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Volumn 21, Issue 5, 2018, Pages 439-448

A review of the effects of Capsicum annuum L. And its constituent, capsaicin, in metabolic syndrome

Author keywords

Capsicum annuum; Cardiovascular disease; Diabetes; Dyslipidemia; Hypertension; Metabolic syndrome; Obesity; Red pepper

Indexed keywords

ADIPOCYTOKINE; ALPHA GLUCOSIDASE; AMYLASE; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; GLUCAGON LIKE PEPTIDE 1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRIACYLGLYCEROL; VANILLOID RECEPTOR 1; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 85045311886     PISSN: 20083866     EISSN: 20083874     Source Type: Journal    
DOI: 10.22038/IJBMS.2018.25200.6238     Document Type: Review
Times cited : (130)

References (88)
  • 1
    • 85045310722 scopus 로고    scopus 로고
    • A Review on metabolic syndrome
    • Marjani A. A Review on metabolic syndrome. J Endocrinol Metab 2012; 2:166-170.
    • (2012) J Endocrinol Metab , vol.2 , pp. 166-170
    • Marjani, A.1
  • 2
    • 84856957565 scopus 로고    scopus 로고
    • Anti-inflammatory properties of culinary herbs and spices that ameliorate the effects of metabolic syndrome
    • Jungbauer A, Medjakovic S. Anti-inflammatory properties of culinary herbs and spices that ameliorate the effects of metabolic syndrome. Maturitas 2012; 71:227-239.
    • (2012) Maturitas , vol.71 , pp. 227-239
    • Jungbauer, A.1    Medjakovic, S.2
  • 3
    • 84962644046 scopus 로고    scopus 로고
    • Grapes (Vitis vinifera) as a Potential Candidate for the Therapy of the Metabolic Syndrome
    • Akaberi M, Hosseinzadeh H. Grapes (Vitis vinifera) as a Potential Candidate for the Therapy of the Metabolic Syndrome. Phtother Res 2016; 30:540-556.
    • (2016) Phtother Res , vol.30 , pp. 540-556
    • Akaberi, M.1    Hosseinzadeh, H.2
  • 4
    • 84922404807 scopus 로고    scopus 로고
    • A review of the effects of Nigella sativa L. And its constituent, thymoquinone, in metabolic syndrome
    • Razavi B, Hosseinzadeh H. A review of the effects of Nigella sativa L. and its constituent, thymoquinone, in metabolic syndrome. J Endocrinol Invest 2014; 37:1031-1040.
    • (2014) J Endocrinol Invest , vol.37 , pp. 1031-1040
    • Razavi, B.1    Hosseinzadeh, H.2
  • 5
    • 84944062916 scopus 로고    scopus 로고
    • A review on the effects of Allium sativum (Garlic) in metabolic syndrome
    • Hosseini A, Hosseinzadeh H. A review on the effects of Allium sativum (Garlic) in metabolic syndrome. J Endocrinol Invest 2015; 38:1147-1157.
    • (2015) J Endocrinol Invest , vol.38 , pp. 1147-1157
    • Hosseini, A.1    Hosseinzadeh, H.2
  • 6
    • 84968546960 scopus 로고    scopus 로고
    • Rosemary (Rosmarinus officinalis) as a potential therapeutic plant in metabolic syndrome: A review
    • Vahdati Hassani F, Shirani K, Hosseinzadeh H. Rosemary (Rosmarinus officinalis) as a potential therapeutic plant in metabolic syndrome: a review. Naunyn-Schmiedeberg’s Arch Pharmacol 2016; 389:931-949.
    • (2016) Naunyn-Schmiedeberg’s Arch Pharmacol , vol.389 , pp. 931-949
    • Vahdati Hassani, F.1    Shirani, K.2    Hosseinzadeh, H.3
  • 7
    • 85017473366 scopus 로고    scopus 로고
    • Effects of avocado (Persea americana) on metabolic syndrome: A comprehensive systematic review
    • Tabeshpour J, Razavi BM, Hosseinzadeh H. Effects of avocado (Persea americana) on metabolic syndrome: a comprehensive systematic review. Phytother Res 2017; 31:819-837.
    • (2017) Phytother Res , vol.31 , pp. 819-837
    • Tabeshpour, J.1    Razavi, B.M.2    Hosseinzadeh, H.3
  • 8
    • 85018421343 scopus 로고    scopus 로고
    • A review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome
    • Tabeshpour J, Imenshahidi M, Hosseinzadeh H. A review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome. Iran J Basic Med Sci 2017; 20:557-568.
    • (2017) Iran J Basic Med Sci , vol.20 , pp. 557-568
    • Tabeshpour, J.1    Imenshahidi, M.2    Hosseinzadeh, H.3
  • 9
    • 85003816108 scopus 로고    scopus 로고
    • Cinnamon effects on metabolic syndrome: A review based on its mechanisms
    • Mollazadeh H, Hosseinzadeh H. Cinnamon effects on metabolic syndrome: a review based on its mechanisms. Iran J Basic Med Sci 2016; 19:1258-1270.
    • (2016) Iran J Basic Med Sci , vol.19 , pp. 1258-1270
    • Mollazadeh, H.1    Hosseinzadeh, H.2
  • 10
    • 84908698574 scopus 로고    scopus 로고
    • Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid
    • Hosseinzadeh H, Nassiri-Asl M. Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid. J Endocrinol Invest 2014; 37:783-788.
