Glycomic analysis of high density lipoprotein shows a highly sialylated particle

Journal of Proteome Research

Volumn 13, Issue 2, 2014, Pages 681-691

  Huang, Jincui ^a   Lee, Hyeyoung ^a   Zivkovic, Angela M ^a   Smilowitz, Jennifer T ^a   Rivera, Nancy ^a   German, J Bruce ^a   Lebrilla, Carlito B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

gangliosides; glycomics; glycoproteomics; HDL; mass spectrometry; sialylation

Indexed keywords

AMINO ACID SEQUENCE; CARBOHYDRATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GANGLIOSIDES; LIPOPROTEINS, HDL; MOLECULAR SEQUENCE DATA; N-ACETYLNEURAMINIC ACID; TANDEM MASS SPECTROMETRY;

EID: 84893867751     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr4012393     Document Type: Article

References (72)

1. Soran, H. HDL functionality Curr. Opin. Lipidol. 2012, 23 (4) 353-366
2. Asztalos, B. F.; Tani, M.; Schaefer, E. J. Metabolic and functional relevance of HDL subspecies Curr. Opin. Lipidol. 2011, 22 (3) 176-185
3. Ansell, B. J.; Fonarow, G. C.; Fogelman, A. M. The paradox of dysfunctional high-density lipoprotein Curr. Opin. Lipidol. 2007, 18 (4) 427-434
4. Sviridov, D. Elevated HDL cholesterol is functionally ineffective in cardiac transplant recipients: evidence for impaired reverse cholesterol transport Transplantation 2006, 81 (3) 361-366
5. McMahon, M. Dysfunctional proinflammatory high-density lipoproteins confer increased risk of atherosclerosis in women with systemic lupus erythematosus Arthritis Rheum. 2009, 60 (8) 2428-2437
6. Van Linthout, S. High-density lipoprotein at the interface of type 2 diabetes mellitus and cardiovascular disorders Curr. Pharm. Des. 2010, 16 (13) 1504-1516
7. Vaisar, T. HDL in humans with cardiovascular disease exhibits a proteomic signature Clin. Chim. Acta 2010, 411 (13-14) 972-979
8. Park, K. H. The functional and compositional properties of lipoproteins are altered in patients with metabolic syndrome with increased cholesteryl ester transfer protein activity Int. J. Mol. Med. 2010, 25 (1) 129-136
9. Jin, Y.; Manabe, T. Direct targeting of human plasma for matrix-assisted laser desorption/ionization and analysis of plasma proteins by time of flight-mass spectrometry Electrophoresis 2005, 26 (14) 2823-2834
10. Lee, J. Hyperexpression of N -acetylglucosaminyltransferase-III in liver tissues of transgenic mice causes fatty body and obesity through severe accumulation of Apo A-I and Apo B Arch. Biochem. Biophys. 2004, 426 (1) 18-31
11. Remaley, A. T. O-linked glycosylation modifies the association of apolipoprotein A-II to high density lipoproteins J. Biol. Chem. 1993, 268 (9) 6785-6790
12. Massey, J. B. Kinetics of transfer of alpha-tocopherol between model and native plasma lipoproteins Biochim. Biophys. Acta 1984, 793 (3) 387-392
13. Fazio, S. Preferential association of apolipoprotein E Leiden with very low density lipoproteins of human plasma J. Lipid Res. 1993, 34 (3) 447-453
14. Kawasaki, K. Sialic acid moiety of apolipoprotein E and its impact on the formation of lipoprotein particles in human cerebrospinal fluid Clin. Chim. Acta 2009, 402 (1-2) 61-66
15. Ueda, K. Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays Proteomics 2009, 9 (8) 2182-2192
16. Cabana, V. G. Influence of apoA-I and apoE on the formation of serum amyloid A-containing lipoproteins in vivo and in vitro J. Lipid Res. 2004, 45 (2) 317-325
17. Whitehead, A. S. Identification of novel members of the serum amyloid A protein superfamily as constitutive apolipoproteins of high density lipoprotein J. Biol. Chem. 1992, 267 (6) 3862-3867
18. O'Gorman, R. B. Correlation of immunologic and nutritional status with infectious complications after major abdominal trauma Surgery 1986, 99 (5) 549-556
19. Sanchez-Juanes, F. Glycosphingolipids from bovine milk and milk fat globule membranes: a comparative study. Adhesion to enterotoxigenic Escherichia coli strains Biol. Chem. 2009, 390 (1) 31-40
20. Senn, H. J. Gangliosides in normal human serum. Concentration, pattern and transport by lipoproteins Eur. J. Biochem. 1989, 181 (3) 657-662
21. Vaisar, T. Proteomics investigations of HDL: challenges and promise Curr. Vasc. Pharmacol. 2012, 10 (4) 410-421
