메뉴 건너뛰기




Volumn 14, Issue 3, 2018, Pages 133-145

B cells in the pathogenesis of primary Sjögren syndrome

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; B CELL ACTIVATING FACTOR; BELIMUMAB; CHEMOKINE RECEPTOR CCR5; CXCL13 CHEMOKINE; INTERLEUKIN 21; MICRORNA; RHEUMATOID FACTOR; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 3; TNFSF13B PROTEIN, HUMAN;

EID: 85042334230     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2018.1     Document Type: Review
Times cited : (252)

References (159)
  • 1
    • 84945195754 scopus 로고    scopus 로고
    • Epidemiology of primary Sjogren's syndrome: A systematic review and meta-analysis
    • Qin, B. et al. Epidemiology of primary Sjogren's syndrome: a systematic review and meta-analysis. Ann. Rheum. Dis. 74, 1983-1989 (2015)
    • (2015) Ann. Rheum. Dis , vol.74 , pp. 1983-1989
    • Qin, B.1
  • 2
    • 1542357595 scopus 로고    scopus 로고
    • Estimating the prevalence among Caucasian women of primary Sjogren's syndrome in two general practices in Birmingham, U K Scand
    • Bowman, S. J., Ibrahim, G. H., Holmes, G., Hamburger, J. &Ainsworth, J. R. Estimating the prevalence among Caucasian women of primary Sjogren's syndrome in two general practices in Birmingham, U.K. Scand. J. Rheumatol. 33, 39-43 (2004)
    • (2004) J. Rheumatol , vol.33 , pp. 39-43
    • Bowman, S.J.1    Ibrahim, G.H.2    Holmes, G.3    Hamburger, J.4    Ainsworth, J.R.5
  • 3
    • 84878118827 scopus 로고    scopus 로고
    • Serum levels of B2 microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjogren's syndrome
    • Gottenberg, J. E. et al. Serum levels of B2 microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjogren's syndrome. Data at enrollment in the prospective ASSESS cohort. PLoS ONE 8, e59868 (2013)
    • (2013) Data at Enrollment in the Prospective ASSESS Cohort. PLoS ONE , vol.8 , pp. e59868
    • Gottenberg, J.E.1
  • 4
    • 84887077064 scopus 로고    scopus 로고
    • Autoantibodies present before symptom onset in primary Sjogren syndrome
    • Jonsson, R., Theander, E., Sjostrom, B., Brokstad, K. &Henriksson, G. Autoantibodies present before symptom onset in primary Sjogren syndrome. JAMA 310, 1854-1855 (2013)
    • (2013) JAMA , vol.310 , pp. 1854-1855
    • Jonsson, R.1    Theander, E.2    Sjostrom, B.3    Brokstad, K.4    Henriksson, G.5
  • 5
    • 84940118840 scopus 로고    scopus 로고
    • Prediction of Sjogren's syndrome years before diagnosis and identification of patients with early onset and severe disease course by autoantibody profiling
    • Theander, E. et al. Prediction of Sjogren's syndrome years before diagnosis and identification of patients with early onset and severe disease course by autoantibody profiling. Arthritis Rheumatol. 67, 2427-2436 (2015)
    • (2015) Arthritis Rheumatol , vol.67 , pp. 2427-2436
    • Theander, E.1
  • 6
    • 84873723410 scopus 로고    scopus 로고
    • The role of ectopic germinal centers in the immunopathology of primary Sjogren's syndrome: A systematic review
    • Risselada, A. P., Looije, M. F., Kruize, A. A., Bijlsma, J. W. J. &van Roon, J. A. G. The role of ectopic germinal centers in the immunopathology of primary Sjogren's syndrome: a systematic review. Semin. Arthritis Rheum. 42, 368-376 (2013)
    • (2013) Semin. Arthritis Rheum , vol.42 , pp. 368-376
    • Risselada, A.P.1    Looije, M.F.2    Kruize, A.A.3    Bijlsma, J.W.J.4    Van Roon, J.A.G.5
  • 7
    • 27844511909 scopus 로고    scopus 로고
    • The risk of lymphoma development in autoimmune diseases: A meta-analysis
    • Zintzaras, E., Voulgarelis, M. &Moutsopoulos, H. M. The risk of lymphoma development in autoimmune diseases: a meta-analysis. Arch. Intern. Med. 165, 2337-2344 (2005)
    • (2005) Arch. Intern. Med , vol.165 , pp. 2337-2344
    • Zintzaras, E.1    Voulgarelis, M.2    Moutsopoulos, H.M.3
  • 8
    • 84962091368 scopus 로고    scopus 로고
    • Rheumatoid factor and disease activity are independent predictors of lymphoma in primary Sjogren's Syndrome
    • Nocturne, G. et al. Rheumatoid factor and disease activity are independent predictors of lymphoma in primary Sjogren's Syndrome. Arthritis Rheumatol. 68, 977-985 (2016)
    • (2016) Arthritis Rheumatol , vol.68 , pp. 977-985
    • Nocturne, G.1
  • 9
    • 84883448195 scopus 로고    scopus 로고
    • Advances in understanding the pathogenesis of primary Sjogren's syndrome
    • Nocturne, G. &Mariette, X. Advances in understanding the pathogenesis of primary Sjogren's syndrome. Nat. Rev. Rheumatol. 9, 544-556 (2013)
    • (2013) Nat. Rev. Rheumatol , vol.9 , pp. 544-556
    • Nocturne, G.1    Mariette, X.2
  • 10
    • 84887116043 scopus 로고    scopus 로고
    • Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome
    • Lessard, C. J. et al. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome. Nat. Genet. 45, 1284-1292 (2013)
    • (2013) Nat. Genet , vol.45 , pp. 1284-1292
    • Lessard, C.J.1
  • 11
    • 84887085183 scopus 로고    scopus 로고
    • A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjogren's syndrome at 7q11.23
    • Li, Y. et al. A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjogren's syndrome at 7q11.23. Nat. Genet. 45, 1361-1365 (2013)
    • (2013) Nat. Genet , vol.45 , pp. 1361-1365
    • Li, Y.1
  • 12
    • 84892848904 scopus 로고    scopus 로고
    • Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome
    • Nocturne, G. et al. Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome. Blood 122, 4068-4076 (2013)
    • (2013) Blood , vol.122 , pp. 4068-4076
    • Nocturne, G.1
  • 13
    • 84940926601 scopus 로고    scopus 로고
    • Germline variation of TNFAIP3 in primary Sjogren's syndrome-associated lymphoma
    • Nocturne, G. et al. Germline variation of TNFAIP3 in primary Sjogren's syndrome-associated lymphoma. Ann. Rheum. Dis. 75, 780-783 (2016)
    • (2016) Ann. Rheum. Dis , vol.75 , pp. 780-783
    • Nocturne, G.1
  • 14
    • 85018819254 scopus 로고    scopus 로고
    • Genome-wide association analysis reveals genetic heterogeneity of Sjogren's syndrome according to ancestry
    • Taylor, K. E. et al. Genome-wide association analysis reveals genetic heterogeneity of Sjogren's syndrome according to ancestry. Arthritis Rheumatol. 69, 1294-1305 (2017)
    • (2017) Arthritis Rheumatol , vol.69 , pp. 1294-1305
    • Taylor, K.E.1
  • 15
    • 84896266991 scopus 로고    scopus 로고
    • Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjogren's syndrome
    • Altorok, N. et al. Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjogren's syndrome. Arthritis Rheumatol. 66, 731-739 (2014)
    • (2014) Arthritis Rheumatol , vol.66 , pp. 731-739
    • Altorok, N.1
  • 16
    • 84937598807 scopus 로고    scopus 로고
    • Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at risk loci in primary Sjogren's syndrome
    • Miceli-Richard, C. et al. Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at risk loci in primary Sjogren's syndrome. Ann. Rheum. Dis. 75, 933-940 (2016)
    • (2016) Ann. Rheum. Dis , vol.75 , pp. 933-940
    • Miceli-Richard, C.1
  • 17
    • 84958068675 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis in multiple tissues in primary Sjogren's syndrome reveals regulatory effects at interferon-induced genes
    • Imgenberg-Kreuz, J. et al. Genome-wide DNA methylation analysis in multiple tissues in primary Sjogren's syndrome reveals regulatory effects at interferon-induced genes. Ann. Rheum. Dis. 75, 2029-2036 (2016)
    • (2016) Ann. Rheum. Dis , vol.75 , pp. 2029-2036
    • Imgenberg-Kreuz, J.1
  • 18
    • 84960091697 scopus 로고    scopus 로고
    • Defective DNA methylation in salivary gland epithelial acini from patients with Sjogren's syndrome is associated with SSB gene expression, anti-SSB/La detection, and lymphocyte infiltration
