-
1
-
-
82255186724
-
Predicting phenotypic variation in yeast from individual genome sequences
-
Jelier R, Semple JI, Garcia-Verdugo R, Lehner B: Predicting phenotypic variation in yeast from individual genome sequences. Nat Genet 2011, 43:1270-1274.
-
(2011)
Nat Genet
, vol.43
, pp. 1270-1274
-
-
Jelier, R.1
Semple, J.I.2
Garcia-Verdugo, R.3
Lehner, B.4
-
2
-
-
84925031191
-
Methods of integrating data to uncover genotype-phenotype interactions
-
Ritchie MD, Holzinger ER, Li R, Pendergrass SA, Kim D: Methods of integrating data to uncover genotype-phenotype interactions. Nat Rev Genet 2015, 16:85-97.
-
(2015)
Nat Rev Genet
, vol.16
, pp. 85-97
-
-
Ritchie, M.D.1
Holzinger, E.R.2
Li, R.3
Pendergrass, S.A.4
Kim, D.5
-
3
-
-
84901686870
-
An atlas of genetic influences on human blood metabolites
-
Shin S-Y, Fauman EB, Petersen A-K, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang T-P, et al.: An atlas of genetic influences on human blood metabolites. Nat Genet 2014, 46:543-550.
-
(2014)
Nat Genet
, vol.46
, pp. 543-550
-
-
Shin, S-Y.1
Fauman, E.B.2
Petersen, A-K.3
Krumsiek, J.4
Santos, R.5
Huang, J.6
Arnold, M.7
Erte, I.8
Forgetta, V.9
Yang, T-P.10
-
4
-
-
84961308786
-
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease
-
Hartiala JA, Wilson Tang WH, Wang Z, Crow AL, Stewart AFR, Roberts R, McPherson R, Erdmann J, Willenborg C, Hazen SL, et al.: Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease. Nat Commun 2016, 7:10558.
-
(2016)
Nat Commun
, vol.7
, pp. 10558
-
-
Hartiala, J.A.1
Wilson Tang, W.H.2
Wang, Z.3
Crow, A.L.4
Stewart, A.F.R.5
Roberts, R.6
McPherson, R.7
Erdmann, J.8
Willenborg, C.9
Hazen, S.L.10
-
5
-
-
84877315835
-
A community-driven global reconstruction of human metabolism
-
Thiele I, Swainston N, Fleming RMT, Hoppe A, Sahoo S, Aurich MK, Haraldsdottir H, Mo ML, Rolfsson O, Stobbe MD, et al.: A community-driven global reconstruction of human metabolism. Nat Biotechnol 2013, 31:419-425.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 419-425
-
-
Thiele, I.1
Swainston, N.2
Fleming, R.M.T.3
Hoppe, A.4
Sahoo, S.5
Aurich, M.K.6
Haraldsdottir, H.7
Mo, M.L.8
Rolfsson, O.9
Stobbe, M.D.10
-
6
-
-
85006746732
-
Integrating GWAS and Coexpression network data identifies bone mineral density genes SPTBN1 and MARK3 and an osteoblast functional module
-
Calabrese GM, Mesner LD, Stains JP, Tommasini SM, Horowitz MC, Rosen CJ, Farber CR: Integrating GWAS and Coexpression network data identifies bone mineral density genes SPTBN1 and MARK3 and an osteoblast functional module. Cell Syst 2017, 4:.46-59.e4.
-
(2017)
Cell Syst
, vol.4
, pp. 46-59
-
-
Calabrese, G.M.1
Mesner, L.D.2
Stains, J.P.3
Tommasini, S.M.4
Horowitz, M.C.5
Rosen, C.J.6
Farber, C.R.7
-
7
-
-
84915815121
-
Identification of causal genetic drivers of human disease through systemslevel analysis of regulatory networks
-
Chen JC, Alvarez MJ, Talos F, Dhruv H, Rieckhof GE, Iyer A, Diefes KL, Aldape K, Berens M, Shen MM, et al.: Identification of causal genetic drivers of human disease through systemslevel analysis of regulatory networks. Cell 2014, 159:402-414.
-
(2014)
Cell
, vol.159
, pp. 402-414
-
-
Chen, J.C.1
Alvarez, M.J.2
Talos, F.3
Dhruv, H.4
Rieckhof, G.E.5
Iyer, A.6
Diefes, K.L.7
Aldape, K.8
Berens, M.9
Shen, M.M.10
-
8
-
-
85016161935
-
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
-
MacArthur J, Bowler E, Cerezo M, Gil L, Hall P, Hastings E, Junkins H, McMahon A, Milano A, Morales J, et al.: The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). Nucleic Acids Res 2017, 45: D896-D901.
-
(2017)
Nucleic Acids Res
, vol.45
, pp. D896-D901
-
-
MacArthur, J.1
Bowler, E.2
Cerezo, M.3
Gil, L.4
Hall, P.5
Hastings, E.6
Junkins, H.7
McMahon, A.8
Milano, A.9
Morales, J.10
-
9
-
-
84984871169
-
Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster
-
Okada H, Ebhardt HA, Vonesch SC, Aebersold R, Hafen E: Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster. Nat Commun 2016, 7. ncomms12649.
-
(2016)
Nat Commun
, vol.7
, pp. 12649
-
-
Okada, H.1
Ebhardt, H.A.2
Vonesch, S.C.3
Aebersold, R.4
Hafen, E.5
-
10
-
-
84940780615
-
A gene-based association method for mapping traits using reference transcriptome data
-
Gamazon ER, Wheeler HE, Shah KP, Mozaffari SV, Aquino- Michaels K, Carroll RJ, Eyler AE, Denny JC, GTEx Consortium, Nicolae DL, et al.: A gene-based association method for mapping traits using reference transcriptome data. Nat Genet 2015, 47:1091-1098.
-
(2015)
Nat Genet
, vol.47
, pp. 1091-1098
-
-
Gamazon, E.R.1
Wheeler, H.E.2
Shah, K.P.3
Mozaffari, S.V.4
Aquino-Michaels, K.5
Carroll, R.J.6
Eyler, A.E.7
Denny, J.C.8
Nicolae, D.L.9
-
11
-
-
84923645756
-
Quantitative variability of 342 plasma proteins in a human twin population
-
Liu Y, Buil A, Collins BC, Gillet LCJ, Blum LC, Cheng L-Y, Vitek O, Mouritsen J, Lachance G, Spector TD, et al.: Quantitative variability of 342 plasma proteins in a human twin population. Mol Syst Biol 2015, 11:786.
-
(2015)
Mol Syst Biol
, vol.11
, pp. 786
-
-
Liu, Y.1
Buil, A.2
Collins, B.C.3
Gillet, L.C.J.4
Blum, L.C.5
Cheng, L-Y.6
Vitek, O.7
Mouritsen, J.8
Lachance, G.9
Spector, T.D.10
-
12
-
-
79953737332
-
Metabolite profiles and the risk of developing diabetes
-
Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, et al.: Metabolite profiles and the risk of developing diabetes. Nat Med 2011, 17: 448-453.
