In vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of red pepper (Capsicum Annuum L.) including pericarp, placenta, and stalk

Journal of Food Biochemistry

Volumn 38, Issue 3, 2014, Pages 300-306

  Chen, Lei ^a   Kang, Young Hwa ^a  

^a Kyungpook National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AGRICULTURAL WASTES; AMYLASES; ENZYME INHIBITION; GLUCOSE;

1 ,1-DIPHENYL-2-PICRYLHYDRAZYL; ANGIOTENSIN I-CONVERTING ENZYME; ANTI-OXIDANT ACTIVITIES; CLINICAL APPLICATION; INHIBITORY ACTIVITY; INHIBITORY EFFECT; INHIBITORY PROFILES; THERAPEUTIC AGENTS;

PLANTS (BOTANY);

EID: 84901781370     PISSN: 01458884     EISSN: 17454514     Source Type: Journal    
DOI: 10.1111/jfbc.12048     Document Type: Article

References (29)

1. Ali, H., Houghton, P.J. and Soumyanath, A. 2006. α-Amylase inhibitory activity of some Malaysian plants used to treat diabetes with particular reference to Phyllanthusamarus. J. Ethnopharmacol. 107, 449-455.
2. Ani, V. and Naidu, A. 2008. Antihyperglycemic activity of polyphenolic components of black/bitter cumin Centratherum anthelminticum (L.) Kuntze seeds. Eur. Food Res. Technol. 226, 897-903.
3. Atkinson, A.B. and Robertson, J.I. 1979. Captopril in the treatment of clinical of hypertension and cardiac failure. Lancet 2, 836-839.
4. Chen, L., Hwang, J.E., Gu, K.M., Kim, J.H., Choi, B., Song, K.S., Park, Y. and Kang, Y.H. 2012. Comparative study of antioxidant effects of five Korean varieties red pepper (Capsicum annuum L) extracts from various parts including placenta, stalk, and pericarp. Food Sci. Biotechnol. 21, 715-721.
5. Chiasson, J.L., Josse, R.G. and Gomis, R. 2002. Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomized trial. Lancet 359, 2072-2077.
6. Choi, H.S., Choc, H.Y., Yangc, H.C., Rad, K.S. and Suha, H.J. 2001. Angiotensin I-converting enzyme inhibitor from Grifola frondos. Food Res. Inter. 34, 177-182.
7. Cieslik, E., Greda, A. and Adamus, W. 2006. Contents of polyphenol in fruits and vegetables. Food Chem. 94, 135-142.
8. Eichler, H.G., Korn, A., Gasic, S., Pirson, W. and Businger, J. 1984. The effect of a new specific a-amylase inhibitor on post-prandial glucose and insulin excursions in normal subjects and type 2 (non-insulin-dependent) diabetic patients. Diabetologia 26, 278-281.
9. Erdos, E.G. and Skidgel, R.A. 1987. The angiotensin I-converting enzyme. Lab. Invest. 56, 345-348.
10. Fernando, M.R., Wickramasinghe, N., Thabrew, M.I., Ariyananda, P.L. and Karunanayake, E.H. 1991. Effect of Artocarpus heterophyllus and Asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients. J. Ethnopharmacol. 31, 277-282.
11. Howard, L.R., Talcott, S.T., Brenes, C.H. and Villalon, B. 2000. Changes in phytochemical and antioxidant activity of selected pepper cultivars (Capsicum species) as influenced by maturity. J. Agric. Food Chem. 48, 1713-1720.
12. Huynh, H.T. and Teel, R.W. 2005. In Vitro antimutagenicity of capsaicin toward heterocyclic amines in Salmonella Typhimurium strain TA98. Anticancer Res. 25, 117-120.
13. Koike, D., Yamadera, K. and Dimagno, E.P. 1995. Effect of a wheat amylase inhibitor on canine carbohydrate digestion, gastrointestinal function, and pancreatic growth. Gastroenterology 108, 1221-1229.
14. Koo, H.M. and Mohamed, S. 2001. Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J. Agric. Food Chem. 49, 3106-3112.
15. Kris-Etherton, P., Hecker, K., Bonanome, A., Coval, S., Binkoski, A. and Hilpert, K. 2002. Bioactive compounds in foods: Their role in the prevention of cardiovascular disease and cancer. Am. J. Med. 113, 71-88.
16. Kwon, Y.I., Apostolidis, E. and Shetty, K. 2007. Evaluation of pepper (Capsicum annuum) for management of diabetes and hypertension. J. Food Biochem. 31, 370-385.
17. Kwon, Y.I., Vattem, D.V. and Shetty, K. 2006. Evaluation of clonal herb of Lamiaceae species for management of diabetes and hypertension. Asia Pac. J. Clin. Nutr. 15, 107-118.
18. Laviada, I. 2006. Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin. Apoptosis 11, 89-99.
19. Lee, Y.U., Huang, G.W., Liang, Z.C. and Mau, J.L. 2007. Antioxidant properties of three extract from Pleurotus citrinopileatus. LWT-Food Sci. Technol. 40, 823-833.
20. Marin, A., Ferreres, F., Tomas-Barberaan, F.A. and Gil, M.I. 2004. Characterization and quantitation of antioxidant constituents of sweet pepper (Capsicum annuum L.). J. Agric. Food Chem. 52, 3861-3869.
21. Oh, G.S., Pae, H.O., Seo, W.G., Kim, N.Y., Pyun, K.H., Kim, I.K., Shin, M.K. and Chung, H.T. 2001. Capsazepine, a vanilloid receptor antagonist, inhibits the expression of inducible nitric oxide synthase gene in lipopolysaccharide-stimulated RAW264.7 macrophages through the inactivation of nuclear transcription factor-kappa B. Int. Immunopharmacol. 1, 777-784.
22. Olga, C.P., Luis, W.T., Carlos, G., Fernando, C.M., Tomas, G.E. and Sergio, R.P. 2007. Capsaicinoids quantification in chili peppers cultivated in the state of Yucatan, Mexico. Food Chem. 104, 1755-1760.
23. Prior, R.L., Wu, X. and Shaich, K. 2005. Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements. J. Agric. Food Chem. 53, 4290-4302.
24. Ranilla, L.G., Kwon, Y.I., Apostolidis, A. and Shetty, K. 2010. Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America. Bioresour. Technol. 101, 4676-4689.
25. Scalbert, A., Manach, C., Morand, C. and Remesy, C. 2005. Dietary polyphenol and the prevention of diseases. Crit. Rev. Food Sci. Nutr. 45, 287-306.
26. Sim, K.Y. and Sil, H.Y. 2008. Antioxidant activities of red pepper (Capsicum annuum) pericarp and seed extracts. Int. J. Food Sci. Tech. 43, 1813-1823.
27. Suresh, B.P. and Srinivasan, K. 1998. Amelioration of renal lesions associated with diabetes by dietary curcumin in streptootocin diabetic rats. Mol. Cell. Biochem. 181, 87-96.
28. Ukeda, H., Matsuda, H., Kuroda, H., Osajima, K., Matsufuj, H. and Osajima, Y. 1991. Preparation of angiotensin I converting enzyme inhibitory peptides. Nippon Nogek. Kaishi 65, 1223-1228.
29. +-dependent d-glucose uptake in rat intestinal brush border membrane vesicles. J. Nutr. 119, 1698-1704.