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Volumn 8, Issue 5, 2016, Pages

Dietary capsaicin protects cardiometabolic organs from dysfunction

Author keywords

Capsaicin; Chili pepper; Diabetes; Hypertension; Metabolic syndrome; Obesity; TRPV1

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CHOLECYSTOKININ; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GHRELIN; GLUCAGON LIKE PEPTIDE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; PEPTIDE YY; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; VANILLOID RECEPTOR 1; TRPV1 PROTEIN, HUMAN; VANILLOID RECEPTOR;

EID: 85012822925     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu8050174     Document Type: Review
Times cited : (98)

References (89)
  • 1
    • 84988372343 scopus 로고    scopus 로고
    • 4(alpha-l-rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that defends cerebral tissue and prevents severe damage induced by focal ischemia/reperfusion
    • [PubMed]
    • Galuppo, M.; Giacoppo, S.; Iori, R.; De Nicola, G.R.; Milardi, D.; Bramanti, P.; Mazzon, E. 4(alpha-l-rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that defends cerebral tissue and prevents severe damage induced by focal ischemia/reperfusion. J. Biol. Regul. Homeost. Agents 2015, 29, 343-356. [PubMed]
    • (2015) J. Biol. Regul. Homeost. Agents , vol.29 , pp. 343-356
    • Galuppo, M.1    Giacoppo, S.2    Iori, R.3    De Nicola, G.R.4    Milardi, D.5    Bramanti, P.6    Mazzon, E.7
  • 3
    • 84959299617 scopus 로고    scopus 로고
    • Protective effect of ginger and zinc chloride mixture on the liver and kidney alterations induced by malathion toxicity
    • [CrossRef] [PubMed]
    • Baiomy, A.A.; Attia, H.F.; Soliman, M.M.; Makrum, O. Protective effect of ginger and zinc chloride mixture on the liver and kidney alterations induced by malathion toxicity. Int. J. Immunopathol. Pharmacol. 2015, 28, 122-128. [CrossRef] [PubMed]
    • (2015) Int. J. Immunopathol. Pharmacol , vol.28 , pp. 122-128
    • Baiomy, A.A.1    Attia, H.F.2    Soliman, M.M.3    Makrum, O.4
  • 4
  • 6
    • 77955569436 scopus 로고    scopus 로고
    • Transient receptor potential channelopathies
    • [CrossRef] [PubMed]
    • Nilius, B.; Owsianik, G. Transient receptor potential channelopathies. Pflügers Arch. 2010, 460, 437-450. [CrossRef] [PubMed]
    • (2010) Pflügers Arch , vol.460 , pp. 437-450
    • Nilius, B.1    Owsianik, G.2
  • 7
    • 33846807748 scopus 로고    scopus 로고
    • Transient receptor potential cation channels in disease
    • [CrossRef] [PubMed]
    • Nilius, B.; Owsianik, G.; Voets, T.; Peters, J.A. Transient receptor potential cation channels in disease. Physiol. Rev. 2007, 87, 165-217. [CrossRef] [PubMed]
    • (2007) Physiol. Rev , vol.87 , pp. 165-217
    • Nilius, B.1    Owsianik, G.2    Voets, T.3    Peters, J.A.4
  • 8
    • 0021351360 scopus 로고
    • Gastrointestinal absorption and metabolism of capsaicin and dihydrocapsaicin in rats
    • [CrossRef]
    • Kawada, T.; Suzuki, T.; Takahashi, M.; Iwai, K. Gastrointestinal absorption and metabolism of capsaicin and dihydrocapsaicin in rats. Toxicol. Appl. Pharmacol. 1984, 72, 449-456. [CrossRef]
    • (1984) Toxicol. Appl. Pharmacol , vol.72 , pp. 449-456
    • Kawada, T.1    Suzuki, T.2    Takahashi, M.3    Iwai, K.4
  • 9
    • 68049102284 scopus 로고    scopus 로고
    • Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: High abundance and sensitivity in rectum and distal colon
    • [CrossRef] [PubMed]
    • Matsumoto, K.; Kurosawa, E.; Terui, H.; Hosoya, T.; Tashima, K.; Murayama, T.; Priestley, J.V.; Horie, S. Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: High abundance and sensitivity in rectum and distal colon. Am. J. Physiol. Gastrointest. Liver Physiol. 2009, 297, G348-G360. [CrossRef] [PubMed]
    • (2009) Am. J. Physiol. Gastrointest. Liver Physiol , vol.297 , pp. G348-G360
    • Matsumoto, K.1    Kurosawa, E.2    Terui, H.3    Hosoya, T.4    Tashima, K.5    Murayama, T.6    Priestley, J.V.7    Horie, S.8
  • 10
    • 78751644062 scopus 로고    scopus 로고
    • Trp channels and their implications in metabolic diseases
    • [CrossRef] [PubMed]
    • Zhu, Z.; Luo, Z.; Ma, S.; Liu, D. Trp channels and their implications in metabolic diseases. Pflügers Arch. 2011, 461, 211-223. [CrossRef] [PubMed]
    • (2011) Pflügers Arch , vol.461 , pp. 211-223
    • Zhu, Z.1    Luo, Z.2    Ma, S.3    Liu, D.4
  • 11
    • 34248138496 scopus 로고    scopus 로고
    • The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
    • [CrossRef] [PubMed]
    • Szallasi, A.; Cortright, D.N.; Blum, C.A.; Eid, S.R. The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat. Rev. Drug Discov. 2007, 6, 357-372. [CrossRef] [PubMed]
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 357-372
    • Szallasi, A.1    Cortright, D.N.2    Blum, C.A.3    Eid, S.R.4
  • 12
    • 84924282820 scopus 로고    scopus 로고
    • Activation of TRPV1 channel by dietary capsaicin improves visceral fat remodeling through connexin43-mediated Ca influx
    • [CrossRef] [PubMed]
    • Chen, J.; Li, L.; Li, Y.; Liang, X.; Sun, Q.; Yu, H.; Zhong, J.; Ni, Y.; Chen, J.; Zhao, Z. Activation of TRPV1 channel by dietary capsaicin improves visceral fat remodeling through connexin43-mediated Ca influx. Cardiovasc. Diabetol. 2015, 14, 1-14. [CrossRef] [PubMed]
