Discontinuation of fucose therapy in LADII causes rapid loss of selectin ligands and rise of leukocyte counts

Blood

Volumn 97, Issue 1, 2001, Pages 330-332

  Lühn, Kerstin ^b   Marquardt, Thorsten ^b   Harms, Erik ^a   Vestweber, Dietmar ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FUCOSE; GLYCOCONJUGATE; LIGAND; PADGEM PROTEIN; SELECTIN;

ARTICLE; BINDING AFFINITY; CASE REPORT; ENDOTHELIUM; HUMAN; HUMAN CELL; LEUKOCYTE; LEUKOCYTE ADHESION DEFICIENCY; LEUKOCYTE COUNT; LIGAND BINDING; MALE; NEUTROPHIL; PRESCHOOL CHILD; PRIORITY JOURNAL;

EID: 0035165830     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.1.330     Document Type: Article

References (19)

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2. The α-(1,3) fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis
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4. Rambam-Hasharon syndrome of psychomotor retardation, short stature, defective neutrophil motility, and Bombay phenotype
5. Leukocyte adhesion deficiency type II
6. In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes
7. In vivo neutrophil and lymphocyte function studies in a patient with leukocyte adhesion deficiency type II
8. Leukocyte adhesion deficiency type II is a generalized defect of de novo GDP-fucose biosynthesis: Endothelial cell fucosylation is not required for neutrophil rolling on human nonlymphoid endothelium
9. Correction of leukocyte adhession deficiency type II with oral fucose
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11. Five TNF-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes
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13. Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL-60 cells
14. A novel glycosulfopeptide binds to P-selectin and inhibits leukocyte adhesion to P-selectin
15. Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment
16. Defective intracellular activity of GDP-D-mannose-4,6-dehydratase in leukocyte adhesion deficiency type II syndrome
17. Fucose supplementation in leukocyte adhesion deficiency type II
18. Decreased availability of GDP-L-fucose in a patient with LAD II with normal GDP-D-mannose dehydratase and FX protein activities
19. A new type of carbohydrate-deficient glycoprotein syndrome due to a decreased import of GDP-fucose into the golgi