-
1
-
-
48249126806
-
The prion's elusive reason for being
-
Aguzzi, A. et al. (2008) The prion's elusive reason for being. Annu. Rev. Neurosci., 31, 439-477.
-
(2008)
Annu. Rev. Neurosci.
, vol.31
, pp. 439-477
-
-
Aguzzi, A.1
-
2
-
-
33645307955
-
Inference of gene regulatory networks and compound mode of action from time course gene expression profiles
-
Bansal, M. et al. (2006) Inference of gene regulatory networks and compound mode of action from time course gene expression profiles. Bioinformatics, 22, 815-822.
-
(2006)
Bioinformatics
, vol.22
, pp. 815-822
-
-
Bansal, M.1
-
3
-
-
16844376909
-
Reverse engineering of regulatory networks in human b cells
-
Basso, K. et al. (2005) Reverse engineering of regulatory networks in human b cells. Nat. Genet., 37, 382-390.
-
(2005)
Nat. Genet.
, vol.37
, pp. 382-390
-
-
Basso, K.1
-
4
-
-
75449098078
-
Gene expression profiling to identify druggable targets in prion diseases
-
Benetti, F. et al. (2010) Gene expression profiling to identify druggable targets in prion diseases. Exp. Opin. Drug Discov., 5, 177-202.
-
(2010)
Exp. Opin. Drug Discov.
, vol.5
, pp. 177-202
-
-
Benetti, F.1
-
5
-
-
42649090113
-
Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism
-
Berman, D.E. et al. (2008) Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism. Nat. Neurosci., 11, 547-554.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 547-554
-
-
Berman, D.E.1
-
6
-
-
77649091387
-
Axonal prion protein is required for peripheral myelin maintenance
-
Bremer, J. et al. (2010) Axonal prion protein is required for peripheral myelin maintenance. Nat. Neurosci., 13, 310-318.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 310-318
-
-
Bremer, J.1
-
7
-
-
20344394154
-
Anchorless prion protein results in infectious amyloid disease without clinical scrapie
-
Chesebro, B. et al. (2005) Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science, 308, 1435-1439.
-
(2005)
Science
, vol.308
, pp. 1435-1439
-
-
Chesebro, B.1
-
8
-
-
21444452397
-
Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks
-
di Bernardo, D. et al. (2005) Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks. Nat. Biotechnol., 23, 377-383.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 377-383
-
-
di Bernardo, D.1
-
9
-
-
33846400424
-
Large-scale mapping and validation of escherichia coli transcriptional regulation from a compendium of expression profiles
-
Faith, J.J. et al. (2007) Large-scale mapping and validation of escherichia coli transcriptional regulation from a compendium of expression profiles. PLoS Biol., 5.
-
(2007)
PLoS Biol.
, vol.5
-
-
Faith, J.J.1
-
10
-
-
0032949115
-
Expression of proteins linked to exocytosis and neurotransmission in patients with Creutzfeldt-Jakob disease
-
Ferrer, I. et al. (1999) Expression of proteins linked to exocytosis and neurotransmission in patients with Creutzfeldt-Jakob disease. Neurobiol. Dis., 6, 92-100.
-
(1999)
Neurobiol. Dis.
, vol.6
, pp. 92-100
-
-
Ferrer, I.1
-
11
-
-
31144460030
-
Functional amyloid formation within mammalian tissue
-
Fowler, D.M. et al. (2006) Functional amyloid formation within mammalian tissue. PLoS Biol., 4.
-
(2006)
PLoS Biol.
, vol.4
-
-
Fowler, D.M.1
-
12
-
-
0038048325
-
Inferring genetic networks and identifying compound mode of action via expression profiling
-
Gardner, T.S. et al. (2003) Inferring genetic networks and identifying compound mode of action via expression profiling. Science, 301, 102-105.
-
(2003)
Science
, vol.301
, pp. 102-105
-
-
Gardner, T.S.1
-
13
-
-
48149098006
-
A computational analysis of protein-protein interaction networks in neurodegenerative diseases
-
Goñi, J. et al. (2008) A computational analysis of protein-protein interaction networks in neurodegenerative diseases. BMC Syst. Biol., 2, 52.