    • (2015) Cardiovasc. Diabetol , vol.14 , pp. 1-14
    • Chen, J.1    Li, L.2    Li, Y.3    Liang, X.4    Sun, Q.5    Yu, H.6    Zhong, J.7    Ni, Y.8    Chen, J.9    Zhao, Z.10
  • 13
    • 84901199988 scopus 로고    scopus 로고
    • Capsaicin as new orally applicable gastroprotective and therapeutic drug alone or in combination with nonsteroidal anti-inflammatory drugs in healthy human subjects and in patients
    • [PubMed]
    • Mózsik, G. Capsaicin as new orally applicable gastroprotective and therapeutic drug alone or in combination with nonsteroidal anti-inflammatory drugs in healthy human subjects and in patients. Prog. Drug Res. 2014, 68, 209-258. [PubMed]
    • (2014) Prog. Drug Res , vol.68 , pp. 209-258
    • Mózsik, G.1
  • 14
    • 78049443064 scopus 로고    scopus 로고
    • Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension
    • [CrossRef] [PubMed]
    • Yang, D.; Luo, Z.; Ma, S.; Wong, W.T.; Ma, L.; Zhong, J.; He, H.; Zhao, Z.; Cao, T.; Yan, Z.; et al. Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension. Cell Metab. 2010, 12, 130-141. [CrossRef] [PubMed]
    • (2010) Cell Metab , vol.12 , pp. 130-141
    • Yang, D.1    Luo, Z.2    Ma, S.3    Wong, W.T.4    Ma, L.5    Zhong, J.6    He, H.7    Zhao, Z.8    Cao, T.9    Yan, Z.10
  • 15
    • 41549105257 scopus 로고    scopus 로고
    • Increased gfr and renal excretory function by activation of TRPV1 in the isolated perfused kidney
    • [CrossRef] [PubMed]
    • Li, J.; Wang, D.H. Increased gfr and renal excretory function by activation of TRPV1 in the isolated perfused kidney. Pharmacol. Res. 2008, 57, 239-246. [CrossRef] [PubMed]
    • (2008) Pharmacol. Res , vol.57 , pp. 239-246
    • Li, J.1    Wang, D.H.2
  • 16
    • 44649179101 scopus 로고    scopus 로고
    • Segmental regulation of sodium and water excretion by TRPV1 activation in the kidney
    • [CrossRef] [PubMed]
    • Zhu, Y.; Wang, D.H. Segmental regulation of sodium and water excretion by TRPV1 activation in the kidney. J. Cardiovasc. Pharmacol. 2008, 51, 437-442. [CrossRef] [PubMed]
    • (2008) J. Cardiovasc. Pharmacol , vol.51 , pp. 437-442
    • Zhu, Y.1    Wang, D.H.2
  • 18
    • 80155154452 scopus 로고    scopus 로고
    • Comparison of sensory, physiological, personality, and cultural attributes in regular spicy food users and non-users
    • [CrossRef] [PubMed]
    • Ludy, M.J.; Mattes, R.D. Comparison of sensory, physiological, personality, and cultural attributes in regular spicy food users and non-users. Appetite 2012, 58, 19-27. [CrossRef] [PubMed]
    • (2012) Appetite , vol.58 , pp. 19-27
    • Ludy, M.J.1    Mattes, R.D.2
  • 19
    • 84864377753 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1 activation enhances gut glucagon-like peptide-1 secretion and improves glucose homeostasis
    • [CrossRef] [PubMed]
    • Wang, P.; Yan, Z.; Zhong, J.; Chen, J.; Ni, Y.; Li, L.; Ma, L.; Zhao, Z.; Liu, D.; Zhu, Z. Transient receptor potential vanilloid 1 activation enhances gut glucagon-like peptide-1 secretion and improves glucose homeostasis. Diabetes 2012, 61, 2155-2165. [CrossRef] [PubMed]
    • (2012) Diabetes , vol.61 , pp. 2155-2165
    • Wang, P.1    Yan, Z.2    Zhong, J.3    Chen, J.4    Ni, Y.5    Li, L.6    Ma, L.7    Zhao, Z.8    Liu, D.9    Zhu, Z.10
  • 20
    • 33846194056 scopus 로고    scopus 로고
    • Capsaicin-sensitive sensory fibers in the islets of langerhans contribute to defective insulin secretion in zucker diabetic rat, an animal model for some aspects of human type2 diabetes
    • [CrossRef] [PubMed]
    • Gram, D.X.; Bo, A.; Istvan, N.; Olsen, U.B.; Brand, C.L.; Frank, S.; René, T.; Ove, S.; Carr, R.D.; Peter, S. Capsaicin-sensitive sensory fibers in the islets of langerhans contribute to defective insulin secretion in zucker diabetic rat, an animal model for some aspects of human type2 diabetes. Eur. J. Neurosci. 2007, 25, 213-223. [CrossRef] [PubMed]
    • (2007) Eur. J. Neurosci , vol.25 , pp. 213-223
    • Gram, D.X.1    Bo, A.2    Istvan, N.3    Olsen, U.B.4    Brand, C.L.5    Frank, S.6    René, T.7    Ove, S.8    Carr, R.D.9    Peter, S.10
  • 21
    • 14044260472 scopus 로고    scopus 로고
    • Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in zucker diabetic fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase iv
    • [CrossRef] [PubMed]
    • Gram, D.X.; Hansen, A.J.; Deacon, C.F.; Brand, C.L.; Ribel, U.;Wilken, M.; Carr, R.D.; Svendsen, O.; Bo, A. Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in zucker diabetic fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase iv. Eur. J. Pharmacol. 2005, 509, 211-217. [CrossRef] [PubMed]
    • (2005) Eur. J. Pharmacol , vol.509 , pp. 211-217
    • Gram, D.X.1    Hansen, A.J.2    Deacon, C.F.3    Brand, C.L.4    Ribel, U.5    Wilken, M.6    Carr, R.D.7    Svendsen, O.8    Bo, A.9
  • 23
    • 84957630515 scopus 로고    scopus 로고
    • The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells
    • Ramos-Torres, A.; Bort, A.; Morell, C.; Rodriguez-Henche, N.; Diaz-Laviada, I. The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells. Oncotarget 2015, 7, 1569-1583.