-
(2011)
Nat Med
, vol.17
, pp. 448-453
-
-
Wang, T.J.1
Larson, M.G.2
Vasan, R.S.3
Cheng, S.4
Rhee, E.P.5
McCabe, E.6
Lewis, G.D.7
Fox, C.S.8
Jacques, P.F.9
Fernandez, C.10
-
13
-
-
85014061753
-
Connecting genetic risk to disease end points through the human blood plasma proteome
-
Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, et al.: Connecting genetic risk to disease end points through the human blood plasma proteome. Nat Commun 2017, 8. ncomms14357.
-
(2017)
Nat Commun
, vol.8
, pp. 14357
-
-
Suhre, K.1
Arnold, M.2
Bhagwat, A.M.3
Cotton, R.J.4
Engelke, R.5
Raffler, J.6
Sarwath, H.7
Thareja, G.8
Wahl, A.9
DeLisle, R.K.10
-
14
-
-
84896507396
-
Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights
-
Wen W, Li D, Li X, Gao Y, Li W, Li H, Liu J, Liu H, Chen W, Luo J, et al.: Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights. Nat Commun 2014, 5. ncomms4438.
-
(2014)
Nat Commun
, vol.5
, pp. ncomms4438
-
-
Wen, W.1
Li, D.2
Li, X.3
Gao, Y.4
Li, W.5
Li, H.6
Liu, J.7
Liu, H.8
Chen, W.9
Luo, J.10
-
15
-
-
84962271039
-
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
-
Kettunen J, Demirkan A, Würtz P, Draisma HHM, Haller T, Rawal R, Vaarhorst A, Kangas AJ, Lyytikäinen L-P, Pirinen M, et al.: Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Nat Commun 2016, 7. ncomms11122.
-
(2016)
Nat Commun
, vol.7
, pp. 11122
-
-
Kettunen, J.1
Demirkan, A.2
Würtz, P.3
Draisma, H.H.M.4
Haller, T.5
Rawal, R.6
Vaarhorst, A.7
Kangas, A.J.8
Lyytikäinen, L-P.9
Pirinen, M.10
-
16
-
-
85014558361
-
Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites
-
Long T, Hicks M, Yu H-C, Biggs WH, Kirkness EF, Menni C, Zierer J, Small KS, Mangino M, Messier H, et al.: Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites. Nat Genet 2017, 49:568-578.
-
(2017)
Nat Genet
, vol.49
, pp. 568-578
-
-
Long, T.1
Hicks, M.2
Yu, H-C.3
Biggs, W.H.4
Kirkness, E.F.5
Menni, C.6
Zierer, J.7
Small, K.S.8
Mangino, M.9
Messier, H.10
-
17
-
-
75749134031
-
A genome-wide perspective of genetic variation in human metabolism
-
Illig T, Gieger C, Zhai G, Römisch-Margl W, Wang-Sattler R, Prehn C, Altmaier E, Kastenmüller G, Kato BS, Mewes H-W, et al.: A genome-wide perspective of genetic variation in human metabolism. Nat Genet 2010, 42:137-141.
-
(2010)
Nat Genet
, vol.42
, pp. 137-141
-
-
Illig, T.1
Gieger, C.2
Zhai, G.3
Römisch-Margl, W.4
Wang-Sattler, R.5
Prehn, C.6
Altmaier, E.7
Kastenmüller, G.8
Kato, B.S.9
Mewes, H-W.10
-
18
-
-
85010952930
-
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
-
Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, et al.: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet 2017, 49:403-415.
-
(2017)
Nat Genet
, vol.49
, pp. 403-415
-
-
Warren, H.R.1
Evangelou, E.2
Cabrera, C.P.3
Gao, H.4
Ren, M.5
Mifsud, B.6
Ntalla, I.7
Surendran, P.8
Liu, C.9
Cook, J.P.10
-
19
-
-
85008391609
-
Frontiers of highthroughput metabolomics
-
Zampieri M, Sekar K, Zamboni N, Sauer U: Frontiers of highthroughput metabolomics. Curr Opin Chem Biol 2017, 36: 15-23.
-
(2017)
Curr Opin Chem Biol
, vol.36
, pp. 15-23
-
-
Zampieri, M.1
Sekar, K.2
Zamboni, N.3
Sauer, U.4
-
20
-
-
85019408321
-
Integrating clinical metabolomics-based biomarker discovery and clinical pharmacology to enable precision medicine [Internet]
-
Kohler I, Hankemeier T, van der Graaf PH, Knibbe CAJ, van Hasselt JGC: Integrating clinical metabolomics-based biomarker discovery and clinical pharmacology to enable precision medicine [Internet] Eur J Pharm Sci 2017, http:// dx.doi.org/10.1016/j.ejps.2017.05.018.
-
(2017)
Eur J Pharm Sci
-
-
Kohler, I.1
Hankemeier, T.2
van der Graaf, P.H.3
Knibbe, C.A.J.4
van Hasselt, J.G.C.5
-
21
-
-
84963716209
-
Global urine metabolomics in patients treated with first-line tuberculosis drugs and identification of a novel metabolite of ethambutol
-
Das MK, Arya R, Debnath S, Debnath R, Lodh A, Bishwal SC, Das A, Nanda RK: Global urine metabolomics in patients treated with first-line tuberculosis drugs and identification of a novel metabolite of ethambutol. Antimicrob Agents Chemother 2016, 60:2257-2264.
-
(2016)
Antimicrob Agents Chemother
, vol.60
, pp. 2257-2264
-
-
Das, M.K.1
Arya, R.2
Debnath, S.3
Debnath, R.4
Lodh, A.5
Bishwal, S.C.6
Das, A.7
Nanda, R.K.8
-
22
-
-
84891694472
-
Metabolic rates of ATP transfer through creatine kinase (CK flux) predict clinical heart failure events and death
-
Bottomley PA, Panjrath GS, Lai S, Hirsch GA, Wu K, Najjar SS, Steinberg A, Gerstenblith G, Weiss RG: Metabolic rates of ATP transfer through creatine kinase (CK flux) predict clinical heart failure events and death. Sci Transl Med 2013, 5. 215re3.