    • (2014) J Endocrinol Invest , vol.37 , pp. 783-788
    • Hosseinzadeh, H.1    Nassiri-Asl, M.2
  • 11
    • 85015149789 scopus 로고    scopus 로고
    • Saffron: A promising natural medicine in the treatment of metabolic syndrome
    • Razavi B, Hosseinzadeh H. Saffron: a promising natural medicine in the treatment of metabolic syndrome. J Sci Food Agric 2016; 97: 1679-1685.
    • (2016) J Sci Food Agric , vol.97 , pp. 1679-1685
    • Razavi, B.1    Hosseinzadeh, H.2
  • 12
    • 85021455037 scopus 로고    scopus 로고
    • Review of Garcinia mangostana and its xanthones in metabolic syndrome and related complications
    • Tousian Shandiz H, Razavi BM, Hosseinzadeh H. Review of Garcinia mangostana and its xanthones in metabolic syndrome and related complications. Phytother Res 2017; 31:1173-1182.
    • (2017) Phytother Res , vol.31 , pp. 1173-1182
    • Tousian Shandiz, H.1    Razavi, B.M.2    Hosseinzadeh, H.3
  • 13
    • 85020011922 scopus 로고    scopus 로고
    • Protective effects of green tea on olanzapine-induced-metabolic syndrome in rats
    • Razavi BM, Lookian F, Hosseinzadeh H. Protective effects of green tea on olanzapine-induced-metabolic syndrome in rats. Biomed Pharmacother 2017; 92: 726-731.
    • (2017) Biomed Pharmacother , vol.92 , pp. 726-731
    • Razavi, B.M.1    Lookian, F.2    Hosseinzadeh, H.3
  • 14
    • 65549113416 scopus 로고    scopus 로고
    • Pepper and capsaicin (Capsicum and Piper species)
    • Barceloux DG. Pepper and capsaicin (Capsicum and Piper species). Dis Mon 2009; 55:380-390.
    • (2009) Dis Mon , vol.55 , pp. 380-390
    • Barceloux, D.G.1
  • 15
    • 79951618611 scopus 로고    scopus 로고
    • Red pepper: Overview of potential health benefits
    • Singletary K. Red pepper: overview of potential health benefits. Nut Today 2011; 46:33-47.
    • (2011) Nut Today , vol.46 , pp. 33-47
    • Singletary, K.1
  • 17
    • 84969795616 scopus 로고    scopus 로고
    • Phytochemistry and gastrointestinal benefits of the medicinal spice, Capsicum annuum L.(Chilli): A review
    • Maji AK, Banerji P. Phytochemistry and gastrointestinal benefits of the medicinal spice, Capsicum annuum L.(Chilli): a review. J Complement Integr Med 2016; 13:97-122.
    • (2016) J Complement Integr Med , vol.13 , pp. 97-122
    • Maji, A.K.1    Banerji, P.2
  • 18
    • 33748428494 scopus 로고    scopus 로고
    • A reason to season: The therapeutic benefits of spices and culinary herbs
    • Low Dog T. A reason to season: the therapeutic benefits of spices and culinary herbs. Explore (NY) 2006; 2:446-449.
    • (2006) Explore (NY) , vol.2 , pp. 446-449
    • Low Dog, T.1
  • 19
    • 84893496353 scopus 로고    scopus 로고
    • Antioxidant activity of phenolics in leaves of three red pepper (Capsicum annuum) cultivars
    • Kim W-R, Kim EO, Kang K, Oidovsambuu S, Jung SH, Kim BS, et al. Antioxidant activity of phenolics in leaves of three red pepper (Capsicum annuum) cultivars. J Agric Food Chem 2014; 62:850-859.
    • (2014) J Agric Food Chem , vol.62 , pp. 850-859
    • Kim, W.-R.1    Kim, E.O.2    Kang, K.3    Oidovsambuu, S.4    Jung, S.H.5    Kim, B.S.6
  • 20
    • 84855904085 scopus 로고    scopus 로고
    • The effects of capsaicin and capsiate on energy balance: Critical review and metaanalyses of studies in humans
    • Ludy M-J, Moore GE, Mattes RD. The effects of capsaicin and capsiate on energy balance: critical review and metaanalyses of studies in humans. Chem Senses 2012; 37:103-21.
    • (2012) Chem Senses , vol.37 , pp. 103-121
    • Ludy, M.-J.1    Moore, G.E.2    Mattes, R.D.3
  • 21
    • 77952174535 scopus 로고    scopus 로고
    • Topical capsaicin. The fire of a ‘hot’medicine is reignited.
    • Papoiu AD, Yosipovitch G. Topical capsaicin. The fire of a ‘hot’medicine is reignited. Expert Opin Pharmacother 2010; 11:1359-1371.
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 1359-1371
    • Papoiu, A.D.1    Yosipovitch, G.2
  • 22
    • 56949104715 scopus 로고    scopus 로고
    • Capsaicin: A review of its pharmacology and clinical applications
    • Hayman M, Kam PC. Capsaicin: a review of its pharmacology and clinical applications. Curr Anaesth Crit Care 2008; 19:338-343.