-
(2008)
BMC Syst. Biol.
, vol.2
, pp. 52
-
-
Goñi, J.1
-
14
-
-
79952578947
-
Protein-only mechanism induces selfperpetuating changes in the activity of neuronal aplysia cytoplasmic polyadenylation element binding protein (cpeb)
-
Heinrich, S.U. and Lindquist, S. (2011) Protein-only mechanism induces selfperpetuating changes in the activity of neuronal aplysia cytoplasmic polyadenylation element binding protein (cpeb). Proc. Natl Acad. Sci. USA, 108, 2999-3004.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 2999-3004
-
-
Heinrich, S.U.1
Lindquist, S.2
-
15
-
-
63149151206
-
Asystems approach to prion disease
-
Hwang, D. et al. (2009)Asystems approach to prion disease. Mol. Syst. Biol., 5, 252-252.
-
(2009)
Mol. Syst. Biol.
, vol.5
, pp. 252-1252
-
-
Hwang, D.1
-
16
-
-
38949106949
-
Differences in the transcriptional responses induced by theileria annulata infection in bovine monocytes derived from resistant and susceptible cattle breeds
-
Jensen, K. et al. (2008) Differences in the transcriptional responses induced by theileria annulata infection in bovine monocytes derived from resistant and susceptible cattle breeds. Int. J. Parasitol., 38, 313-325.
-
(2008)
Int. J. Parasitol.
, vol.38
, pp. 313-325
-
-
Jensen, K.1
-
17
-
-
34247589262
-
Simvastatin treatment prolongs the survival of scrapie-infected mice
-
Kempster, S. et al. (2007) Simvastatin treatment prolongs the survival of scrapie-infected mice. Neuroreport, 18, 479-482.
-
(2007)
Neuroreport
, vol.18
, pp. 479-482
-
-
Kempster, S.1
-
18
-
-
1942485480
-
The cellular prion protein (prpc) prevents apoptotic neuronal cell death and mitochondrial dysfunction induced by serum deprivation
-
Kim, B.H. et al. (2004) The cellular prion protein (prpc) prevents apoptotic neuronal cell death and mitochondrial dysfunction induced by serum deprivation. Brain Res. Mol. Brain Res., 124, 40-50.
-
(2004)
Brain Res. Mol Brain Res.
, vol.124
, pp. 40-50
-
-
Kim, B.H.1
-
19
-
-
0141632823
-
New inhibitors of scrapie-associated prion protein formation in a library of 2000 drugs and natural products
-
Kocisko, D.A. et al. (2003) New inhibitors of scrapie-associated prion protein formation in a library of 2000 drugs and natural products. J. Virol., 77, 10288-10294.
-
(2003)
J. Virol.
, vol.77
, pp. 10288-10294
-
-
Kocisko, D.A.1
-
20
-
-
0036901006
-
Disease-associated prion protein in vessel walls
-
Koperek, O. et al. (2002) Disease-associated prion protein in vessel walls. Am. J. Pathol., 161, 1979-1984.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1979-1984
-
-
Koperek, O.1
-
21
-
-
0042626139
-
Copper modulation of ion channels of prp[106-126] mutant prion peptide fragments
-
Kourie, J.I. et al. (2003) Copper modulation of ion channels of prp[106-126] mutant prion peptide fragments. J. Membr. Biol., 193, 35-45.
-
(2003)
J. Membr. Biol.
, vol.193
, pp. 35-45
-
-
Kourie, J.I.1
-
22
-
-
34548567227
-
The commonality of protein interaction networks determined in neurodegenerative disorders (NDDs)
-
Limviphuvadh, V. et al. (2007) The commonality of protein interaction networks determined in neurodegenerative disorders (NDDs). Bioinformatics, 23, 2129-2138.
