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Volumn 2018, Issue 134, 2018, Pages

The Lambda select cii mutation detection system

Author keywords

Bacteriophage; CII transgene; Embryonic mouse fibroblasts; EMF; Immunology and infection; Issue 134; Mutation; Shuttle vector

Indexed keywords

TRANSCRIPTION FACTOR; VIRAL PROTEIN;

EID: 85046631407     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/57510     Document Type: Article
Times cited : (3)

References (78)
  • 1
    • 0029810641 scopus 로고    scopus 로고
    • Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target
    • Jakubczak, J. L. et al. Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target. Proc Natl Acad Sci U S A. 93 (17), 9073-9078 (1996).
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.17 , pp. 9073-9078
    • Jakubczak, J.L.1
  • 2
    • 23744463885 scopus 로고    scopus 로고
    • Detailed review of transgenic rodent mutation assays
    • Lambert, I. B., Singer, T. M., Boucher, S. E., & Douglas, G. R. Detailed review of transgenic rodent mutation assays. Mutat Res. 590 (1-3), 1-280 (2005).
    • (2005) Mutat Res , vol.590 , Issue.1-3 , pp. 1-280
    • Lambert, I.B.1    Singer, T.M.2    Boucher, S.E.3    Douglas, G.R.4
  • 3
    • 33747874880 scopus 로고    scopus 로고
    • Investigating human cancer etiology by DNA lesion footprinting and mutagenicity analysis
    • Besaratinia, A., & Pfeifer, G. P. Investigating human cancer etiology by DNA lesion footprinting and mutagenicity analysis. Carcinogenesis. 27 (8), 1526-1537 (2006).
    • (2006) Carcinogenesis , vol.27 , Issue.8 , pp. 1526-1537
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 4
    • 0031670587 scopus 로고    scopus 로고
    • Spontaneous and ENU-induced mutation spectra at the cII locus in Big Blue Rat2 embryonic fibroblasts
    • Watson, D. E., Cunningham, M. L., & Tindall, K. R. Spontaneous and ENU-induced mutation spectra at the cII locus in Big Blue Rat2 embryonic fibroblasts. Mutagenesis. 13 (5), 487-497 (1998).
    • (1998) Mutagenesis , vol.13 , Issue.5 , pp. 487-497
    • Watson, D.E.1    Cunningham, M.L.2    Tindall, K.R.3
  • 5
    • 0032749587 scopus 로고    scopus 로고
    • Characterization of new transgenic Big Blue(R) mouse and rat primary fibroblast cell strains for use in molecular toxicology studies
    • Erexson, G. L., Watson, D. E., & Tindall, K. R. Characterization of new transgenic Big Blue(R) mouse and rat primary fibroblast cell strains for use in molecular toxicology studies. Environ Mol Mutagen. 34 (2-3), 90-96 (1999).
    • (1999) Environ Mol Mutagen , vol.34 , Issue.2-3 , pp. 90-96
    • Erexson, G.L.1    Watson, D.E.2    Tindall, K.R.3
  • 6
    • 0034695032 scopus 로고    scopus 로고
    • Micronuclei and gene mutations in transgenic big Blue((R)) mouse and rat fibroblasts after exposure to the epoxide metabolites of 1, 3-butadiene
    • Erexson, G. L., & Tindall, K. R. Micronuclei and gene mutations in transgenic big Blue((R)) mouse and rat fibroblasts after exposure to the epoxide metabolites of 1, 3-butadiene. Mutat Res. 472 (1-2), 105-117 (2000).
    • (2000) Mutat Res , vol.472 , Issue.1-2 , pp. 105-117
    • Erexson, G.L.1    Tindall, K.R.2
  • 7
    • 0036207610 scopus 로고    scopus 로고
    • 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mutagenesis in cultured Big Blue rat mammary epithelial and fibroblast cells
    • McDiarmid, H. M., Douglas, G. R., Coomber, B. L., & Josephy, P. D. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mutagenesis in cultured Big Blue rat mammary epithelial and fibroblast cells. Environ Mol Mutagen. 39 (2-3), 245-253 (2002).
    • (2002) Environ Mol Mutagen , vol.39 , Issue.2-3 , pp. 245-253
    • McDiarmid, H.M.1    Douglas, G.R.2    Coomber, B.L.3    Josephy, P.D.4
  • 8
    • 0037469392 scopus 로고    scopus 로고
    • Mutagenicity of the oral carcinogen 4-nitroquinoline-1-oxide in cultured BigBlue rat tongue epithelial cells and fibroblasts
    • Papp-Szabo, E., Douglas, G. R., Coomber, B. L., & Josephy, P. D. Mutagenicity of the oral carcinogen 4-nitroquinoline-1-oxide in cultured BigBlue rat tongue epithelial cells and fibroblasts. Mutat Res. 522 (1-2), 107-117 (2003).