-
(2013)
Sci Transl Med
, vol.5
, pp. 215re3
-
-
Bottomley, P.A.1
Panjrath, G.S.2
Lai, S.3
Hirsch, G.A.4
Wu, K.5
Najjar, S.S.6
Steinberg, A.7
Gerstenblith, G.8
Weiss, R.G.9
-
23
-
-
77956417789
-
Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism
-
Jerby L, Shlomi T, Ruppin E: Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism. Mol Syst Biol 2010, 6:401.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 401
-
-
Jerby, L.1
Shlomi, T.2
Ruppin, E.3
-
24
-
-
84951056186
-
Personalized whole-cell kinetic models of metabolism for discovery in genomics and pharmacodynamics
-
Bordbar A, McCloskey D, Zielinski DC, Sonnenschein N, Jamshidi N, Palsson BO: Personalized whole-cell kinetic models of metabolism for discovery in genomics and pharmacodynamics. Cell Syst 2015, 1:283-292.
-
(2015)
Cell Syst
, vol.1
, pp. 283-292
-
-
Bordbar, A.1
McCloskey, D.2
Zielinski, D.C.3
Sonnenschein, N.4
Jamshidi, N.5
Palsson, B.O.6
-
25
-
-
84930373777
-
Prediction of intracellular metabolic states from extracellular metabolomic data
-
Aurich MK, Paglia G, Rolfsson ó, Hrafnsdóttir S, Magnúsdóttir M, Stefaniak MM, Palsson BØ, Fleming RMT, Thiele I: Prediction of intracellular metabolic states from extracellular metabolomic data. Metabolomics 2015, 11:603-619.
-
(2015)
Metabolomics
, vol.11
, pp. 603-619
-
-
Aurich, M.K.1
Paglia, G.2
Rolfsson, O.3
Hrafnsdóttir, S.4
Magnúsdóttir, M.5
Stefaniak, M.M.6
Palsson, BØ.7
Fleming, R.M.T.8
Thiele, I.9
-
26
-
-
0018170113
-
Hyperphenylalaninemia due to a deficiency of biopterin A variant form of phenylketonuria
-
Kaufman S, Berlow S, Summer GK, Milstien S, Schulman JD, Orloff S, Spielberg S, Pueschel S: Hyperphenylalaninemia due to a deficiency of biopterin. A variant form of phenylketonuria. N Engl J Med 1978, 299:673-679.
-
(1978)
N Engl J Med
, vol.299
, pp. 673-679
-
-
Kaufman, S.1
Berlow, S.2
Summer, G.K.3
Milstien, S.4
Schulman, J.D.5
Orloff, S.6
Spielberg, S.7
Pueschel, S.8
-
27
-
-
84958749958
-
An integrated metabolic atlas of clear cell renal cell carcinoma
-
Hakimi AA, Reznik E, Lee C-H, Creighton CJ, Brannon AR, Luna A, Aksoy BA, Liu EM, Shen R, Lee W, et al.: An integrated metabolic atlas of clear cell renal cell carcinoma. Cancer Cell 2016, 29:104-116.
-
(2016)
Cancer Cell
, vol.29
, pp. 104-116
-
-
Hakimi, A.A.1
Reznik, E.2
Lee, C-H.3
Creighton, C.J.4
Brannon, A.R.5
Luna, A.6
Aksoy, B.A.7
Liu, E.M.8
Shen, R.9
Lee, W.10
-
28
-
-
84938094391
-
Characterizing metabolic changes in human colorectal cancer
-
Williams MD, Zhang X, Park J-J, Siems WF, Gang DR, Resar LMS, Reeves R, Hill HH: Characterizing metabolic changes in human colorectal cancer. Anal Bioanal Chem 2015, 407:4581-4595.
-
(2015)
Anal Bioanal Chem
, vol.407
, pp. 4581-4595
-
-
Williams, M.D.1
Zhang, X.2
Park, J-J.3
Siems, W.F.4
Gang, D.R.5
Resar, L.M.S.6
Reeves, R.7
Hill, H.H.8
-
29
-
-
84892939615
-
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
-
Terunuma A, Putluri N, Mishra P, Mathé EA, Dorsey TH, Yi M, Wallace TA, Issaq HJ, Zhou M, Killian JK, et al.: MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis. J Clin Invest 2014, 124:398-412.
-
(2014)
J Clin Invest
, vol.124
, pp. 398-412
-
-
Terunuma, A.1
Putluri, N.2
Mishra, P.3
Mathé, E.A.4
Dorsey, T.H.5
Yi, M.6
Wallace, T.A.7
Issaq, H.J.8
Zhou, M.9
Killian, J.K.10
-
30
-
-
84997404935
-
The metabolic background is a global player in Saccharomyces gene expression epistasis
-
Alam MT, Zelezniak A, Mülleder M, Shliaha P, Schwarz R, Capuano F, Vowinckel J, Radmaneshfar E, Krüger A, Calvani E, et al.: The metabolic background is a global player in Saccharomyces gene expression epistasis. Nat Microbiol 2016, 1:15030.
-
(2016)
Nat Microbiol
, vol.1
, pp. 15030
-
-
Alam, M.T.1
Zelezniak, A.2
Mülleder, M.3
Shliaha, P.4
Schwarz, R.5
Capuano, F.6
Vowinckel, J.7
Radmaneshfar, E.8
Krüger, A.9
Calvani, E.10
-
31
-
-
84999808819
-
The protein cost of metabolic fluxes: prediction from enzymatic rate laws and cost minimization
-
Noor E, Flamholz A, Bar-Even A, Davidi D, Milo R, Liebermeister W: The protein cost of metabolic fluxes: prediction from enzymatic rate laws and cost minimization. PLOS Comput Biol 2016, 12, e1005167.
-
(2016)
PLOS Comput Biol
, vol.12
-
-
Noor, E.1
Flamholz, A.2
Bar-Even, A.3
Davidi, D.4
Milo, R.5
Liebermeister, W.6
-
32
-
-
84931275672
-
Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis
-
Zielinski DC, Filipp FV, Bordbar A, Jensen K, Smith JW, Herrgard MJ, Mo ML, Palsson BO: Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis. Nat Commun 2015, 6: 7101.
-
(2015)
Nat Commun
, vol.6
, pp. 7101
-
-
Zielinski, D.C.1
Filipp, F.V.2
Bordbar, A.3
Jensen, K.4
Smith, J.W.5
Herrgard, M.J.6
Mo, M.L.7
Palsson, B.O.8
-
33
-
-
85017208176
-
Elucidating dynamic metabolic physiology through network integration of quantitative time-course metabolomics
-
Bordbar A, Yurkovich JT, Paglia G, Rolfsson O, Sigurjónsson óE, Palsson BO: Elucidating dynamic metabolic physiology through network integration of quantitative time-course metabolomics. Sci Rep 2017, 7:46249.
-
(2017)
Sci Rep
, vol.7
, pp. 46249
-
-
Bordbar, A.1
Yurkovich, J.T.2
Paglia, G.3
Rolfsson, O.4
Sigurjónsson, óE.5
Palsson, B.O.6
-
34
-
-
84978711445
-
Construction of feasible and accurate kinetic models of metabolism: a Bayesian approach
-
Saa PA, Nielsen LK: Construction of feasible and accurate kinetic models of metabolism: a Bayesian approach. Sci Rep 2016, 6. srep29635.