    • Konsta, O. D. et al. Defective DNA methylation in salivary gland epithelial acini from patients with Sjogren's syndrome is associated with SSB gene expression, anti-SSB/La detection, and lymphocyte infiltration. J. Autoimmun. 68, 30-38 (2016)
    • (2016) J. Autoimmun , vol.68 , pp. 30-38
    • Konsta, O.D.1
  • 19
    • 84997796242 scopus 로고    scopus 로고
    • Epigenetic signatures of salivary gland inflammation in Sjogren's syndrome
    • Cole, M. B. et al. Epigenetic signatures of salivary gland inflammation in Sjogren's syndrome. Arthritis Rheumatol. 68, 2936-2944 (2016)
    • (2016) Arthritis Rheumatol , vol.68 , pp. 2936-2944
    • Cole, M.B.1
  • 20
    • 84875926964 scopus 로고    scopus 로고
    • Epigenetic dysregulation in salivary glands from patients with primary Sjogren's syndrome may be ascribed to infiltrating B cells
    • Thabet, Y. et al. Epigenetic dysregulation in salivary glands from patients with primary Sjogren's syndrome may be ascribed to infiltrating B cells. J. Autoimmun. 41, 175-181 (2013)
    • (2013) J. Autoimmun , vol.41 , pp. 175-181
    • Thabet, Y.1
  • 21
    • 84923247028 scopus 로고    scopus 로고
    • MicroRNA profiling in Chinese patients with primary Sjogren syndrome reveals elevated miRNA 181a in peripheral blood mononuclear cells
    • Peng, L. et al. MicroRNA profiling in Chinese patients with primary Sjogren syndrome reveals elevated miRNA 181a in peripheral blood mononuclear cells. J. Rheumatol. 41, 2208-2213 (2014)
    • (2014) J. Rheumatol , vol.41 , pp. 2208-2213
    • Peng, L.1
  • 22
    • 84911379428 scopus 로고    scopus 로고
    • MIR 146a and MIR 155 expression in PBMCs from patients with Sjogren's syndrome
    • Shi, H., Zheng, L., Zhang, P. &Yu, C. miR 146a and miR 155 expression in PBMCs from patients with Sjogren's syndrome. J. Oral Pathol. Med. 43, 792-797 (2014)
    • (2014) J. Oral Pathol. Med , vol.43 , pp. 792-797
    • Shi, H.1    Zheng, L.2    Zhang, P.3    Yu, C.4
  • 23
    • 79959720798 scopus 로고    scopus 로고
    • Altered MIR 146a expression in Sjogren's syndrome and its functional role in innate immunity
    • Pauley, K. M. et al. Altered miR 146a expression in Sjogren's syndrome and its functional role in innate immunity. Eur. J. Immunol. 41, 2029-2039 (2011)
    • (2011) Eur. J. Immunol , vol.41 , pp. 2029-2039
    • Pauley, K.M.1
  • 24
    • 79551656688 scopus 로고    scopus 로고
    • MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjogren's syndrome
    • Alevizos, I., Alexander, S., Turner, R. J. &Illei, G. G. MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjogren's syndrome. Arthritis Rheum. 63, 535-544 (2011)
    • (2011) Arthritis Rheum , vol.63 , pp. 535-544
    • Alevizos, I.1    Alexander, S.2    Turner, R.J.3    Illei, G.G.4
  • 25
    • 85039851612 scopus 로고    scopus 로고
    • Deregulation of microRNA expression in purified T and B lymphocytes from patients with primary Sjogren's syndrome
    • Wang-Renault, S. F. et al. Deregulation of microRNA expression in purified T and B lymphocytes from patients with primary Sjogren's syndrome. Ann. Rheum. Dis. 77, 133-140 (2018)
    • (2018) Ann. Rheum. Dis , vol.77 , pp. 133-140
    • Wang-Renault, S.F.1
  • 26
    • 0242270822 scopus 로고    scopus 로고
    • Infection of autoreactive B lymphocytes with EBV, causing chronic autoimmune diseases
    • Pender, M. P. Infection of autoreactive B lymphocytes with EBV, causing chronic autoimmune diseases. Trends Immunol. 24, 584-588 (2003)
    • (2003) Trends Immunol , vol.24 , pp. 584-588
    • Pender, M.P.1
  • 27
    • 0036284985 scopus 로고    scopus 로고
    • Alternate replication in B cells and epithelial cells switches tropism of Epstein-Barr virus
    • Borza, C. M. &Hutt-Fletcher, L. M. Alternate replication in B cells and epithelial cells switches tropism of Epstein-Barr virus. Nat. Med. 8, 594-599 (2002)
    • (2002) Nat. Med , vol.8 , pp. 594-599
    • Borza, C.M.1    Hutt-Fletcher, L.M.2
  • 28
    • 84907386953 scopus 로고    scopus 로고
    • What caused all these troubles, anyway? Epstein-Barr virus in Sjogren's syndrome reevaluated
    • Harley, J. B. &Zoller, E. E. What caused all these troubles, anyway? Epstein-Barr virus in Sjogren's syndrome reevaluated. Arthritis Rheumatol. 66, 2328-2330 (2014)
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2328-2330
    • Harley, J.B.1    Zoller, E.E.2
  • 29
    • 0032433666 scopus 로고    scopus 로고
    • Murine cytomegalovirus induces a Sjogren's syndrome-like disease in C57Bl/6 lpr/lpr mice
    • Fleck, M., Kern, E. R., Zhou, T., Lang, B. &Mountz, J. D. Murine cytomegalovirus induces a Sjogren's syndrome-like disease in C57Bl/6 lpr/lpr mice. Arthritis Rheum. 41, 2175-2184 (1998)
    • (1998) Arthritis Rheum , vol.41 , pp. 2175-2184
    • Fleck, M.1    Kern, E.R.2    Zhou, T.3    Lang, B.4    Mountz, J.D.5
  • 30
    • 70350488070 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3
    • Iwakiri, D. et al. Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3. J. Exp. Med. 206, 2091-2099 (2009)
    • (2009) J. Exp. Med , vol.206 , pp. 2091-2099
    • Iwakiri, D.1
  • 31
    • 0142197627 scopus 로고    scopus 로고
    • B cells under influence: Transformation of B cells by Epstein-Barr virus
    • Küppers, R. B cells under influence: transformation of B cells by Epstein-Barr virus. Nat. Rev. Immunol. 3, 801-812 (2003)
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 801-812
    • Küppers, R.1
  • 32
    • 0242495542 scopus 로고    scopus 로고
    • EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and April to induce T cellindependent Ig heavy chain class switching
    • He, B., Raab-Traub, N., Casali, P. &Cerutti, A. EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cellindependent Ig heavy chain class switching. J. Immunol. 171, 5215-5224 (2003)
    • (2003) J. Immunol , vol.171 , pp. 5215-5224
    • He, B.1    Raab-Traub, N.2    Casali, P.3    Cerutti, A.4
  • 33
    • 0035340982 scopus 로고    scopus 로고
    • Possible involvement of EBV-mediated a fodrin cleavage for organ-specific autoantigen in Sjogren's syndrome
    • Inoue, H. et al. Possible involvement of EBV-mediated a fodrin cleavage for organ-specific autoantigen in Sjogren's syndrome. J. Immunol. 166, 5801-5809 (2001)
    • (2001) J. Immunol , vol.166 , pp. 5801-5809
    • Inoue, H.1
  • 34
    • 84903393902 scopus 로고    scopus 로고
    • Implication of Epstein-Barr virus infection in disease-specific autoreactive B cell activation in ectopic lymphoid structures of Sjogren's syndrome
    • Croia, C. et al. Implication of Epstein-Barr virus infection in disease-specific autoreactive B cell activation in ectopic lymphoid structures of Sjogren's syndrome. Arthritis Rheumatol. 66, 2545-2557 (2014)
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2545-2557
    • Croia, C.1
  • 35
    • 84941703211 scopus 로고    scopus 로고
    • Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A
    • Minamitani, T. et al. Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A. Proc. Natl Acad. Sci. USA 112, 11612-11617 (2015)
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 11612-11617
    • Minamitani, T.1
  • 36
    • 85030611479 scopus 로고    scopus 로고
    • H1N1 vaccination in Sjogren's syndrome triggers polyclonal B cell activation and promotes autoantibody production
    • Brauner, S. et al. H1N1 vaccination in Sjogren's syndrome triggers polyclonal B cell activation and promotes autoantibody production. Ann. Rheum. Dis. 76, 1755-1763 (2017)
    • (2017) Ann. Rheum. Dis , vol.76 , pp. 1755-1763
    • Brauner, S.1
  • 37
    • 84899112356 scopus 로고    scopus 로고
    • The enemy within: Endogenous retroelements and autoimmune disease
    • Volkman, H. E. &Stetson, D. B. The enemy within: endogenous retroelements and autoimmune disease. Nat. Immunol. 15, 415-422 (2014)
    • (2014) Nat. Immunol , vol.15 , pp. 415-422
    • Volkman, H.E.1    Stetson, D.B.2
  • 38