    • (2003) Mutat Res , vol.522 , Issue.1-2 , pp. 107-117
    • Papp-Szabo, E.1    Douglas, G.R.2    Coomber, B.L.3    Josephy, P.D.4
  • 9
    • 77954594695 scopus 로고    scopus 로고
    • In Vitro Study of Mutagenesis Induced by Crocidolite-Exposed Alveolar Macrophages NR8383 in Cocultured Big Blue Rat2 Embryonic Fibroblasts
    • Guichard, Y. et al. In Vitro Study of Mutagenesis Induced by Crocidolite-Exposed Alveolar Macrophages NR8383 in Cocultured Big Blue Rat2 Embryonic Fibroblasts. J Toxicol. 2010 323828 (2010).
    • (2010) J Toxicol , vol.2010 , pp. 323828
    • Guichard, Y.1
  • 10
    • 0036682285 scopus 로고    scopus 로고
    • Mutational signature of the proximate bladder carcinogen N-hydroxy-4-acetylaminobiphenyl: Inconsistency with the p53 mutational spectrum in bladder cancer
    • Besaratinia, A., Bates, S. E., & Pfeifer, G. P. Mutational signature of the proximate bladder carcinogen N-hydroxy-4-acetylaminobiphenyl: inconsistency with the p53 mutational spectrum in bladder cancer. Cancer Res. 62 (15), 4331-4338 (2002).
    • (2002) Cancer Res , vol.62 , Issue.15 , pp. 4331-4338
    • Besaratinia, A.1    Bates, S.E.2    Pfeifer, G.P.3
  • 11
    • 0346059599 scopus 로고    scopus 로고
    • Enhancement of the mutagenicity of benzo(A)pyrene diol epoxide by a nonmutagenic dose of ultraviolet A radiation
    • Besaratinia, A., & Pfeifer, G. P. Enhancement of the mutagenicity of benzo(a)pyrene diol epoxide by a nonmutagenic dose of ultraviolet A radiation. Cancer Res. 63 (24), 8708-8716 (2003).
    • (2003) Cancer Res , vol.63 , Issue.24 , pp. 8708-8716
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 12
    • 0037938687 scopus 로고    scopus 로고
    • Weak yet distinct mutagenicity of acrylamide in mammalian cells
    • Besaratinia, A., & Pfeifer, G. P. Weak yet distinct mutagenicity of acrylamide in mammalian cells. J Natl Cancer Inst. 95 (12), 889-896 (2003).
    • (2003) J Natl Cancer Inst , vol.95 , Issue.12 , pp. 889-896
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 13
    • 9744256243 scopus 로고    scopus 로고
    • Biological consequences of 8-methoxypsoralen-photoinduced lesions: Sequence-specificity of mutations and preponderance of T to C and T to a mutations
    • Besaratinia, A., & Pfeifer, G. P. Biological consequences of 8-methoxypsoralen-photoinduced lesions: sequence-specificity of mutations and preponderance of T to C and T to a mutations. J Invest Dermatol. 123 (6), 1140-1146 (2004).
    • (2004) J Invest Dermatol , vol.123 , Issue.6 , pp. 1140-1146
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 14
    • 3242690880 scopus 로고    scopus 로고
    • Genotoxicity of acrylamide and glycidamide
    • Besaratinia, A., & Pfeifer, G. P. Genotoxicity of acrylamide and glycidamide. J Natl Cancer Inst. 96 (13), 1023-1029 (2004).
    • (2004) J Natl Cancer Inst , vol.96 , Issue.13 , pp. 1023-1029
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 15
    • 10644237978 scopus 로고    scopus 로고
    • Similar mutagenicity of photoactivated porphyrins and ultraviolet A radiation in mouse embryonic fibroblasts: Involvement of oxidative DNA lesions in mutagenesis
    • Besaratinia, A., Bates, S. E., Synold, T. W., & Pfeifer, G. P. Similar mutagenicity of photoactivated porphyrins and ultraviolet A radiation in mouse embryonic fibroblasts: involvement of oxidative DNA lesions in mutagenesis. Biochemistry. 43 (49), 15557-15566 (2004).
    • (2004) Biochemistry , vol.43 , Issue.49 , pp. 15557-15566
    • Besaratinia, A.1    Bates, S.E.2    Synold, T.W.3    Pfeifer, G.P.4
  • 16
    • 5644278860 scopus 로고    scopus 로고
    • DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells
    • Yoon, J. H. et al. DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells. Cancer Res. 64 (20), 7321-7328 (2004).
    • (2004) Cancer Res , vol.64 , Issue.20 , pp. 7321-7328
    • Yoon, J.H.1
  • 17
    • 3042519214 scopus 로고    scopus 로고
    • G-to-T transversions and small tandem base deletions are the hallmark of mutations induced by ultraviolet a radiation in mammalian cells
    • Besaratinia, A., Synold, T. W., Xi, B., & Pfeifer, G. P. G-to-T transversions and small tandem base deletions are the hallmark of mutations induced by ultraviolet a radiation in mammalian cells. Biochemistry. 43 (25), 8169-8177 (2004).
