Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly

Journal of Biological Chemistry

Volumn 290, Issue 5, 2015, Pages 2769-2783

  Ednie, Andrew R ^a   Bennett, Eric S ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX NETWORKS; ELECTRIC RECTIFIERS; HEART; MAMMALS; PATHOLOGY;

ACTION POTENTIAL DURATIONS; CONGENITAL DISORDERS; DELAYED RECTIFIER; MAXIMUM CURRENT DENSITY; PATHOLOGIC CONDITIONS; PROTEIN EXPRESSION LEVELS; SIALYLTRANSFERASE; VENTRICULAR REPOLARIZATION;

GLYCOSYLATION;

DELAYED RECTIFIER POTASSIUM CHANNEL; GLYCOGEN; POLYSIALIC ACID; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV1.5; POTASSIUM CHANNEL KV2.1; POTASSIUM CHANNEL KV4.2; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; BETA-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE; ISOPROTEIN; SHAL POTASSIUM CHANNEL; SIALYLTRANSFERASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIAC TRANSIENT OUTWARD POTASSIUM CURRENT; CELL LABELING; CELLULAR PARAMETERS; CHANNEL GATING; CONTROLLED STUDY; GENE; GENE DELETION; GENE PRODUCT; HEART DEPOLARIZATION; HEART FUNCTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE EXCITABILITY; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; MALE; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QT INTERVAL; SIALYLATION; ST3GAL4 GENE; ACTION POTENTIAL; ANIMAL; ELECTROPHYSIOLOGY; GENETICS; METABOLISM; MUSCLE CELL; PHYSIOLOGY;

MUS;

ACTION POTENTIALS; ANIMALS; ELECTROPHYSIOLOGY; KV1.5 POTASSIUM CHANNEL; MICE; MUSCLE CELLS; MYOCYTES, CARDIAC; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN ISOFORMS; SHAL POTASSIUM CHANNELS; SIALYLTRANSFERASES;

EID: 84921931491     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.605139     Document Type: Article

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