Red peppers with different pungencies and bioactive compounds differentially modulate energy and glucose metabolism in ovariectomized rats fed high fat diets

Journal of Functional Foods

Volumn 7, Issue 1, 2014, Pages 246-256

  Yang, Hye Jeong ^a   Kwon, Dae Young ^a   Kim, Min Jung ^a   Kim, Da Sol ^b   Kang, Suna ^b   Shin, Bae Keun ^b   Lee, Jung Ju ^b   Moon, Na Rang ^b   Daily, James W ^c   Park, Sunmin ^b  

^a Korea Food Research Institute   (South Korea)

^b Hoseo University   (South Korea)

^c Daily Manufacturing Inc   (United States)

Author keywords

Capsaicin; Hepatic insulin signaling; Oral glucose tolerance; Red pepper

Indexed keywords

CAPSICUM ANNUUM VAR. ANNUUM; RATTUS;

EID: 84898052002     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2014.02.004     Document Type: Article

References (49)

1. Ahuja K.D., Robertson I.K., Geraghty D.P., Ball M.J. Effects of chili consumption on postprandial glucose, insulin, and energy metabolism. American Journal of Clinical Nutrition 2006, 84:63-69.
2. Akiba Y., Kato S., Katsube K., Nakamura M., Takeuchi K., Ishii H., Hibi T. Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats. Biochemical and Biophysical Research Communications 2004, 321:219-225.
3. Alevizos A., Mihasm C., Mariolis A., Larios G. Insulin secretion and capsaicin. American Journal of Clinical Nutrition 2007, 8:1165-1166.
4. Alvarez-Parrilla E., de la Rosa L.A., Amarowicz R., Shahidi F. Antioxidant activity of fresh and processed Jalapeño and Serrano peppers. Journal of Agricultural Food Chemistry 2011, 59:163-173.
5. Bernhardt S., Schlich E. Impact of different cooking methods on food quality: Retention of lipophilic vitamins in fresh and frozen vegetables. Journal of Food Engineering 2006, 77:327-333.
6. Berryman A.M., Maritim A.C., Sanders R.A., Watkins J.B. Influence of treatment of diabetic rats with combinations of pycnogenol, beta-carotene, and alpha-lipoic acid on parameters of oxidative stress. Journal of Biochemical and Molecular Toxicology 2004, 18:345-352.
7. Butera P.C. Estradiol and the control of food intake. Physiology & Behavior 2010, 99:175-180.
8. Canas J.A., Damaso L., Altomare A., Killen K., Hossain J., Balagopal P.B. Insulin resistance and adiposity in relation to serum β-carotene levels. Journal of Pediatrics 2012, 161:58-64.
9. Chen L., Kang Y.W. Anti-inflammatory and antioxidant activities of red pepper (Capsicum annuum L.) stalk extracts: Comparison of pericarp and placenta extracts. Journal of Functional Foods 2013, 5:1724-1731.
10. Choi S.B., Jang J.S., Park S. Estrogen and exercise may enhance beta-cell function and mass via insulin receptor substrate 2 induction in ovariectomized diabetic rats. Endocrinology 2005, 146:4786-47904.
11. Clarke S.D., Clarke I.J., Rao A., Evans R.G., Henry B.A. Differential effects of acute and chronic estrogen treatment on thermogenic and metabolic pathways in ovariectomized sheep. Endocrinology 2013, 154:184-192.
12. Cristino L., de Petrocellis L., Pryce G., Baker D., Guglielmotti V., Di Marzo V. Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience 2006, 139:1405-1415.
13. Davis W.B. Determination of flavanones in citrus fruits. Analytical Chemistry 1947, 19:476-477.
14. Dong X., Park S., Lin X., Copps K., Yi X., White M.F. Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth. Journal of Clinical Investigation 2006, 116:101-114.
15. Flegal K.M., Carroll M.D., Kit B.K., Ogden C.L. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. Journal of American Medical Association 2012, 307:491-497.