-
(2016)
Sci Rep
, vol.6
, pp. srep29635
-
-
Saa, P.A.1
Nielsen, L.K.2
-
35
-
-
85023208659
-
The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization
-
Alam MT, Olin-Sandoval V, Stincone A, Keller MA, Zelezniak A, Luisi BF, Ralser M: The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization. Nat Commun 2017, 8. ncomms16018.
-
(2017)
Nat Commun
, vol.8
, pp. 16018
-
-
Alam, M.T.1
Olin-Sandoval, V.2
Stincone, A.3
Keller, M.A.4
Zelezniak, A.5
Luisi, B.F.6
Ralser, M.7
-
36
-
-
1942436221
-
Mendelian randomization: prospects, potentials, and limitations
-
Smith GD, Ebrahim S: Mendelian randomization: prospects, potentials, and limitations. Int J Epidemiol 2004, 33:30-42.
-
(2004)
Int J Epidemiol
, vol.33
, pp. 30-42
-
-
Smith, G.D.1
Ebrahim, S.2
-
37
-
-
85017420204
-
Loss-of-function variants influence the human serum metabolome
-
Yu B, Li AH, Metcalf GA, Muzny DM, Morrison AC, White S, Mosley TH, Gibbs RA, Boerwinkle E: Loss-of-function variants influence the human serum metabolome. Sci Adv 2016, 2, e1600800.
-
(2016)
Sci Adv
, vol.2
-
-
Yu, B.1
Li, A.H.2
Metcalf, G.A.3
Muzny, D.M.4
Morrison, A.C.5
White, S.6
Mosley, T.H.7
Gibbs, R.A.8
Boerwinkle, E.9
-
38
-
-
84937560990
-
Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate
-
Menni C, Graham D, Kastenmüller G, Alharbi NHJ, Alsanosi SM, McBride M, Mangino M, Titcombe P, Shin S-Y, Psatha M, et al.: Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertens Dallas Tex 1979 2015, 66:422-429.
-
(2015)
Hypertens Dallas Tex 1979
, vol.66
, pp. 422-429
-
-
Menni, C.1
Graham, D.2
Kastenmüller, G.3
Alharbi, N.H.J.4
Alsanosi, S.M.5
McBride, M.6
Mangino, M.7
Titcombe, P.8
Shin, S-Y.9
Psatha, M.10
-
39
-
-
85029491871
-
Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis
-
Wang L, Ko ER, Gilchrist JJ, Pittman KJ, Rautanen A, Pirinen M, Thompson JW, Dubois LG, Langley RJ, Jaslow SL, et al.: Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis. Sci Adv 2017, 3, e1602096.
-
(2017)
Sci Adv
, vol.3
-
-
Wang, L.1
Ko, E.R.2
Gilchrist, J.J.3
Pittman, K.J.4
Rautanen, A.5
Pirinen, M.6
Thompson, J.W.7
Dubois, L.G.8
Langley, R.J.9
Jaslow, S.L.10
-
40
-
-
84867743261
-
Genome-wide association studies in mice
-
Flint J, Eskin E: Genome-wide association studies in mice. Nat Rev Genet 2012, 13:807-817.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 807-817
-
-
Flint, J.1
Eskin, E.2
-
41
-
-
84975156981
-
Systems proteomics of liver mitochondria function
-
Williams EG, Wu Y, Jha P, Dubuis S, Blattmann P, Argmann CA, Houten SM, Amariuta T, Wolski W, Zamboni N, et al.: Systems proteomics of liver mitochondria function. Science 2016, 352. aad0189.
-
(2016)
Science
, vol.352
, pp. aad0189
-
-
Williams, E.G.1
Wu, Y.2
Jha, P.3
Dubuis, S.4
Blattmann, P.5
Argmann, C.A.6
Houten, S.M.7
Amariuta, T.8
Wolski, W.9
Zamboni, N.10
-
42
-
-
79953094978
-
Network quantitative trait loci mapping of circadian clock outputs identifies metabolic pathway-to-clock linkages in Arabidopsis
-
Kerwin RE, Jimenez-Gomez JM, Fulop D, Harmer SL, Maloof JN, Kliebenstein DJ: Network quantitative trait loci mapping of circadian clock outputs identifies metabolic pathway-to-clock linkages in Arabidopsis. Plant Cell 2011, 23:471-485.
-
(2011)
Plant Cell
, vol.23
, pp. 471-485
-
-
Kerwin, R.E.1
Jimenez-Gomez, J.M.2
Fulop, D.3
Harmer, S.L.4
Maloof, J.N.5
Kliebenstein, D.J.6
-
43
-
-
84897455911
-
Genetic basis of metabolome variation in yeast
-
Breunig JS, Hackett SR, Rabinowitz JD, Kruglyak L: Genetic basis of metabolome variation in yeast. PLOS Genet 2014, 10, e1004142.
-
(2014)
PLOS Genet
, vol.10
-
-
Breunig, J.S.1
Hackett, S.R.2
Rabinowitz, J.D.3
Kruglyak, L.4
-
44
-
-
84901823390
-
Mapping an atlas of tissue-specific Drosophila melanogaster metabolomes by high resolution mass spectrometry
-
Chintapalli VR, Bratty MA, Korzekwa D, Watson DG, Dow JAT: Mapping an atlas of tissue-specific Drosophila melanogaster metabolomes by high resolution mass spectrometry. PLOS ONE 2013, 8, e78066.
-
(2013)
PLOS ONE
, vol.8
-
-
Chintapalli, V.R.1
Bratty, M.A.2
Korzekwa, D.3
Watson, D.G.4
Dow, J.A.T.5
-
45
-
-
84902440699
-
Systems genomics of metabolic phenotypes in wild-type Drosophila melanogaster
-
Reed LK, Lee K, Zhang Z, Rashid L, Poe A, Hsieh B, Deighton N, Glassbrook N, Bodmer R, Gibson G: Systems genomics of metabolic phenotypes in wild-type Drosophila melanogaster. Genetics 2014, http://dx.doi.org/10.1534/genetics.114.163857.
-
(2014)
Genetics
-
-
Reed, L.K.1
Lee, K.2
Zhang, Z.3
Rashid, L.4
Poe, A.5
Hsieh, B.6
Deighton, N.7
Glassbrook, N.8
Bodmer, R.9
Gibson, G.10
-
46
-
-
84914170959
-
Cold adaptation shapes the robustness of metabolic networks in Drosophila melanogaster
-
Williams CM, Watanabe M, Guarracino MR, Ferraro MB, Edison AS, Morgan TJ, Boroujerdi AFB, Hahn DA: Cold adaptation shapes the robustness of metabolic networks in Drosophila melanogaster. Evolution 2014, 68:3505-3523.
