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Volumn 69, Issue 7, 2014, Pages 779-789

Glycans are a novel biomarker of chronological and biological ages

(27)  Krištić, Jasminka a   Vučković, Frano a   Menni, Cristina b   Klarić, Lucija a   Keser, Toma a   Beceheli, Ivona a   Pučić Baković, Maja a   Novokmet, Mislav a   Mangino, Massimo b   Thaqi, Kujtim a   Rudan, Pavao c   Novokmet, Natalija c   Šarac, Jelena c   Missoni, Saša c   Kolčić, Ivana d   Polašek, Ozren d   Rudan, Igor e   Campbell, Harry e   Hayward, Caroline f   Aulchenko, Yurii g   more..


Author keywords

Aging; Glycome; Glycosylation; Immunoglobulin G; Inflammation

Indexed keywords

AUTACOID; BIOLOGICAL MARKER; IMMUNOGLOBULIN G; POLYSACCHARIDE;

EID: 84902271562     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt190     Document Type: Article
Times cited : (293)

References (49)
  • 1
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span-from yeast to humans
    • doi:10.1126/ science.1172539
    • Fontana L, Partridge L, Longo VD. Extending healthy life span-from yeast to humans. Science. 2010;328:321-326. doi:10.1126/ science.1172539
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 4
    • 75749136871 scopus 로고    scopus 로고
    • Complex genetic regulation of protein glycosylation
    • doi:10.1039/ b910377e
    • Lauc G, Rudan I, Campbell H, Rudd PM. Complex genetic regulation of protein glycosylation. Mol Biosyst. 2010;6:329-335. doi:10.1039/ b910377e
    • (2010) Mol Biosyst , vol.6 , pp. 329-335
    • Lauc, G.1    Rudan, I.2    Campbell, H.3    Rudd, P.M.4
  • 5
    • 84862878445 scopus 로고    scopus 로고
    • Epigenetic modulation of the HeLa cell membrane N-glycome
    • doi:10.1016/j.bbagen.2011.12.007
    • Horvat T, Mužinić A, Barišić D, Bosnar MH, Zoldoš V. Epigenetic modulation of the HeLa cell membrane N-glycome. Biochim Biophys Acta. 2012;1820:1412-1419. doi:10.1016/j.bbagen.2011.12.007
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 1412-1419
    • Horvat, T.1    Mužinić, A.2    Barišić, D.3    Bosnar, M.H.4    Zoldoš, V.5
  • 6
    • 84857172895 scopus 로고    scopus 로고
    • Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome
    • doi:10.4161/ epi.7.2.18918
    • Zoldoš V, Horvat T, Novokmet M, et al. Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome. Epigenetics. 2012;7:164-172. doi:10.4161/ epi.7.2.18918
    • (2012) Epigenetics , vol.7 , pp. 164-172
    • Zoldoš, V.1    Horvat, T.2    Novokmet, M.3
  • 7
    • 81055154923 scopus 로고    scopus 로고
    • 5-AZA-2′-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer
    • doi:10.4161/epi.6.11.17977
    • Saldova R, Dempsey E, Pérez-Garay M, et al. 5-AZA-2′- deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer. Epigenetics. 2011;6:1362-1372. doi:10.4161/epi.6.11.17977
    • (2011) Epigenetics , vol.6 , pp. 1362-1372
    • Saldova, R.1    Dempsey, E.2    Pérez-Garay, M.3
  • 8
    • 84884992503 scopus 로고    scopus 로고
    • Epigenetic regulation of glycosylation is the quantum mechanics of biology
    • doi:10.1016/j.bbagen.2013.08.017
    • Lauc G, Vojta A, Zoldoš V. Epigenetic regulation of glycosylation is the quantum mechanics of biology. Biochim Biophys Acta. 2013;1840:65-70. doi:10.1016/j.bbagen.2013.08.017
    • (2013) Biochim Biophys Acta , vol.1840 , pp. 65-70
    • Lauc, G.1    Vojta, A.2    Zoldoš, V.3
  • 9
    • 0023912648 scopus 로고