    • 84919443956 scopus 로고    scopus 로고
    • MAVS, cGAS, and endogenous retroviruses in T independent B cell responses
    • Zeng, M. et al. MAVS, cGAS, and endogenous retroviruses in T independent B cell responses. Science 346, 1486-1492 (2014)
    • (2014) Science , vol.346 , pp. 1486-1492
    • Zeng, M.1
  • 39
    • 84992560627 scopus 로고    scopus 로고
    • Expression of long interspersed nuclear element 1 retroelements and induction of type i interferon in patients with systemic autoimmune disease
    • Mavragani, C. P. et al. Expression of long interspersed nuclear element 1 retroelements and induction of type I interferon in patients with systemic autoimmune disease. Arthritis Rheumatol. 68, 2686-2696 (2016)
    • (2016) Arthritis Rheumatol , vol.68 , pp. 2686-2696
    • Mavragani, C.P.1
  • 40
    • 75749101744 scopus 로고    scopus 로고
    • Long interspersed nuclear elements (LINE 1): Potential triggers of systemic autoimmune disease
    • Crow, M. K. Long interspersed nuclear elements (LINE 1): potential triggers of systemic autoimmune disease. Autoimmunity 43, 7-16 (2010)
    • (2010) Autoimmunity , vol.43 , pp. 7-16
    • Crow, M.K.1
  • 41
    • 84944810495 scopus 로고    scopus 로고
    • The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression
    • Hung, T. et al. The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression. Science 350, 455-459 (2015)
    • (2015) Science , vol.350 , pp. 455-459
    • Hung, T.1
  • 42
    • 0035478494 scopus 로고    scopus 로고
    • Bm1 Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjogren's syndrome
    • Bohnhorst, J. O., Bjorgan, M. B., Thoen, J. E., Natvig, J. B. &Thompson, K. M. Bm1 Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjogren's syndrome. J. Immunol. 167, 3610-3618 (2001)
    • (2001) J. Immunol , vol.167 , pp. 3610-3618
    • Bohnhorst, J.O.1    Bjorgan, M.B.2    Thoen, J.E.3    Natvig, J.B.4    Thompson, K.M.5
  • 43
    • 31044444154 scopus 로고    scopus 로고
    • BAFF-induced changes in B cell antigen receptor-containing lipid rafts in Sjogren's syndrome
    • Arbonneau, F. et al. BAFF-induced changes in B cell antigen receptor-containing lipid rafts in Sjogren's syndrome. Arthritis Rheum. 54, 115-126 (2006)
    • (2006) Arthritis Rheum , vol.54 , pp. 115-126
    • Arbonneau, F.1
  • 44
    • 85019157685 scopus 로고    scopus 로고
    • Enhanced Bruton's tyrosine kinase activity in peripheral blood B lymphocytes from patients with autoimmune disease
    • Corneth, O. B. J. et al. Enhanced Bruton's tyrosine kinase activity in peripheral blood B lymphocytes from patients with autoimmune disease. Arthritis Rheumatol. 69, 1313-1324 (2017)
    • (2017) Arthritis Rheumatol , vol.69 , pp. 1313-1324
    • Corneth, O.B.J.1
  • 45
    • 2642541037 scopus 로고    scopus 로고
    • Abnormalities in peripheral B cell memory of patients with primary Sjogren's syndrome
    • Hansen, A. et al. Abnormalities in peripheral B cell memory of patients with primary Sjogren's syndrome. Arthritis Rheum. 50, 1897-1908 (2004)
    • (2004) Arthritis Rheum , vol.50 , pp. 1897-1908
    • Hansen, A.1
  • 46
    • 84907385240 scopus 로고    scopus 로고
    • Primary Sjogren's syndrome is characterized by distinct phenotypic and transcriptional profiles of IgD+ unswitched memory B cells
    • Roberts, M. E. P. et al. Primary Sjogren's syndrome is characterized by distinct phenotypic and transcriptional profiles of IgD+ unswitched memory B cells. Arthritis Rheumatol. 66, 2558-2569 (2014)
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2558-2569
    • Roberts, M.E.P.1
  • 47
    • 84955335389 scopus 로고    scopus 로고
    • A comprehensive investigation on the distribution of circulating follicular T helper cells and B cell subsets in primary Sjogren's syndrome and systemic lupus erythematosus
    • Szabo, K., Papp, G., Szánto, A., Tarr, T. &Zeher, M. A comprehensive investigation on the distribution of circulating follicular T helper cells and B cell subsets in primary Sjogren's syndrome and systemic lupus erythematosus. Clin. Exp. Immunol. 183, 76-89 (2016)
    • (2016) Clin. Exp. Immunol , vol.183 , pp. 76-89
    • Szabo, K.1    Papp, G.2    Szánto, A.3    Tarr, T.4    Zeher, M.5
  • 48
    • 84865960201 scopus 로고    scopus 로고
    • B Cell populations and sub-populations in Sjogren's syndrome
    • Hamza, N., Bos, N. A. &Kallenberg, C. G. M. B Cell populations and sub-populations in Sjogren's syndrome. Presse Med. 41, e475-483 (2012)
    • (2012) Presse Med , vol.41 , pp. e475-483
    • Hamza, N.1    Bos, N.A.2    Kallenberg, C.G.M.3
  • 49
    • 0036676086 scopus 로고    scopus 로고
    • Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjogren's syndrome
    • Hansen, A. et al. Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjogren's syndrome. Arthritis Rheum. 46, 2160-2171 (2002)
    • (2002) Arthritis Rheum , vol.46 , pp. 2160-2171
    • Hansen, A.1
  • 50
    • 84961904335 scopus 로고    scopus 로고
    • Cytometry by time of flight immunophenotyping identifies a blood Sjogren's signature correlating with disease activity and glandular inflammation
    • Mingueneau, M. et al. Cytometry by time of flight immunophenotyping identifies a blood Sjogren's signature correlating with disease activity and glandular inflammation. J. Allergy Clin. Immunol. 137, 1809-1821.e12 (2016)
    • (2016) J. Allergy Clin. Immunol , vol.137 , pp. 1809-1821e12
    • Mingueneau, M.1
  • 51
    • 84937714861 scopus 로고    scopus 로고
    • Long-lived plasma cells are contained within the CD19(-)CD38(hi)CD138(+) subset in human bone marrow
    • Halliley, J. L. et al. Long-lived plasma cells are contained within the CD19(-)CD38(hi)CD138(+) subset in human bone marrow. Immunity 43, 132-145 (2015)
    • (2015) Immunity , vol.43 , pp. 132-145
    • Halliley, J.L.1
  • 52
    • 85030984024 scopus 로고    scopus 로고
    • Plasmablasts with a mucosal phenotype contribute to plasmacytosis in SLE
    • Mei, H. E. et al. Plasmablasts with a mucosal phenotype contribute to plasmacytosis in SLE. Arthritis Rheumatol. 69, 2018-2018 (2017)
    • (2017) Arthritis Rheumatol , vol.69 , pp. 2018
    • Mei, H.E.1
  • 53
    • 85021855071 scopus 로고    scopus 로고
    • A multicentre study of 95 biopsyproven cases of renal disease in primary Sjogren's syndrome
    • Jasiek, M. et al. A multicentre study of 95 biopsyproven cases of renal disease in primary Sjogren's syndrome. Rheumatology (Oxford) 56, 362-370 (2017)
    • (2017) Rheumatology (Oxford) , vol.56 , pp. 362-370
    • Jasiek, M.1
  • 54
    • 0032430377 scopus 로고    scopus 로고
    • Detection of anti Ro/SSA and anti La/SSB autoantibody-producing cells in salivary glands from patients with Sjogren's syndrome
    • Tengner, P., Halse, A. K., Haga, H. J., Jonsson, R. &Wahren-Herlenius, M. Detection of anti Ro/SSA and anti La/SSB autoantibody-producing cells in salivary glands from patients with Sjogren's syndrome. Arthritis Rheum. 41, 2238-2248 (1998)
    • (1998) Arthritis Rheum , vol.41 , pp. 2238-2248
    • Tengner, P.1    Halse, A.K.2    Haga, H.J.3    Jonsson, R.4    Wahren-Herlenius, M.5
  • 55
    • 33748872264 scopus 로고    scopus 로고
    • Development of nephritis but not sialadenitis in autoimmune-prone BAFF transgenic mice lacking marginal zone B cells
    • Fletcher, C. A. et al. Development of nephritis but not sialadenitis in autoimmune-prone BAFF transgenic mice lacking marginal zone B cells. Eur. J. Immunol. 36, 2504-2514 (2006)
    • (2006) Eur. J. Immunol , vol.36 , pp. 2504-2514
    • Fletcher, C.A.1
  • 56
    • 34848847145 scopus 로고    scopus 로고
    • Development of Sjogren's syndrome in nonobese diabetic-derived autoimmune-prone C57BL/6 NOD aec1Aec2 ice is dependent on complement component 3
    • Nguyen, C. Q., Kim, H., Cornelius, J. G. &Peck, A. B. Development of Sjogren's syndrome in nonobese diabetic-derived autoimmune-prone C57BL/6. NOD Aec1Aec2 mice is dependent on complement component 3. J. Immunol. 179, 2318-2329 (2007)