-
(2014)
Evolution
, vol.68
, pp. 3505-3523
-
-
Williams, C.M.1
Watanabe, M.2
Guarracino, M.R.3
Ferraro, M.B.4
Edison, A.S.5
Morgan, T.J.6
Boroujerdi, A.F.B.7
Hahn, D.A.8
-
47
-
-
84872156123
-
Genetic control of obesity and gut microbiota composition in response to highfat, high-sucrose diet in mice
-
Parks BW, Nam E, Org E, Kostem E, Norheim F, Hui ST, Pan C, Civelek M, Rau CD, Bennett BJ, et al.: Genetic control of obesity and gut microbiota composition in response to highfat, high-sucrose diet in mice. Cell Metab 2013, 17:141-152.
-
(2013)
Cell Metab
, vol.17
, pp. 141-152
-
-
Parks, B.W.1
Nam, E.2
Org, E.3
Kostem, E.4
Norheim, F.5
Hui, S.T.6
Pan, C.7
Civelek, M.8
Rau, C.D.9
Bennett, B.J.10
-
48
-
-
79952255290
-
Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism
-
Hatanaka F, Matsubara C, Myung J, Yoritaka T, Kamimura N, Tsutsumi S, Kanai A, Suzuki Y, Sassone-Corsi P, Aburatani H, et al.: Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism. Mol Cell Biol 2010, 30:5636-5648.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 5636-5648
-
-
Hatanaka, F.1
Matsubara, C.2
Myung, J.3
Yoritaka, T.4
Kamimura, N.5
Tsutsumi, S.6
Kanai, A.7
Suzuki, Y.8
Sassone-Corsi, P.9
Aburatani, H.10
-
49
-
-
84940830979
-
FTO obesity variant circuitry and adipocyte browning in humans
-
Claussnitzer M, Dankel SN, Kim K-H, Quon G, Meuleman W, Haugen C, Glunk V, Sousa IS, Beaudry JL, Puviindran V, et al.: FTO obesity variant circuitry and adipocyte browning in humans. N Engl J Med 2015, 373:895-907.
-
(2015)
N Engl J Med
, vol.373
, pp. 895-907
-
-
Claussnitzer, M.1
Dankel, S.N.2
Kim, K-H.3
Quon, G.4
Meuleman, W.5
Haugen, C.6
Glunk, V.7
Sousa, I.S.8
Beaudry, J.L.9
Puviindran, V.10
-
50
-
-
84864587817
-
Dissection of complex adult traits in a mouse synthetic population
-
Burke DT, Kozloff KM, Chen S, West JL, Wilkowski JM, Goldstein SA, Miller RA, Galecki AT: Dissection of complex adult traits in a mouse synthetic population. Genome Res 2012, 22:1549-1557.
-
(2012)
Genome Res
, vol.22
, pp. 1549-1557
-
-
Burke, D.T.1
Kozloff, K.M.2
Chen, S.3
West, J.L.4
Wilkowski, J.M.5
Goldstein, S.A.6
Miller, R.A.7
Galecki, A.T.8
-
51
-
-
84908077262
-
Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population
-
Wu Y, Williams EG, Dubuis S, Mottis A, Jovaisaite V, Houten SM, Argmann CA, Faridi P, Wolski W, Kutalik Z, et al.: Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population. Cell 2014, 158:1415-1430.
-
(2014)
Cell
, vol.158
, pp. 1415-1430
-
-
Wu, Y.1
Williams, E.G.2
Dubuis, S.3
Mottis, A.4
Jovaisaite, V.5
Houten, S.M.6
Argmann, C.A.7
Faridi, P.8
Wolski, W.9
Kutalik, Z.10
-
52
-
-
40349083852
-
Evidence of different metabolic phenotypes in humans
-
Assfalg M, Bertini I, Colangiuli D, Luchinat C, Schäfer H, Schütz B, Spraul M: Evidence of different metabolic phenotypes in humans. Proc Natl Acad Sci 2008, 105:1420-1424.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 1420-1424
-
-
Assfalg, M.1
Bertini, I.2
Colangiuli, D.3
Luchinat, C.4
Schäfer, H.5
Schütz, B.6
Spraul, M.7
-
53
-
-
84922469439
-
Genomic variation Impact of regulatory variation from RNA to protein
-
Battle A, Khan Z, Wang SH, Mitrano A, Ford MJ, Pritchard JK, Gilad Y: Genomic variation. Impact of regulatory variation from RNA to protein. Science 2015, 347:664-667.
-
(2015)
Science
, vol.347
, pp. 664-667
-
-
Battle, A.1
Khan, Z.2
Wang, S.H.3
Mitrano, A.4
Ford, M.J.5
Pritchard, J.K.6
Gilad, Y.7
-
54
-
-
84975717746
-
Defining the consequences of genetic variation on a proteome-wide scale
-
Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP: Defining the consequences of genetic variation on a proteome-wide scale. Nature 2016, 534:500-505.
-
(2016)
Nature
, vol.534
, pp. 500-505
-
-
Chick, J.M.1
Munger, S.C.2
Simecek, P.3
Huttlin, E.L.4
Choi, K.5
Gatti, D.M.6
Raghupathy, N.7
Svenson, K.L.8
Churchill, G.A.9
Gygi, S.P.10
-
55
-
-
79959812980
-
Comparative analysis of proteome and transcriptome variation in mouse
-
Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, et al.: Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet 2011, 7, e1001393.
-
(2011)
PLoS Genet
, vol.7
-
-
Ghazalpour, A.1
Bennett, B.2
Petyuk, V.A.3
Orozco, L.4
Hagopian, R.5
Mungrue, I.N.6
Farber, C.R.7
Sinsheimer, J.8
Kang, H.M.9
Furlotte, N.10
-
56
-
-
84904325891
-
MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes
-
McAlister GC, Nusinow DP, Jedrychowski MP, Wühr M, Huttlin EL, Erickson BK, Rad R, Haas W, Gygi SP: MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes. Anal Chem 2014, 86:7150-7158.
-
(2014)
Anal Chem
, vol.86
, pp. 7150-7158
-
-
McAlister, G.C.1
Nusinow, D.P.2
Jedrychowski, M.P.3
Wühr, M.4
Huttlin, E.L.5
Erickson, B.K.6
Rad, R.7
Haas, W.8
Gygi, S.P.9
-
57
-
-
84987776166
-
Effects of low-fat diet and aging on metabolic profiles of Creb3l4 knockout mice
-
Kim T-H, Park J-M, Jo S-H, Kim M-Y, Nojima H, Ahn Y-H: Effects of low-fat diet and aging on metabolic profiles of Creb3l4 knockout mice. Nutr Diabetes 2015, 5, e179.
-
(2015)
Nutr Diabetes
, vol.5
-
-
Kim, T-H.1
Park, J-M.2
Jo, S-H.3
Kim, M-Y.4
Nojima, H.5
Ahn, Y-H.6
-
58
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, et al.: SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 2010, 464:121-125.
