Desialylated LDL uptake in human and mouse macrophages can be mediated by a lectin receptor

Atherosclerosis

Volumn 121, Issue 1, 1996, Pages 151-163

  Grewal, Thomas ^a   Bartlett, Anna ^a   Burgess, James W ^a,c   Packer, Nicolle H ^b   Stanley, Keith K ^a  

^a HEART RESEARCH INSTITUTE   (Australia)

^b MACQUARIE UNIVERSITY   (Australia)

^c NONE   (Canada)

Author keywords

Desialylation; LDL; Lectin; Macrophage; Receptor

Indexed keywords

CHOLESTEROL; CHOLESTEROL ESTER; IODINE 125; LECTIN RECEPTOR; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR;

ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; FOAM CELL; HUMAN; HUMAN CELL; LIPID STORAGE; NORMAL HUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0030045886     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9150(95)05715-3     Document Type: Article

References (55)

1. Schaffner T, Taylor K, Bartucci K, Fischer-Dzoga K, Beeson J, Glagow S, Wissler L. Arterial foam cell with distinctive immuno-rnorphologic and histochemical features of macrophages. Am J Pathol 1980;100:57-73.
2. Faggioto A, Taylor K, Harker L. Studies of hyperocholesteremia in the nonhuman primate. I. Changes that lead to fatty streak formation. Arteriosclerosis 1984;4: 323-340.
3. Gerrity RG. The role of the monocyte in atherogenesis. I. Transition of blood borne monocytes into foam cells in fatty lesions. Am J Pathol 1981;103:181-190.
4. Haberland ME, Fogelman AM. The role of altered lipoproteins in the pathogenesis of atherosclerosis. Am Heart J 1987;113:573-577.
5. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol. Modifications of low-density lipoproteins that increase its atherogenicity. N Engl J Med 1989;320:915-924.
6. Geng YJ, Hansson GK. Interferon-γ inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages. J Clin Invest 1992;89: 1322-1330.
7. Mahley RW, Innerarity TL, Weisgraber KH, Oh SY. Altered metabolism (in vivo and in vitro) of plasma lipoproteins after selective chemical modification of lysine residues of the apoproteins. J Clin Invest 1979;64:743-750.
8. Weisgraber KH, Innerarity TL, Mahley RW. Role of lysine residues of plasma proteins in high affinity binding to cell surface receptors in human fibroblasts. J Biol Chem 1978;253:9053-9062.
9. Tertov VV, Sobenin IA, Gabbasov ZA, Popov EG, Orekhov AE. Lipoprotein aggregation as an essential condition of intracellular lipid accumulation caused by modified low density lipoproteins. Biochem Biophys Res Commun 1989;163:489-494.
10. Khoo JC, Miller E, McLaughlin P, Steinberg D. Enhanced macrophage uptake of low density lipoprotein after self-aggregation. Arteriosclerosis 1988;8:348-358.
11. Orekhov AN, Tertov VV, Mukhin DN, Mikhailenko IA. Modification of low density lipoprotein by desialylation causes lipid accumulation in cultured cells. Discovery of desialylated lipoprotein with altered cellular metabolism in the blood of atherosclerotic patients. Biochem Biophys Res Commun 1989;162:206-211.
12. Orekhov AN, Tertov VV, Mukhin DN. Desialylated low density lipoprotein - naturally occurring lipoprotein with atherogenic potency. Atherosclerosis 1991;86:153-161.
13. Orekhov AN, Tertov VV, Sobenin IA, Smirnov VN, Via DP, Guevara J Jr, Gotto AM Jr, Morrisett JD. Sialic acid content of human low density lipoproteins affects their interaction with cell receptors and intracellular accumulation. J Lipid Res 1992;33:805-817.
14. Tertov VV, Sobenin IA, Gabbasov ZA, Popov EG, Jaakkola O, Solakivi T, Nikkari T, Smirnov VN, Orekhov AN. Multiple-modified desialylated low density lipoproteins that cause intracellular lipid accumulation. Lab Invest 1992;67:665-675.
15. Tertov VV, Orekhov AN, Sobenin IA, Morrisett JD, Gotto AM Jr, Guevara JG Jr. Carbohydrate composition of protein and lipid components in sialic acid-rich and -poor low density lipoproteins from subjects with and without coronary artery disease. J Lipid Res 1993;34: 365-375.