    • (2015) Oncotarget , vol.7 , pp. 1569-1583
    • Ramos-Torres, A.1    Bort, A.2    Morell, C.3    Rodriguez-Henche, N.4    Diaz-Laviada, I.5
  • 25
    • 77649187285 scopus 로고    scopus 로고
    • Capsaicin mediates cell death in bladder cancer t24 cells through reactive oxygen species production and mitochondrial depolarization
    • [CrossRef] [PubMed]
    • Yang, Z.H.; Wang, X.H.; Wang, H.P.; Hu, L.Q.; Zheng, X.M.; Li, S.W. Capsaicin mediates cell death in bladder cancer t24 cells through reactive oxygen species production and mitochondrial depolarization. Urology 2010, 75, 735-741. [CrossRef] [PubMed]
    • (2010) Urology , vol.75 , pp. 735-741
    • Yang, Z.H.1    Wang, X.H.2    Wang, H.P.3    Hu, L.Q.4    Zheng, X.M.5    Li, S.W.6
  • 27
    • 34548399748 scopus 로고    scopus 로고
    • Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese-mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages
    • [CrossRef] [PubMed]
    • Kang, J.H.; Kim, C.S.; Han, I.S.; Kawada, T.; Yu, R. Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese-mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages. FEBS Lett. 2007, 581, 4389-4396. [CrossRef] [PubMed]
    • (2007) FEBS Lett , vol.581 , pp. 4389-4396
    • Kang, J.H.1    Kim, C.S.2    Han, I.S.3    Kawada, T.4    Yu, R.5
  • 28
    • 34247168128 scopus 로고    scopus 로고
    • Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity
    • [CrossRef] [PubMed]
    • Zhang, L.L.; Yan Liu, D.; Ma, L.Q.; Luo, Z.D.; Cao, T.B.; Zhong, J.; Yan, Z.C.; Wang, L.J.; Zhao, Z.G.; Zhu, S.J.; et al. Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity. Circ. Res. 2007, 100, 1063-1070. [CrossRef] [PubMed]
    • (2007) Circ. Res , vol.100 , pp. 1063-1070
    • Zhang, L.L.1    Yan Liu, D.2    Ma, L.Q.3    Luo, Z.D.4    Cao, T.B.5    Zhong, J.6    Yan, Z.C.7    Wang, L.J.8    Zhao, Z.G.9    Zhu, S.J.10
  • 29
    • 84890125300 scopus 로고    scopus 로고
    • Mechanisms and clinical uses of capsaicin
    • [CrossRef] [PubMed]
    • Sharma, S.K.; Vij, A.S.; Sharma, M. Mechanisms and clinical uses of capsaicin. Eur. J. Pharmacol. 2013, 720, 55-62. [CrossRef] [PubMed]
    • (2013) Eur. J. Pharmacol , vol.720 , pp. 55-62
    • Sharma, S.K.1    Vij, A.S.2    Sharma, M.3
  • 30
    • 77954582014 scopus 로고    scopus 로고
    • Proteomic analysis for antiobesity potential of capsaicin on white adipose tissue in rats fed with a high fat diet
    • [CrossRef] [PubMed]
    • Joo, J.I.; Kim, D.H.; Choi, J.W.; Yun, J.W. Proteomic analysis for antiobesity potential of capsaicin on white adipose tissue in rats fed with a high fat diet. J. Proteome Res. 2010, 9, 2977-2987. [CrossRef] [PubMed]
    • (2010) J. Proteome Res , vol.9 , pp. 2977-2987
    • Joo, J.I.1    Kim, D.H.2    Choi, J.W.3    Yun, J.W.4
  • 31
    • 84946485799 scopus 로고    scopus 로고
    • Food ingredients as anti-obesity agents
    • [CrossRef] [PubMed]
    • Saito, M.; Yoneshiro, T.; Matsushita, M. Food ingredients as anti-obesity agents. Trends Endocrinol. Metab. 2015, 26, 585-587. [CrossRef] [PubMed]
    • (2015) Trends Endocrinol. Metab , vol.26 , pp. 585-587
    • Saito, M.1    Yoneshiro, T.2    Matsushita, M.3
  • 32
    • 79954620647 scopus 로고    scopus 로고
    • Intragastric administration of capsiate, a transient receptor potential channel agonist, triggers thermogenic sympathetic responses
    • [CrossRef] [PubMed]
    • Ono, K.; Tsukamoto-Yasui, M.; Hara-Kimura, Y.; Inoue, N.; Nogusa, Y.; Okabe, Y.; Nagashima, K.; Kato, F. Intragastric administration of capsiate, a transient receptor potential channel agonist, triggers thermogenic sympathetic responses. J. Appl. Physiol. 2011, 110, 789-798. [CrossRef] [PubMed]
    • (2011) J. Appl. Physiol , vol.110 , pp. 789-798
    • Ono, K.1    Tsukamoto-Yasui, M.2    Hara-Kimura, Y.3    Inoue, N.4    Nogusa, Y.5    Okabe, Y.6    Nagashima, K.7    Kato, F.8
  • 34
    • 17844392649 scopus 로고    scopus 로고
    • Oleoylethanolamide excites vagal sensory neurones, induces visceral pain and reduces short-term food intake in mice via capsaicin receptor TRPV1
    • [CrossRef] [PubMed]
    • Wang, X.; Miyares, R.L.; Ahern, G.P. Oleoylethanolamide excites vagal sensory neurones, induces visceral pain and reduces short-term food intake in mice via capsaicin receptor TRPV1. J. Physiol. 2005, 564, 541-547. [CrossRef] [PubMed]
    • (2005) J. Physiol , vol.564 , pp. 541-547
    • Wang, X.1    Miyares, R.L.2    Ahern, G.P.3
  • 35
    • 34249300871 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1 antagonist, capsazepine, improves survival in a rat hemorrhagic shock model
    • [CrossRef] [PubMed]
    • Akabori, H.; Yamamoto, H.; Tsuchihashi, H.; Mori, T.; Fujino, K.; Shimizu, T.; Endo, Y.; Tani, T. Transient receptor potential vanilloid 1 antagonist, capsazepine, improves survival in a rat hemorrhagic shock model. Ann. Surg. 2007, 245, 964-970. [CrossRef] [PubMed]
    • (2007) Ann. Surg , vol.245 , pp. 964-970
