Sialic acids attached to N- and O-glycans within the Nav1.4 D1S5-S6 linker contribute to channel gating

Biochimica et Biophysica Acta - General Subjects

Volumn 1850, Issue 2, 2015, Pages 307-317

  Ednie, Andrew R ^a   Harper, Jean M ^a   Bennett, Eric S ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Ion channel gating; N glycosylation; Neuraminic acid; O glycosylation; Sialic acids; Voltage gated Na+ channels

Indexed keywords

GLYCAN DERIVATIVE; N GLYCAN DERIVATIVE; O GLYCAN DERIVATIVE; SIALIC ACID DERIVATIVE; SODIUM CHANNEL NAV1.4; UNCLASSIFIED DRUG; GLYCOPROTEIN; SCN4A PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CHO CELL LINE; CONTROLLED STUDY; DEPOLARIZATION; MUSCLE ACTION POTENTIAL; NERVE POTENTIAL; NONHUMAN; SIALYLATION; STATIC ELECTRICITY; STEADY STATE; ANIMAL; CRICETULUS; GENETICS; GLYCOSYLATION; HAMSTER; METABOLISM; PHYSIOLOGY;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; GLYCOPROTEINS; GLYCOSYLATION; ION CHANNEL GATING; NAV1.4 VOLTAGE-GATED SODIUM CHANNEL; SIALIC ACIDS;

EID: 84911926366     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.10.027     Document Type: Article

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