16. Ruelland A, Gallou G, Legras B, Paillard F, Cloarec L. LDL sialic acid content in patients with coronary artery disease. Clin Chim Acta 1993;221:127-133.
17. Orekhov AN, Tertov VV, Pokrovsky SN, Adamova IYu, Martsenyuk ON, Lyakishev AA, Smirnov VN. Blood serum atherogenicity associated with coronary atherosclerosis. Evidence for nonlipid factor providing atherogenicity of low density lipoproteins and an approach to its elimination. Circ Res 1988;62:421-429.
18. Tertov VV, Orekhov AN, Martsenyuk ON, Perova NV, Smirnov VN. Low density lipoproteins isolated from the blood of patients with coronary heart disease induce the accumulation of lipids in human aortic cells. Exp Mol Pathol 1989;50:337-347.
19. Filipovic I, Buddecke E. Role of net charge of low density lipoproteins in high affinity binding and uptake by cultured cells. Biochem Biophys Res Commun 1979;88:485-490.
20. Windler E, Greeve J, Levkau B, Kolb-Bachhofen V, Daerr W, Greten H. The human asialoglycoprotein receptor is a possible binding site for low density lipoprotein and chylomicron remnants. Biochem J 1991;276:79-89.
21. Burgess JW, Stanley KK. 17α-Ethinylestradiol increases transcytosis of asialoglycoproteins in rat liver. J Biol Chem 1994;269:3482-3488.
22. Ashwell G, Harford J. Carbohydrate-specific receptors of the rat liver. Ann Rev Biochem 1982;51:531-554.
23. Spiess M. The asialoglycoprotein receptor: a model for endocytic transport receptors. Biochemistry 1990;29: 10009-10018.
24. Ishibashi S, Hammer RE, Herz J. Asialoglycoprotein receptor deficiency in mice lacking the minor receptor subunit. J Biol Chem 1994;269:27 803-27 806.
25. Chung BH, Segrest JP, Ray MJ, Brunzell JD, Hokason JE, Krauss RM, Beaudine K. Single vertical spin density gradient ultracentrifugation. Methods Enzymol 1986;128: 181-209.
26. Kritharides L, Jessup W, Gifford J, Dean RT. A method for defining the stages of low-density lipoprotein oxidation by the separation of cholesterol- and cholesteryl ester-oxidation products using HPLC. Anal Biochem 1993;213:79-89.
27. Sattler W, Mohr D, Stocker R. Rapid isolation of HDL LDL and VLDL and assessment of their peroxidation by HPLC post-column chemiluminescence detection. Methods Enzymol 1994;223:469-489.
28. Camejo G, Lopez A, Lopez F, Quinones J. Interaction of low density lipoproteins with arterial proteoglycans: the role of charge and sialic acid content. Atherosclerosis 1985;55:93-105.
29. Basu SK, Goldstein JL, Anderson GW, Brown MS. Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemnia fibroblasts. Proc Natl Acad Sci USA 1976;73:3178-3182.
30. Skoza L, Mohos S. Stable thiobarbituric acid chromophore with dimethyl sulfoxide. Biochem J 1976;159: 457-462.
31. Yang C-Y, Chen S-H, Giaturco SH, Bradley WA, Sparrow JT, Tanimura M, Li W-H, Sparrow DA, DeLoof H, Rosseneu M, Lee F-S, Gu Z-W, Gotto AM Jr, Chan L. Isolation and characterization of sulfhydryl and disulfide peptides of human apolipoprotein B-100. Nature 1986;323:738-743.
32. Jessup W, Mander EM, Dean RT. The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophages. Biochim Biophys Acta 1992;1126:167-177.
33. Sundström C, Nilsson K. Establishment and characterization of a human cystiocytotic lymphoma cell line (U-937). Int J Cancer 1976;17:565-577.
34. Gidlund M, Rossi P, Cotran P, Ramstedt U, Wigzell H. In human monocytes a strong correlation exists between expression of the M3 antigen, Fc-mediated phagocytotic activity and failure to participate in extracellular antibody-dependant cytotoxicity. Eur J Immunol 1988;18: 477-480.
35. Brown MS, Goldstein JL, Krieger M, Ho YK, Anderson RGW. Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins. J Cell Biol 1979;82:597-613.
36. Fraker PJ, Speck JC. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. Biochem Biophys Res Commun 1978;80:849-857.
37. Gough NM. Rapid and quantitative preparation of cytoplasmatic RNA from small numbers of cells. Anal Biochem 1988;173:93-95.