    • Age-related galactosylation of the N-linked oligosaccharides of human serum IgG
    • doi:10.1084/jem.167.5.1731
    • Parekh R, Roitt I, Isenberg D, Dwek R, Rademacher T. Age-related galactosylation of the N-linked oligosaccharides of human serum IgG. J Exp Med. 1988;167:1731-1736. doi:10.1084/jem.167.5.1731
    • (1988) J Exp Med , vol.167 , pp. 1731-1736
    • Parekh, R.1    Roitt, I.2    Isenberg, D.3    Dwek, R.4    Rademacher, T.5
  • 10
    • 79953712954 scopus 로고    scopus 로고
    • Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health
    • doi:10.1021/pr1009959
    • Ruhaak LR, Uh HW, Beekman M, et al. Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health. J Proteome Res. 2011;10:1667-1674. doi:10.1021/pr1009959
    • (2011) J Proteome Res , vol.10 , pp. 1667-1674
    • Ruhaak, L.R.1    Uh, H.W.2    Beekman, M.3
  • 11
    • 77954518174 scopus 로고    scopus 로고
    • Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans
    • doi:10.1093/glycob/cwq051
    • Knezevic A, Gornik O, Polasek O, et al. Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans. Glycobiology. 2010;20:959-969. doi:10.1093/glycob/cwq051
    • (2010) Glycobiology , vol.20 , pp. 959-969
    • Knezevic, A.1    Gornik, O.2    Polasek, O.3
  • 12
    • 80054016444 scopus 로고    scopus 로고
    • High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations
    • doi:10.1074/mcp.M111.010090 M111.010090
    • Pucić M, Knezević A, Vidic J, et al. High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations. Mol Cell Proteomics. 2011;10:M111.010090. doi:10.1074/mcp.M111.010090
    • (2011) Mol Cell Proteomics , vol.10
    • Pucić, M.1    Knezević, A.2    Vidic, J.3
  • 13
    • 77956993579 scopus 로고    scopus 로고
    • Serum N-glycan profile shift during human ageing
    • doi:10.1016/j. exger.2010.08.009
    • Vanhooren V, Dewaele S, Libert C, et al. Serum N-glycan profile shift during human ageing. Exp Gerontol. 2010;45:738-743. doi:10.1016/j. exger.2010.08.009
    • (2010) Exp Gerontol , vol.45 , pp. 738-743
    • Vanhooren, V.1    Dewaele, S.2    Libert, C.3
  • 14
    • 84862843922 scopus 로고    scopus 로고
    • Alternative glycosylation modulates function of IgG and other proteins-implications on evolution and disease
    • doi:10.1016/j. bbagen.2011.12.004
    • Gornik O, Pavić T, Lauc G. Alternative glycosylation modulates function of IgG and other proteins-implications on evolution and disease. Biochim Biophys Acta. 2012;1820:1318-1326. doi:10.1016/j. bbagen.2011.12.004
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 1318-1326
    • Gornik, O.1    Pavić, T.2    Lauc, G.3
  • 15
    • 84868642198 scopus 로고    scopus 로고
    • Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1
    • doi:10.1038/nm.2862
    • Karsten CM, Pandey MK, Figge J, et al. Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1. Nat Med. 2012;18:1401-1406. doi:10.1038/nm.2862
    • (2012) Nat Med , vol.18 , pp. 1401-1406
    • Karsten, C.M.1    Pandey, M.K.2    Figge, J.3
  • 16
    • 34247215987 scopus 로고    scopus 로고
    • Enhanced binding affinity for FcγRIIIa of fucose-negative antibody is sufficient to induce maximal antibody-dependent cellular cytotoxicity
    • DOI 10.1016/j.molimm.2007.02.005, PII S0161589007000776
    • Masuda K, Kubota T, Kaneko E, et al. Enhanced binding affinity for FcgammaRIIIa of fucose-negative antibody is sufficient to induce maximal antibody-dependent cellular cytotoxicity. Mol Immunol. 2007;44:3122-3131. doi:10.1016/j.molimm.2007.02.005 (Pubitemid 46610515