    • (2007) J. Immunol , vol.179 , pp. 2318-2329
    • Nguyen, C.Q.1    Kim, H.2    Cornelius, J.G.3    Peck, A.B.4
  • 57
    • 33749509230 scopus 로고    scopus 로고
    • Development of autoimmunity in IL 14a transgenic mice
    • Shen, L. et al. Development of autoimmunity in IL 14a transgenic mice. J. Immunol. 177, 5676-5686 (2006)
    • (2006) J. Immunol , vol.177 , pp. 5676-5686
    • Shen, L.1
  • 58
    • 84965029194 scopus 로고    scopus 로고
    • Central role for marginal zone B cells in an animal model of Sjogren's syndrome
    • Shen, L. et al. Central role for marginal zone B cells in an animal model of Sjogren's syndrome. Clin. Immunol. 168, 30-36 (2016)
    • (2016) Clin. Immunol , vol.168 , pp. 30-36
    • Shen, L.1
  • 59
    • 33745877307 scopus 로고    scopus 로고
    • Identification of transitional type II B cells in the salivary glands of patients with Sjogren's syndrome
    • Daridon, C. et al. Identification of transitional type II B cells in the salivary glands of patients with Sjogren's syndrome. Arthritis Rheum. 54, 2280-2288 (2006)
    • (2006) Arthritis Rheum , vol.54 , pp. 2280-2288
    • Daridon, C.1
  • 60
    • 84921342740 scopus 로고    scopus 로고
    • Sjogren syndromeassociated lymphomas: An update on pathogenesis and management
    • Nocturne, G. &Mariette, X. Sjogren syndromeassociated lymphomas: an update on pathogenesis and management. Br. J. Haematol. 168, 317-327 (2015)
    • (2015) Br. J. Haematol , vol.168 , pp. 317-327
    • Nocturne, G.1    Mariette, X.2
  • 61
    • 78049527643 scopus 로고    scopus 로고
    • Regulatory B cells in autoimmunity: Developments and controversies
    • Mauri, C. &Blair, P. A. Regulatory B cells in autoimmunity: developments and controversies. Nat. Rev. Rheumatol. 6, 636-643 (2010)
    • (2010) Nat. Rev. Rheumatol , vol.6 , pp. 636-643
    • Mauri, C.1    Blair, P.A.2
  • 62
    • 74649083783 scopus 로고    scopus 로고
    • CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients
    • Blair, P. A. et al. CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients. Immunity 32, 129-140 (2010)
    • (2010) Immunity , vol.32 , pp. 129-140
    • Blair, P.A.1
  • 63
    • 79954939552 scopus 로고    scopus 로고
    • Human T cells induce their own regulation through activation of B cells
    • Lemoine, S., Morva, A., Youinou, P. &Jamin, C. Human T cells induce their own regulation through activation of B cells. J. Autoimmun. 36, 228-238 (2011)
    • (2011) J. Autoimmun , vol.36 , pp. 228-238
    • Lemoine, S.1    Morva, A.2    Youinou, P.3    Jamin, C.4
  • 64
    • 84897942212 scopus 로고    scopus 로고
    • B10 cell regulation of health and disease
    • Candando, K. M., Lykken, J. M. &Tedder, T. F. B10 cell regulation of health and disease. Immunol. Rev. 259, 259-272 (2014)
    • (2014) Immunol. Rev , vol.259 , pp. 259-272
    • Candando, K.M.1    Lykken, J.M.2    Tedder, T.F.3
  • 65
    • 84960435612 scopus 로고    scopus 로고
    • A regulatory feedback between plasmacytoid dendritic cells and regulatory B cells is aberrant in systemic lupus erythematosus
    • Menon, M., Blair, P. A., Isenberg, D. A. &Mauri, C. A regulatory feedback between plasmacytoid dendritic cells and regulatory B cells is aberrant in systemic lupus erythematosus. Immunity 44, 683-697 (2016)
    • (2016) Immunity , vol.44 , pp. 683-697
    • Menon, M.1    Blair, P.A.2    Isenberg, D.A.3    Mauri, C.4
  • 66
    • 84902078796 scopus 로고    scopus 로고
    • Interleukin 35 induces regulatory B cells that suppress autoimmune disease
    • Wang, R. X. et al. Interleukin 35 induces regulatory B cells that suppress autoimmune disease. Nat. Med. 20, 633-641 (2014)
    • (2014) Nat. Med , vol.20 , pp. 633-641
    • Wang, R.X.1
  • 67
    • 84897027520 scopus 로고    scopus 로고
    • IL 35 producing B cells are critical regulators of immunity during autoimmune and infectious diseases
    • Shen, P. et al. IL 35 producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature 507, 366-370 (2014)
    • (2014) Nature , vol.507 , pp. 366-370
    • Shen, P.1
  • 68
    • 85031108452 scopus 로고    scopus 로고
    • Role of the IL 12/IL 35 balance in patients with Sjogren syndrome
    • Fogel, O. et al. Role of the IL 12/IL 35 balance in patients with Sjogren syndrome. J. Allergy Clin. Immunol. https://doi.org/10.1016/j.jaci.2017.07.041 (2017)
    • (2017) J. Allergy Clin. Immunol
    • Fogel, O.1
  • 69
    • 84855962862 scopus 로고    scopus 로고
    • B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
    • Puga, I. et al. B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nat. Immunol. 13, 170-180 (2011)
    • (2011) Nat. Immunol , vol.13 , pp. 170-180
    • Puga, I.1
  • 70
    • 84896631269 scopus 로고    scopus 로고
    • Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells
    • Magri, G. et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat. Immunol. 15, 354-364 (2014)
    • (2014) Nat. Immunol , vol.15 , pp. 354-364
    • Magri, G.1
  • 71
    • 85034958285 scopus 로고    scopus 로고
    • Patients with primary Sjogren's syndrome have alterations in absolute quantities of specific peripheral leucocyte populations
    • Davies, R. et al. Patients with primary Sjogren's syndrome have alterations in absolute quantities of specific peripheral leucocyte populations. Scand. J. Immunol. 86, 491-502 (2017)
    • (2017) Scand. J. Immunol , vol.86 , pp. 491-502
    • Davies, R.1
  • 72
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay, F. et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190, 1697-1710 (1999)
    • (1999) J. Exp. Med , vol.190 , pp. 1697-1710
    • Mackay, F.1
  • 73
    • 0037310430 scopus 로고    scopus 로고
    • The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome
    • Mariette, X. et al. The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome. Ann. Rheum. Dis. 62, 168-171 (2003)
    • (2003) Ann. Rheum. Dis , vol.62 , pp. 168-171
    • Mariette, X.1
  • 74
    • 1842583827 scopus 로고    scopus 로고
    • Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome
    • Lavie, F. et al. Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome. J. Pathol. 202, 496-502 (2004)
    • (2004) J. Pathol , vol.202 , pp. 496-502
    • Lavie, F.1
  • 75
    • 34247230559 scopus 로고    scopus 로고
    • Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjogren's syndrome
    • Daridon, C. et al. Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjogren's syndrome. Arthritis Rheum. 56, 1134-1144 (2007)
    • (2007) Arthritis Rheum , vol.56 , pp. 1134-1144
    • Daridon, C.1
  • 76
    • 38149090131 scopus 로고    scopus 로고
    • B Cell activating factor of the tumour necrosis factor family expression in blood monocytes and T cells from patients with primary Sjogren's syndrome
    • Lavie, F. et al. B Cell activating factor of the tumour necrosis factor family expression in blood monocytes and T cells from patients with primary Sjogren's syndrome. Scand. J. Immunol. 67, 185-192 (2008)
    • (2008) Scand. J. Immunol , vol.67 , pp. 185-192
    • Lavie, F.1
  • 77
    • 84901269992 scopus 로고    scopus 로고
    • Specific forms of BAFF favor BAFF receptor-mediated epithelial cell survival
    • Lahiri, A. et al. Specific forms of BAFF favor BAFF receptor-mediated epithelial cell survival. J. Autoimmun. 51, 30-37 (2014)
    • (2014) J. Autoimmun , vol.51 , pp. 30-37
    • Lahiri, A.1
  • 78
    • 0035175146 scopus 로고    scopus 로고
    • Synthesis and release of B lymphocyte stimulator from myeloid cells
    • Nardelli, B. et al. Synthesis and release of B lymphocyte stimulator from myeloid cells. Blood 97, 198-204 (2001)
    • (2001) Blood , vol.97 , pp. 198-204
    • Nardelli, B.1
  • 79
    • 0036732753 scopus 로고    scopus 로고