    • (2008) Curr Anaesth Crit Care , vol.19 , pp. 338-343
    • Hayman, M.1    Kam, P.C.2
  • 23
    • 7444222903 scopus 로고    scopus 로고
    • Spices as influencers of body metabolism: An overview of three decades of research
    • Srinivasan K. Spices as influencers of body metabolism: an overview of three decades of research. Food Res Int 2005; 38:77-86.
    • (2005) Food Res Int , vol.38 , pp. 77-86
    • Srinivasan, K.1
  • 24
    • 79953004193 scopus 로고    scopus 로고
    • Chemical composition of the pepper fruit extracts of hot cultivars Capsicum annuum L
    • Wesolowska A, Jadczak D, Grzeszczuk M. Chemical composition of the pepper fruit extracts of hot cultivars Capsicum annuum L. Acta Sci Pol Hortorum Cultus 2011; 10:171-184.
    • (2011) Acta Sci Pol Hortorum Cultus , vol.10 , pp. 171-184
    • Wesolowska, A.1    Jadczak, D.2    Grzeszczuk, M.3
  • 26
    • 1942467891 scopus 로고    scopus 로고
    • Systematic review of topical capsaicin for the treatment of chronic pain
    • Mason L, Moore RA, Derry S, Edwards JE, McQuay HJ. Systematic review of topical capsaicin for the treatment of chronic pain. BMJ 2004; 328:991.
    • (2004) BMJ , vol.328 , pp. 991
    • Mason, L.1    Moore, R.A.2    Derry, S.3    Edwards, J.E.4    McQuay, H.J.5
  • 27
    • 79953024415 scopus 로고    scopus 로고
    • PPARalpha activation by culinary herbs and spices
    • Mueller M, Beck V, Jungbauer A. PPARalpha activation by culinary herbs and spices. Planta Med 2011; 77:497-504.
    • (2011) Planta Med , vol.77 , pp. 497-504
    • Mueller, M.1    Beck, V.2    Jungbauer, A.3
  • 28
    • 0023145243 scopus 로고
    • Effect of pure capsaicinoids (Capsaicin and dihydrocapsaicin) on plasma lipids and lipoprotein concentrations of turmey poults
    • Negulesco J A, Noel S A, Newman, H A I. Effect of pure capsaicinoids (capsaicin and dihydrocapsaicin) on plasma lipids and lipoprotein concentrations of turmey poults. Atherosclerosis 1987; 64:85-90.
    • (1987) Atherosclerosis , vol.64 , pp. 85-90
    • Negulesco, J.A.1    Noel, S.A.2    Newman, H.A.I.3
  • 29
    • 33744982431 scopus 로고    scopus 로고
    • Beneficial influence of dietary curcumin, capsaicin and garlic on erythrocyte integrity in high-fat fed rats
    • Kempaiah RK, Srinivasan K. Beneficial influence of dietary curcumin, capsaicin and garlic on erythrocyte integrity in high-fat fed rats. J Nutr Biochem 2006; 17:471-478.
    • (2006) J Nutr Biochem , vol.17 , pp. 471-478
    • Kempaiah, R.K.1    Srinivasan, K.2
  • 30
    • 84865412583 scopus 로고    scopus 로고
    • Potentiation of hypolipidemic and weight-reducing influence of dietary tender cluster bean (Cyamopsis tetragonoloba) when combined with capsaicin in high-fat-fed rats
    • Pande S, Srinivasan K. Potentiation of hypolipidemic and weight-reducing influence of dietary tender cluster bean (Cyamopsis tetragonoloba) when combined with capsaicin in high-fat-fed rats. J Agric Food Chem 2012; 60:8155-8162.
    • (2012) J Agric Food Chem , vol.60 , pp. 8155-8162
    • Pande, S.1    Srinivasan, K.2
  • 31
    • 84902281006 scopus 로고    scopus 로고
    • Hypolipidemic effect of aqueous extracts of selected spices and their mixture on diet-induced hypercholesterolemia in Wistar rats
    • Otunola G, Oloyede O, Oladiji A, Afolayan A. Hypolipidemic effect of aqueous extracts of selected spices and their mixture on diet-induced hypercholesterolemia in Wistar rats. Can J Pure Appl Sci 2012; 6:2063-2071.
    • (2012) Can J Pure Appl Sci , vol.6 , pp. 2063-2071
    • Otunola, G.1    Oloyede, O.2    Oladiji, A.3    Afolayan, A.4
  • 32
    • 0038324407 scopus 로고    scopus 로고
    • Red pepper attenuates cholesteryl ester transfer protein activity and atherosclerosis in cholesterol-fed rabbits
    • Kwon MJ, Song YS, Choi MS, Song YO. Red pepper attenuates cholesteryl ester transfer protein activity and atherosclerosis in cholesterol-fed rabbits. Clin Chim Acta 2003; 332:37-44.
    • (2003) Clin Chim Acta , vol.332 , pp. 37-44
    • Kwon, M.J.1    Song, Y.S.2    Choi, M.S.3    Song, Y.O.4
  • 33
    • 37349100145 scopus 로고    scopus 로고
    • Hypolipidemic and antioxidant effects of dietary curcumin and capsaicin in induced hypercholesterolemic rats
    • Manjunatha H, Srinivasan K. Hypolipidemic and antioxidant effects of dietary curcumin and capsaicin in induced hypercholesterolemic rats. Lipids 2007; 42:1133-1142.