    • Akabori, H.1    Yamamoto, H.2    Tsuchihashi, H.3    Mori, T.4    Fujino, K.5    Shimizu, T.6    Endo, Y.7    Tani, T.8
  • 36
    • 79953849199 scopus 로고    scopus 로고
    • Proteomic analysis of liver proteins in rats fed with a high-fat diet in response to capsaicin treatments
    • [CrossRef]
    • Choi, J.W.; Hwang, H.S.; Dong, H.K.; Joo, J.I.; Yun, J.W. Proteomic analysis of liver proteins in rats fed with a high-fat diet in response to capsaicin treatments. Biotechnol. Bioprocess Eng. 2010, 15, 534-544. [CrossRef]
    • (2010) Biotechnol. Bioprocess Eng , vol.15 , pp. 534-544
    • Choi, J.W.1    Hwang, H.S.2    Dong, H.K.3    Joo, J.I.4    Yun, J.W.5
  • 37
    • 84862807525 scopus 로고    scopus 로고
    • TRPV1 activation prevents nonalcoholic fatty liver through ucp2 upregulation in mice
    • [CrossRef] [PubMed]
    • Li, L.; Chen, J.; Ni, Y.; Feng, X.; Zhao, Z.; Wang, P.; Sun, J.; Yu, H.; Yan, Z.; Liu, D. TRPV1 activation prevents nonalcoholic fatty liver through ucp2 upregulation in mice. Pflügers Arch. 2012, 463, 727-732. [CrossRef] [PubMed]
    • (2012) Pflügers Arch , vol.463 , pp. 727-732
    • Li, L.1    Chen, J.2    Ni, Y.3    Feng, X.4    Zhao, Z.5    Wang, P.6    Sun, J.7    Yu, H.8    Yan, Z.9    Liu, D.10
  • 38
    • 84876294971 scopus 로고    scopus 로고
    • Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice
    • [CrossRef] [PubMed]
    • Lee, G.R.; Shin, M.K.; Yoon, D.J.; Kim, A.R.; Yu, R.; Park, N.H.; Han, I.S. Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice. Obesity 2013, 21, 115-122. [CrossRef] [PubMed]
    • (2013) Obesity , vol.21 , pp. 115-122
    • Lee, G.R.1    Shin, M.K.2    Yoon, D.J.3    Kim, A.R.4    Yu, R.5    Park, N.H.6    Han, I.S.7
  • 39
    • 77950187437 scopus 로고    scopus 로고
    • Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet
    • [CrossRef] [PubMed]
    • Kang, J.H.; Goto, T.; Han, I.S.; Kawada, T.; Kim, Y.M.; Yu, R. Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet. Obesity 2010, 18, 780-787. [CrossRef] [PubMed]
    • (2010) Obesity , vol.18 , pp. 780-787
    • Kang, J.H.1    Goto, T.2    Han, I.S.3    Kawada, T.4    Kim, Y.M.5    Yu, R.6
  • 40
    • 44749085444 scopus 로고    scopus 로고
    • TRPV1-null mice are protected from diet-induced obesity
    • [CrossRef] [PubMed]
    • Motter, A.L.; Ahern, G.P. TRPV1-null mice are protected from diet-induced obesity. FEBS Lett. 2008, 582, 2257-2262. [CrossRef] [PubMed]
    • (2008) FEBS Lett , vol.582 , pp. 2257-2262
    • Motter, A.L.1    Ahern, G.P.2
  • 41
    • 84940390559 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance
    • [CrossRef] [PubMed]
    • Lee, E.; Jung, D.Y.; Kim, J.H.; Patel, P.R.; Hu, X.D.; Lee, Y.; Azuma, Y.; Wang, H.F.; Tsitsilianos, N.; Shafiq, U.; et al. Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance. FASEB J. 2015, 29, 3182-3192. [CrossRef] [PubMed]
    • (2015) FASEB J , vol.29 , pp. 3182-3192
    • Lee, E.1    Jung, D.Y.2    Kim, J.H.3    Patel, P.R.4    Hu, X.D.5    Lee, Y.6    Azuma, Y.7    Wang, H.F.8    Tsitsilianos, N.9    Shafiq, U.10
  • 42
    • 3543040629 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats
    • [CrossRef] [PubMed]
    • Akiba, Y.; Kato, S.; Katsube, K.; Nakamura, M.; Takeuchi, K.; Ishii, H.; Hibi, T. Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats. Biochem. Biophys. Res. Commun. 2004, 321, 219-225. [CrossRef] [PubMed]
    • (2004) Biochem. Biophys. Res. Commun , vol.321 , pp. 219-225
    • Akiba, Y.1    Kato, S.2    Katsube, K.3    Nakamura, M.4    Takeuchi, K.5    Ishii, H.6    Hibi, T.7
  • 44
    • 84878014185 scopus 로고    scopus 로고
    • Capsiate improves glucose metabolism by improving insulin sensitivity better than capsaicin in diabetic rats
    • [CrossRef] [PubMed]
    • Kwon, D.Y.; Kim, Y.S.; Shi, Y.R.; Cha, M.R.; Yon, G.H.; Yang, H.J.; Min, J.K.; Kang, S.; Park, S. Capsiate improves glucose metabolism by improving insulin sensitivity better than capsaicin in diabetic rats. J. Nutr. Biochem. 2013, 24, 1078-1085. [CrossRef] [PubMed]
    • (2013) J. Nutr. Biochem , vol.24 , pp. 1078-1085
    • Kwon, D.Y.1    Kim, Y.S.2    Shi, Y.R.3    Cha, M.R.4    Yon, G.H.5    Yang, H.J.6    Min, J.K.7    Kang, S.8    Park, S.9
  • 46
    • 61349089794 scopus 로고    scopus 로고
    • Increased trpc3 expression in vascular endothelium of patients with malignant hypertension
    • [CrossRef] [PubMed]
    • Thilo, F.; Loddenkemper, C.; Berg, E.; Zidek,W.; Tepel, M. Increased trpc3 expression in vascular endothelium of patients with malignant hypertension. Mod. Pathol. 2009, 22, 426-430. [CrossRef] [PubMed]
    • (2009) Mod. Pathol , vol.22 , pp. 426-430
    • Thilo, F.1    Loddenkemper, C.2    Berg, E.3    Zidek, W.4    Tepel, M.5
  • 47
    • 58149393175 scopus 로고    scopus 로고
    • Increased transient receptor potential canonical type 3 channels in vasculature from hypertensive rats
    • [CrossRef] [PubMed]
