Metabolomic Identification of a Novel Pathway of Blood Pressure Regulation Involving Hexadecanedioate

Hypertension

Volumn 66, Issue 2, 2015, Pages 422-429

  Menni, Cristina ^a   Graham, Delyth ^b   Kastenmüller, Gabi ^c   Alharbi, Nora H J ^b   Alsanosi, Safaa Md ^b   Mcbride, Martin ^a   Mangino, Massimo ^b   Titcombe, Philip ^d   Shin, So Youn ^e,f   Psatha, Maria ^a   Geisendorfer, Thomas ^g   Huber, Anja ^g   Peters, Annette ^c   Wang Sattler, Rui ^c   Xu, Tao ^c   Brosnan, Mary Julia ^h   Trimmer, Jeff ⁱ   Reichel, Christian ^g   Mohney, Robert P ^j   Soranzo, Nicole ^e   Edwards, Mark H ^d   Cooper, Cyrus ^d,k   Church, Alistair C ^l   Suhre, Karsten ^c,m   Gieger, Christian ^c   Dominiczak, Anna F ^b   Spector, Tim D ^a   Padmanabhan, Sandosh ^b   Valdes, Ana M ^a,n   more..

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^f UNIVERSITY OF BRISTOL   (United Kingdom)

^g Seibersdorf Labor GmbH   (Austria)

^h PFIZER INC   (United States)

ⁱ BioElectron Technology Corporation   (United States)

^j METABOLON INC   (United States)

^k UNIVERSITY OF OXFORD   (United Kingdom)

^l GOLDEN JUBILEE NATIONAL HOSPITAL   (United Kingdom)

^m QATAR FOUNDATION   (Qatar)

ⁿ UNIVERSITY OF NOTTINGHAM   (United Kingdom)

more..

Author keywords

Blood pressure; Fatty acid synthases; Hypertension; Metabolomics; Mortality

Indexed keywords

CARBACHOL; DICARBOXYLIC ACID; HEXADECANEDIOATE; NORADRENALIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG; HEXADECANEDIOIC ACID; PALMITIC ACID DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY RESISTANCE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR MORTALITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ELEVATED BLOOD PRESSURE; FEMALE; HUMAN; MALE; MESENTERIC ARTERY; METABOLITE; METABOLOMICS; NONHUMAN; PRIORITY JOURNAL; RAT; SHIFT TO THE LEFT; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT; SURVIVAL; SYSTOLIC BLOOD PRESSURE; WISTAR KYOTO RAT; AGED; ANIMAL; BLOOD PRESSURE; CROSS-SECTIONAL STUDY; DRUG EFFECTS; GERMANY; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; TWINS; UNITED KINGDOM;

ADULT; AGED; ANIMALS; BLOOD PRESSURE; CARBACHOL; CROSS-SECTIONAL STUDIES; ENGLAND; FEMALE; GERMANY; GREAT BRITAIN; HUMANS; MALE; METABOLOMICS; MIDDLE AGED; MODELS, ANIMAL; NOREPINEPHRINE; PALMITIC ACIDS; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION; SODIUM CHLORIDE;

EID: 84937560990     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.115.05544     Document Type: Article

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