    • (2004) Biochemistry , vol.43 , Issue.25 , pp. 8169-8177
    • Besaratinia, A.1    Synold, T.W.2    Xi, B.3    Pfeifer, G.P.4
  • 18
    • 20444370676 scopus 로고    scopus 로고
    • Investigating DNA adduct-targeted mutagenicity of tamoxifen: Preferential formation of tamoxifen-DNA adducts in the human p53 gene in SV40 immortalized hepatocytes but not endometrial carcinoma cells
    • Besaratinia, A., & Pfeifer, G. P. Investigating DNA adduct-targeted mutagenicity of tamoxifen: preferential formation of tamoxifen-DNA adducts in the human p53 gene in SV40 immortalized hepatocytes but not endometrial carcinoma cells. Biochemistry. 44 (23), 8418-8427 (2005).
    • (2005) Biochemistry , vol.44 , Issue.23 , pp. 8418-8427
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 19
    • 37549053570 scopus 로고    scopus 로고
    • Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells
    • Kim, S. I., Pfeifer, G. P., & Besaratinia, A. Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells. Cancer Res. 67 (24), 11640-11647 (2007).
    • (2007) Cancer Res , vol.67 , Issue.24 , pp. 11640-11647
    • Kim, S.I.1    Pfeifer, G.P.2    Besaratinia, A.3
  • 20
    • 34347226353 scopus 로고    scopus 로고
    • Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C
    • Besaratinia, A., Kim, S. I., Bates, S. E., & Pfeifer, G. P. Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C. Proc Natl Acad Sci U S A. 104 (14), 5953-5958 (2007).
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.14 , pp. 5953-5958
    • Besaratinia, A.1    Kim, S.I.2    Bates, S.E.3    Pfeifer, G.P.4
  • 21
    • 46749087013 scopus 로고    scopus 로고
    • Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cells
    • Besaratinia, A., Kim, S. I., & Pfeifer, G. P. Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cells. FASEB J. 22 (7), 2379-2392 (2008).
    • (2008) FASEB J , vol.22 , Issue.7 , pp. 2379-2392
    • Besaratinia, A.1    Kim, S.I.2    Pfeifer, G.P.3
  • 22
    • 69249129569 scopus 로고    scopus 로고
    • Vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure
    • Besaratinia, A., Kim, S. I., Hainaut, P., & Pfeifer, G. P. In Vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure. Gastroenterology. 137 (3), 1127-1137, 1137 e1121-1125 (2009).
    • (2009) Gastroenterology , vol.137 , Issue.3
    • Besaratinia, A.1    Kim, S.I.2    Hainaut, P.3    Pfeifer, G.P.4
  • 23
    • 84867288246 scopus 로고    scopus 로고
    • A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens
    • Besaratinia, A. et al. A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens. Nucleic Acids Res. 40 (15), e116 (2012).
    • (2012) Nucleic Acids Res , vol.40 , Issue.15
    • Besaratinia, A.1
  • 24
    • 85026921763 scopus 로고    scopus 로고
    • Limited mutagenicity of electronic cigarettes in mouse or human cells in vitro
    • Tommasi, S., Bates, S. E., Behar, R. Z., Talbot, P., & Besaratinia, A. Limited mutagenicity of electronic cigarettes in mouse or human cells in vitro. Lung Cancer. 112 41-46 (2017).
    • (2017) Lung Cancer , vol.112 , pp. 41-46
    • Tommasi, S.1    Bates, S.E.2    Behar, R.Z.3    Talbot, P.4    Besaratinia, A.5
  • 25
    • 0028230888 scopus 로고
    • The use of shuttle vectors for mutation analysis in transgenic mice and rats
    • Dycaico, M. J. et al. The use of shuttle vectors for mutation analysis in transgenic mice and rats. Mutat Res. 307 (2), 461-478 (1994).
    • (1994) Mutat Res , vol.307 , Issue.2 , pp. 461-478
    • Dycaico, M.J.1
  • 26
    • 0030345886 scopus 로고    scopus 로고
    • Mutational spectra of tamoxifen-induced mutations in the livers of lacI transgenic rats
    • Davies, R. et al. Mutational spectra of tamoxifen-induced mutations in the livers of lacI transgenic rats. Environ Mol Mutagen. 28 (4), 430-433 (1996).
    • (1996) Environ Mol Mutagen , vol.28 , Issue.4 , pp. 430-433
    • Davies, R.1
  • 27
    • 0030781051 scopus 로고    scopus 로고
    • Spectrum of spontaneous mutations in liver tissue of lacI transgenic mice
    • de Boer, J. G. et al. Spectrum of spontaneous mutations in liver tissue of lacI transgenic mice. Environ Mol Mutagen. 30 (3), 273-286 (1997).
    • (1997) Environ Mol Mutagen , vol.30 , Issue.3 , pp. 273-286
    • de Boer, J.G.1
  • 28
    • 0030329708 scopus 로고    scopus 로고
    • Spectrum of mutations in kidney, stomach, and liver from lacI transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate
    • de Boer, J. G., Mirsalis, J. C., Provost, G. S., Tindall, K. R., & Glickman, B. W. Spectrum of mutations in kidney, stomach, and liver from lacI transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate. Environ Mol Mutagen. 28 (4), 418-423 (1996).