-
(2010)
Nature
, vol.464
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
Grueter, C.A.7
Harris, C.8
Biddinger, S.9
Ilkayeva, O.R.10
-
59
-
-
84992709113
-
Systems-level analysis of mechanisms regulating yeast metabolic flux
-
Hackett SR, Zanotelli VRT, Xu W, Goya J, Park JO, Perlman DH, Gibney PA, Botstein D, Storey JD, Rabinowitz JD: Systems-level analysis of mechanisms regulating yeast metabolic flux. Science 2016, 354. aaf2786.
-
(2016)
Science
, vol.354
, pp. aaf2786
-
-
Hackett, S.R.1
Zanotelli, V.R.T.2
Xu, W.3
Goya, J.4
Park, J.O.5
Perlman, D.H.6
Gibney, P.A.7
Botstein, D.8
Storey, J.D.9
Rabinowitz, J.D.10
-
60
-
-
84901640509
-
Genetic regulation of mouse liver metabolite levels
-
Ghazalpour A, Bennett BJ, Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang W, et al.: Genetic regulation of mouse liver metabolite levels. Mol Syst Biol 2014, 10:730.
-
(2014)
Mol Syst Biol
, vol.10
, pp. 730
-
-
Ghazalpour, A.1
Bennett, B.J.2
Shih, D.3
Che, N.4
Orozco, L.5
Pan, C.6
Hagopian, R.7
He, A.8
Kayne, P.9
Yang, W.10
-
61
-
-
77951125481
-
Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity
-
Fendt S-M, Buescher JM, Rudroff F, Picotti P, Zamboni N, Sauer U: Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity. Mol Syst Biol 2010, 6:356.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 356
-
-
Fendt, S-M.1
Buescher, J.M.2
Rudroff, F.3
Picotti, P.4
Zamboni, N.5
Sauer, U.6
-
62
-
-
77956274547
-
High-throughput profiling of amino acids in strains of the Saccharomyces cerevisiae deletion collection
-
Cooper SJ, Finney GL, Brown SL, Nelson SK, Hesselberth J, MacCoss MJ, Fields S: High-throughput profiling of amino acids in strains of the Saccharomyces cerevisiae deletion collection. Genome Res 2010, 20:1288-1296.
-
(2010)
Genome Res
, vol.20
, pp. 1288-1296
-
-
Cooper, S.J.1
Finney, G.L.2
Brown, S.L.3
Nelson, S.K.4
Hesselberth, J.5
MacCoss, M.J.6
Fields, S.7
-
63
-
-
84990961064
-
Functional metabolomics describes the yeast biosynthetic regulome
-
Mülleder M, Calvani E, Alam MT, Wang RK, Eckerstorfer F, Zelezniak A, Ralser M: Functional metabolomics describes the yeast biosynthetic regulome. Cell 2016, 167. 553-565.e12.
-
(2016)
Cell
, vol.167
, pp. 553-565.e12
-
-
Mülleder, M.1
Calvani, E.2
Alam, M.T.3
Wang, R.K.4
Eckerstorfer, F.5
Zelezniak, A.6
Ralser, M.7
-
64
-
-
84913588646
-
Largescale functional analysis of the roles of phosphorylation in yeast metabolic pathways
-
Schulz JC, Zampieri M, Wanka S, Mering C von, Sauer U: Largescale functional analysis of the roles of phosphorylation in yeast metabolic pathways. Sci Signal 2014, 7. rs6-rs6.
-
(2014)
Sci Signal
, vol.7
, pp. rs6-rs6
-
-
Schulz, J.C.1
Zampieri, M.2
Wanka, S.3
Mering, C.4
von Sauer, U.5
-
65
-
-
18844407538
-
Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast
-
Deutschbauer AM, Jaramillo DF, Proctor M, Kumm J, Hillenmeyer ME, Davis RW, Nislow C, Giaever G: Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics 2005, 169:1915-1925.
-
(2005)
Genetics
, vol.169
, pp. 1915-1925
-
-
Deutschbauer, A.M.1
Jaramillo, D.F.2
Proctor, M.3
Kumm, J.4
Hillenmeyer, M.E.5
Davis, R.W.6
Nislow, C.7
Giaever, G.8
-
66
-
-
85010842085
-
Genomewide landscape of gene-metabolome associations in Escherichia coli
-
Fuhrer T, Zampieri M, Sévin DC, Sauer U, Zamboni N: Genomewide landscape of gene-metabolome associations in Escherichia coli. Mol Syst Biol 2017, 13:907.
-
(2017)
Mol Syst Biol
, vol.13
, pp. 907
-
-
Fuhrer, T.1
Zampieri, M.2
Sévin, D.C.3
Sauer, U.4
Zamboni, N.5
-
67
-
-
79959687662
-
An integrated approach to characterize genetic interaction networks in yeast metabolism
-
Szappanos B, Kovács K, Szamecz B, Honti F, Costanzo M, BaryshnikovaA,Gelius-DietrichG, LercherMJ, JelasityM,MyersCL, et al.: An integrated approach to characterize genetic interaction networks in yeast metabolism. Nat Genet 2011, 43:656-662.
-
(2011)
Nat Genet
, vol.43
, pp. 656-662
-
-
Szappanos, B.1
Kovács, K.2
Szamecz, B.3
Honti, F.4
Costanzo, M.5
Baryshnikova, A.6
Gelius-Dietrich, G.7
Lercher, M.J.8
Jelasity, M.9
Myers, C.L.10
-
68
-
-
84903640685
-
Metabolomic characterization of knock-out mutants in Arabidopsis - development of a metabolite profiling database for knock-out mutants in Arabidopsis (MeKO)
-
Fukushima A, Kusano M, Mejia RF, Iwasa M, Kobayashi M, Hayashi N, Watanabe-Takahashi A, Narisawa T, Tohge T, Hur M, et al.: Metabolomic characterization of knock-out mutants in Arabidopsis - development of a metabolite profiling database for knock-out mutants in Arabidopsis (MeKO). Plant Physiol 2014, http://dx.doi.org/10.1104/pp.114.240986.
-
(2014)
Plant Physiol
-
-
Fukushima, A.1
Kusano, M.2
Mejia, R.F.3
Iwasa, M.4
Kobayashi, M.5
Hayashi, N.6
Watanabe-Takahashi, A.7
Narisawa, T.8
Tohge, T.9
Hur, M.10
-
69
-
-
79953719673
-
Chloroplast 2010: a database for large-scale phenotypic screening of Arabidopsis mutants
-
Lu Y, Savage LJ, Larson MD, Wilkerson CG, Last RL: Chloroplast 2010: a database for large-scale phenotypic screening of Arabidopsis mutants. Plant Physiol 2011, 155:1589-1600.