    • (2007) Molecular Immunology , vol.44 , Issue.12 , pp. 3122-3131
    • Masuda, K.1    Kubota, T.2    Kaneko, E.3    Iida, S.4    Wakitani, M.5    Kobayashi-Natsume, Y.6    Kubota, A.7    Shitara, K.8    Nakamura, K.9
  • 17
    • 84873495247 scopus 로고    scopus 로고
    • Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers
    • doi:10.1371/journal.pgen.1003225
    • Lauc G, Huffman JE, Pučić M, et al. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. PLoS Genet. 2013;9:e1003225. doi:10.1371/journal.pgen.1003225
    • (2013) PLoS Genet , vol.9
    • Lauc, G.1    Huffman, J.E.2    Pučić, M.3
  • 18
    • 58149391280 scopus 로고    scopus 로고
    • Glycosylation of serum proteins in inflammatory diseases
    • doi:http://dx.doi. org/10.1155/2008/493289
    • Gornik O, Lauc G. Glycosylation of serum proteins in inflammatory diseases. Dis Markers. 2008;25:267-278. doi:http://dx.doi. org/10.1155/2008/ 493289
    • (2008) Dis Markers , vol.25 , pp. 267-278
    • Gornik, O.1    Lauc, G.2
  • 19
    • 84873495247 scopus 로고    scopus 로고
    • Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers
    • doi:10.1371/journal.pgen
    • Lauc G, Huffman J, Pučić M, et al. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. PLoS Genet. 2013;9:e1003225. doi:10.1371/journal.pgen
    • (2013) PLoS Genet , vol.9
    • Lauc, G.1    Huffman, J.2    Pučić, M.3
  • 20
    • 0016355478 scopus 로고
    • A new look at the statistical model identification
    • doi:10.1109/TAC.1974.1100705
    • Akaike H. A new look at the statistical model identification. IEEE Trans Automat Contr. 1974;19:716-723. doi:10.1109/TAC.1974.1100705
    • (1974) IEEE Trans Automat Contr , vol.19 , pp. 716-723
    • Akaike, H.1
  • 21
    • 78751608551 scopus 로고    scopus 로고
    • The role of differential IgG glycosylation in the interaction of antibodies with FcgammaRs in vivo
    • doi:10.1097/ MOT.0b013e328342538f
    • Anthony RM, Nimmerjahn F. The role of differential IgG glycosylation in the interaction of antibodies with FcgammaRs in vivo. Curr Opin Organ Transplant. 2011;16:7-14. doi:10.1097/ MOT.0b013e328342538f
    • (2011) Curr Opin Organ Transplant , vol.16 , pp. 7-14
    • Anthony, R.M.1    Nimmerjahn, F.2
  • 22
    • 84860235393 scopus 로고    scopus 로고
    • Novel roles for the IgG Fc glycan
    • doi:10.1007/ s10875-010-9405-9406
    • Anthony RM, Wermeling F, Ravetch JV. Novel roles for the IgG Fc glycan. Ann N Y Acad Sci. 2012;1253:170-180. doi:10.1007/ s10875-010-9405-6
    • (2012) Ann N y Acad Sci , vol.1253 , pp. 170-180
    • Anthony, R.M.1    Wermeling, F.2    Ravetch, J.V.3
  • 23
    • 84878553336 scopus 로고    scopus 로고
    • The regulatory power of glycans and their binding partners in immunity
    • doi:10.1016/j.it.2013.01.006
    • Johnson JL, Jones MB, Ryan SO, Cobb BA. The regulatory power of glycans and their binding partners in immunity. Trends Immunol. 2013;34:290-298. doi:10.1016/j.it.2013.01.006
    • (2013) Trends Immunol , vol.34 , pp. 290-298
    • Johnson, J.L.1    Jones, M.B.2    Ryan, S.O.3    Cobb, B.A.4
  • 24
    • 42649089750 scopus 로고    scopus 로고
    • Anti-inflammatory actions of intravenous immunoglobulin
    • DOI 10.1146/annurev.immunol.26.021607.090232
    • Nimmerjahn F, Ravetch JV. Anti-inflammatory actions of intravenous immunoglobulin. Annu Rev Immunol. 2008;26:513-533. doi:10.1146/ annurev.immunol.26.021607.090232 (Pubitemid 351600384
