Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks

Nature Biotechnology

Volumn 23, Issue 3, 2005, Pages 377-383

  Bernardo, Diego Di ^a   Thompson, Michael J ^b   Gardner, Timothy S ^b   Chobot, Sarah E ^c   Eastwood, Erin L ^c,d   Wojtovich, Andrew P ^c   Elliott, Scan J ^c   Schaus, Scott E ^c,d   Collins, James J ^b  

^a TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^b Boston University   (United States)

^c NONE   (United States)

^d BOSTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DRUG DOSAGE; ENZYME INHIBITION; ENZYME KINETICS; RNA;

CHEMOGENOMIC PROFILING; GENE REGULATORY NETWORK; THIOREDOXIN REDUCTASE;

GENES;

1 PHENYL 1H TETRAZOL 5 YLSULFONYL BUTANENITRILE; AMITROLE; CHITIN; CYCLOHEXIMIDE; DNA; DYCLONINE; ERGOSTEROL; HISTIDINE; HYDROXYUREA; ITRACONAZOLE; MESSENGER RNA; MEVINOLIN; NIKKOMYCIN; REACTIVE OXYGEN METABOLITE; TERBINAFINE; TETRAZOLE DERIVATIVE; THIOREDOXIN; THIOREDOXIN REDUCTASE; TUNICAMYCIN; UNCLASSIFIED DRUG; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; BIOSYNTHESIS; CANCER CELL CULTURE; CELL GROWTH; DNA DAMAGE; DNA MICROARRAY; DNA REPLICATION; DRUG RESEARCH; DRUG TARGETING; ENZYME ASSAY; FUNGUS GROWTH; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; NONHUMAN; OXIDATION REDUCTION REACTION; PHARMACOGENOMICS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STEROID METABOLISM; STEROL SYNTHESIS; ALGORITHM; ARTIFICIAL INTELLIGENCE; BIOLOGICAL MODEL; COMPUTER SIMULATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFECT; EVALUATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METHODOLOGY; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN ENGINEERING; SIGNAL TRANSDUCTION; STATISTICAL MODEL;

FUNGI; SACCHAROMYCES CEREVISIAE;

ALGORITHMS; ARTIFICIAL INTELLIGENCE; COMPUTER SIMULATION; DRUG DELIVERY SYSTEMS; DRUG DESIGN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MODELS, BIOLOGICAL; MODELS, STATISTICAL; PROTEIN ENGINEERING; PROTEIN INTERACTION MAPPING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; THIOREDOXIN; THIOREDOXIN REDUCTASE (NADPH);

EID: 21444452397     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1075     Document Type: Article

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