-
(2011)
Plant Physiol
, vol.155
, pp. 1589-1600
-
-
Lu, Y.1
Savage, L.J.2
Larson, M.D.3
Wilkerson, C.G.4
Last, R.L.5
-
70
-
-
84926175755
-
Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis thaliana using a genome-scale metabolic network
-
Kim T, Dreher K, Nilo-Poyanco R, Lee I, Fiehn O, Lange BM, Nikolau BJ, Sumner L, Welti R, Wurtele ES, et al.: Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis thaliana using a genome-scale metabolic network. Plant Physiol 2015, http://dx.doi.org/10.1104/ pp.114.252361.
-
(2015)
Plant Physiol
-
-
Kim, T.1
Dreher, K.2
Nilo-Poyanco, R.3
Lee, I.4
Fiehn, O.5
Lange, B.M.6
Nikolau, B.J.7
Sumner, L.8
Welti, R.9
Wurtele, E.S.10
-
71
-
-
84928723640
-
Dynamic phosphoproteomics reveals TORC1- dependent regulation of yeast nucleotide and amino acid biosynthesis
-
Oliveira AP, Ludwig C, Zampieri M, Weisser H, Aebersold R, Sauer U: Dynamic phosphoproteomics reveals TORC1- dependent regulation of yeast nucleotide and amino acid biosynthesis. Sci Signal 2015, 8. rs4-rs4.
-
(2015)
Sci Signal
, vol.8
, pp. rs4-rs4
-
-
Oliveira, A.P.1
Ludwig, C.2
Zampieri, M.3
Weisser, H.4
Aebersold, R.5
Sauer, U.6
-
72
-
-
81355127364
-
a- Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition
-
Doucette CD, Schwab DJ, Wingreen NS, Rabinowitz JD: a- Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition. Nat Chem Biol 2011, 7:894-901.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 894-901
-
-
Doucette, C.D.1
Schwab, D.J.2
Wingreen, N.S.3
Rabinowitz, J.D.4
-
73
-
-
84988037648
-
PhenoMeter: a metabolome database search tool using statistical similarity matching of metabolic phenotypes for high-confidence detection of functional links [Internet]
-
Carroll AJ, Zhang P, Whitehead L, Kaines S, Tcherkez G, Badger MR: PhenoMeter: a metabolome database search tool using statistical similarity matching of metabolic phenotypes for high-confidence detection of functional links [Internet] Front Bioeng Biotechnol 2015, 3.
-
(2015)
Front Bioeng Biotechnol
, pp. 3
-
-
Carroll, A.J.1
Zhang, P.2
Whitehead, L.3
Kaines, S.4
Tcherkez, G.5
Badger, M.R.6
-
74
-
-
85019193043
-
Nontargeted metabolomics reveals the multilevel response to antibiotic perturbations
-
Zampieri M, Zimmermann M, Claassen M, Sauer U: Nontargeted metabolomics reveals the multilevel response to antibiotic perturbations. Cell Rep 2017, 19:1214-1228.
-
(2017)
Cell Rep
, vol.19
, pp. 1214-1228
-
-
Zampieri, M.1
Zimmermann, M.2
Claassen, M.3
Sauer, U.4
-
75
-
-
84971009551
-
Chemogenomics and orthologybased design of antibiotic combination therapies [Internet]
-
Chandrasekaran S, Cokol-Cakmak M, Sahin N, Yilancioglu K, Kazan H, Collins JJ, Cokol M: Chemogenomics and orthologybased design of antibiotic combination therapies [Internet] Mol Syst Biol 2016, 12.
-
(2016)
Mol Syst Biol
, pp. 12
-
-
Chandrasekaran, S.1
Cokol-Cakmak, M.2
Sahin, N.3
Yilancioglu, K.4
Kazan, H.5
Collins, J.J.6
Cokol, M.7
-
76
-
-
21444452397
-
Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks
-
di Bernardo D, Thompson MJ, Gardner TS, Chobot SE, Eastwood EL, Wojtovich AP, Elliott SJ, Schaus SE, Collins JJ: Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks. Nat Biotechnol 2005, 23: 377-383.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 377-383
-
-
di Bernardo, D.1
Thompson, M.J.2
Gardner, T.S.3
Chobot, S.E.4
Eastwood, E.L.5
Wojtovich, A.P.6
Elliott, S.J.7
Schaus, S.E.8
Collins, J.J.9
-
77
-
-
84957068722
-
Microbial metabolomics in open microscale platforms
-
Barkal LJ, Theberge AB, Guo C-J, Spraker J, Rappert L, Berthier J, Brakke KA, Wang CCC, Beebe DJ, Keller NP, et al.: Microbial metabolomics in open microscale platforms. Nat Commun 2016, 7:10610.
-
(2016)
Nat Commun
, vol.7
, pp. 10610
-
-
Barkal, L.J.1
Theberge, A.B.2
Guo, C-J.3
Spraker, J.4
Rappert, L.5
Berthier, J.6
Brakke, K.A.7
Wang, C.C.C.8
Beebe, D.J.9
Keller, N.P.10
-
78
-
-
85041927917
-
Metabolic modelbased integration of microbiome taxonomic and metabolomic profiles elucidates mechanistic links between ecological and metabolic variation
-
Noecker C, Eng A, Srinivasan S, Theriot CM, Young VB, Jansson JK, Fredricks DN, Borenstein E: Metabolic modelbased integration of microbiome taxonomic and metabolomic profiles elucidates mechanistic links between ecological and metabolic variation. mSystems 2016, 1. e00013-15.
-
(2016)
mSystems
, vol.1
-
-
Noecker, C.1
Eng, A.2
Srinivasan, S.3
Theriot, C.M.4
Young, V.B.5
Jansson, J.K.6
Fredricks, D.N.7
Borenstein, E.8
-
79
-
-
84925004475
-
CYP2C9 genotype vs. Metabolic phenotype for individual drug dosing-a correlation analysis using Flurbiprofen as probe drug [Internet]
-
Vogl S, Lutz RW, Schönfelder G, Lutz WK: CYP2C9 genotype vs. Metabolic phenotype for individual drug dosing-a correlation analysis using Flurbiprofen as probe drug [Internet] PLoS ONE 2015, 10.
-
(2015)
PLoS ONE
, pp. 10
-
-
Vogl, S.1
Lutz, R.W.2
Schönfelder, G.3
Lutz, W.K.4
-
80
-
-
83355177201
-
A system-level approach for deciphering the transcriptional response to prion infection
-
Zampieri M, Legname G, Segrè D, Altafini C: A system-level approach for deciphering the transcriptional response to prion infection. Bioinformatics 2011, 27:3407-3414.