    • Liu, D.; Yang, D.; He, H.; Chen, X.; Cao, T.; Feng, X.; Ma, L.; Luo, Z.; Wang, L.; Yan, Z.; et al. Increased transient receptor potential canonical type 3 channels in vasculature from hypertensive rats. Hypertension 2009, 53, 70-76. [CrossRef] [PubMed]
    • (2009) Hypertension , vol.53 , pp. 70-76
    • Liu, D.1    Yang, D.2    He, H.3    Chen, X.4    Cao, T.5    Feng, X.6    Ma, L.7    Luo, Z.8    Wang, L.9    Yan, Z.10
  • 48
    • 23844457669 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide and hypertension
    • [CrossRef] [PubMed]
    • Deng, P.Y.; Li, Y.J. Calcitonin gene-related peptide and hypertension. Peptides 2005, 26, 1676-1685. [CrossRef] [PubMed]
    • (2005) Peptides , vol.26 , pp. 1676-1685
    • Deng, P.Y.1    Li, Y.J.2
  • 49
    • 58549097507 scopus 로고    scopus 로고
    • Relaxation evoked by extracellular Ca2+ in rat aorta is nerve-independent and involves sarcoplasmic reticulum and l-type Ca2+channel
    • [CrossRef] [PubMed]
    • Rocha, M.; Bendhack, L. Relaxation evoked by extracellular Ca2+ in rat aorta is nerve-independent and involves sarcoplasmic reticulum and l-type Ca2+channel. Vasc. Pharmacol. 2009, 50, 98-103. [CrossRef] [PubMed]
    • (2009) Vasc. Pharmacol , vol.50 , pp. 98-103
    • Rocha, M.1    Bendhack, L.2
  • 50
    • 33644987046 scopus 로고    scopus 로고
    • A novel mechanism contributing to development of dahl salt-sensitive hypertension: Role of the transient receptor potential vanilloid type 1
    • [CrossRef] [PubMed]
    • Wang, Y.; Wang, D.H. A novel mechanism contributing to development of dahl salt-sensitive hypertension: Role of the transient receptor potential vanilloid type 1. Hypertension 2006, 47, 609-614. [CrossRef] [PubMed]
    • (2006) Hypertension , vol.47 , pp. 609-614
    • Wang, Y.1    Wang, D.H.2
  • 51
    • 79953762321 scopus 로고    scopus 로고
    • TRPV1 activation prevents high-salt diet-induced nocturnal hypertension in mice
    • [CrossRef] [PubMed]
    • Hao, X.; Chen, J.; Luo, Z.; He, H.; Yu, H.; Ma, L.; Ma, S.; Zhu, T.; Liu, D.; Zhu, Z. TRPV1 activation prevents high-salt diet-induced nocturnal hypertension in mice. Pflugers Arch. 2011, 461, 345-353. [CrossRef] [PubMed]
    • (2011) Pflugers Arch , vol.461 , pp. 345-353
    • Hao, X.1    Chen, J.2    Luo, Z.3    He, H.4    Yu, H.5    Ma, L.6    Ma, S.7    Zhu, T.8    Liu, D.9    Zhu, Z.10
  • 52
    • 84904505279 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1 activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel alpha subunit-mediated sodium reabsorption
    • [CrossRef] [PubMed]
    • Li, L.; Wang, F.; Wei, X.; Liang, Y.; Cui, Y.; Gao, F.; Zhong, J.; Pu, Y.; Zhao, Y.; Yan, Z.; et al. Transient receptor potential vanilloid 1 activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel alpha subunit-mediated sodium reabsorption. Hypertension 2014, 64, 397-404. [CrossRef] [PubMed]
    • (2014) Hypertension , vol.64 , pp. 397-404
    • Li, L.1    Wang, F.2    Wei, X.3    Liang, Y.4    Cui, Y.5    Gao, F.6    Zhong, J.7    Pu, Y.8    Zhao, Y.9    Yan, Z.10
  • 53
    • 33751006744 scopus 로고    scopus 로고
    • Detection of nacl and kcl in TRPV1 knockout mice
    • [CrossRef] [PubMed]
    • Ruiz, C.; Gutknecht, S.; Delay, E.; Kinnamon, S. Detection of nacl and kcl in TRPV1 knockout mice. Chem. Senses 2006, 31, 813-820. [CrossRef] [PubMed]
    • (2006) Chem. Senses , vol.31 , pp. 813-820
    • Ruiz, C.1    Gutknecht, S.2    Delay, E.3    Kinnamon, S.4
  • 55
    • 34948836382 scopus 로고    scopus 로고
    • Hypolipidemic and antioxidant effects of curcumin and capsaicin in high-fat-fed rats
    • [CrossRef] [PubMed]
    • Manjunatha, H.; Srinivasan, K. Hypolipidemic and antioxidant effects of curcumin and capsaicin in high-fat-fed rats. Can. J. Physiol. Pharmacol. 2007, 85, 588-596. [CrossRef] [PubMed]
    • (2007) Can. J. Physiol. Pharmacol , vol.85 , pp. 588-596
    • Manjunatha, H.1    Srinivasan, K.2
  • 56
  • 57
    • 81055133078 scopus 로고    scopus 로고
    • Activation of TRPV1 reduces vascular lipid accumulation and attenuates atherosclerosis
    • [CrossRef] [PubMed]
    • Ma, L.; Zhong, J.; Zhao, Z.; Luo, Z.; Ma, S.; Sun, J.; He, H.; Zhu, T.; Liu, D.; Zhu, Z.; et al. Activation of TRPV1 reduces vascular lipid accumulation and attenuates atherosclerosis. Cardiovasc. Res. 2011, 92, 504-513. [CrossRef] [PubMed]
    • (2011) Cardiovasc. Res , vol.92 , pp. 504-513
    • Ma, L.1    Zhong, J.2    Zhao, Z.3    Luo, Z.4    Ma, S.5    Sun, J.6    He, H.7    Zhu, T.8    Liu, D.9    Zhu, Z.10
  • 58
    • 84880148488 scopus 로고    scopus 로고
    • Activation of TRPV1 prevents oxldl-induced lipid accumulation and tnf-alpha-induced inflammation in macrophages: Role of liver x receptor alpha
    • Zhao, J.F.; Ching, L.C.; Kou, Y.R.; Lin, S.J.; Wei, J.; Shyue, S.K.; Lee, T.S. Activation of TRPV1 prevents oxldl-induced lipid accumulation and tnf-alpha-induced inflammation in macrophages: Role of liver x receptor alpha. Mediat. Inflamm. 2013, 2013, 925171.