16. Frontoni S., Choi S.B., Banduch D., Rossetti L. In vivo insulin resistance induced by amylin primarily through inhibition of insulin-stimulated glycogen synthesis in skeletal muscle. Diabetes 1991, 40:568-573.
17. Gao H., Miyata K., Bhaskaran M.D., Derbenev A.V., Zsombok A. Transient receptor potential vanilloid type 1-dependent regulation of liver-related neurons in the paraventricular nucleus of the hypothalamus diminished in the type 1 diabetic mouse. Diabetes 2012, 61:1381-1390.
18. Hardie D.G., Ross F.A., Hawley S.A. AMPK: A nutrient and energy sensor that maintains energy homeostasis. Nature Review Molecular Cell Biology 2012, 13:251-262.
19. Henry C.J., Emery B. Effect of spiced food on metabolic rate. Human Nutrition. Clinical Nutrition 1986, 40:165-168.
20. Janssens P.L., Hursel R., Martens E.A., Westerterp-Plantenga M.S. Acute effects of capsaicin on energy expenditure and fat oxidation in negative energy balance. PLoS One 2013, 8:e67786.
21. Jhala U.S., Canettieri G., Screaton R.A., Kulkarni R.N., Krajewski S., Reed J., Walker J., Lin X., White M., Montminy M. CAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes & Development 2003, 17:1575-1580.
22. Jones M.E., Thorburn A.W., Britt K.L., Hewitt K.N., Misso M.L., Wreford N.G., Proietto J., Oz O.K., Leury B.J., Robertson K.M., Yao S., Simpson E.R. Aromatase-deficient (ArKO) mice accumulate excess adipose tissue. Journal of Steroid Biochemistry and Molecular Biology 2001, 79:3-9.
23. Karlsson S., Scheurink A.J., Steffens A.B., Ahren B. Involvement of capsaicin-sensitive nerves in regulation of insulin secretion and glucose tolerance in conscious mice. American Journal of Physiology 1994, 267:R1071-R1077.
24. Kim S.Y., Park G.M. Relationship between red pepper intake, capsaicin threshold, nutrient intake, and anthropometric measurements in young Korean women. Korean Journal of Nutrition 2005, 38:76-81.
25. Krotkiewski M., Bjorntorp P., Sjostrom L., Smith U. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. Journal of Clinical Investigation 1983, 72:1150-1162.
26. Kwon D.Y., Kim Y.S., Ryu S.Y., Cha M.R., Yon G.H., Yang H.J., Kim M.J., Kang S., Park S. Capsiate improves glucose metabolism by improving insulin sensitivity better than capsaicin in diabetic rats. Journal of Nutritional Biochemistry 2013, 24:1078-1085.
27. Lobo G.P., Amengual J., Li H.N., Golczak M., Bonet M.L., Palczewski K., von Lintig J. Beta, beta-carotene decreases peroxisome proliferator receptor gamma activity and reduces lipid storage capacity of adipocytes in a beta, beta-carotene oxygenase 1-dependent manner. Journal of Biological Chemistry 2010, 285:27891-27899.
28. Matsumoto T., Miyawaki C., Ue H., Yuasa T., Miyatsuji A., Moritani T. Effects of capsaicin-containing yellow curry sauce on sympathetic nervous system activity and diet-induced thermogenesis in lean and obese young women. Journal of Nutritional Science and Vitaminology (Tokyo) 2000, 46:309-315.
29. Mauvais-Jarvis F. Estrogen and androgen receptors: Regulators of fuel homeostasis and emerging targets for diabetes and obesity. Trends in Endocrinology & Metabolism 2011, 22:24-33.
30. Mezey E., Toth Z.E., Cortright D.N., Arzubi M.K., Krause J.E., Elde R., Guo A., Blumberg P.M., Szallasi A. Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human. Proceedings of the National Academy of Science United States of America 2000, 97:3655-3660.
31. Park S., Hong S.M., Ahn I.L., Kim D.S., Kim S.H. Estrogen replacement reverses olanzapine-induced weight gain and hepatic insulin resistance in ovariectomized diabetic rats. Neuropsychobiology 2010, 61:148-161.
32. Park S., Hong S.M., Lee J.E., Sung S.R. Exercise improves glucose homeostasis that has been impaired by a high-fat diet by potentiating pancreatic beta-cell function and mass through IRS2 in diabetic rats. Journal of Applied Physiology 2007, 103:1764-1771.