-
(2011)
Bioinformatics
, vol.27
, pp. 3407-3414
-
-
Zampieri, M.1
Legname, G.2
Segrè, D.3
Altafini, C.4
-
81
-
-
84862992788
-
Body fat free mass is associated with the serum metabolite profile in a population-based study
-
Jourdan C, Petersen A-K, Gieger C, Döring A, Illig T, Wang- Sattler R, Meisinger C, Peters A, Adamski J, Prehn C, et al.: Body fat free mass is associated with the serum metabolite profile in a population-based study. PLOS ONE 2012, 7, e40009.
-
(2012)
PLOS ONE
, vol.7
-
-
Jourdan, C.1
Petersen, A-K.2
Gieger, C.3
Döring, A.4
Illig, T.5
Wang-Sattler, R.6
Meisinger, C.7
Peters, A.8
Adamski, J.9
Prehn, C.10
-
82
-
-
84867291398
-
Detection of transcriptional triggers in the dynamics of microbial growth: application to the respiratorily versatile bacterium Shewanella oneidensis
-
Beg QK, Zampieri M, Klitgord N, Collins SB, Altafini C, Serres MH, Segrè D: Detection of transcriptional triggers in the dynamics of microbial growth: application to the respiratorily versatile bacterium Shewanella oneidensis. Nucleic Acids Res 2012, 40: 7132-7149.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 7132-7149
-
-
Beg, Q.K.1
Zampieri, M.2
Klitgord, N.3
Collins, S.B.4
Altafini, C.5
Serres, M.H.6
Segrè, D.7
-
83
-
-
79251567361
-
Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data
-
Krumsiek J, Suhre K, Illig T, Adamski J, Theis FJ: Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data. BMC Syst Biol 2011, 5: 21.
-
(2011)
BMC Syst Biol
, vol.5
, pp. 21
-
-
Krumsiek, J.1
Suhre, K.2
Illig, T.3
Adamski, J.4
Theis, F.J.5
-
84
-
-
85016250410
-
Metabolic constraints on the evolution of antibiotic resistance
-
Zampieri M, Enke T, Chubukov V, Ricci V, Piddock L, Sauer U: Metabolic constraints on the evolution of antibiotic resistance. Mol Syst Biol 2017, 13:917.
-
(2017)
Mol Syst Biol
, vol.13
, pp. 917
-
-
Zampieri, M.1
Enke, T.2
Chubukov, V.3
Ricci, V.4
Piddock, L.5
Sauer, U.6
-
85
-
-
84924388543
-
Metabolomics integrated elementary flux mode analysis in large metabolic networks
-
Gerstl MP, Ruckerbauer DE, Mattanovich D, Jungreuthmayer C, Zanghellini J: Metabolomics integrated elementary flux mode analysis in large metabolic networks. Sci Rep 2015, 5:8930.
-
(2015)
Sci Rep
, vol.5
, pp. 8930
-
-
Gerstl, M.P.1
Ruckerbauer, D.E.2
Mattanovich, D.3
Jungreuthmayer, C.4
Zanghellini, J.5
-
86
-
-
84990177186
-
Multi-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coli
-
Kim M, Rai N, Zorraquino V, Tagkopoulos I: Multi-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coli. Nat Commun 2016, 7:13090.
-
(2016)
Nat Commun
, vol.7
, pp. 13090
-
-
Kim, M.1
Rai, N.2
Zorraquino, V.3
Tagkopoulos, I.4
-
87
-
-
84884659937
-
Steady-state metabolite concentrations reflect a balance between maximizing enzyme efficiency and minimizing total metabolite load [Internet]
-
Tepper N, Noor E, Amador-Noguez D, Haraldsdóttir HS, Milo R, Rabinowitz J, Liebermeister W, Shlomi T: Steady-state metabolite concentrations reflect a balance between maximizing enzyme efficiency and minimizing total metabolite load [Internet] PLoS ONE 2013, 8.
-
(2013)
PLoS ONE
, pp. 8
-
-
Tepper, N.1
Noor, E.2
Amador-Noguez, D.3
Haraldsdóttir, H.S.4
Milo, R.5
Rabinowitz, J.6
Liebermeister, W.7
Shlomi, T.8
-
88
-
-
84996565906
-
Illuminating a plant's tissue-specific metabolic diversity using computational metabolomics and information theory
-
Li D, Heiling S, Baldwin IT, Gaquerel E: Illuminating a plant's tissue-specific metabolic diversity using computational metabolomics and information theory. Proc Natl Acad Sci 2016, 113:E7610-E7618.
-
(2016)
Proc Natl Acad Sci
, vol.113
, pp. E7610-E7618
-
-
Li, D.1
Heiling, S.2
Baldwin, I.T.3
Gaquerel, E.4
-
89
-
-
77954197778
-
Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model
-
Yizhak K, Benyamini T, Liebermeister W, Ruppin E, Shlomi T: Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model. Bioinformatics 2010, 26:i255-i260.
-
(2010)
Bioinformatics
, vol.26
, pp. i255-i260
-
-
Yizhak, K.1
Benyamini, T.2
Liebermeister, W.3
Ruppin, E.4
Shlomi, T.5
-
90
-
-
85045337575
-
Enzymes and substrates are balanced at minimal combined mass concentration in vivo
-
Dourado H, Maurino VG, Lercher MJ: Enzymes and substrates are balanced at minimal combined mass concentration in vivo. bioRxiv 2017, http://dx.doi.org/10.1101/128009.
-
(2017)
bioRxiv
-
-
Dourado, H.1
Maurino, V.G.2
Lercher, M.J.3
-
91
-
-
84883361148
-
Flux imbalance analysis and the sensitivity of cellular growth to changes in metabolite pools
-
Reznik E, Mehta P, Segrè D: Flux imbalance analysis and the sensitivity of cellular growth to changes in metabolite pools. PLOS Comput Biol 2013, 9, e1003195.
-
(2013)
PLOS Comput Biol
, vol.9
-
-
Reznik, E.1
Mehta, P.2
Segrè, D.3
-
92
-
-
78049255973
-
Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis
-
Chandrasekaran S, Price ND: Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis. Proc Natl Acad Sci 2010, 107:17845-17850.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 17845-17850
-
-
Chandrasekaran, S.1
Price, N.D.2
-
93
-
-
85011355677
-
Systematic analysis of transcriptional and post-transcriptional regulation of metabolism in yeast
-
Gonçalves E, Raguz Nakic Z, Zampieri M, Wagih O, Ochoa D, Sauer U, Beltrao P, Saez-Rodriguez J: Systematic analysis of transcriptional and post-transcriptional regulation of metabolism in yeast. PLoS Comput Biol 2017, 13, e1005297.
-
(2017)
PLoS Comput Biol
, vol.13
-
-
Gonçalves, E.1
Raguz Nakic, Z.2
Zampieri, M.3
Wagih, O.4
Ochoa, D.5
Sauer, U.6
Beltrao, P.7
Saez-Rodriguez, J.8
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