    • (2013) Mediat. Inflamm , vol.2013
    • Zhao, J.F.1    Ching, L.C.2    Kou, Y.R.3    Lin, S.J.4    Wei, J.5    Shyue, S.K.6    Lee, T.S.7
  • 59
    • 84954350476 scopus 로고    scopus 로고
    • Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase a/uncoupling protein 2 pathway
    • [CrossRef] [PubMed]
    • Xiong, S.; Wang, P.; Ma, L.; Gao, P.; Gong, L.; Li, L.; Li, Q.; Sun, F.; Zhou, X.; He, H.; et al. Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase a/uncoupling protein 2 pathway. Hypertension 2016, 67, 451-460. [CrossRef] [PubMed]
    • (2016) Hypertension , vol.67 , pp. 451-460
    • Xiong, S.1    Wang, P.2    Ma, L.3    Gao, P.4    Gong, L.5    Li, L.6    Li, Q.7    Sun, F.8    Zhou, X.9    He, H.10
  • 60
    • 84935001820 scopus 로고    scopus 로고
    • TRPV1 activation attenuates high-salt diet-induced cardiac hypertrophy and fibrosis through ppar-δ upregulation
    • Feng, G.; Yi, L.; Xiang, W.; Lu, Z.; Li, L.; Zhu, S.; Liu, D.; Yan, Z.; Zhu, Z. TRPV1 activation attenuates high-salt diet-induced cardiac hypertrophy and fibrosis through ppar-δ upregulation. PPAR Res. 2014, 2014, 491963.
    • (2014) PPAR Res , vol.2014
    • Feng, G.1    Yi, L.2    Xiang, W.3    Lu, Z.4    Li, L.5    Zhu, S.6    Liu, D.7    Yan, Z.8    Zhu, Z.9
  • 61
    • 84949534029 scopus 로고    scopus 로고
    • Activation of TRPV1 attenuates high salt induced cardiac hypertrophy through improvement of mitochondrial function
    • Hongmei, L.; Qiang, L.; Hao, Y.; Peng, L.; Lu, Z.; Xiong, S.; Tao, Y.; Yu, Z.; Huang, X.; Peng, G. Activation of TRPV1 attenuates high salt induced cardiac hypertrophy through improvement of mitochondrial function. Br. J. Pharmacol. 2014, 172, 5548-5558.
    • (2014) Br. J. Pharmacol , vol.172 , pp. 5548-5558
    • Hongmei, L.1    Qiang, L.2    Hao, Y.3    Peng, L.4    Lu, Z.5    Xiong, S.6    Tao, Y.7    Yu, Z.8    Huang, X.9    Peng, G.10
  • 62
    • 84925684948 scopus 로고    scopus 로고
    • Dietary capsaicin ameliorates pressure overload-induced cardiac hypertrophy and fibrosis through the transient receptor potential vanilloid type 1
    • Qiang, W.; Shuangtao, M.; De, L.; Yan, Z.; Bing, T.; Chenming, Q.; Yongjian, Y.; Dachun, Y. Dietary capsaicin ameliorates pressure overload-induced cardiac hypertrophy and fibrosis through the transient receptor potential vanilloid type 1. Am. J. Hypertens. 2014, 27, 1521-1529.