    • (2007) Lipids , vol.42 , pp. 1133-1142
    • Manjunatha, H.1    Srinivasan, K.2
  • 34
    • 77955960077 scopus 로고    scopus 로고
    • Hypoxanthine levels in human urine serve as a screening indicator for the plasma total cholesterol and low-density lipoprotein modulation activities of fermented red pepper paste
    • Kim Y, Park Y-J, Yang S-O, Kim S-H, Hyun S-H, Cho S, et al. Hypoxanthine levels in human urine serve as a screening indicator for the plasma total cholesterol and low-density lipoprotein modulation activities of fermented red pepper paste. Nut Res 2010; 30:455-461.
    • (2010) Nut Res , vol.30 , pp. 455-461
    • Kim, Y.1    Park, Y.-J.2    Yang, S.-O.3    Kim, S.-H.4    Hyun, S.-H.5    Cho, S.6
  • 35
    • 84928206720 scopus 로고    scopus 로고
    • Supplementation with Aspergillus oryzae-fermented kochujang lowers serum cholesterol in subjects with hyperlipidemia
    • Lim J-H, Jung E-S, Choi E-K, Jeong D-Y, Jo S-W, Jin J-H, et al. Supplementation with Aspergillus oryzae-fermented kochujang lowers serum cholesterol in subjects with hyperlipidemia. Clin Nut 2015; 34:383-387.
    • (2015) Clin Nut , vol.34 , pp. 383-387
    • Lim, J.-H.1    Jung, E.-S.2    Choi, E.-K.3    Jeong, D.-Y.4    Jo, S.-W.5    Jin, J.-H.6
  • 38
    • 80051781968 scopus 로고    scopus 로고
    • Comparative study on the chemical composition, antioxidant properties and hypoglycaemic activities of two Capsicum annuum L. Cultivars (Acuminatum small and Cerasiferum)
    • Tundis R, Loizzo MR, Menichini F, Bonesi M, Conforti F, Statti G, et al. Comparative study on the chemical composition, antioxidant properties and hypoglycaemic activities of two Capsicum annuum L. cultivars (Acuminatum small and Cerasiferum). Plant Foods Hum Nutr 2011; 66:261-269.
    • (2011) Plant Foods Hum Nutr , vol.66 , pp. 261-269
    • Tundis, R.1    Loizzo, M.R.2    Menichini, F.3    Bonesi, M.4    Conforti, F.5    Statti, G.6
  • 40
    • 85012822925 scopus 로고    scopus 로고
    • Dietary Capsaicin Protects Cardiometabolic Organs from Dysfunction
    • Sun F, Xiong S, Zhu Z. Dietary Capsaicin Protects Cardiometabolic Organs from Dysfunction. Nutrients 2016; 8.
    • (2016) Nutrients , pp. 8
    • Sun, F.1    Xiong, S.2    Zhu, Z.3
  • 41
    • 84938825893 scopus 로고    scopus 로고
    • Hypoglycemic and Hypocholesterolemia Effects of Intragastric Administration of Dried Red Chili Pepper (Capsicum Annum) in Alloxan-Induced Diabetic Male Albino Rats Fed with High-Fat-Diet
    • Magied MMA, Salama NAR, Ali MR. Hypoglycemic and Hypocholesterolemia Effects of Intragastric Administration of Dried Red Chili Pepper (Capsicum Annum) in Alloxan-Induced Diabetic Male Albino Rats Fed with High-Fat-Diet. J Food Nut Res 2014; 2:850-856.
    • (2014) J Food Nut Res , vol.2 , pp. 850-856
    • Magied, M.1    Salama, N.2    Ali, M.R.3
  • 42
    • 19944427805 scopus 로고    scopus 로고
    • Anti-hyperlycemic and hypolipidemic effect of oral administration of Capsicum frutescens in male STZ-diabetic rats
    • Roghani M, Baluchnejadmojarad T, Sohrabi Z, Sadeghi M. Anti-hyperlycemic and hypolipidemic effect of oral administration of Capsicum frutescens in male STZ-diabetic rats. J Med Plants 2004; 2:47-52.
    • (2004) J Med Plants , vol.2 , pp. 47-52
    • Roghani, M.1    Baluchnejadmojarad, T.2    Sohrabi, Z.3    Sadeghi, M.4
  • 43
    • 84901781370 scopus 로고    scopus 로고
    • In Vitro Inhibitory Potential Against Key Enzymes Relevant for Hyperglycemia and Hypertension of Red Pepper (Capsicum annuum L.) Including Pericarp, Placenta, and Stalk
    • Chen L, Kang Y-H. In Vitro Inhibitory Potential Against Key Enzymes Relevant for Hyperglycemia and Hypertension of Red Pepper (Capsicum annuum L.) Including Pericarp, Placenta, and Stalk. J Food Biochem 2014; 38:300-306.
    • (2014) J Food Biochem , vol.38 , pp. 300-306
    • Chen, L.1    Kang, Y.-H.2
  • 44
    • 33747387241 scopus 로고    scopus 로고
    • Effects of chili consumption on postprandial glucose, insulin, and energy metabolism
    • Ahuja KD, Robertson IK, Geraghty DP, Ball MJ. Effects of chili consumption on postprandial glucose, insulin, and energy metabolism. Am J Clin Nutr 2006; 84:63-69.