-
(2007)
Bioinformatics
, vol.23
, pp. 2129-2138
-
-
Limviphuvadh, V.1
-
23
-
-
77951666584
-
A mouse protein interactome through combined literature mining with multiple sources of interaction evidence
-
Li, X. et al. (2009) A mouse protein interactome through combined literature mining with multiple sources of interaction evidence. Amino Acids, 38, 1237-1252.
-
(2009)
Amino Acids
, vol.38
, pp. 1237-1252
-
-
Li, X.1
-
24
-
-
0342322973
-
Immunohistochemical detection of apolipoprotein E within prion-associated lesions in squirrel monkey brains
-
Nakamura, S. et al. (2000) Immunohistochemical detection of apolipoprotein E within prion-associated lesions in squirrel monkey brains. Acta Neuropathol., 100, 365-370.
-
(2000)
Acta Neuropathol
, vol.100
, pp. 365-370
-
-
Nakamura, S.1
-
25
-
-
20444462264
-
Altered behavioural response to acute stress in mice lacking cellular prion protein
-
Nico, P.B. et al. (2005) Altered behavioural response to acute stress in mice lacking cellular prion protein. Behav. Brain Res., 162, 173-181.
-
(2005)
Behav. Brain Res.
, vol.162
, pp. 173-181
-
-
Nico, P.B.1
-
26
-
-
67449149931
-
Prp© activation induces neurite outgrowth and differentiation in pc12 cells: role for caveolin-1 in the signal transduction pathway
-
Pantera, B. et al. (2009) Prp© activation induces neurite outgrowth and differentiation in pc12 cells: role for caveolin-1 in the signal transduction pathway. J. Neurochem., 110, 194-207.
-
(2009)
J. Neurochem.
, vol.110
, pp. 194-207
-
-
Pantera, B.1
-
27
-
-
0019399903
-
Disorders of glutamate metabolism and neurological dysfunction
-
Prusiner, S.B. (1981) Disorders of glutamate metabolism and neurological dysfunction. Annu. Rev. Med., 32, 521-542.
-
(1981)
Annu. Rev. Med.
, vol.32
, pp. 521-542
-
-
Prusiner, S.B.1
-
28
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner, S.B. (1982) Novel proteinaceous infectious particles cause scrapie. Science, 216, 136-144.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
29
-
-
18644383026
-
Truncated prion protein and doppel are myelinotoxic in the absence of oligodendrocytic PrPC
-
Radovanovic, I. et al. (2005) Truncated prion protein and doppel are myelinotoxic in the absence of oligodendrocytic PrPC. J. Neurosci., 25, 4879-4888.
-
(2005)
J. Neurosci.
, vol.25
, pp. 4879-4888
-
-
Radovanovic, I.1
-
30
-
-
77955595618
-
Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR
-
Roffé, M. et al. (2010) Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR. Proc. Natl Acad. Sci. USA, 107, 13147-13152.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 13147-13152
-
-
Roffé, M.1
-
31
-
-
75549091794
-
Corum: the comprehensive resource of mammalian protein complexes-2009
-
Ruepp, A. et al. (2010) Corum: the comprehensive resource of mammalian protein complexes-2009. Nucleic Acids Res., 38, 497-501.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 497-501
-
-
Ruepp, A.1
-
32
-
-
84887212358
-
The comprehensive native interactome of a fully functional tagged prion protein
-
Rutishauser, D. et al. (2009) The comprehensive native interactome of a fully functional tagged prion protein. PLoS One, 4.
-
(2009)
PLoS One
, vol.4
-
-
Rutishauser, D.1
-
33
-
-
0036457102
-
Developmental expression of the cellular prion protein in elongating axons
-
Salès, N. et al. (2002) Developmental expression of the cellular prion protein in elongating axons. Eur. J. Neurosci., 15, 1163-1177.
-
(2002)
Eur. J. Neurosci.
, vol.15
, pp. 1163-1177
-
-
Salès, N.1
-
34
-
-
12544258339
-
Altered interaction and expression of proteins involved in neurosecretion in scrapie-infected gt1-1 cells
-
Sandberg, M.K. and Löw, P. (2005) Altered interaction and expression of proteins involved in neurosecretion in scrapie-infected gt1-1 cells. J. Biol. Chem., 280, 1264-1271.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1264-1271
-
-
Sandberg, M.K.1
Löw, P.2
-
35
-
-
18544376071
-
Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth
-
Santuccione, A.et al. (2005) Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth. J. Cell Biol., 169, 341-354.