    • (1996) Environ Mol Mutagen , vol.28 , Issue.4 , pp. 418-423
    • de Boer, J.G.1    Mirsalis, J.C.2    Provost, G.S.3    Tindall, K.R.4    Glickman, B.W.5
  • 29
    • 0029822465 scopus 로고    scopus 로고
    • Species-specific differences in hepatic mutant frequency and mutational spectrum among lambda/lacI transgenic rats and mice following exposure to aflatoxin B1
    • Dycaico, M. J. et al. Species-specific differences in hepatic mutant frequency and mutational spectrum among lambda/lacI transgenic rats and mice following exposure to aflatoxin B1. Carcinogenesis. 17 (11), 2347-2356 (1996).
    • (1996) Carcinogenesis , vol.17 , Issue.11 , pp. 2347-2356
    • Dycaico, M.J.1
  • 30
    • 0028991066 scopus 로고
    • Relative sensitivity of the endogenous hprt gene and lacI transgene in ENU-treated Big Blue B6C3F1 mice
    • Skopek, T. R., Kort, K. L., & Marino, D. R. Relative sensitivity of the endogenous hprt gene and lacI transgene in ENU-treated Big Blue B6C3F1 mice. Environ Mol Mutagen. 26 (1), 9-15 (1995).
    • (1995) Environ Mol Mutagen , vol.26 , Issue.1 , pp. 9-15
    • Skopek, T.R.1    Kort, K.L.2    Marino, D.R.3
  • 31
    • 0030344674 scopus 로고    scopus 로고
    • Mutagenic response of the endogenous hprt gene and lacI transgene in benzo[a]pyrene-treated Big Blue B6C3F1 mice
    • Skopek, T. R. et al. Mutagenic response of the endogenous hprt gene and lacI transgene in benzo[a]pyrene-treated Big Blue B6C3F1 mice. Environ Mol Mutagen. 28 (4), 376-384 (1996).
    • (1996) Environ Mol Mutagen , vol.28 , Issue.4 , pp. 376-384
    • Skopek, T.R.1
  • 32
    • 0030329503 scopus 로고    scopus 로고
    • An efficient laboratory protocol for the sequencing of large numbers of lacI mutants recovered from Big Blue transgenic animals
    • Erfle, H. L. et al. An efficient laboratory protocol for the sequencing of large numbers of lacI mutants recovered from Big Blue transgenic animals. Environ Mol Mutagen. 28 (4), 393-396 (1996).
    • (1996) Environ Mol Mutagen , vol.28 , Issue.4 , pp. 393-396
    • Erfle, H.L.1
  • 33
    • 0028213991 scopus 로고
    • Development of a lambda-based complementation assay for the preliminary localization of lacI mutants from the Big Blue mouse: Implications for a DNA-sequencing strategy
    • Gu, M., Ahmed, A., Wei, C., Gorelick, N., & Glickman, B. W. Development of a lambda-based complementation assay for the preliminary localization of lacI mutants from the Big Blue mouse: implications for a DNA-sequencing strategy. Mutat Res. 307 (2), 533-540 (1994).
    • (1994) Mutat Res , vol.307 , Issue.2 , pp. 533-540
    • Gu, M.1    Ahmed, A.2    Wei, C.3    Gorelick, N.4    Glickman, B.W.5
  • 34
    • 0032937876 scopus 로고    scopus 로고
    • Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice
    • Harbach, P. R., Zimmer, D. M., Filipunas, A. L., Mattes, W. B., & Aaron, C. S. Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice. Environ Mol Mutagen. 33 (2), 132-143 (1999).
    • (1999) Environ Mol Mutagen , vol.33 , Issue.2 , pp. 132-143
    • Harbach, P.R.1    Zimmer, D.M.2    Filipunas, A.L.3    Mattes, W.B.4    Aaron, C.S.5
  • 35
    • 0025779567 scopus 로고
    • Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice
    • Kohler, S. W. et al. Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice. Proc Natl Acad Sci U S A. 88 (18), 7958-7962 (1991).
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.18 , pp. 7958-7962
    • Kohler, S.W.1
  • 36
    • 0031956950 scopus 로고    scopus 로고
    • Comparison of the types of mutations induced by 7,12-dimethylbenz[a]anthracene in the lacI and hprt genes of Big Blue rats
    • Mittelstaedt, R. A. et al. Comparison of the types of mutations induced by 7,12-dimethylbenz[a]anthracene in the lacI and hprt genes of Big Blue rats. Environ Mol Mutagen. 31 (2), 149-156 (1998).
    • (1998) Environ Mol Mutagen , vol.31 , Issue.2 , pp. 149-156
    • Mittelstaedt, R.A.1
  • 37
    • 0032511836 scopus 로고    scopus 로고
    • A comparative study of in vivo mutation assays: Analysis of hprt, lacI, cII/ cI and as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue mice
    • Monroe, J. J., Kort, K. L., Miller, J. E., Marino, D. R., & Skopek, T. R. A comparative study of in vivo mutation assays: analysis of hprt, lacI, cII/ cI and as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue mice. Mutat Res. 421 (1), 121-136 (1998).
