메뉴 건너뛰기




Volumn 39, Issue 2-3, 2002, Pages 245-253

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mutagenesis in cultured Big Blue™ rat mammary epithelial and fibroblast cells

Author keywords

2 amino 1 methyl 6 phenylimidazo 4,5 b pyridine (PhIP); Big Blue rat; Mammary epithelial cells; Mutagenesis; S9

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; ALKYLATING AGENT; ETHYLNITROSOUREA; GLUTATHIONE; GLUTATHIONE TRANSFERASE;

EID: 0036207610     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.10059     Document Type: Conference Paper
Times cited : (15)

References (59)
  • 3
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 0034637708 scopus 로고    scopus 로고
    • Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide
    • (2000) Cancer Lett , vol.156 , pp. 167-175
    • Coles, B.1    Yang, M.2    Lang, N.P.3    Kadlubar, F.F.4
  • 11
    • 0031752257 scopus 로고    scopus 로고
    • Bioactivation of the proximal food mutagen 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) to DNA-binding species by human mammary gland enzymes
    • (1998) Nutrition , vol.14 , pp. 683-686
    • Dubuisson, J.G.1    Gaubatz, J.W.2
  • 12
    • 0034695032 scopus 로고    scopus 로고
    • Micronuclei and gene mutations in transgenic Big Blue® mouse and rat fibroblasts after exposure to the epoxide metabolites of 1,3-butadiene
    • (2000) Mutat Res , vol.472 , pp. 105-117
    • Erexson, G.L.1    Tindall, K.R.2
  • 15
    • 0028949033 scopus 로고
    • Cytotoxicity, DNA adduct formation and DNA repair induced by 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline and 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in cultured human mammary epithelial cells
    • (1995) Carcinogenesis , vol.16 , pp. 775-779
    • Fan, L.1    Schut, H.A.2    Snyderwine, E.G.3
  • 18
    • 0033060682 scopus 로고    scopus 로고
    • Cytotoxic and mutagenic response of mismatch repair-defective human cancer cells exposed to a food-associated heterocyclic amine
    • (1999) Carcinogenesis , vol.20 , pp. 391-394
    • Glaab, W.E.1    Skopek, T.R.2
  • 19
    • 0019167355 scopus 로고
    • Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
    • (1980) Anal Biochem , vol.106 , pp. 207-212
    • Griffith, O.W.1
  • 23
    • 0032940205 scopus 로고    scopus 로고
    • Mutant manifestation: The time factor in somatic mutagenesis
    • (1999) Mutagenesis , vol.14 , pp. 1-3
    • Heddle, J.A.1
  • 29
    • 0030971431 scopus 로고    scopus 로고
    • Mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) when activated by hamster pancreatic duct epithelial cells: A chemopreventive role for glutathione
    • (1997) Mutat Res , vol.375 , pp. 73-78
    • Lawson, T.1    Kolar, C.2    Reyes, T.3
  • 33
    • 0028095423 scopus 로고
    • Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: A possible mechanism of organ specificity in their carcinogenesis
    • (1994) Cancer Res , vol.54 , pp. 4920-4926
    • Lin, D.1    Meyer, D.J.2    Ketterer, B.3    Lang, N.P.4    Kadlubar, F.F.5
  • 38
  • 39
    • 0031818531 scopus 로고    scopus 로고
    • The cellular stress response induced by aqueous extracts of cigarette smoke is critically dependent on the intracellular glutathione concentration
    • (1998) Carcinogenesis , vol.19 , pp. 797-801
    • Muller, T.1    Gebel, S.2
  • 43
    • 0017613512 scopus 로고
    • A simplification of the protein assay method of Lowry et al. Which is more generally applicable
    • (1977) Anal Biochem , vol.83 , pp. 346-356
    • Peterson, G.L.1
  • 51
    • 0032806272 scopus 로고    scopus 로고
    • Mammary gland carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats: Possible mechanisms
    • (1999) Cancer Lett , vol.143 , pp. 211-215
    • Snyderwine, E.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.