33. Park S., Kim D.S., Kang S. Gastrodia elata Blume water extracts improve insulin resistance by decreasing body fat in diet-induced obese rats: Vanillin and 4-hydroxybenzaldehyde are the bioactive candidates. European Journal Nutrition 2011, 50:107-118.
34. Poehlman E.T., Toth M.J., Gardner A.W. Changes in energy balance and body composition at menopause: A controlled longitudinal study. Annual Internal Medicine 1995, 123:673-675.
35. Reeves P.G., Nielsen F.H., Fahey G.C. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. Journal of Nutrition 1993, 123:1939-1951.
36. Rhee S.Y., Park S.W., Kim D.J., Woo J. Gender disparity in the secular trends for obesity prevalence in Korea: Analyses based on the KNHANES 1998-2009. Korean Journal of Internal Medicine 2013, 28:29-34.
37. Ritter E., Purcell A.E. Appendix: Absorption maxina and E1%1mL values for carotenoids. Carotenoids as colorants and vitamin a precursors, technological and nutritional applications 1981, 888. Academic Press, New York. J.S. Bauernfeind (Ed.).
38. Rosenbaum T., Simon S.A. TRPV1 receptors and signal transduction. TRP ion channel function in sensory transduction and cellular signaling cascades 2007, CRC Press, Boca Raton, (Chapter 5). W.B. Liedtke, S. Heller (Eds.).
39. Saito M., Yoneshiro T. Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans. Current Opinion in Lipidology 2013, 24:71-77.
40. Santollo J., Wiley M.D., Eckel L.A. Acute activation of ER alpha decreases food intake, meal size, and body weight in ovariectomized rats. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2007, 293:R2194-R2201.
41. Singleton V.L., Orthofer R., Lamuela-Raventós R.M. Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. Methods in Enzymology 1999, 299:152-178.
42. Sisley S., Sandoval D. Hypothalamic control of energy and glucose metabolism. Review in Endocrine and Metabolic Disorders 2011, 12:219-233.
43. Snitker S., Fujishima Y., Shen H., Ott S., Pi-Sunyer X., Furuhata Y., Sato H., Takahashi M. Effects of novel capsinoid treatment on fatness and energy metabolism in humans: Possible pharmacogenetic implications. American Journal of Clinical Nutrition 2009, 89:45-50.
44. Suzuki K., Inoue T., Hioki R., Ochiai J., Kusuhara Y., Ichino N., Osakabe K., Hamajima N., Ito Y. Association of abdominal obesity with decreased serum levels of carotenoids in a healthy Japanese population. Clinical Nutrition 2006, 25:780-789.
45. Yang H.J., Jang D.J., Hwang J.T. Anti-diabetic effects of Korean red pepper via AMPK and PPAR-γ activation in C2C12 myotubes. Journal of Functional Foods 2012, 4:552-558.
46. Yoshioka M., Imanaga M., Ueyama H., Yamane M., Kubo Y., Boivin A., St-Amand J., Tanaka H., Kiyonaga A. Maximum tolerable dose of red pepper decreases fat intake independently of spicy sensation in the mouth. British Journal of Nutrition 2004, 91:991-995.
47. Yoshioka M., St-Pierre S., Drapeau V., Dionne I., Doucet E., Suzuki M., Tremblay A. Effects of red pepper on appetite and energy intake. British Journal of Nutrition 1999, 82:115-123.
48. Yu Q., Wang Y., Yu Y., Li Y., Zhao S., Chen Y., Waqar A.B., Fan J., Liu E. Expression of TRPV1 in rabbits and consuming hot pepper affects its body weight. Molecular Biology Reports 2012, 39:7583-7589.
49. Zsomboka A., Gao H., Miyataa K., Issaa A., Derbeneva A.V. Immunohistochemical localization of transient receptor potential vanilloid type 1 and insulin receptor substrate 2 and their co-localization with liver-related neurons in the hypothalamus and brainstem. Brain Research 2011, 1398:30-39.