    • (2006) Am J Clin Nutr , vol.84 , pp. 63-69
    • Ahuja, K.D.1    Robertson, I.K.2    Geraghty, D.P.3    Ball, M.J.4
  • 45
    • 84960487758 scopus 로고    scopus 로고
    • Capsaicin-containing chili improved postprandial hyperglycemia, hyperinsulinemia, and fasting lipid disorders in women with gestational diabetes mellitus and lowered the incidence of large-for-gestational-age newborns
    • Yuan LJ, Qin Y, Wang L, Zeng Y, Chang H, Wang J, et al. Capsaicin-containing chili improved postprandial hyperglycemia, hyperinsulinemia, and fasting lipid disorders in women with gestational diabetes mellitus and lowered the incidence of large-for-gestational-age newborns. Clin Nutr 2016; 35:388-393.
    • (2016) Clin Nutr , vol.35 , pp. 388-393
    • Yuan, L.J.1    Qin, Y.2    Wang, L.3    Zeng, Y.4    Chang, H.5    Wang, J.6
  • 46
    • 23844457669 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide and hypertension
    • Deng PY, Li YJ. Calcitonin gene-related peptide and hypertension. Peptides 2005; 26:1676-1685.
    • (2005) Peptides , vol.26 , pp. 1676-1685
    • Deng, P.Y.1    Li, Y.J.2
  • 48
    • 84995677489 scopus 로고    scopus 로고
    • Phytochemistry and mode of action of some tropical spices in the management of type-2 diabetes and hypertension
    • Adefegha SA, Oboh G. Phytochemistry and mode of action of some tropical spices in the management of type-2 diabetes and hypertension. African J Pharm Pharmacol 2013; 7:332-46.
    • (2013) African J Pharm Pharmacol , vol.7 , pp. 332-346
    • Adefegha, S.A.1    Oboh, G.2
  • 49
    • 79957644116 scopus 로고    scopus 로고
    • Antiobesity activity of methanol extract from hot pepper (Capsicum annuum L.) seeds in 3T3-L1 adipocyte
    • Jeon G, Choi Y, Lee S-M, Kim Y, Jeong H-S, Lee J. Antiobesity activity of methanol extract from hot pepper (Capsicum annuum L.) seeds in 3T3-L1 adipocyte. Food Sci Biotechnol 2010; 19:1123-1127.
    • (2010) Food Sci Biotechnol , vol.19 , pp. 1123-1127
    • Jeon, G.1    Choi, Y.2    Lee, S.-M.3    Kim, Y.4    Jeong, H.-S.5    Lee, J.6
  • 50
    • 0019488859 scopus 로고
    • Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: Effects on nociceptive behavior and cardiovascular regulation
    • Virus RM, Knuepfer MM, McManus DQ, Brody MJ, Gebhart GF. Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on nociceptive behavior and cardiovascular regulation. Eur J Pharmacol 1981; 72:209-217.
    • (1981) Eur J Pharmacol , vol.72 , pp. 209-217
    • Virus, R.M.1    Knuepfer, M.M.2    McManus, D.Q.3    Brody, M.J.4    Gebhart, G.F.5
  • 51
    • 0024377651 scopus 로고
    • Capsaicin-sensitive primary afferents are involved in the hypotensive effect of neurotensin in ganglion-blocked guinea pigs
    • Rioux F, Lemieux M, Roy G. Capsaicin-sensitive primary afferents are involved in the hypotensive effect of neurotensin in ganglion-blocked guinea pigs. Peptides 1989; 10:1033-40.
    • (1989) Peptides , vol.10 , pp. 1033-1040
    • Rioux, F.1    Lemieux, M.2    Roy, G.3
  • 52
    • 0027339994 scopus 로고
    • The effects of neonatal capsaicin on plasma levels and tissue contents of CGRP
    • Wimalawansa SJ. The effects of neonatal capsaicin on plasma levels and tissue contents of CGRP. Peptides 1993; 14:247-252.
    • (1993) Peptides , vol.14 , pp. 247-252
    • Wimalawansa, S.J.1
  • 53
    • 0023567093 scopus 로고
    • Cardiovascular effects of substance P and capsaicin microinjected into the nucleus tractus solitarii of the rat
    • Lukovic L, de Jong W, de Wied D. Cardiovascular effects of substance P and capsaicin microinjected into the nucleus tractus solitarii of the rat. Brain Res 1987; 422:312-318.
    • (1987) Brain Res , vol.422 , pp. 312-318
    • Lukovic, L.1    de Jong, W.2    de Wied, D.3
  • 55
    • 0037119242 scopus 로고    scopus 로고
    • Prenatal malnutritioninduced hypertension in young rats is prevented by neonatal capsaicin treatment
    • Perez H, Ruiz S, Soto-Moyano R. Prenatal malnutritioninduced hypertension in young rats is prevented by neonatal capsaicin treatment. Neurosci Lett 2002; 328:253-256.