38. Haines DS, Gillespie D. RNA abundance measured by a lysate RNase protection assay. Biotechniques 1992;12: 736-741.
39. Yamamoto T, Davis CG, Brown MS, Schneider WJ, Casey ML, Goldstein JL, Russell DW. The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA. Cell 1984;39:27-38.
40. Matsumoto A, Naito M, Itakura H, Ikemoto S, Asaoka H, Hayakawa I, Kanamori H, Aburatani H, Takaku F, Suzuki H, Kobari Y, Miyai T, Takahashi K, Cohen EH, Wydro R, Houseman DE, Kodama T. Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions. Proc Natl Acad Sci USA 1990;87:9133-9137.
41. Taniguchi T, Ishikawa Y, Tsunemitsu M, Fukuzaki H. The structures of the asparagine-linked sugar chains of human apolipoprotein B-100. Arch Biochem Biophys 1989;273:197-205.
42. Brown MS, Goldstein JL. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu Rev Biochem 1983;52:223-261.
43. Suzuki K, Sakata N, Kitani A, Hara M, Hirose T, Hirose W, Norioka K, Harigai M, Kawagoe M, Nakamura H. Characterization of human monocytic cell line, U937, in taking up acetylated low-density lipoprotein and cholesteryl ester accumulation. A flow cytrometric and HPLC study. Biochim Biophys Acta 1990;1042:210-216.
44. Goldstein JL, Ho YK, Basu SK, Brown MS. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein producing massive cholesterol deposition. Proc Natl Acad Sci USA 1979; 76:333-337.
45. Fogelman AM, Haberland ME, Seager RDJ, Hokom M, Edwards PA. Factors regulating the activities of low density lipoprotein receptor and the scavenger receptor on human monocyte-macrophages. J Lipid Res 1981;22: 1131-1141.
46. Ohh M, Smith CA, Carpenito C, Takei F. Regulation of intercellular adhesion molecule-1 gene expression involves multiple mRNA stabilisation mechanisms: effect of interferon-gamma and phorbol myristyl acetate. Blood 1994;84:2632-2639.
47. Hara H, Tanishita H, Yokoyama S, Tajima S, Yamamoto A. Induction of acetylated LDL receptor and suppression of low density lipoprotein receptor on the cells of human monocytic leukemia cell line (THP-1). Biochem Biophys Res Commun 1987;146:802-808.
48. Moulton KS, Wu H, Barnett J, Parthasarathy S, Glass CK. Regulated expression of the human acetylated low density lipoprotein receptor gene and isolation of promoter sequences. Proc Natl Acad Sci USA 1992;89:8102-8106.
49. Snyder ML, Polacek D, Scanu AM, Fless GM. Comparative binding and degradation of lipoproteins (a) and low density lipoprotein by human monocyte-derived macrophages. J Biol Chem 1992;267:339-346.
50. Sagawa J, Miyagi T, Tsuiki S. Effects of OK-432 activiation on the sialidase activities of rat peritoneal macrophages. J Biochem Tokyo 1990;107:452-456.
51. Ii M, Kurata H, Itoh N, Yamashina I, Kawasaki T. Molecular cloning and 1 sequence analysis of cDNA encoding the macrophage lectin specific for galactose and N-acetylgalactoseamine. J Biol Chem 1990;265:11 295-11 298.
52. Ozaki K, Ii M, Itoh N, Kawasaki T. Expression of a functional asialoglycoprotein receptor through transfection of a cloned cDNA that encodes a macrophage lectin. J Biol Chem 1992;267:9229-9235.
53. Lee YC, Townsend RR, Hardy MR, Longren J, Arnarp J, Haraldsson M, Lonn H. Binding of synthetic oligosaccharides to the hepatic Gal/GalNAC lectin. Dependence on fine structural features. J Biol Chem 1983;258:199-202.
54. Hayashi K, Dojo S, Hirata Y, Othani H, Nakashima K, Nishio E, Kurushima H, Saeki M, Kajiyama G. Metabolic changes in LDL receptors and an appearance of scavenger receptors after phorbol-ester induced differentiation of U937 cells. Biochim Biophys Acta 1991;1082:152-160.
55. Russell ME, Utans U, Wallace AF, Liang P, Areci RJ, Karnovsky MJ, Wyner LR, Yamashita Y, Tarn C. Identification and upregulation of galactose/N-acetylgalactosamine macrophage lectin in rat cardiac allografts with arteriosclerosis. J Clin Invest 1994;94:722-730.