Human serum N-glycan profiles are age and sex dependent

Age and Ageing

Volumn 40, Issue 5, 2011, Pages 568-575

  Ding, Ning ^a   Sun, Huan Nie ^a   Sun, Wei ^a   Qu, Youpeng ^a   Liu, Xia ^a   Yao, Yuanfei ^a   Liang, Xue ^a   Chen, Cuiying Chitty ^b   Li, Yu ^a  

^a HARBIN INSTITUTE OF TECHNOLOGY   (China)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Ageing; DSA FACE; Gender; N glycan

Indexed keywords

GLYCAN DERIVATIVE;

ADULT; AGE; AGING; ARTICLE; CARBOHYDRATE ANALYSIS; CHINESE; COMPUTER PROGRAM; ELECTROPHORESIS; FEMALE; FUCOSYLATION; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; SEX DIFFERENCE; VOLUNTEER;

ACETYLGLUCOSAMINE; ADULT; AGE DISTRIBUTION; AGE FACTORS; AGING; BIOLOGICAL MARKERS; CHINA; ELECTROPHORESIS; FEMALE; FUCOSE; GLYCOMICS; GLYCOSYLATION; HUMANS; MALE; MIDDLE AGED; POLYSACCHARIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEX DISTRIBUTION; SEX FACTORS;

EID: 80051724652     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afr084     Document Type: Article

References (30)

1. Hayflick L. Biological aging is no longer an unsolved problem. Ann N Y Acad Sci 2007; 1100: 1-13.
2. Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell 2005; 120: 449-60.
3. Kronenberg F. Genome-wide association studies in aging-related processes such as diabetes mellitus, atherosclerosis and cancer. Exp Gerontol 2008; 43: 39-43.
4. Troen BR. The biology of aging. Mt Sinai J Med 2003; 70: 3-22.
5. Sprott RL. Biomarkers of aging and disease: introduction and definitions. Exp Gerontol 2010; 45: 2-4.
6. Crimmins E, Vasunilashorn S, Kim JK et al. Biomarkers related to aging in human populations. Adv Clin Chem 2008; 46: 161-216.
7. Wizemann TM, Pardue ML. Exploring the Biological Contribution to Human Health: Does Sex Matter? Washington, DC: National Academy Press, 2001.
8. Ratner DM, Adams EW, Disney MD et al. Tools for glycomics: mapping interactions of carbohydrates in biological systems. Chembiochem 2004; 5: 1375-83.
9. Freeze HH, Aebi M. Altered glycan structures: the molecular basis of congenital disorders of glycosylation. Curr Opin Struct Biol 2005; 15: 490-8.
10. Comelli EM, Head SR, Gilmartin T et al. A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology 2006; 16: 117-31.
11. Byerley LO, Leamy L, Tam SW et al. Development of a serum profile for healthy aging. Age 2010; 32: 497-507.
12. Vanhooren V, Liu XE, Franceschi C et al. N-glycan profiles as tools in diagnosis of hepatocellular carcinoma and prediction of healthy human ageing. Mech Ageing Dev 2009; 130: 92-7.
13. Vanhooren V, Laroy W, Libert C et al. N-Glycan profiling in the study of human aging. Biogerontology 2008; 9: 351-6.
14. Liu XE, Desmyter L, Gao CF et al. N-glycomic changes in hepatocellular carcinoma patients with liver cirrhosis induced by hepatitis B virus. Hepatology 2007; 46: 1426-35.
15. Trombetta ES, Parodi AJ. Glycoprotein reglucosylation. Methods 2005; 35: 328-37.
16. Dwek RA. Biological importance of glycosylation. Dev Biol Stand 1998; 96: 43-7.
17. Lau KS, Partridge EA, Grigorian A et al. Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. Cell 2007; 129: 123-34.
18. Vanhooren V, Dewaele S, Libert C et al. Serum N-glycan profile shift during human ageing. Exp Gerontol 2010; 45: 738-43.
19. Pucic M, Pinto S, Novokmet M et al. Common aberrations from the normal human plasma N-glycan profile. Glycobiology 2010; 20: 970-5.
20. Ruhaak LR, Uh HW, Beekman M et al. Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health. J Proteome Res 2010 Dec 24 [Epub ahead of print].
21. Knezevic A, Gornik O, Polasek O et al. Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans. Glycobiology 2010; 20: 959-69.
22. Stanta JL, Saldova R, Struwe WB et al. Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia. J Proteome Res 2010; 9: 4476-89.
23. Staudacher E, Altmann F, Wilson IB et al. Fucose in N-glycans: from plant to man. Biochim Biophys Acta 1999; 1473: 216-36.
24. Naugler WE, Sakurai T, Kim S et al. Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 2007; 317: 121-4.
25. Bosch FX, Ribes J, Diaz M et al. Primary liver cancer: worldwide incidence and trends. Gastroenterology 2004; 127 (Suppl. 1): S5-16.
26. Lynch HT, Schuelke GS, Wells IC et al. Hereditary orarian carcinoma Biomarker studies. Cancer 1985; 55: 410-l5.
27. Yarema KJ, Bertozzi CR. Characterizing glycosylation pathways. Genome Biol 2001; 2: reviews0004.1â reviews0004.10.
28. Lee BY, Han JA, Im JS et al. Senescence-associated betagalactosidase is lysosomal beta-galactosidase. Aging Cell 2006; 5: 187-95.
29. Toussaint O, Dumont P, Dierick JF et al. Stress-induced premature senescence. Essence of life, evolution, stress, and aging. Ann N Y Acad Sci 2000; 908: 85-98.
30. Ruhaak LR, Uh HW, Beekman M et al. Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity. PLoS One 2010; 5: e12566.