    • (2014) Am. J. Hypertens , vol.27 , pp. 1521-1529
    • Qiang, W.1    Shuangtao, M.2    De, L.3    Yan, Z.4    Bing, T.5    Chenming, Q.6    Yongjian, Y.7    Dachun, Y.8
  • 63
    • 80054968152 scopus 로고    scopus 로고
    • Activation of transient receptor potential vanilloid 1 by dietary capsaicin delays the onset of stroke in stroke-prone spontaneously hypertensive rats
    • [CrossRef] [PubMed]
    • Xu, X.; Wang, P.; Zhao, Z.; Cao, T.; He, H.; Luo, Z.; Zhong, J.; Gao, F.; Zhu, Z.; Li, L.; et al. Activation of transient receptor potential vanilloid 1 by dietary capsaicin delays the onset of stroke in stroke-prone spontaneously hypertensive rats. Stroke 2011, 42, 3245-3251. [CrossRef] [PubMed]
    • (2011) Stroke , vol.42 , pp. 3245-3251
    • Xu, X.1    Wang, P.2    Zhao, Z.3    Cao, T.4    He, H.5    Luo, Z.6    Zhong, J.7    Gao, F.8    Zhu, Z.9    Li, L.10
  • 65
    • 84876726039 scopus 로고    scopus 로고
    • TRPV1-mediated ucp2 upregulation ameliorates hyperglycemia-induced endothelial dysfunction
    • [CrossRef] [PubMed]
    • Sun, J.; Pu, Y.; Wang, P.; Chen, S.; Zhao, Y.; Liu, C.; Shang, Q.; Zhu, Z.; Liu, D. TRPV1-mediated ucp2 upregulation ameliorates hyperglycemia-induced endothelial dysfunction. Cardiovasc. Diabetol. 2013, 12, 69. [CrossRef] [PubMed]
    • (2013) Cardiovasc. Diabetol , vol.12 , pp. 69
    • Sun, J.1    Pu, Y.2    Wang, P.3    Chen, S.4    Zhao, Y.5    Liu, C.6    Shang, Q.7    Zhu, Z.8    Liu, D.9
  • 66
    • 84942833598 scopus 로고    scopus 로고
    • Impaired capsaicin-induced relaxation in diabetic mesenteric arteries
    • [CrossRef] [PubMed]
    • Zhang, Y.; Chen, Q.; Sun, Z.; Han, J.;Wang, L.; Zheng, L. Impaired capsaicin-induced relaxation in diabetic mesenteric arteries. J. Diabetes Complicat. 2015, 29, 747-754. [CrossRef] [PubMed]
    • (2015) J. Diabetes Complicat , vol.29 , pp. 747-754
    • Zhang, Y.1    Chen, Q.2    Sun, Z.3    Han, J.4    Wang, L.5    Zheng, L.6
  • 67
    • 84874588315 scopus 로고    scopus 로고
    • Molecular mechanisms of appetite regulation
    • [CrossRef] [PubMed]
    • Yu, J.H.; Kim, M.S. Molecular mechanisms of appetite regulation. Diabetes Metab. J. 2012, 36, 391-398. [CrossRef] [PubMed]
    • (2012) Diabetes Metab. J , vol.36 , pp. 391-398
    • Yu, J.H.1    Kim, M.S.2
  • 68
    • 84873827677 scopus 로고    scopus 로고
    • Gut hormones and obesity: Physiology and therapies
    • [PubMed]
    • Scott, R.; Tan, T.; Bloom, S. Gut hormones and obesity: Physiology and therapies. Vitam. Horm. 2013, 91, 143-194. [PubMed]
    • (2013) Vitam. Horm , vol.91 , pp. 143-194
    • Scott, R.1    Tan, T.2    Bloom, S.3
  • 69
    • 84866272024 scopus 로고    scopus 로고
    • Evaluation of insulin expression and secretion in genetically engineered gut k and l-cells
    • [CrossRef] [PubMed]
    • Ahmad, Z.; Rasouli, M.; Azman, A.Z.; Omar, A.R. Evaluation of insulin expression and secretion in genetically engineered gut k and l-cells. BMC Biotechnol. 2012, 12, 64. [CrossRef] [PubMed]
    • (2012) BMC Biotechnol , vol.12 , pp. 64
    • Ahmad, Z.1    Rasouli, M.2    Azman, A.Z.3    Omar, A.R.4
  • 70
    • 77951207195 scopus 로고    scopus 로고
    • Obesity: Genes, brain, gut, and environment
    • [CrossRef] [PubMed]
    • Das, U.N. Obesity: Genes, brain, gut, and environment. Nutrition 2010, 26, 459-473. [CrossRef] [PubMed]
    • (2010) Nutrition , vol.26 , pp. 459-473
    • Das, U.N.1
  • 71
    • 45449110183 scopus 로고    scopus 로고
    • Capsaicin-sensitive intestinal mucosal afferent mechanism and body fat distribution
    • [CrossRef] [PubMed]
    • Leung, F.W. Capsaicin-sensitive intestinal mucosal afferent mechanism and body fat distribution. Life Sci. 2008, 83, 1-5. [CrossRef] [PubMed]
    • (2008) Life Sci , vol.83 , pp. 1-5
    • Leung, F.W.1
  • 73
    • 67650888938 scopus 로고    scopus 로고
    • The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety
    • [CrossRef] [PubMed]
    • Smeets, A.J.; Westerterp-Plantenga, M.S. The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety. Eur. J. Nutr. 2009, 48, 229-234. [CrossRef] [PubMed]
    • (2009) Eur. J. Nutr , vol.48 , pp. 229-234
    • Smeets, A.J.1    Westerterp-Plantenga, M.S.2
  • 74
    • 77949310042 scopus 로고    scopus 로고
    • Ghrelin stimulates gastric motility of the guinea pig through activation of a capsaicin-sensitive neural pathway: In vivo and in vitro functional studies
    • [CrossRef] [PubMed]
    • Nakamura, T.; Onaga, T.; Kitazawa, T. Ghrelin stimulates gastric motility of the guinea pig through activation of a capsaicin-sensitive neural pathway: In vivo and in vitro functional studies. Neurogastroenterol. Motil. 2010, 4, 446-452. [CrossRef] [PubMed]
    • (2010) Neurogastroenterol. Motil , vol.4 , pp. 446-452
    • Nakamura, T.1    Onaga, T.2    Kitazawa, T.3
  • 75
    • 84883616379 scopus 로고    scopus 로고
    • New satiety hormone nesfatin-1 protects gastric mucosa against stress-induced injury: Mechanistic roles of prostaglandins, nitric oxide, sensory nerves and vanilloid receptors
    • [CrossRef] [PubMed]
    • Szlachcic, A.; Sliwowski, Z.; Krzysiek-Maczka, G.; Majka, J.; Surmiak, M.; Pajdo, R.; Drozdowicz, D.; Konturek, S.J.; Brzozowski, T. New satiety hormone nesfatin-1 protects gastric mucosa against stress-induced injury: Mechanistic roles of prostaglandins, nitric oxide, sensory nerves and vanilloid receptors. Peptides 2013, 49, 9-20. [CrossRef] [PubMed]