    • DCs induce CD40 independent immunoglobulin class switching through BLyS and April
    • Litinskiy, M. B. et al. DCs induce CD40 independent immunoglobulin class switching through BLyS and APRIL. Nat. Immunol. 3, 822-829 (2002)
    • (2002) Nat. Immunol , vol.3 , pp. 822-829
    • Litinskiy, M.B.1
  • 80
    • 84953210532 scopus 로고    scopus 로고
    • The expression of BAFF is controlled by IRF transcription factors
    • Sjostrand, M. et al. The expression of BAFF is controlled by IRF transcription factors. J. Immunol. 196, 91-96 (2016)
    • (2016) J. Immunol , vol.196 , pp. 91-96
    • Sjostrand, M.1
  • 81
    • 84875958991 scopus 로고    scopus 로고
    • Prevalence of interferon type i signature in CD14 monocytes of patients with Sjogren's syndrome and association with disease activity and BAFF gene expression
    • Brkic, Z. et al. Prevalence of interferon type I signature in CD14 monocytes of patients with Sjogren's syndrome and association with disease activity and BAFF gene expression. Ann. Rheum. Dis. 72, 728-735 (2013)
    • (2013) Ann. Rheum. Dis , vol.72 , pp. 728-735
    • Brkic, Z.1
  • 82
    • 44849084239 scopus 로고    scopus 로고
    • Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR-and type i IFN-dependent and-independent pathways
    • Ittah, M. et al. Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR-and type I IFN-dependent and-independent pathways. Eur. J. Immunol. 38, 1058-1064 (2008)
    • (2008) Eur. J. Immunol , vol.38 , pp. 1058-1064
    • Ittah, M.1
  • 83
    • 79952009770 scopus 로고    scopus 로고
    • Induction of B cell-activating factor by viral infection is a general phenomenon, but the types of viruses and mechanisms depend on cell type
    • Ittah, M. et al. Induction of B cell-activating factor by viral infection is a general phenomenon, but the types of viruses and mechanisms depend on cell type. J. Innate Immun. 3, 200-207 (2011)
    • (2011) J. Innate Immun , vol.3 , pp. 200-207
    • Ittah, M.1
  • 84
    • 0036144353 scopus 로고    scopus 로고
    • Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
    • Groom, J. et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome. J. Clin. Invest. 109, 59-68 (2002)
    • (2002) J. Clin. Invest , vol.109 , pp. 59-68
    • Groom, J.1
  • 85
    • 84979031446 scopus 로고    scopus 로고
    • BAFF overexpression increases lymphocytic infiltration in Sjogren's target tissue, but only inefficiently promotes ectopic B cell differentiation
    • Ding, J. et al. BAFF overexpression increases lymphocytic infiltration in Sjogren's target tissue, but only inefficiently promotes ectopic B cell differentiation. Clin. Immunol. 169, 69-79 (2016)
    • (2016) Clin. Immunol , vol.169 , pp. 69-79
    • Ding, J.1
  • 86
    • 84866534641 scopus 로고    scopus 로고
    • Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice
    • Bombardieri, M. et al. Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice. J. Immunol. 189, 3767-3776 (2012)
    • (2012) J. Immunol , vol.189 , pp. 3767-3776
    • Bombardieri, M.1
  • 87
    • 0242663585 scopus 로고    scopus 로고
    • Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjogren's syndrome
    • Salomonsson, S. et al. Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjogren's syndrome. Arthritis Rheum. 48, 3187-3201 (2003)
    • (2003) Arthritis Rheum , vol.48 , pp. 3187-3201
    • Salomonsson, S.1
  • 88
    • 65449138304 scopus 로고    scopus 로고
    • Ectopic germinal centers are rare in Sjogren's syndrome salivary glands and do not exclude autoreactive B cells
    • Pottier, L. et al. Ectopic germinal centers are rare in Sjogren's syndrome salivary glands and do not exclude autoreactive B cells. J. Immunol. 182, 3540-3547 (2009)
    • (2009) J. Immunol , vol.182 , pp. 3540-3547
    • Pottier, L.1
  • 89
    • 85012920165 scopus 로고    scopus 로고
    • Ectopic lymphoid neogenesis in rheumatic autoimmune diseases
    • Bombardieri, M., Lewis, M. &Pitzalis, C. Ectopic lymphoid neogenesis in rheumatic autoimmune diseases. Nat. Rev. Rheumatol. 13, 141-154 (2017)
    • (2017) Nat. Rev. Rheumatol , vol.13 , pp. 141-154
    • Bombardieri, M.1    Lewis, M.2    Pitzalis, C.3
  • 90
    • 0030582773 scopus 로고    scopus 로고
    • A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
    • Forster, R. et al. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87, 1037-1047 (1996)
    • (1996) Cell , vol.87 , pp. 1037-1047
    • Forster, R.1
  • 91
    • 0033679060 scopus 로고    scopus 로고
    • BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis
    • Luther, S. A., Lopez, T., Bai, W., Hanahan, D. &Cyster, J. G. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis. Immunity 12, 471-481 (2000)
    • (2000) Immunity , vol.12 , pp. 471-481
    • Luther, S.A.1    Lopez, T.2    Bai, W.3    Hanahan, D.4    Cyster, J.G.5
  • 92
    • 84948417390 scopus 로고    scopus 로고
    • CXCL13 and CCL11 serum levels and lymphoma and disease activity in primary Sjogren's syndrome
    • Nocturne, G. et al. CXCL13 and CCL11 serum levels and lymphoma and disease activity in primary Sjogren's syndrome. Arthritis Rheumatol. 67, 3226-3233 (2015)
    • (2015) Arthritis Rheumatol , vol.67 , pp. 3226-3233
    • Nocturne, G.1
  • 93
    • 44449140526 scopus 로고    scopus 로고
    • CXCL13, CCL21, and CXCL12 expression in salivary glands of patients with Sjogren's syndrome and MALT lymphoma: Association with reactive and malignant areas of lymphoid organization
    • Barone, F. et al. CXCL13, CCL21, and CXCL12 expression in salivary glands of patients with Sjogren's syndrome and MALT lymphoma: association with reactive and malignant areas of lymphoid organization. J. Immunol. 180, 5130-5140 (2008)
    • (2008) J. Immunol , vol.180 , pp. 5130-5140
    • Barone, F.1
  • 94
    • 84940979239 scopus 로고    scopus 로고
    • IL 22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs
    • Barone, F. et al. IL 22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs. Proc. Natl Acad. Sci. USA 112, 11024-11029 (2015)
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 11024-11029
    • Barone, F.1
  • 95
    • 84855350256 scopus 로고    scopus 로고
    • Potential involvement of IL 22 and IL 22 producing cells in the inflamed salivary glands of patients with Sjogren's syndrome
    • Ciccia, F. et al. Potential involvement of IL 22 and IL 22 producing cells in the inflamed salivary glands of patients with Sjogren's syndrome. Ann. Rheum. Dis. 71, 295-301 (2012)
    • (2012) Ann. Rheum. Dis , vol.71 , pp. 295-301
    • Ciccia, F.1
  • 96
    • 77954627022 scopus 로고    scopus 로고
    • Expansion of human NK 22 cells with IL 7, IL 2, and IL 1ß reveals intrinsic functional plasticity
    • Cella, M., Otero, K. &Colonna, M. Expansion of human NK 22 cells with IL 7, IL 2, and IL 1ß reveals intrinsic functional plasticity. Proc. Natl Acad. Sci. USA 107, 10961-10966 (2010)
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 10961-10966
    • Cella, M.1    Otero, K.2    Colonna, M.3
  • 97
    • 84948070672 scopus 로고    scopus 로고
    • Interleukin (IL)-22 receptor 1 is overexpressed in primary Sjogren's syndrome and Sjogren-associated non-Hodgkin lymphomas and is regulated by IL 18
    • Ciccia, F. et al. Interleukin (IL)-22 receptor 1 is overexpressed in primary Sjogren's syndrome and Sjogren-associated non-Hodgkin lymphomas and is regulated by IL 18. Clin. Exp. Immunol. 181, 219-229 (2015)
    • (2015) Clin. Exp. Immunol , vol.181 , pp. 219-229
    • Ciccia, F.1
  • 98
    • 84855445128 scopus 로고    scopus 로고
    • Impact of interleukin 21 in the pathogenesis of primary Sjogren's syndrome: Increased serum levels of interleukin 21 and its expression in the labial salivary glands
    • Kang, K. Y. et al. Impact of interleukin 21 in the pathogenesis of primary Sjogren's syndrome: increased serum levels of interleukin 21 and its expression in the labial salivary glands. Arthritis Res. Ther. 13, R179 (2011)