    • (2008) Annual Review of Immunology , vol.26 , pp. 513-533
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 25
    • 54449089342 scopus 로고    scopus 로고
    • In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner
    • doi:10.1073/pnas.0808248105
    • Albert H, Collin M, Dudziak D, Ravetch JV, Nimmerjahn F. In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner. Proc Natl Acad Sci U S A. 2008;105:15005-15009. doi:10.1073/pnas.0808248105
    • (2008) Proc Natl Acad Sci U S A. , vol.105 , pp. 15005-15009
    • Albert, H.1    Collin, M.2    Dudziak, D.3    Ravetch, J.V.4    Nimmerjahn, F.5
  • 26
    • 75749133580 scopus 로고    scopus 로고
    • The pro and anti-inflammatory activities of immunoglobulin G
    • doi:10.1136/ard.2009.117101
    • Lux A, Aschermann S, Biburger M, Nimmerjahn F. The pro and anti-inflammatory activities of immunoglobulin G. Ann Rheum Dis. 2010;69(suppl 1):i92-i96. doi:10.1136/ard.2009.117101
    • (2010) Ann Rheum Dis , vol.69 , Issue.SUPPL. 1
    • Lux, A.1    Aschermann, S.2    Biburger, M.3    Nimmerjahn, F.4
  • 27
    • 84878551340 scopus 로고    scopus 로고
    • N-glycomic biomarkers of biological aging and longevity: A link with inflammaging
    • doi:10.1016/j.arr.2012.02.002
    • Dall'olio F, Vanhooren V, Chen CC, Slagboom PE, Wuhrer M, Franceschi C. N-glycomic biomarkers of biological aging and longevity: A link with inflammaging. Ageing Res Rev. 2013;12:685-698. doi:10.1016/j.arr.2012.02.002
    • (2013) Ageing Res Rev , vol.12 , pp. 685-698
    • Dall'Olio, F.1    Vanhooren, V.2    Chen, C.C.3    Slagboom, P.E.4    Wuhrer, M.5    Franceschi, C.6
  • 28
    • 16344376370 scopus 로고    scopus 로고
    • Inflamm-Ageing and lifelong antigenic load as major determinants of ageing rate and longevity
    • doi:10.1016/j. febslet.2005 02055
    • De Martinis M, Franceschi C, Monti D, Ginaldi L. Inflamm-Ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett. 2005;579:2035-2039. doi:10.1016/j. febslet.2005.02.055
    • (2005) FEBS Lett , vol.579 , pp. 2035-2039
    • De Martinis, M.1    Franceschi, C.2    Monti, D.3    Ginaldi, L.4
  • 29
    • 0033911488 scopus 로고    scopus 로고
    • Inflamm-Aging An evolutionary perspective on immunosenescence
    • doi:10.1111/j.1749-6632.2000.tb06651.x
    • Franceschi C, Bonafè M, Valensin S, et al. Inflamm-Aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci. 2000;908:244-254. doi:10.1111/j.1749-6632.2000.tb06651.x
    • (2000) Ann N y Acad Sci , vol.908 , pp. 244-254
    • Franceschi, C.1    Bonafè, M.2    Valensin, S.3
  • 30
    • 37549057294 scopus 로고    scopus 로고
    • N-glycomic changes in serum proteins during human aging
    • doi:10.1089/rej.2007.0556
    • Vanhooren V, Desmyter L, Liu XE, et al. N-glycomic changes in serum proteins during human aging. Rejuvenation Res. 2007;10:521-531a. doi:10.1089/rej.2007.0556
    • (2007) Rejuvenation Res , vol.10
    • Vanhooren, V.1    Desmyter, L.2    Liu, X.E.3
  • 31
    • 61849180382 scopus 로고    scopus 로고
    • Variability, heritability and environmental determinants of human plasma N-glycome
    • doi:10.1021/pr800737u
    • Knezević A, Polasek O, Gornik O, et al. Variability, heritability and environmental determinants of human plasma N-glycome. J Proteome Res. 2009;8:694-701. doi:10.1021/pr800737u
    • (2009) J Proteome Res , vol.8 , pp. 694-701