    • (1998) Mutat Res , vol.421 , Issue.1 , pp. 121-136
    • Monroe, J.J.1    Kort, K.L.2    Miller, J.E.3    Marino, D.R.4    Skopek, T.R.5
  • 38
    • 0028178048 scopus 로고
    • A preliminary evaluation of the performance of the Muta Mouse (LacZ) and Big Blue (lacI) transgenic mouse mutation assays
    • Morrison, V., & Ashby, J. A preliminary evaluation of the performance of the Muta Mouse (lacZ) and Big Blue (lacI) transgenic mouse mutation assays. Mutagenesis. 9 (4), 367-375 (1994).
    • (1994) Mutagenesis , vol.9 , Issue.4 , pp. 367-375
    • Morrison, V.1    Ashby, J.2
  • 39
    • 6844261154 scopus 로고    scopus 로고
    • Agreement of mutational characteristics of heterocyclic amines in lacI of the Big Blue mouse with those in tumor related genes in rodents
    • Okonogi, H. et al. Agreement of mutational characteristics of heterocyclic amines in lacI of the Big Blue mouse with those in tumor related genes in rodents. Carcinogenesis. 18 (4), 745-748 (1997).
    • (1997) Carcinogenesis , vol.18 , Issue.4 , pp. 745-748
    • Okonogi, H.1
  • 40
    • 0030329356 scopus 로고    scopus 로고
    • Mutagenic response to benzene and tris(2,3-dibromopropyl)-phosphate in the lambda lacI transgenic mouse mutation assay: A standardized approach to in vivo mutation analysis
    • Provost, G. S., Mirsalis, J. C., Rogers, B. J., & Short, J. M. Mutagenic response to benzene and tris(2,3-dibromopropyl)-phosphate in the lambda lacI transgenic mouse mutation assay: a standardized approach to in vivo mutation analysis. Environ Mol Mutagen. 28 (4), 342-347 (1996).
    • (1996) Environ Mol Mutagen , vol.28 , Issue.4 , pp. 342-347
    • Provost, G.S.1    Mirsalis, J.C.2    Rogers, B.J.3    Short, J.M.4
  • 41
    • 0034052578 scopus 로고    scopus 로고
    • LacI mutation spectra following benzo[a]pyrene treatment of Big Blue mice
    • Shane, B. S. et al. LacI mutation spectra following benzo[a]pyrene treatment of Big Blue mice. Carcinogenesis. 21 (4), 715-725 (2000).
    • (2000) Carcinogenesis , vol.21 , Issue.4 , pp. 715-725
    • Shane, B.S.1
  • 42
    • 0030914357 scopus 로고    scopus 로고
    • Mutant frequency of lacI in transgenic mice following benzo[a]pyrene treatment and partial hepatectomy
    • Shane, B. S., Lockhart, A. M., Winston, G. W., & Tindall, K. R. Mutant frequency of lacI in transgenic mice following benzo[a]pyrene treatment and partial hepatectomy. Mutat Res. 377 (1), 1-11 (1997).
    • (1997) Mutat Res , vol.377 , Issue.1 , pp. 1-11
    • Shane, B.S.1    Lockhart, A.M.2    Winston, G.W.3    Tindall, K.R.4
  • 43
    • 0027311053 scopus 로고
    • Mutations in liver DNA of lacI transgenic mice (Big Blue) following subchronic exposure to 2-acetylaminofluorene
    • Shephard, S. E., Sengstag, C., Lutz, W. K., & Schlatter, C. Mutations in liver DNA of lacI transgenic mice (Big Blue) following subchronic exposure to 2-acetylaminofluorene. Mutat Res. 302 (2), 91-96 (1993).
    • (1993) Mutat Res , vol.302 , Issue.2 , pp. 91-96
    • Shephard, S.E.1    Sengstag, C.2    Lutz, W.K.3    Schlatter, C.4
  • 44
    • 0027375228 scopus 로고
    • Big Blue transgenic mouse lacI mutation analysis
    • Stiegler, G. L., & Stillwell, L. C. Big Blue transgenic mouse lacI mutation analysis. Environ Mol Mutagen. 22 (3), 127-129 (1993).
    • (1993) Environ Mol Mutagen , vol.22 , Issue.3 , pp. 127-129
    • Stiegler, G.L.1    Stillwell, L.C.2
  • 45
    • 0029821901 scopus 로고    scopus 로고
    • Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice
    • Walker, V. E. et al. Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice. Cancer Res. 56 (20), 4654-4661 (1996).
    • (1996) Cancer Res , vol.56 , Issue.20 , pp. 4654-4661
    • Walker, V.E.1
  • 46
    • 0028930775 scopus 로고
    • Interlaboratory comparison: Liver spontaneous mutant frequency from lambda/lacI transgenic mice (Big Blue) (II)
    • Young, R. R., Rogers, B. J., Provost, G. S., Short, J. M., & Putman, D. L. Interlaboratory comparison: liver spontaneous mutant frequency from lambda/lacI transgenic mice (Big Blue) (II). Mutat Res. 327 (1-2), 67-73 (1995).
