found that alterations of IgG N -glycome associate with hypertension.
    • (2016) Important: in this study
  • 150
    • 85024390715 scopus 로고    scopus 로고
    • Immunoglobulin G N-glycans as potential postgenomic biomarkers for hypertension in the Kazakh population
    • Gao Q, Dolikun M, Štambuk J, Wang H, Zhao F, Yiliham N, et al. Immunoglobulin G N-glycans as potential postgenomic biomarkers for hypertension in the Kazakh population. Omi A J Integr Biol. 2017;21
    • (2017) Omi A J Integr Biol , pp. 21
    • Gao, Q.1    Dolikun, M.2    Štambuk, J.3    Wang, H.4    Zhao, F.5    Yiliham, N.6
  • 153
    • 77954518174 scopus 로고    scopus 로고
    • Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans
    • COI: 1:CAS:528:DC%2BC3cXotleqt7Y%3D, PID: 20356825
    • Knezevic A, Gornik O, Polasek O, Pucic M, Redzic I, Novokmet M, et al. Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans. Glycobiology. 2010;20:959–69.
    • (2010) Glycobiology , vol.20 , pp. 959-969
    • Knezevic, A.1    Gornik, O.2    Polasek, O.3    Pucic, M.4    Redzic, I.5    Novokmet, M.6
  • 155
    • 84933074137 scopus 로고    scopus 로고
    • Novel protein glycan side-chain biomarker and risk of incident type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BC2MXos1Ojsbc%3D, PID: 25908766
    • Akinkuolie AO, Pradhan AD, Buring JE, Ridker PM, Mora S. Novel protein glycan side-chain biomarker and risk of incident type 2 diabetes mellitus. Arterioscler Thromb Vasc Biol. 2015;35:1544–50.
    • (2015) Arterioscler Thromb Vasc Biol , vol.35 , pp. 1544-1550
    • Akinkuolie, A.O.1    Pradhan, A.D.2    Buring, J.E.3    Ridker, P.M.4    Mora, S.5
  • 159
    • 0033582928 scopus 로고    scopus 로고
    • In vitro and in vivo alterations of enzymatic glycosylation in diabetes
    • COI: 1:CAS:528:DyaK1MXitFenu7Y%3D, PID: 10353622
    • Rellier N, Ruggiero-Lopez D, Lecomte M, Lagarde M, Wiernsperger N. In vitro and in vivo alterations of enzymatic glycosylation in diabetes. Life Sci. 1999;64:1571–83.
    • (1999) Life Sci , vol.64 , pp. 1571-1583
    • Rellier, N.1    Ruggiero-Lopez, D.2    Lecomte, M.3    Lagarde, M.4    Wiernsperger, N.5
  • 160
    • 0018179772 scopus 로고
    • Hydrolase activities in the rat aorta. I. Effects of diabetes mellitus and insulin treatment
    • COI: 1:CAS:528:DyaE1cXktVCisLg%3D, PID: 148980
    • Wolinsky H, Goldfischer S, Capron L, Capron F, Coltoff-Schiller B, Kasak L. Hydrolase activities in the rat aorta. I. Effects of diabetes mellitus and insulin treatment. Circ Res. 1978;42:821–31.
    • (1978) Circ Res , vol.42 , pp. 821-831
    • Wolinsky, H.1    Goldfischer, S.2    Capron, L.3    Capron, F.4    Coltoff-Schiller, B.5    Kasak, L.6
  • 161
    • 0026058094 scopus 로고
    • Serum sialic acid concentration and cardiovascular mortality
    • COI: 1:STN:280:DyaK3M7jsl2htw%3D%3D, PID: 1995133
    • Lindberg G, Eklund GA, Gullberg B, Råstam L. Serum sialic acid concentration and cardiovascular mortality. BMJ. 1991;302:143–6.
    • (1991) BMJ , vol.302 , pp. 143-146
    • Lindberg, G.1    Eklund, G.A.2    Gullberg, B.3    Råstam, L.4
  • 162
    • 0029027161 scopus 로고
    • Serum sialic acid concentration is elevated in IDDM especially in early diabetic nephropathy
    • COI: 1:STN:280:DyaK2M3ls1yjsA%3D%3D, PID: 7738493
    • Yokoyama H, Jensen JS, Jensen T, Deckert T. Serum sialic acid concentration is elevated in IDDM especially in early diabetic nephropathy. J Intern Med. 1995;237:519–23.
    • (1995) J Intern Med , vol.237 , pp. 519-523
    • Yokoyama, H.1    Jensen, J.S.2    Jensen, T.3    Deckert, T.4
  • 163
    • 84923074997 scopus 로고    scopus 로고
    • A novel protein glycan biomarker and future cardiovascular disease events
    • PID: 25249300
    • Akinkuolie AO, Buring JE, Ridker PM, Mora S. A novel protein glycan biomarker and future cardiovascular disease events. J Am Heart Assoc. 2014;3:e001221.
    • (2014) J Am Heart Assoc , vol.3
    • Akinkuolie, A.O.1    Buring, J.E.2    Ridker, P.M.3    Mora, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.