    • Knezević, A.1    Polasek, O.2    Gornik, O.3
  • 32
  • 33
    • 84872685546 scopus 로고    scopus 로고
    • Genomics and epigenomics of the human glycome
    • doi:10.1007/ s10719-012-9397-y
    • Zoldoš V, Novokmet M, Bečeheli I, Lauc G. Genomics and epigenomics of the human glycome. Glycoconj J. 2013;30:41-50. doi:10.1007/ s10719-012-9397-y
    • (2013) Glycoconj J. , vol.30 , pp. 41-50
    • Zoldoš, V.1    Novokmet, M.2    Bečeheli, I.3    Lauc, G.4
  • 34
    • 0030996004 scopus 로고    scopus 로고
    • Structural changes of immunoglobulin G oligosaccharides with age in healthy human serum
    • DOI 10.1023/A:1018582930906
    • Yamada E, Tsukamoto Y, Sasaki R, Yagyu K, Takahashi N. Structural changes of immunoglobulin G oligosaccharides with age in healthy human serum. Glycoconj J. 1997;14:401-405. doi:10.1023/A: 1018582930906 (Pubitemid 27231681
    • (1997) Glycoconjugate Journal , vol.14 , Issue.3 , pp. 401-405
    • Yamada, E.1    Tsukamoto, Y.2    Sasaki, R.3    Yagyu, K.4    Takahashi, N.5
  • 35
    • 84861410115 scopus 로고    scopus 로고
    • Changes in plasma and IgG N-glycome during childhood and adolescence
    • doi:10.1093/glycob/cws062
    • Pucic M, Muzinic A, Novokmet M, et al. Changes in plasma and IgG N-glycome during childhood and adolescence. Glycobiology. 2012;22:975-982. doi:10.1093/glycob/cws062
    • (2012) Glycobiology , vol.22 , pp. 975-982
    • Pucic, M.1    Muzinic, A.2    Novokmet, M.3
  • 36
    • 84872576236 scopus 로고    scopus 로고
    • Metabolism of inflammation limited by AMPK and pseudo-starvation
    • doi:10.1038/nature11862
    • O'Neill LA, Hardie DG. Metabolism of inflammation limited by AMPK and pseudo-starvation. Nature. 2013;493:346-355. doi:10.1038/nature11862
    • (2013) Nature , vol.493 , pp. 346-355
    • O'Neill, L.A.1    Hardie, D.G.2
  • 37
    • 0032429137 scopus 로고    scopus 로고
    • The effect on IgG glycosylation of altering beta1, 4- galactosyltransferase-1 activity in B cells
    • doi:http://dx.doi.org/10.1093/ glycob/8.12.1215
    • Keusch J, Lydyard PM, Delves PJ. The effect on IgG glycosylation of altering beta1, 4-galactosyltransferase-1 activity in B cells. Glycobiology. 1998;8:1215-1220. doi:http://dx.doi.org/10.1093/ glycob/8.12.1215
    • (1998) Glycobiology , vol.8 , pp. 1215-1220
    • Keusch, J.1    Lydyard, P.M.2    Delves, P.J.3
  • 38
    • 84872806231 scopus 로고    scopus 로고
    • Genome-wide methylation profiles reveal quantitative views of human aging rates
    • doi:10.1016/j.molcel.2012.10.016
    • Hannum G, Guinney J, Zhao L, et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell. 2013;49:359-367. doi:10.1016/j.molcel.2012.10.016
    • (2013) Mol Cell , vol.49 , pp. 359-367
    • Hannum, G.1    Guinney, J.2    Zhao, L.3
  • 40
    • 84899056948 scopus 로고    scopus 로고
    • Heritability of and mortality prediction with a longevity phenotype: The Healthy Aging Index
    • doi:10.1093/gerona/ glt117
    • Sanders JL, Minster RL, Barmada MM, et al. Heritability of and mortality prediction with a longevity phenotype: The Healthy Aging Index. J Gerontol A Biol Sci Med Sci. in press. doi:10.1093/gerona/ glt117
    • J Gerontol A Biol Sci Med Sci. in Press
    • Sanders, J.L.1    Minster, R.L.2    Barmada, M.M.3
  • 42
    • 84873262839 scopus 로고    scopus 로고
    • A systematic review of leukocyte telomere length and age in adults