    • (1995) Mutat Res , vol.327 , Issue.1-2 , pp. 67-73
    • Young, R.R.1    Rogers, B.J.2    Provost, G.S.3    Short, J.M.4    Putman, D.L.5
  • 47
    • 0030344383 scopus 로고    scopus 로고
    • Spontaneous and ethylnitrosourea-induced mutation fixation and molecular spectra at the lacI transgene in the Big Blue rat-2 embryo cell line
    • Zimmer, D. M., Zhang, X. B., Harbach, P. R., Mayo, J. K., & Aaron, C. S. Spontaneous and ethylnitrosourea-induced mutation fixation and molecular spectra at the lacI transgene in the Big Blue rat-2 embryo cell line. Environ Mol Mutagen. 28 (4), 325-333 (1996).
    • (1996) Environ Mol Mutagen , vol.28 , Issue.4 , pp. 325-333
    • Zimmer, D.M.1    Zhang, X.B.2    Harbach, P.R.3    Mayo, J.K.4    Aaron, C.S.5
  • 48
    • 0032589724 scopus 로고    scopus 로고
    • The cII locus in the MutaMouse system
    • Swiger, R. R. et al. The cII locus in the MutaMouse system. Environ Mol Mutagen. 34 (2-3), 201-207 (1999).
    • (1999) Environ Mol Mutagen , vol.34 , Issue.2-3 , pp. 201-207
    • Swiger, R.R.1
  • 49
    • 0037255626 scopus 로고    scopus 로고
    • Treatment and sampling protocols for transgenic mutation assays
    • Heddle, J. A., Martus, H. J., & Douglas, G. R. Treatment and sampling protocols for transgenic mutation assays. Environ Mol Mutagen. 41 (1), 1-6 (2003).
    • (2003) Environ Mol Mutagen , vol.41 , Issue.1 , pp. 1-6
    • Heddle, J.A.1    Martus, H.J.2    Douglas, G.R.3
  • 50
    • 0141785156 scopus 로고    scopus 로고
    • In vivo transgenic mutation assays
    • Thybaud, V. et al. In vivo transgenic mutation assays. Mutat Res. 540 (2), 141-151 (2003).
    • (2003) Mutat Res , vol.540 , Issue.2 , pp. 141-151
    • Thybaud, V.1
  • 52
    • 84908504436 scopus 로고    scopus 로고
    • Quantifying in vivo somatic mutations using transgenic mouse model systems
    • Swiger, R. R. Quantifying in vivo somatic mutations using transgenic mouse model systems. Methods Mol Biol. 1105 271-282 (2014).
    • (2014) Methods Mol Biol , vol.1105 , pp. 271-282
    • Swiger, R.R.1
  • 53
    • 79951515601 scopus 로고    scopus 로고
    • Loss of Rassf1a enhances p53-mediated tumor predisposition and accelerates progression to aneuploidy
    • Tommasi, S., Besaratinia, A., Wilczynski, S. P., & Pfeifer, G. P. Loss of Rassf1a enhances p53-mediated tumor predisposition and accelerates progression to aneuploidy. Oncogene. 30 (6), 690-700 (2011).
    • (2011) Oncogene , vol.30 , Issue.6 , pp. 690-700
    • Tommasi, S.1    Besaratinia, A.2    Wilczynski, S.P.3    Pfeifer, G.P.4
  • 55
    • 0024076658 scopus 로고
    • Tissue-specific and steroid-dependent interaction of transcription factors with the oestrogen-inducible apoVLDL II promoter in vivo
    • Wijnholds, J., Philipsen, J. N., & Ab, G. Tissue-specific and steroid-dependent interaction of transcription factors with the oestrogen-inducible apoVLDL II promoter in vivo. EMBO J. 7 (9), 2757-2763 (1988).
    • (1988) EMBO J , vol.7 , Issue.9 , pp. 2757-2763
    • Wijnholds, J.1    Philipsen, J.N.2    Ab, G.3
  • 57
    • 0023264512 scopus 로고
    • Statistical test for the comparison of samples from mutational spectra
    • Adams, W. T., & Skopek, T. R. Statistical test for the comparison of samples from mutational spectra. J Mol Biol. 194 (3), 391-396 (1987).
    • (1987) J Mol Biol , vol.194 , Issue.3 , pp. 391-396
    • Adams, W.T.1    Skopek, T.R.2
  • 58
    • 84860893339 scopus 로고    scopus 로고
    • New experimental data linking secondhand smoke exposure to lung cancer in nonsmokers
    • Kim, S. I., Yoon, J. I., Tommasi, S., & Besaratinia, A. New experimental data linking secondhand smoke exposure to lung cancer in nonsmokers. FASEB J. 26 (5), 1845-1854 (2012).