22. Brousseau, T. Sequential ultracentrifugation micromethod for separation of serum lipoproteins and assays of lipids, apolipoproteins, and lipoprotein particles Clin. Chem. 1993, 39 (6) 960-964
23. Hua, S. Site-specific protein glycosylation analysis with glycan isomer differentiation Anal. Bioanal. Chem. 2012, 403 (5) 1291-1302
24. Nwosu, C. C. Simultaneous and Extensive Site-specific N- and O-Glycosylation Analysis in Protein Mixtures J. Proteome Res. 2011, 10 (5) 2612-2624
25. Seipert, R. R. Factors That Influence Fragmentation Behavior of N-Linked Glycopeptide Ions Anal. Chem. 2008, 80 (10) 3684-3698
26. Seipert, R. R.; Dodds, E. D.; Lebrilla, C. B. J. Proteome Res. 2009, 8 (2) 493
27. Hedrick, C. C. In vivo interactions of apoA-II, apoA-I, and hepatic lipase contributing to HDL structure and antiatherogenic functions J. Lipid Res. 2001, 42 (4) 563-570
28. Baumann, M. Association between carotid diameter and the advanced glycation endproduct Nepsilon-Carboxymethyllysine (CML) Cardiovasc. Diabetol. 2009, 8 (1) 45
29. Sakwe, A. M. Fetuin-A (α2HS-Glycoprotein) Is a major serum adhesive protein that mediates growth signaling in breast tumor cells J. Biol. Chem. 2010, 285 (53) 41827-41835
30. Jensen, L. E.; Whitehead, A. S. Regulation of serum amyloid A protein expression during the acute-phase response Biochem. J. 1998, 334 (3) 489-503
31. Rezaee, F. Proteomic analysis of high-density lipoprotein Proteomics 2006, 6 (2) 721-730
32. Gordon, S. High-density lipoprotein proteomics: identifying new drug targets and biomarkers by understanding functionality Curr. Cardiovasc. Risk Rep. 2010, 4 (1) 1-8
33. Hortin, G. L. Diverse range of small peptides associated with high-density lipoprotein Biochem. Biophys. Res. Commun. 2006, 340 (3) 909-15
34. Karlsson, H. Lipoproteomics II: mapping of proteins in high-density lipoprotein using two-dimensional gel electrophoresis and mass spectrometry Proteomics 2005, 5 (5) 1431-1445
35. Subramaniyam, D. C-36 peptide, a degradation product of alpha1-antitrypsin, modulates human monocyte activation through LPS signaling pathways Int. J. Biochem. Cell Biol. 2006, 38 (4) 563-575
36. Aldredge, D. Annotation of a serum N-glycan library for rapid identification of structures J. Proteome Res. 2012, 11 (3) 1958-1968
37. Hua, S. Comprehensive native glycan profiling with isomer separation and quantitation for the discovery of cancer biomarkers Analyst 2011, 136 (18) 3663-3671
38. Nwosu, C. C. Comparison of the human and bovine milk N-glycome via high-performance microfluidic chip liquid chromatography and tandem mass spectrometry J. Proteome Res. 2012, 11 (5) 2912-2924
39. Chu, C. S. Profile of native N-linked glycan structures from human serum using high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry Proteomics 2009, 9 (7) 1939-1951
40. Ix, J. H. Fetuin-A and kidney function in persons with coronary artery disease-data from the Heart and Soul Study Nephrol. Dial. Transplant. 2006, 21 (8) 2144-2151
41. Ruhaak, L. R. Hydrophilic interaction chromatography-based high-throughput sample preparation method for N-glycan analysis from total human plasma glycoproteins Anal. Chem. 2008, 80 (15) 6119-6126
42. Schauer, R. Sialic acids as regulators of molecular and cellular interactions Curr. Opin. Struct. Biol. 2009, 19 (5) 507-514
43. Varki, A. Sialic acids in human health and disease Trends in Molecular Medicine 2008, 14 (8) 351-360
44. Zhuo, Y.; Chammas, R.; Bellis, S. L. Sialylation of β1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis J. Biol. Chem. 2008, 283 (32) 22177-22185
45. Kumari, K. Receptor binding specificity of recent human H3N2 influenza viruses Virol. J. 2007, 4 (1) 42
46. Neu, U. Structural basis of GM1 ganglioside recognition by simian virus 40 Proc. Natl. Acad. Sci. 2008, 105 (13) 5219-5224
47. Boucher, J. G.; Nguyen, T.; Sparks, D. L. Lipoprotein electrostatic properties regulate hepatic lipase association and activity Biochem. Cell Biol. 2007, 85 (6) 696-708