    • (2011) Arthritis Res. Ther , vol.13 , pp. R179
    • Kang, K.Y.1
  • 99
    • 84863605611 scopus 로고    scopus 로고
    • Selective localization of T helper subsets in labial salivary glands from primary Sjogren's syndrome patients
    • Maehara, T. et al. Selective localization of T helper subsets in labial salivary glands from primary Sjogren's syndrome patients. Clin. Exp. Immunol. 169, 89-99 (2012)
    • (2012) Clin. Exp. Immunol , vol.169 , pp. 89-99
    • Maehara, T.1
  • 100
    • 84901264968 scopus 로고    scopus 로고
    • Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjogren's syndrome
    • Gong, Y. Z. et al. Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjogren's syndrome. J. Autoimmun. 51, 57-66 (2014)
    • (2014) J. Autoimmun , vol.51 , pp. 57-66
    • Gong, Y.Z.1
  • 101
    • 85028538858 scopus 로고    scopus 로고
    • Elevated CCL25 and CCR9 expressing T helper cells in salivary glands of primary Sjogren's syndrome patients: Potential new axis in lymphoid neogenesis
    • Blokland, S. L. M. et al. Elevated CCL25 and CCR9 expressing T helper cells in salivary glands of primary Sjogren's syndrome patients: potential new axis in lymphoid neogenesis. Arthritis Rheumatol. 69, 2038-2051 (2017)
    • (2017) Arthritis Rheumatol , vol.69 , pp. 2038-2051
    • Blokland, S.L.M.1
  • 102
    • 85011994125 scopus 로고    scopus 로고
    • Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
    • Rao, D. A. et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature 542, 110-114 (2017)
    • (2017) Nature , vol.542 , pp. 110-114
    • Rao, D.A.1
  • 103
    • 85028446601 scopus 로고    scopus 로고
    • Attenuation of follicular helper T cell-dependent B cell hyperactivity by abatacept treatment in primary Sjogren's syndrome
    • Verstappen, G. M. et al. Attenuation of follicular helper T cell-dependent B cell hyperactivity by abatacept treatment in primary Sjogren's syndrome. Arthritis Rheumatol. 69, 1850-1861 (2017)
    • (2017) Arthritis Rheumatol , vol.69 , pp. 1850-1861
    • Verstappen, G.M.1
  • 104
    • 84922032744 scopus 로고    scopus 로고
    • Re thinking the functions of IgA(+) plasma cells
    • Gommerman, J. L., Rojas, O. L. &Fritz, J. H. Re thinking the functions of IgA(+) plasma cells. Gut Microbes 5, 652-662 (2014)
    • (2014) Gut Microbes , vol.5 , pp. 652-662
    • Gommerman, J.L.1    Rojas, O.L.2    Fritz, J.H.3
  • 105
    • 78650945786 scopus 로고    scopus 로고
    • Salivary glands of primary Sjogren's syndrome patients express factors vital for plasma cell survival
    • Szyszko, E. A. et al. Salivary glands of primary Sjogren's syndrome patients express factors vital for plasma cell survival. Arthritis Res. Ther. 13, R2 (2011)
    • (2011) Arthritis Res. Ther , vol.13 , pp. R2
    • Szyszko, E.A.1
  • 106
    • 84994494311 scopus 로고    scopus 로고
    • 2016 American college of rheumatology/european league against rheumatism classification criteria for primary sjogren's syndrome: A consensus and data-driven methodology involving three international patient cohorts
    • Shiboski, C. H. et al. 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjogren's syndrome: a consensus and data-driven methodology involving three international patient cohorts. Ann. Rheum. Dis. 76, 9-16 (2017)
    • (2017) Ann. Rheum. Dis , vol.76 , pp. 9-16
    • Shiboski, C.H.1
  • 107
    • 33748320925 scopus 로고    scopus 로고
    • Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and-SSB/La antibodies in the pathogenesis of congenital heart block
    • Clancy, R. M. et al. Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and-SSB/La antibodies in the pathogenesis of congenital heart block. J. Clin. Invest. 116, 2413-2422 (2006)
    • (2006) J. Clin. Invest , vol.116 , pp. 2413-2422
    • Clancy, R.M.1
  • 108
    • 84868246211 scopus 로고    scopus 로고
    • Novel autoantibodies in Sjogren's syndrome
    • Shen, L. et al. Novel autoantibodies in Sjogren's syndrome. Clin. Immunol. 145, 251-255 (2012)
    • (2012) Clin. Immunol , vol.145 , pp. 251-255
    • Shen, L.1
  • 109
    • 84957111372 scopus 로고    scopus 로고
    • Association of antibodies to interferoninducible protein 16 with markers of more severe disease in primary Sjogren's syndrome
    • Baer, A. N., Petri, M., Sohn, J., Rosen, A. &Casciola-Rosen, L. Association of antibodies to interferoninducible protein 16 with markers of more severe disease in primary Sjogren's syndrome. Arthritis Care Res. 68, 254-260 (2016)
    • (2016) Arthritis Care Res , vol.68 , pp. 254-260
    • Baer, A.N.1    Petri, M.2    Sohn, J.3    Rosen, A.4    Casciola-Rosen, L.5
  • 110
    • 0037061453 scopus 로고    scopus 로고
    • Chromatin-IgG complexes activate B cells by dual engagement of IgM and Tolllike receptors
    • Leadbetter, E. A. et al. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Tolllike receptors. Nature 416, 603-607 (2002)
    • (2002) Nature , vol.416 , pp. 603-607
    • Leadbetter, E.A.1
  • 111
    • 80155173180 scopus 로고    scopus 로고
    • Molecular signature of a public clonotypic autoantibody in primary Sjogren's syndrome: A 'forbidden' clone in systemic autoimmunity
    • Lindop, R. et al. Molecular signature of a public clonotypic autoantibody in primary Sjogren's syndrome: a 'forbidden' clone in systemic autoimmunity. Arthritis Rheum. 63, 3477-3486 (2011)
    • (2011) Arthritis Rheum , vol.63 , pp. 3477-3486
    • Lindop, R.1
  • 112
    • 84885114650 scopus 로고    scopus 로고
    • An immunodominant La/SSB autoantibody proteome derives from public clonotypes
    • Thurgood, L. A. et al. An immunodominant La/SSB autoantibody proteome derives from public clonotypes. Clin. Exp. Immunol. 174, 237-244 (2013)
    • (2013) Clin. Exp. Immunol , vol.174 , pp. 237-244
    • Thurgood, L.A.1
  • 113
    • 33744503669 scopus 로고    scopus 로고
    • Lymphoma and other malignancies in primary Sjogren's syndrome: A cohort study on cancer incidence and lymphoma predictors
    • Theander, E. et al. Lymphoma and other malignancies in primary Sjogren's syndrome: a cohort study on cancer incidence and lymphoma predictors. Ann. Rheum. Dis. 65, 796-803 (2006)
    • (2006) Ann. Rheum. Dis , vol.65 , pp. 796-803
    • Theander, E.1
  • 114
    • 30344479938 scopus 로고    scopus 로고
    • Autoimmune and chronic inflammatory disorders and risk of non-Hodgkin lymphoma by subtype
    • Smedby, K. E. et al. Autoimmune and chronic inflammatory disorders and risk of non-Hodgkin lymphoma by subtype. J. Natl Cancer Inst. 98, 51-60 (2006)
    • (2006) J. Natl Cancer Inst , vol.98 , pp. 51-60
    • Smedby, K.E.1
  • 115
    • 84857913542 scopus 로고    scopus 로고
    • Incidence of cancer in a nationwide population cohort of 7852 patients with primary Sjogren's syndrome in Taiwan
    • Weng, M. Y., Huang, Y. T., Liu, M. F. &Lu, T. H. Incidence of cancer in a nationwide population cohort of 7852 patients with primary Sjogren's syndrome in Taiwan. Ann. Rheum. Dis. 71, 524-527 (2012)
    • (2012) Ann. Rheum. Dis , vol.71 , pp. 524-527
    • Weng, M.Y.1    Huang, Y.T.2    Liu, M.F.3    Lu, T.H.4
  • 116
    • 84876708705 scopus 로고    scopus 로고
    • Risk of non-Hodgkin's lymphoma in primary Sjogren's syndrome: A population-based study
    • Johnsen, S. J. et al. Risk of non-Hodgkin's lymphoma in primary Sjogren's syndrome: a population-based study. Arthritis Care Res. 65, 816-821 (2013)
    • (2013) Arthritis Care Res , vol.65 , pp. 816-821
    • Johnsen, S.J.1
  • 117
    • 0033865077 scopus 로고    scopus 로고
    • Salivary gland lymphomas in patients with Sjogren's syndrome may frequently develop from rheumatoid factor B cells
    • Martin, T. et al. Salivary gland lymphomas in patients with Sjogren's syndrome may frequently develop from rheumatoid factor B cells. Arthritis Rheum. 43, 908-916 (2000)