    • (2013) Peptides , vol.49 , pp. 9-20
    • Szlachcic, A.1    Sliwowski, Z.2    Krzysiek-Maczka, G.3    Majka, J.4    Surmiak, M.5    Pajdo, R.6    Drozdowicz, D.7    Konturek, S.J.8    Brzozowski, T.9
  • 76
    • 84942354100 scopus 로고    scopus 로고
    • Consumption of spicy foods and total and cause specific mortality: Population based cohort study
    • [CrossRef] [PubMed]
    • Lv, J.; Qi, L.; Yu, C.; Yang, L.; Guo, Y.; Chen, Y.; Bian, Z.; Sun, D.; Du, J.; Ge, P.; et al. Consumption of spicy foods and total and cause specific mortality: Population based cohort study. BMJ 2015, 351, h3942. [CrossRef] [PubMed]
    • (2015) BMJ , vol.351
    • Lv, J.1    Qi, L.2    Yu, C.3    Yang, L.4    Guo, Y.5    Chen, Y.6    Bian, Z.7    Sun, D.8    Du, J.9    Ge, P.10
  • 78
    • 84902573715 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid type-1 channel in cardiometabolic protection
    • [CrossRef]
    • Wang, P.; Liu, D.; Zhu, Z. Transient receptor potential vanilloid type-1 channel in cardiometabolic protection. J. Korean Soc. Hypertens. 2011, 37-47. [CrossRef]
    • (2011) J. Korean Soc. Hypertens , pp. 37-47
    • Wang, P.1    Liu, D.2    Zhu, Z.3
  • 80
    • 0032464789 scopus 로고    scopus 로고
    • Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women
    • [PubMed]
    • Yoshioka, M.; St-Pierre, S.; Suzuki, M.; Tremblay, A. Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women. Br. J. Nutr. 1998, 80, 503-510. [PubMed]
    • (1998) Br. J. Nutr , vol.80 , pp. 503-510
    • Yoshioka, M.1    St-Pierre, S.2    Suzuki, M.3    Tremblay, A.4
  • 81
    • 33847189521 scopus 로고    scopus 로고
    • Enhanced energy expenditure and fat oxidation in humans with high bmi scores by the ingestion of novel and non-pungent capsaicin analogues (capsinoids)
    • [CrossRef] [PubMed]
    • Inoue, N.; Satoh, Y.M. Enhanced energy expenditure and fat oxidation in humans with high bmi scores by the ingestion of novel and non-pungent capsaicin analogues (capsinoids). Biosci. Biotechnol. Biochem. 2007, 71, 380-389. [CrossRef] [PubMed]
    • (2007) Biosci. Biotechnol. Biochem , vol.71 , pp. 380-389
    • Inoue, N.1    Satoh, Y.M.2
  • 82
    • 84855904085 scopus 로고    scopus 로고
    • The effects of capsaicin and capsiate on energy balance: Critical review and meta-analyses of studies in humans
    • [CrossRef] [PubMed]
    • Ludy, M.J.; Moore, G.E.; Mattes, R.D. The effects of capsaicin and capsiate on energy balance: Critical review and meta-analyses of studies in humans. Chem. Senses 2012, 37, 103-121. [CrossRef] [PubMed]
    • (2012) Chem. Senses , vol.37 , pp. 103-121
    • Ludy, M.J.1    Moore, G.E.2    Mattes, R.D.3
  • 83
    • 33644888781 scopus 로고    scopus 로고
    • Capsaicin and glucose absorption and utilization in healthy human subjects
    • [CrossRef] [PubMed]
    • Dömötör, A.; Szolcsányi, J.; Mózsik, G. Capsaicin and glucose absorption and utilization in healthy human subjects. Eur. J. Pharmacol. 2006, 534, 280-283. [CrossRef] [PubMed]
    • (2006) Eur. J. Pharmacol , vol.534 , pp. 280-283
    • Dömötör, A.1    Szolcsányi, J.2    Mózsik, G.3
  • 84
    • 84931354816 scopus 로고    scopus 로고
    • A randomized clinical trial of efficacy and safety of the topical clonidine and capsaicin in the treatment of painful diabetic neuropathy
    • [PubMed]
    • Kiani, J.; Sajedi, F.; Nasrollahi, S.A.; Esna-Ashari, F. A randomized clinical trial of efficacy and safety of the topical clonidine and capsaicin in the treatment of painful diabetic neuropathy. J. Res. Med. Sci. 2015, 20, 359-363. [PubMed]
    • (2015) J. Res. Med. Sci , vol.20 , pp. 359-363
    • Kiani, J.1    Sajedi, F.2    Nasrollahi, S.A.3    Esna-Ashari, F.4
  • 85
    • 84905098167 scopus 로고    scopus 로고
    • Vanilloid-like agents inhibit aggregation of human platelets
    • [CrossRef] [PubMed]
    • Almaghrabi, S.Y.; Geraghty, D.P.; Ahuja, K.D.; Adams, M.J. Vanilloid-like agents inhibit aggregation of human platelets. Thromb. Res. 2014, 134, 412-417. [CrossRef] [PubMed]
    • (2014) Thromb. Res , vol.134 , pp. 412-417
    • Almaghrabi, S.Y.1    Geraghty, D.P.2    Ahuja, K.D.3    Adams, M.J.4
  • 88
    • 67949089783 scopus 로고    scopus 로고
    • Effects of capsaicin and isoflavone on blood pressure and serumlevels of insulin-like growth factor-i in normotensive and hypertensive volunteers with alopecia
    • [CrossRef] [PubMed]
    • Harada, N.; Okajima, K. Effects of capsaicin and isoflavone on blood pressure and serumlevels of insulin-like growth factor-i in normotensive and hypertensive volunteers with alopecia. Biosci. Biotechnol. Biochem. 2009, 73, 1456-1459. [CrossRef] [PubMed]
    • (2009) Biosci. Biotechnol. Biochem , vol.73 , pp. 1456-1459
    • Harada, N.1    Okajima, K.2
  • 89
    • 77249166565 scopus 로고    scopus 로고
    • Assessment of the biological similarity of three capsaicin analogs (capsinoids) found in non-pungent chili pepper (ch-19 sweet) fruits
    • Ikuko, S.; Yasufumi, F.; Yusaku, I.; Naohiko, I.; Hitoshi, S.; Tatsuo,W.; Michio, T. Assessment of the biological similarity of three capsaicin analogs (capsinoids) found in non-pungent chili pepper (ch-19 sweet) fruits. Biosci. Biotechnol. Biochem. 2010, 74, 274-278.
    • (2010) Biosci. Biotechnol. Biochem , vol.74 , pp. 274-278
    • Ikuko, S.1    Yasufumi, F.2    Yusaku, I.3    Naohiko, I.4    Hitoshi, S.5    Tatsuo, W.6    Michio, T.7


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