    • (2012) FASEB J , vol.26 , Issue.5 , pp. 1845-1854
    • Kim, S.I.1    Yoon, J.I.2    Tommasi, S.3    Besaratinia, A.4
  • 59
    • 84863229172 scopus 로고    scopus 로고
    • Organ specificity of the bladder carcinogen 4-aminobiphenyl in inducing DNA damage and mutation in mice
    • Yoon, J. I., Kim, S. I., Tommasi, S., & Besaratinia, A. Organ specificity of the bladder carcinogen 4-aminobiphenyl in inducing DNA damage and mutation in mice. Cancer Prev Res (Phila). 5 (2), 299-308 (2012).
    • (2012) Cancer Prev Res (Phila) , vol.5 , Issue.2 , pp. 299-308
    • Yoon, J.I.1    Kim, S.I.2    Tommasi, S.3    Besaratinia, A.4
  • 60
    • 10844241185 scopus 로고    scopus 로고
    • Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene
    • Boyiri, T. et al. Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene. Carcinogenesis. 25 (4), 637-643 (2004).
    • (2004) Carcinogenesis , vol.25 , Issue.4 , pp. 637-643
    • Boyiri, T.1
  • 61
    • 0036798839 scopus 로고    scopus 로고
    • Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats
    • Chen, T. et al. Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats. Carcinogenesis. 23 (10), 1751-1757 (2002).
    • (2002) Carcinogenesis , vol.23 , Issue.10 , pp. 1751-1757
    • Chen, T.1
  • 62
    • 25444507227 scopus 로고    scopus 로고
    • 4-Aminobiphenyl induces liver DNA adducts in both neonatal and adult mice but induces liver mutations only in neonatal mice
    • Chen, T. et al. 4-Aminobiphenyl induces liver DNA adducts in both neonatal and adult mice but induces liver mutations only in neonatal mice. Int J Cancer. 117 (2), 182-187 (2005).
    • (2005) Int J Cancer , vol.117 , Issue.2 , pp. 182-187
    • Chen, T.1
  • 63
    • 77956175629 scopus 로고    scopus 로고
    • Heart tissue of harlequin (Hq)/Big Blue mice has elevated reactive oxygen species without significant impact on the frequency and nature of point mutations in nuclear DNA
    • Crabbe, R. A., & Hill, K. A. Heart tissue of harlequin (hq)/Big Blue mice has elevated reactive oxygen species without significant impact on the frequency and nature of point mutations in nuclear DNA. Mutat Res. 691 (1-2), 64-71 (2010).
    • (2010) Mutat Res , vol.691 , Issue.1-2 , pp. 64-71
    • Crabbe, R.A.1    Hill, K.A.2
  • 64
    • 13544276920 scopus 로고    scopus 로고
    • A carcinogenic western diet does not induce somatic mutations in various target tissues of transgenic C56BL/6 mice
    • Hernandez, L. G., & Heddle, J. A. A carcinogenic western diet does not induce somatic mutations in various target tissues of transgenic C56BL/6 mice. Mutat Res. 570 (2), 185-196 (2005).
    • (2005) Mutat Res , vol.570 , Issue.2 , pp. 185-196
    • Hernandez, L.G.1    Heddle, J.A.2
  • 65
    • 85016246439 scopus 로고    scopus 로고
    • Dose and temporal evaluation of ethylene oxide-induced mutagenicity in the lungs of male big blue mice following inhalation exposure to carcinogenic concentrations
    • Manjanatha, M. G. et al. Dose and temporal evaluation of ethylene oxide-induced mutagenicity in the lungs of male big blue mice following inhalation exposure to carcinogenic concentrations. Environ Mol Mutagen. 58 (3), 122-134 (2017).
    • (2017) Environ Mol Mutagen , vol.58 , Issue.3 , pp. 122-134
    • Manjanatha, M.G.1
  • 66
    • 72149106456 scopus 로고    scopus 로고
    • Evaluation of mutagenic mode of action in Big Blue mice fed methylphenidate for 24 weeks
    • Manjanatha, M. G. et al. Evaluation of mutagenic mode of action in Big Blue mice fed methylphenidate for 24 weeks. Mutat Res. 680 (1-2), 43-48 (2009).
    • (2009) Mutat Res , vol.680 , Issue.1-2 , pp. 43-48
    • Manjanatha, M.G.1
  • 67
    • 84862014432 scopus 로고    scopus 로고
    • Mutagenicity and DNA adduct formation by aristolochic acid in the spleen of Big Blue(R) rats
    • McDaniel, L. P. et al. Mutagenicity and DNA adduct formation by aristolochic acid in the spleen of Big Blue(R) rats. Environ Mol Mutagen. 53 (5), 358-368 (2012).
    • (2012) Environ Mol Mutagen , vol.53 , Issue.5 , pp. 358-368
    • McDaniel, L.P.1
  • 68
    • 15544373423 scopus 로고    scopus 로고
    • Age-dependent sensitivity of Big Blue transgenic mice to the mutagenicity of N-ethyl-N-nitrosourea (ENU) in liver
    • Mei, N., Heflich, R. H., Moore, M. M., & Chen, T. Age-dependent sensitivity of Big Blue transgenic mice to the mutagenicity of N-ethyl-N-nitrosourea (ENU) in liver. Mutat Res. 572 (1-2), 14-26 (2005).