-
(2005)
J. Cell Biol.
, vol.169
, pp. 341-354
-
-
Santuccione, A.1
-
36
-
-
0346186101
-
A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia
-
Si, K. et al. (2003a) A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia. Cell, 115, 893-904.
-
(2003)
Cell
, vol.115
, pp. 893-904
-
-
Si, K.1
-
37
-
-
0348077417
-
A neuronal isoform of the aplysia CPEB has prion-like properties
-
Si, K. et al. (2003b) A neuronal isoform of the aplysia CPEB has prion-like properties. Cell, 115, 879-891.
-
(2003)
Cell
, vol.115
, pp. 879-891
-
-
Si, K.1
-
38
-
-
0036020892
-
A direct approach to false discovery rates
-
Storey, J.D. (2002) A direct approach to false discovery rates. J. R. Stat. Soc. Ser. B, 64, 479-498.
-
(2002)
J. R. Stat. Soc. Ser. B
, vol.64
, pp. 479-498
-
-
Storey, J.D.1
-
39
-
-
0028966735
-
Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform
-
Taraboulos, A. et al. (1995) Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. J. Cell. Biol., 129, 121-132.
-
(1995)
J. Cell. Biol.
, vol.129
, pp. 121-132
-
-
Taraboulos, A.1
-
40
-
-
33846953615
-
The low-density lipoprotein receptor-related protein 1 (lrp1) mediates the endocytosis of the cellular prion protein
-
Taylor, D.R. and Hooper, N.M. (2007) The low-density lipoprotein receptor-related protein 1 (lrp1) mediates the endocytosis of the cellular prion protein. Biochem. J., 402, 17-23.
-
(2007)
Biochem. J.
, vol.402
, pp. 17-23
-
-
Taylor, D.R.1
Hooper, N.M.2
-
41
-
-
33749236787
-
A systematic review of prion therapeutics in experimental models
-
Trevitt, C.R. and Collinge, J. (2006) A systematic review of prion therapeutics in experimental models. Brain, 129(Pt 9), 2241-2265.
-
(2006)
Brain
, vol.129
, Issue.PART 9
, pp. 2241-2265
-
-
Trevitt, C.R.1
Collinge, J.2
-
42
-
-
70249108504
-
Genome-wide identification of post-translational modulators of transcription factor activity in human B cells
-
Wang, K. et al. (2009) Genome-wide identification of post-translational modulators of transcription factor activity in human B cells. Nat. Biotechnol., 27, 829-839.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 829-839
-
-
Wang, K.1
-
43
-
-
73349140865
-
Interactome analyses identify ties of PRP and its mammalian paralogs to oligomannosidic n-glycans and endoplasmic reticulumderived chaperones
-
Watts, J.C. et al. (2009) Interactome analyses identify ties of PRP and its mammalian paralogs to oligomannosidic n-glycans and endoplasmic reticulumderived chaperones. PLoS Pathog., 5.
-
(2009)
PLoS Pathog
, vol.5
-
-
Watts, J.C.1
-
44
-
-
0030940607
-
Identification of candidate proteins binding to prion protein
-
Yehiely, F. et al. (1997)Identification of candidate proteins binding to prion protein. Neurobiol. Dis., 3, 339-355.
-
(1997)
Neurobiol. Dis.
, vol.3
, pp. 339-355
-
-
Yehiely, F.1
-
45
-
-
52149107867
-
Origin of co-expression patterns in E. coli and S. cerevisiae emerging from reverse engineering algorithms
-
Zampieri, M. et al. (2008) Origin of co-expression patterns in E. coli and S. cerevisiae emerging from reverse engineering algorithms. PLoS One, 3.
-
(2008)
PLoS One
, vol.3
-
-
Zampieri, M.1
|