    • doi:http://dx.doi.org/10.1016/j.arr.2013.01.003
    • Müezzinler A, Zaineddin AK, Brenner H. A systematic review of leukocyte telomere length and age in adults. Ageing Res Rev. 2013;12:509-519. doi:http://dx.doi.org/10.1016/j.arr.2013.01.003
    • (2013) Ageing Res Rev , vol.12 , pp. 509-519
    • Müezzinler, A.1    Zaineddin, A.K.2    Brenner, H.3
  • 43
    • 0035937526 scopus 로고    scopus 로고
    • Glycosylation and the immune system
    • DOI 10.1126/science.291.5512.2370
    • Rudd PM, Elliott T, Cresswell P, Wilson IA, Dwek RA. Glycosylation and the immune system. Science. 2001;291:2370-2376. doi: 10.1126/ science.291.5512.2370 (Pubitemid 32231792
    • (2001) Science , vol.291 , Issue.5512 , pp. 2370-2376
    • Rudd, P.M.1    Elliott, T.2    Cresswell, P.3    Wilson, I.A.4    Dwek, R.A.5
  • 44
    • 67549135178 scopus 로고    scopus 로고
    • 10001 Dalmatians:" Croatia launches its national biobank
    • doi:10.3325/ cmj.2009 504
    • Rudan I, Marusić A, Janković S, et al. "10001 Dalmatians:" Croatia launches its national biobank. Croat Med J. 2009;50:4-6. doi:10.3325/ cmj.2009.50.4
    • (2009) Croat Med J. , vol.50 , pp. 4-6
    • Rudan, I.1    Marusić, A.2    Janković, S.3
  • 45
    • 84875631900 scopus 로고    scopus 로고
    • Cohort profile: TwinsUK and healthy ageing twin study
    • doi:10.1093/ije/dyr207
    • Moayyeri A, Hammond CJ, Valdes AM, Spector TD. Cohort profile: TwinsUK and healthy ageing twin study. Int J Epidemiol. 2013;42:76-85. doi:10.1093/ije/dyr207
    • (2013) Int J Epidemiol , vol.42 , pp. 76-85
    • Moayyeri, A.1    Hammond, C.J.2    Valdes, A.M.3    Spector, T.D.4
  • 46
    • 41449087577 scopus 로고    scopus 로고
    • HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software
    • doi:10.1016/j. ab.2007 12012
    • Royle L, Campbell MP, Radcliffe CM, et al. HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software. Anal Biochem. 2008;376:1-12. doi:10.1016/j. ab.2007.12.012
    • (2008) Anal Biochem , vol.376 , pp. 1-12
    • Royle, L.1    Campbell, M.P.2    Radcliffe, C.M.3
  • 47
    • 84975742481 scopus 로고    scopus 로고
    • Genomics meets glycomics: The first GWAS study of human N-glycome identifies HNF1alpha as a master regulator of plasma protein fucosylation
    • doi:10.1371/journal.pgen.1001256
    • Lauc G, Essafi A, Huffman JE, et al. Genomics meets glycomics: The first GWAS study of human N-glycome identifies HNF1alpha as a master regulator of plasma protein fucosylation. PLoS Genet. 2010;6:e1001256. doi:10.1371/journal. pgen.1001256
    • (2010) PLoS Genet , vol.6
    • Lauc, G.1    Essafi, A.2    Huffman, J.E.3
  • 48
    • 84863304598 scopus 로고    scopus 로고
    • R Core Team. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0. Accessed May 2013
    • R Core Team (2013). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0. http://www.R-project.org/. Accessed May 2013
    • (2013) R: A Language and Environment for Statistical Computing
  • 49
    • 51649087122 scopus 로고    scopus 로고
    • Biomarkers related to aging in human populations
    • doi:10.1016/S0065-2423(08)00405-8
    • Crimmins E, Vasunilashorn S, Kim JK, Alley D. Biomarkers related to aging in human populations. Adv Clin Chem. 2008;46:161-216. doi:10.1016/S0065- 2423(08)00405-8.
    • (2008) Adv Clin Chem , vol.46 , pp. 161-216
    • Crimmins, E.1    Vasunilashorn, S.2    Kim, J.K.3    Alley, D.4


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