    • (2000) Arthritis Rheum , vol.43 , pp. 908-916
    • Martin, T.1
  • 118
    • 18244385722 scopus 로고    scopus 로고
    • Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity
    • Bende, R. J. et al. Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity. J. Exp. Med. 201, 1229-1241 (2005)
    • (2005) J. Exp. Med , vol.201 , pp. 1229-1241
    • Bende, R.J.1
  • 119
    • 84865134897 scopus 로고    scopus 로고
    • C X C chemokine receptor type 5 gene polymorphisms are associated with non-Hodgkin lymphoma
    • Song, H., Tong, D., Cha, Z. &Bai, J. C X C chemokine receptor type 5 gene polymorphisms are associated with non-Hodgkin lymphoma. Mol. Biol. Rep. 39, 8629-8635 (2012)
    • (2012) Mol. Biol. Rep , vol.39 , pp. 8629-8635
    • Song, H.1    Tong, D.2    Cha, Z.3    Bai, J.4
  • 120
    • 79959799977 scopus 로고    scopus 로고
    • Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjogren's syndrome
    • Theander, E. et al. Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjogren's syndrome. Ann. Rheum. Dis. 70, 1363-1368 (2011)
    • (2011) Ann. Rheum. Dis , vol.70 , pp. 1363-1368
    • Theander, E.1
  • 121
    • 84903881565 scopus 로고    scopus 로고
    • The prognostic value of routinely performed minor salivary gland assessments in primary Sjogren's syndrome
    • Risselada, A. P. et al. The prognostic value of routinely performed minor salivary gland assessments in primary Sjogren's syndrome. Ann. Rheum. Dis. 73, 1537-1540 (2014)
    • (2014) Ann. Rheum. Dis , vol.73 , pp. 1537-1540
    • Risselada, A.P.1
  • 122
    • 85030618443 scopus 로고    scopus 로고
    • Germinal centres in diagnostic labial gland biopsies of patients with primary Sjogren's syndrome are not predictive for parotid MALT lymphoma development
    • Haacke, E. A. et al. Germinal centres in diagnostic labial gland biopsies of patients with primary Sjogren's syndrome are not predictive for parotid MALT lymphoma development. Ann. Rheum. Dis. 76, 1781-1784 (2017)
    • (2017) Ann. Rheum. Dis , vol.76 , pp. 1781-1784
    • Haacke, E.A.1
  • 123
    • 84875684077 scopus 로고    scopus 로고
    • BLyS upregulation in Sjogren's syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B cell clonal expansion in the salivary glands
    • Quartuccio, L. et al. BLyS upregulation in Sjogren's syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B cell clonal expansion in the salivary glands. Rheumatology 52, 276-281 (2013)
    • (2013) Rheumatology , vol.52 , pp. 276-281
    • Quartuccio, L.1
  • 124
    • 85018305337 scopus 로고    scopus 로고
    • Overexpression of the cytokine BAFF and autoimmunity risk
    • Steri, M. et al. Overexpression of the cytokine BAFF and autoimmunity risk. N. Engl. J. Med. 376, 1615-1626 (2017)
    • (2017) N. Engl. J. Med , vol.376 , pp. 1615-1626
    • Steri, M.1
  • 125
    • 34247550864 scopus 로고    scopus 로고
    • No evidence for an association between the-871 T/C promoter polymorphism in the B cell-activating factor gene and primary Sjogren's syndrome
    • Gottenberg, J. E. et al. No evidence for an association between the-871 T/C promoter polymorphism in the B cell-activating factor gene and primary Sjogren's syndrome. Arthritis Res. Ther. 8, R30 (2006)
    • (2006) Arthritis Res. Ther , vol.8 , pp. R30
    • Gottenberg, J.E.1
  • 126
    • 84901271891 scopus 로고    scopus 로고
    • B Cell activating factor genetic variants in lymphomagenesis associated with primary Sjogren's syndrome
    • Nezos, A. et al. B Cell activating factor genetic variants in lymphomagenesis associated with primary Sjogren's syndrome. J. Autoimmun. 51, 89-98 (2014)
    • (2014) J. Autoimmun , vol.51 , pp. 89-98
    • Nezos, A.1
  • 127
    • 66249083857 scopus 로고    scopus 로고
    • Genetic variation in B cell-activating factor is associated with an increased risk of developing B cell non-Hodgkin lymphoma
    • Novak, A. J. et al. Genetic variation in B cell-activating factor is associated with an increased risk of developing B cell non-Hodgkin lymphoma. Cancer Res. 69, 4217-4224 (2009)
    • (2009) Cancer Res , vol.69 , pp. 4217-4224
    • Novak, A.J.1
  • 128
    • 84988864510 scopus 로고    scopus 로고
    • A BAFF receptor His159Tyr mutation in Sjogren's syndrome-related lymphoproliferation
    • Papageorgiou, A. et al. A BAFF receptor His159Tyr mutation in Sjogren's syndrome-related lymphoproliferation. Arthritis Rheumatol. 67, 2732-2741 (2015)
    • (2015) Arthritis Rheumatol , vol.67 , pp. 2732-2741
    • Papageorgiou, A.1
  • 129
    • 78249275244 scopus 로고    scopus 로고
    • The Fms-like tyrosine kinase 3 ligand, a mediator of B cell survival, is also a marker of lymphoma in primary Sjogren's syndrome
    • Tobon, G. J. et al. The Fms-like tyrosine kinase 3 ligand, a mediator of B cell survival, is also a marker of lymphoma in primary Sjogren's syndrome. Arthritis Rheum. 62, 3447-3456 (2010)
    • (2010) Arthritis Rheum , vol.62 , pp. 3447-3456
    • Tobon, G.J.1
  • 130
    • 79960246157 scopus 로고    scopus 로고
    • A failure of TNFAIP3 negative regulation maintains sustained NF kB activation in Sjogren's syndrome
    • Sisto, M. et al. A failure of TNFAIP3 negative regulation maintains sustained NF kB activation in Sjogren's syndrome. Histochem. Cell Biol. 135, 615-625 (2011)
    • (2011) Histochem. Cell Biol , vol.135 , pp. 615-625
    • Sisto, M.1
  • 131
    • 84960082055 scopus 로고    scopus 로고
    • Low protein A20 in minor salivary glands is associated with lymphoma in primary Sjogren's syndrome
    • Johnsen, S. J. et al. Low protein A20 in minor salivary glands is associated with lymphoma in primary Sjogren's syndrome. Scand. J. Immunol. 83, 181-187 (2016)
    • (2016) Scand. J. Immunol , vol.83 , pp. 181-187
    • Johnsen, S.J.1
  • 132
    • 79955471681 scopus 로고    scopus 로고
    • Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases
    • Musone, S. L. et al. Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases. Genes Immun. 12, 176-182 (2011)
    • (2011) Genes Immun , vol.12 , pp. 176-182
    • Musone, S.L.1
  • 133
    • 54349116244 scopus 로고    scopus 로고
    • Reduction of fatigue in Sjogren syndrome with rituximab: Results of a randomised, double-blind, placebo-controlled pilot study
    • Dass, S. et al. Reduction of fatigue in Sjogren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study. Ann. Rheum. Dis. 67, 1541-1544 (2008)
    • (2008) Ann. Rheum. Dis , vol.67 , pp. 1541-1544
    • Dass, S.1
  • 134
    • 77950538947 scopus 로고    scopus 로고
    • Effectiveness of rituximab treatment in primary Sjogren's syndrome: A randomized, double-blind, placebo-controlled trial
    • Meijer, J. M. et al. Effectiveness of rituximab treatment in primary Sjogren's syndrome: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 62, 960-968 (2010)
    • (2010) Arthritis Rheum , vol.62 , pp. 960-968
    • Meijer, J.M.1
  • 135
    • 84894243056 scopus 로고    scopus 로고
    • Treatment of primary Sjogren syndrome with rituximab: A randomized trial
    • Devauchelle-Pensec, V. et al. Treatment of primary Sjogren syndrome with rituximab: a randomized trial. Ann. Intern. Med. 160, 233-242 (2014)
    • (2014) Ann. Intern. Med , vol.160 , pp. 233-242
    • Devauchelle-Pensec, V.1
  • 136
    • 85020237160 scopus 로고    scopus 로고
    • Randomized controlled trial of rituximab and cost-effectiveness analysis in treating fatigue and oral dryness in primary Sjogren's syndrome
    • Bowman, S. J. et al. Randomized controlled trial of rituximab and cost-effectiveness analysis in treating fatigue and oral dryness in primary Sjogren's syndrome. Arthritis Rheumatol. 69, 1440-1450 (2017)
    • (2017) Arthritis Rheumatol , vol.69 , pp. 1440-1450
    • Bowman, S.J.1
  • 137
    • 85020307337 scopus 로고    scopus 로고
    • Rituximab in the treatment of Sjogren's syndrome: Is it the right or wrong drug?