    • (2002) Neurosci Lett , vol.328 , pp. 253-256
    • Perez, H.1    Ruiz, S.2    Soto-Moyano, R.3
  • 56
    • 0028134754 scopus 로고
    • Vasodilatation induced by capsaicin in rat mesenteric vessels is probably independent of nitric oxide synthesis
    • Potenza MA, De Salvatore G, Montagnani M, Serio M, Mitolo-Chieppa D. Vasodilatation induced by capsaicin in rat mesenteric vessels is probably independent of nitric oxide synthesis. Pharmacol Res 1994; 30:253-261.
    • (1994) Pharmacol Res , vol.30 , pp. 253-261
    • Potenza, M.A.1    De Salvatore, G.2    Montagnani, M.3    Serio, M.4    Mitolo-Chieppa, D.5
  • 57
    • 78049443064 scopus 로고    scopus 로고
    • Activation of TRPV1 by dietary capsaicin improves endotheliumdependent vasorelaxation and prevents hypertension
    • Yang D, Luo Z, Ma S, Wong WT, Ma L, Zhong J, et al. Activation of TRPV1 by dietary capsaicin improves endotheliumdependent vasorelaxation and prevents hypertension. Cell Metab 2010; 12:130-141.
    • (2010) Cell Metab , vol.12 , pp. 130-141
    • Yang, D.1    Luo, Z.2    Ma, S.3    Wong, W.T.4    Ma, L.5    Zhong, J.6
  • 58
    • 80255138041 scopus 로고    scopus 로고
    • A new way to lower blood pressure: Pass the chili peppers please!
    • Sessa WC. A new way to lower blood pressure: pass the chili peppers please! Cell Metab 2010; 12:109-110.
    • (2010) Cell Metab , vol.12 , pp. 109-110
    • Sessa, W.C.1
  • 59
    • 84925684948 scopus 로고    scopus 로고
    • Dietary capsaicin ameliorates pressure overload-induced cardiac hypertrophy and fibrosis through the transient receptor potential vanilloid type1
    • Wang Q, Ma S, Li D, Zhang Y, Tang B, Qiu C, et al. Dietary capsaicin ameliorates pressure overload-induced cardiac hypertrophy and fibrosis through the transient receptor potential vanilloid type1. Am J Hypertens 2014; 27:1521-1529.
    • (2014) Am J Hypertens , vol.27 , pp. 1521-1529
    • Wang, Q.1    Ma, S.2    Li, D.3    Zhang, Y.4    Tang, B.5    Qiu, C.6
  • 60
    • 34250177320 scopus 로고    scopus 로고
    • Evaluation of pepper (Capsicum annum) for management of diabetes and hypertension
    • Kwon Y-I, Apostolidis E, Shetty K. Evaluation of pepper (Capsicum annum) for management of diabetes and hypertension. J Food Biochem 2007; 31:370-385.
    • (2007) J Food Biochem , vol.31 , pp. 370-385
    • Kwon, Y.-I.1    Apostolidis, E.2    Shetty, K.3
  • 62
    • 64549085580 scopus 로고    scopus 로고
    • Capsaicin, arterial hypertensive crisis and acute myocardial infarction associated with high levels of thyroid stimulating hormone
    • Patane S, Marte F, Di Bella G, Cerrito M, Coglitore S. Capsaicin, arterial hypertensive crisis and acute myocardial infarction associated with high levels of thyroid stimulating hormone. Int J Cardiol 2009; 134:130-132.
    • (2009) Int J Cardiol , vol.134 , pp. 130-132
    • Patane, S.1    Marte, F.2    Di Bella, G.3    Cerrito, M.4    Coglitore, S.5
  • 63
    • 78650034467 scopus 로고    scopus 로고
    • Mechanisms underlying the hypertensive response induced by capsaicin
    • Dutta A, Deshpande SB. Mechanisms underlying the hypertensive response induced by capsaicin. Int J Cardiol 2010; 145:358-359.
    • (2010) Int J Cardiol , vol.145 , pp. 358-359
    • Dutta, A.1    Deshpande, S.B.2
  • 64
    • 84876875657 scopus 로고    scopus 로고
    • Inhibitory effects of Capsicum annuum L. Water extracts on lipoprotein lipase activity in 3T3-L1 cells
    • Baek J, Lee J, Kim K, Kim T, Kim D, Kim C, et al. Inhibitory effects of Capsicum annuum L. water extracts on lipoprotein lipase activity in 3T3-L1 cells. Nutr Res Pract 2013; 7:96-102.
    • (2013) Nutr Res Pract , vol.7 , pp. 96-102
    • Baek, J.1    Lee, J.2    Kim, K.3    Kim, T.4    Kim, D.5    Kim, C.6
  • 66
    • 33846565847 scopus 로고    scopus 로고
    • Active spice-derived components can inhibit inflammatory responses of adipose tissue in obesity by suppressing inflammatory actions of macrophages and release of monocyte chemoattractant protein-1 from adipocytes
    • Woo H-M, Kang J-H, Kawada T, Yoo H, Sung M-K, Yu R. Active spice-derived components can inhibit inflammatory responses of adipose tissue in obesity by suppressing inflammatory actions of macrophages and release of monocyte chemoattractant protein-1 from adipocytes. Life Sci 2007; 80:926-931.