    • (2005) Mutat Res , vol.572 , Issue.1-2 , pp. 14-26
    • Mei, N.1    Heflich, R.H.2    Moore, M.M.3    Chen, T.4
  • 69
    • 77954055901 scopus 로고    scopus 로고
    • The genotoxicity of acrylamide and glycidamide in big blue rats
    • Mei, N. et al. The genotoxicity of acrylamide and glycidamide in big blue rats. Toxicol Sci. 115 (2), 412-421 (2010).
    • (2010) Toxicol Sci , vol.115 , Issue.2 , pp. 412-421
    • Mei, N.1
  • 70
    • 84862808452 scopus 로고    scopus 로고
    • Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts
    • Nay, S. L., Lee, D. H., Bates, S. E., & O'Connor, T. R. Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts. DNA Repair (Amst). 11 (5), 502-510 (2012).
    • (2012) DNA Repair (Amst) , vol.11 , Issue.5 , pp. 502-510
    • Nay, S.L.1    Lee, D.H.2    Bates, S.E.3    O'connor, T.R.4
  • 71
    • 0035885262 scopus 로고    scopus 로고
    • Comparison of the mutant frequencies and mutation spectra of three non-genotoxic carcinogens, oxazepam, phenobarbital, and Wyeth 14,643, at the lambdacII locus in Big Blue transgenic mice
    • Singh, V. K., Ganesh, L., Cunningham, M. L., & Shane, B. S. Comparison of the mutant frequencies and mutation spectra of three non-genotoxic carcinogens, oxazepam, phenobarbital, and Wyeth 14,643, at the lambdacII locus in Big Blue transgenic mice. Biochem Pharmacol. 62 (6), 685-692 (2001).
    • (2001) Biochem Pharmacol , vol.62 , Issue.6 , pp. 685-692
    • Singh, V.K.1    Ganesh, L.2    Cunningham, M.L.3    Shane, B.S.4
  • 72
    • 0034691685 scopus 로고    scopus 로고
    • Interpretation of mutational spectra from different genes: Analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue rats
    • Stuart, G. R. et al. Interpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue rats. Mutat Res. 452 (1), 101-121 (2000).
    • (2000) Mutat Res , vol.452 , Issue.1 , pp. 101-121
    • Stuart, G.R.1
  • 73
    • 84902506446 scopus 로고    scopus 로고
    • Mutagenicity of furan in female Big Blue B6C3F1 mice
    • Terrell, A. N. et al. Mutagenicity of furan in female Big Blue B6C3F1 mice. Mutat Res Genet Toxicol Environ Mutagen. 770 46-54 (2014).
    • (2014) Mutat Res Genet Toxicol Environ Mutagen , vol.770 , pp. 46-54
    • Terrell, A.N.1
  • 74
    • 84938739537 scopus 로고    scopus 로고
    • Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue(R) transgenic F344 rats
    • Thompson, C. M. et al. Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue(R) transgenic F344 rats. Environ Mol Mutagen. 56 (7), 621-628 (2015).
    • (2015) Environ Mol Mutagen , vol.56 , Issue.7 , pp. 621-628
    • Thompson, C.M.1
  • 75
    • 8444225729 scopus 로고    scopus 로고
    • Time course of cII gene mutant manifestation in the liver, spleen, and bone marrow of N-ethyl-N-nitrosourea-treated Big Blue transgenic mice
    • Wang, J., Liu, X., Heflich, R. H., & Chen, T. Time course of cII gene mutant manifestation in the liver, spleen, and bone marrow of N-ethyl-N-nitrosourea-treated Big Blue transgenic mice. Toxicol Sci. 82 (1), 124-128 (2004).
    • (2004) Toxicol Sci , vol.82 , Issue.1 , pp. 124-128
    • Wang, J.1    Liu, X.2    Heflich, R.H.3    Chen, T.4
  • 76
    • 0030936458 scopus 로고    scopus 로고
    • Chronic toxicity of environmental contaminants: Sentinels and biomarkers
    • LeBlanc, G. A., & Bain, L. J. Chronic toxicity of environmental contaminants: sentinels and biomarkers. Environ Health Perspect. 105 Suppl 1 65-80 (1997).
    • (1997) Environ Health Perspect , vol.105 , pp. 65-80
    • Leblanc, G.A.1    Bain, L.J.2
  • 77
    • 36148933380 scopus 로고    scopus 로고
    • Aristolochic acid mutagenesis: Molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer
    • Arlt, V. M. et al. Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer. Carcinogenesis. 28 (11), 2253-2261 (2007).
    • (2007) Carcinogenesis , vol.28 , Issue.11 , pp. 2253-2261
    • Arlt, V.M.1
  • 78
    • 45849117920 scopus 로고    scopus 로고
    • Second-hand smoke and human lung cancer
    • Besaratinia, A., & Pfeifer, G. P. Second-hand smoke and human lung cancer. Lancet Oncol. 9 (7), 657-666 (2008).
    • (2008) Lancet Oncol , vol.9 , Issue.7 , pp. 657-666
    • Besaratinia, A.1    Pfeifer, G.P.2


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