48. Masson, D.; Athias, A.; Lagrost, L. Evidence for electronegativity of plasma high density lipoprotein-3 as one major determinant of human cholesteryl ester transfer protein activity J. Lipid Res. 1996, 37 (7) 1579-1590
49. Ghosh, P. Effects of chronic alcohol treatment on the synthesis, sialylation, and disposition of nascent apolipoprotein E by peritoneal macrophages of rats Am. J. Clin. Nutr. 2000, 72 (1) 190-198
50. Wopereis, S. Apolipoprotein C-III isofocusing in the diagnosis of genetic defects in O-glycan biosynthesis Clin. Chem. 2003, 49 (11) 1839-1845
51. Nwosu, C. C. J. Proteome Res. 2011, 10 (5) 2612
52. Ix, J. H. Fetuin-A and kidney function in persons with coronary artery disease-data from the heart and soul study Nephrol. Dial. Transplant. 2006, 21 (8) 2144-2151
53. Ix, J. H. The Associations of Fetuin-A With Subclinical Cardiovascular Disease in Community-Dwelling Persons: The Rancho Bernardo Study J. Am. Coll. Cardiol. 2011, 58 (23) 2372-2379
54. Ketteler, M. Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study Lancet 2003, 361 (9360) 827-833
55. Jahnen-Dechent, W. Fetuin-A Regulation of Calcified Matrix Metabolism Circ. Res. 2011, 108 (12) 1494-1509
56. Ketteler, M.; Schlieper, G.; Floege, J. Calcification and cardiovascular health: new insights into an old phenomenon Hypertension 2006, 47 (6) 1027-1034
57. Zauner, G. Protein glycosylation analysis by HILIC-LC-MS of Proteinase K-generated N- and O-glycopeptides J. Sep. Sci. 2010, 33 (6-7) 903-910
58. Corvol, P.; Jeunemaitre, X. Molecular genetics of human hypertension: role of angiotensinogen Endocr. Rev. 1997, 18 (5) 662-677
59. Gimenez-Roqueplo, A.-P. Role of N-glycosylation in human angiotensinogen J. Biol. Chem. 1998, 273 (33) 21232-21238
60. Ishioka, N.; Takahashi, N.; Putnam, F. W. Amino acid sequence of human plasma alpha 1B-glycoprotein: homology to the immunoglobulin supergene family Proc. Natl. Acad. Sci. 1986, 83 (8) 2363-2367
61. Nelsestuen, G. L.; Zhang, Y.; Martinez, M. B.; Key, N. S.; Jilma, B.; Verneris, M.; Sinaiko, A.; Kasthuri, R. S. Plasma protein profiling: unique and stable features of individuals Proteomics 2005, 5, 4012-4024
62. Harvey, S. B. O-Glycoside biomarker of apolipoprotein C3: responsiveness to obesity, bariatric surgery, and therapy with Metformin, to chronic or severe liver disease and to mortality in severe sepsis and graft vs host disease J. Proteome Res. 2008, 8 (2) 603-612
63. von Eckardstein, A. Apolipoprotein C-III(Lys58-Glu). Identification of an apolipoprotein C-III variant in a family with hyperalphalipoproteinemia J. Clin. Invest. 1991, 87 (5) 1724-1731
64. Riwanto, M; Rohrer, L.; Roschitzki, B.; Besler, C.; Mocharla, P.; Mueller, M.; Perisa, D.; Heinrich, K.; Altwegg, L.; von Eckardstein, A.; Lüscher, T. F.; Landmesser, U. Altered activation of endothelial anti- and proapoptotic pathways by high-density lipoprotein from patients with coronary artery disease: role of high-density lipoprotein-proteome remodeling Circulation 2013, 127, 891-904
65. Mangé, A.; Goux, A.; Badiou, S.; Patrier, L.; Maudelonde, T.; Cristol, J. P.; Solassol, J. HDL proteome in hemodialysis patients: a quantitative nanoflow liquid chromatography-tandem mass spectrometry approach PLoS One 2012, 7 e34107
66. Lee, H. Multiple precursor ion scanning of gangliosides and sulfatides with a reversed-phase microfluidic chip and quadrupole time-of-flight mass spectrometry Anal. Chem. 2012, 84 (14) 5905-5912
67. Senn, H.-J. Gangliosides in normal human serum Eur. J. Biochem. 1989, 181 (3) 657-662
68. Prokazova, N. V. The gangliosides of adult human aorta: intima, media and plaque Eur. J. Biochem. 1987, 167 (2) 349-52
69. Mukhin, D. N. Ganglioside content and composition of cells from normal and atherosclerotic human aorta Atherosclerosis 1989, 78 (1) 39-45
70. Bezuglov, V. V. [Gangliosides modulate lipoxygenase oxidation in human lymphocytes] Biokhimiia 1991, 56 (2) 267-272
71. Garner, A. E.; Smith, D. A.; Hooper, N. M. Sphingomyelin chain length influences the distribution of GPI-anchored proteins in rafts in supported lipid bilayers Mol. Membr. Biol. 2007, 24 (3) 233-242
72. Sorci-Thomas, M. G. Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers J. Lipid Res. 2012, 53 (9) 1890-1909