    • (2007) Life Sci , vol.80 , pp. 926-931
    • Woo, H.-M.1    Kang, J.-H.2    Kawada, T.3    Yoo, H.4    Sung, M.-K.5    Yu, R.6
  • 67
    • 67349166934 scopus 로고    scopus 로고
    • Effects of capsaicin, green tea and CH-19 sweet pepper on appetite and energy intake in humans in negative and positive energy balance
    • Reinbach HC, Smeets A, Martinussen T, Møller P, Westerterp-Plantenga M. Effects of capsaicin, green tea and CH-19 sweet pepper on appetite and energy intake in humans in negative and positive energy balance. Clin Nut 2009; 28:260-265.
    • (2009) Clin Nut , vol.28 , pp. 260-265
    • Reinbach, H.C.1    Smeets, A.2    Martinussen, T.3    Møller, P.4    Westerterp-Plantenga, M.5
  • 68
    • 44149123364 scopus 로고    scopus 로고
    • Effects of amide constituents from pepper on adipogenesis in 3T3-L1 cells
    • Zhang H, Matsuda H, Nakamura S, Yoshikawa M. Effects of amide constituents from pepper on adipogenesis in 3T3-L1 cells. Bioorg Med Chem Lett 2008; 18:3272-3277.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 3272-3277
    • Zhang, H.1    Matsuda, H.2    Nakamura, S.3    Yoshikawa, M.4
  • 69
    • 84976512061 scopus 로고    scopus 로고
    • Hypolipidemic and Antioxidant Properties of Hot Pepper Flower (Capsicum annuum L.)
    • Marrelli M, Menichini F, Conforti F. Hypolipidemic and Antioxidant Properties of Hot Pepper Flower (Capsicum annuum L.). Plant Foods Hum Nutr 2016; 71:301-306.
    • (2016) Plant Foods Hum Nutr , vol.71 , pp. 301-306
    • Marrelli, M.1    Menichini, F.2    Conforti, F.3
  • 70
    • 43149094148 scopus 로고    scopus 로고
    • Increased lipolytic activity by high-pungency red pepper extract (Var. chungyang) in rat adipocytes in vitro
    • Do MS, Hong SE, Ha JH, Choi SM, Ahn IS, yoon JY, et al. Increased lipolytic activity by high-pungency red pepper extract (var. chungyang) in rat adipocytes in vitro. J Food Sci Nutr 2004; 9:34-38.
    • (2004) J Food Sci Nutr , vol.9 , pp. 34-38
    • Do, M.S.1    Hong, S.E.2    Ha, J.H.3    Choi, S.M.4    Ahn, I.S.5    Yoon, J.Y.6
  • 71
    • 27744455616 scopus 로고    scopus 로고
    • Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase
    • Hwang J-T, Park I-J, Shin J-I, Lee YK, Lee SK, Baik HW, et al. Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase. Biochem Biophys Res Commun 2005; 338:694-699.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 694-699
    • Hwang, J.-T.1    Park, I.-J.2    Shin, J.-I.3    Lee, Y.K.4    Lee, S.K.5    Baik, H.W.6
  • 72
    • 34548399748 scopus 로고    scopus 로고
    • Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese‐mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages
    • Kang J-H, Kim C-S, Han I-S, Kawada T, Yu R. Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese‐mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages. Febs Lett 2007; 581:4389-4396.
    • (2007) Febs Lett , vol.581 , pp. 4389-4396
    • Kang, J.-H.1    Kim, C.-S.2    Han, I.-S.3    Kawada, T.4    Yu, R.5
  • 73
    • 45449110183 scopus 로고    scopus 로고
    • Capsaicin-sensitive intestinal mucosal afferent mechanism and body fat distribution
    • Leung FW. Capsaicin-sensitive intestinal mucosal afferent mechanism and body fat distribution. Life Sci 2008; 83:1-5.
    • (2008) Life Sci , vol.83 , pp. 1-5
    • Leung, F.W.1
  • 75
    • 84894806489 scopus 로고    scopus 로고
    • Antiobese Effects of Capsaicin-Chitosan Microsphere (CCMS) in Obese Rats Induced by High Fat Diet
    • Tan S, Gao B, Tao Y, Guo J, Su Z-q. Antiobese Effects of Capsaicin-Chitosan Microsphere (CCMS) in Obese Rats Induced by High Fat Diet. J Agr Food Chem 2014; 62:1866-74.
    • (2014) J Agr Food Chem , vol.62 , pp. 1866-1874
    • Tan, S.1    Gao, B.2    Tao, Y.3    Guo, J.4    Su, Z.-Q.5
  • 76
  • 77
    • 84876294971 scopus 로고    scopus 로고
    • Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high‐fat diet‐induced obese mice
    • Lee GR, Shin MK, Yoon DJ, Kim AR, Yu R, Park NH, et al. Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high‐fat diet‐induced obese mice. Obesity 2013; 21:115-122.
    • (2013) Obesity , vol.21 , pp. 115-122
    • Lee, G.R.1    Shin, M.K.2    Yoon, D.J.3    Kim, A.R.4    Yu, R.5    Park, N.H.6
  • 78
    • 84953455691 scopus 로고    scopus 로고
    • A furostanol saponin from pepper (Capsicum annuum L.) seeds, suppresses adipogenesis through activation of AMP-activated protein kinase in 3T3-L1 cells
    • Sung J, Lee J. Capsicoside G, a furostanol saponin from pepper (Capsicum annuum L.) seeds, suppresses adipogenesis through activation of AMP-activated protein kinase in 3T3-L1 cells. J Funct Foods 2016; 20:148-158.
    • (2016) J Funct Foods , vol.20 , pp. 148-158
    • Sung, J.1    Lee, J.2    Capsicoside, G.3
  • 79
    • 84862283308 scopus 로고    scopus 로고
    • Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence
    • Whiting S, Derbyshire E, Tiwari BK. Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Appetite 2012; 59:341-348.
    • (2012) Appetite , vol.59 , pp. 341-348
    • Whiting, S.1    Derbyshire, E.2    Tiwari, B.K.3
  • 80
    • 3142512781 scopus 로고    scopus 로고
    • Maximum tolerable dose of red pepper decreases fat intake independently of spicy sensation in the mouth
    • Yoshioka M, Imanaga M, Ueyama H, Yamane M, Kubo Y, Boivin A, et al. Maximum tolerable dose of red pepper decreases fat intake independently of spicy sensation in the mouth. Br J Nut 2004; 91:991-995.
    • (2004) Br J Nut , vol.91 , pp. 991-995
    • Yoshioka, M.1    Imanaga, M.2    Ueyama, H.3    Yamane, M.4    Kubo, Y.5    Boivin, A.6
  • 81
    • 0032464789 scopus 로고    scopus 로고
    • Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women
    • Yoshioka M, St-Pierre S, Suzuki M, Tremblay A. Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women. Br J Nutr 199880:503-510.
    • Br J Nutr , pp. 503-510
    • Yoshioka, M.1    St-Pierre, S.2    Suzuki, M.3    Tremblay, A.4
  • 83
    • 67650888938 scopus 로고    scopus 로고
    • The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety
    • Smeets AJ, Westerterp-Plantenga MS. The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety. Eur J Nutr 2009; 48:229-234.
    • (2009) Eur J Nutr , vol.48 , pp. 229-234
    • Smeets, A.J.1    Westerterp-Plantenga, M.S.2
  • 84
    • 84871435182 scopus 로고    scopus 로고
    • Influence of red pepper spice and turmeric on inflammation and oxidative stress biomarkers in overweight females: A metabolomics approach
    • Nieman DC, Cialdella-Kam L, Knab AM, Shanely RA. Influence of red pepper spice and turmeric on inflammation and oxidative stress biomarkers in overweight females: a metabolomics approach. Plant Foods Hum Nutr 2012; 67:415-421.
    • (2012) Plant Foods Hum Nutr , vol.67 , pp. 415-421
    • Nieman, D.C.1    Cialdella-Kam, L.2    Knab, A.M.3    Shanely, R.A.4
  • 85
    • 0035464546 scopus 로고    scopus 로고
    • CH-19 sweet, a non-pungent cultivar of red pepper, increased body temperature and oxygen consumption in humans
    • Ohnuki K, Niwa S, Maeda S, Inoue N, Yazawa S, Fushiki T. CH-19 sweet, a non-pungent cultivar of red pepper, increased body temperature and oxygen consumption in humans. Biosci Biotechnol Biochem 20016; 5:2033-2036.
    • Biosci Biotechnol Biochem 20016 , vol.5 , pp. 2033-2036
    • Ohnuki, K.1    Niwa, S.2    Maeda, S.3    Inoue, N.4    Yazawa, S.5    Fushiki, T.6
  • 86
    • 33947584106 scopus 로고    scopus 로고
    • Effects of CH-19 Sweet, a non-pungent cultivar of red pepper, on sympathetic nervous activity, body temperature, heart rate, and blood pressure in humans
    • Hachiya S, Kawabata F, Ohnuki K, Inoue N, Yoneda H, Yazawa S, et al. Effects of CH-19 Sweet, a non-pungent cultivar of red pepper, on sympathetic nervous activity, body temperature, heart rate, and blood pressure in humans. Biosci Biotechnol Biochem 2007; 71:671-676.
    • (2007) Biosci Biotechnol Biochem , vol.71 , pp. 671-676
    • Hachiya, S.1    Kawabata, F.2    Ohnuki, K.3    Inoue, N.4    Yoneda, H.5    Yazawa, S.6
  • 87
    • 84898052002 scopus 로고    scopus 로고
    • Red peppers with different pungencies and bioactive compounds differentially modulate energy and glucose metabolism in ovariectomized rats fed high fat diets
    • Yang HJ, Kwon DY, Kim MJ, Kim DS, Kang S, Shin BK, et al. Red peppers with different pungencies and bioactive compounds differentially modulate energy and glucose metabolism in ovariectomized rats fed high fat diets. J Funct Foods 2014; 7:246-256.
    • (2014) J Funct Foods , vol.7 , pp. 246-256
    • Yang, H.J.1    Kwon, D.Y.2    Kim, M.J.3    Kim, D.S.4    Kang, S.5    Shin, B.K.6
  • 88
    • 0036234267 scopus 로고    scopus 로고
    • Pharmacological approaches for the treatment of obesity
    • Fernandez-Lopez JA, Remesar X, Foz M, Alemany M. Pharmacological approaches for the treatment of obesity. Drugs 2002; 62:915-944.
    • (2002) Drugs , vol.62 , pp. 915-944
    • Fernandez-Lopez, J.A.1    Remesar, X.2    Foz, M.3    Alemany, M.4


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