    • Bootsma, H., Kroese, F. G. M. &Vissink, A. Rituximab in the treatment of Sjogren's syndrome: Is it the right or wrong drug? Arthritis Rheumatol. 69, 1346-1349 (2017)
    • (2017) Arthritis Rheumatol , vol.69 , pp. 1346-1349
    • Bootsma, H.1    Kroese, F.G.M.2    Vissink, A.3
  • 138
    • 84877611272 scopus 로고    scopus 로고
    • Efficacy of rituximab in systemic manifestations of primary Sjogren's syndrome: Results in 78 patients of the AutoImmune and Rituximab registry
    • Gottenberg, J. E. et al. Efficacy of rituximab in systemic manifestations of primary Sjogren's syndrome: results in 78 patients of the AutoImmune and Rituximab registry. Ann. Rheum. Dis. 72, 1026-1031 (2013)
    • (2013) Ann. Rheum. Dis , vol.72 , pp. 1026-1031
    • Gottenberg, J.E.1
  • 139
    • 84922391089 scopus 로고    scopus 로고
    • Efficacy and safety of belimumab in primary Sjogren's syndrome: Results of the BELISS open-label phase II study
    • Mariette, X. et al. Efficacy and safety of belimumab in primary Sjogren's syndrome: results of the BELISS open-label phase II study. Ann. Rheum. Dis. 74, 526-531 (2015)
    • (2015) Ann. Rheum. Dis , vol.74 , pp. 526-531
    • Mariette, X.1
  • 140
    • 34047177483 scopus 로고    scopus 로고
    • Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjogren's syndrome
    • Seror, R. et al. Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjogren's syndrome. Ann. Rheum. Dis. 66, 351-357 (2007)
    • (2007) Ann. Rheum. Dis , vol.66 , pp. 351-357
    • Seror, R.1
  • 141
    • 84871038633 scopus 로고    scopus 로고
    • Serum levels of BAFF, but not April, are increased after rituximab treatment in patients with primary Sjogren's syndrome: Data from a placebo-controlled clinical trial
    • Pollard, R. P. E. et al. Serum levels of BAFF, but not APRIL, are increased after rituximab treatment in patients with primary Sjogren's syndrome: data from a placebo-controlled clinical trial. Ann. Rheum. Dis. 72, 146-148 (2013)
    • (2013) Ann. Rheum. Dis , vol.72 , pp. 146-148
    • Pollard, R.P.E.1
  • 142
    • 34247613820 scopus 로고    scopus 로고
    • Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: Insights into a new regulating system of BAFF production
    • Lavie, F. et al. Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: insights into a new regulating system of BAFF production. Ann. Rheum. Dis. 66, 700-703 (2007)
    • (2007) Ann. Rheum. Dis , vol.66 , pp. 700-703
    • Lavie, F.1
  • 143
    • 84957429265 scopus 로고    scopus 로고
    • Blood and salivary-gland BAFF-driven B cell hyperactivity is associated to rituximab inefficacy in primary Sjogren's syndrome
    • Cornec, D. et al. Blood and salivary-gland BAFF-driven B cell hyperactivity is associated to rituximab inefficacy in primary Sjogren's syndrome. J. Autoimmun. 67, 102-110 (2016)
    • (2016) J. Autoimmun , vol.67 , pp. 102-110
    • Cornec, D.1
  • 144
    • 34248597383 scopus 로고    scopus 로고
    • BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjogren's syndrome
    • Pers, J. O. et al. BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjogren's syndrome. Arthritis Rheum. 56, 1464-1477 (2007)
    • (2007) Arthritis Rheum , vol.56 , pp. 1464-1477
    • Pers, J.O.1
  • 145
    • 85041107527 scopus 로고    scopus 로고
    • Efficacy and safety of atacicept in patients with systemic lupus erythematosus: Results of a 24 week randomized, placebo-controlled, phase IIb study
    • Merrill, J. T. et al. Efficacy and safety of atacicept in patients with systemic lupus erythematosus: results of a 24 week randomized, placebo-controlled, phase IIb study. Arthritis Rheumatol. https://doi.org/10.1002/ art.40360 (2017)
    • (2017) Arthritis Rheumatol
    • Merrill, J.T.1
  • 146
    • 84934975828 scopus 로고    scopus 로고
    • The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus
    • Alexander, T. et al. The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus. Ann. Rheum. Dis. 74, 1474-1478 (2015)
    • (2015) Ann. Rheum. Dis , vol.74 , pp. 1474-1478
    • Alexander, T.1
  • 147
    • 84942436321 scopus 로고    scopus 로고
    • Targeting CD38 with daratumumab monotherapy in multiple myeloma
    • Lokhorst, H. M. et al. Targeting CD38 with daratumumab monotherapy in multiple myeloma. N. Engl. J. Med. 373, 1207-1219 (2015)
    • (2015) N. Engl. J. Med , vol.373 , pp. 1207-1219
    • Lokhorst, H.M.1
  • 148
    • 84945936980 scopus 로고    scopus 로고
    • The expanding family of regulatory B cells
    • Mauri, C. &Menon, M. The expanding family of regulatory B cells. Int. Immunol. 27, 479-486 (2015)
    • (2015) Int. Immunol , vol.27 , pp. 479-486
    • Mauri, C.1    Menon, M.2
  • 149
    • 84873601139 scopus 로고    scopus 로고
    • IL 10 producing regulatory B cells (B10 cells) in autoimmune disease
    • Kalampokis, I., Yoshizaki, A. &Tedder, T. F. IL 10 producing regulatory B cells (B10 cells) in autoimmune disease. Arthritis Res. Ther. 15 (Suppl. 1), S1 (2013)
    • (2013) Arthritis Res. Ther , vol.15 , Issue.1 , pp. S1
    • Kalampokis, I.1    Yoshizaki, A.2    Tedder, T.F.3
  • 150
    • 2942755979 scopus 로고    scopus 로고
    • T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non Th1/Th2 effector cells that provide help for B cells
    • Chtanova, T. et al. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non Th1/Th2 effector cells that provide help for B cells. J. Immunol. 173, 68-78 (2004)
    • (2004) J. Immunol , vol.173 , pp. 68-78
    • Chtanova, T.1
  • 151
    • 85017940817 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT02291029 (2017)
    • (2017) US National Library of Medicine
  • 152
    • 85017940817 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT02334306 (2017)
    • (2017) US National Library of Medicine
  • 153
    • 84908157888 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT01782235 (2014)
    • (2014) US National Library of Medicine
  • 154
    • 85017940817 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT02149420 (2017)
    • (2017) US National Library of Medicine
  • 155
    • 85017940817 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT02610543 (2017)
    • (2017) US National Library of Medicine
  • 156
    • 85017940817 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT02631538 (2017)
    • (2017) US National Library of Medicine
  • 157
    • 84962251251 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT02067910 (2016)
    • (2016) US National Library of Medicine
  • 158
    • 85017940817 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT02915159 (2017)
    • (2017) US National Library of Medicine
  • 159
    • 85017940817 scopus 로고    scopus 로고
    • US National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT02780674 (2017)
    • (2017) US National Library of Medicine


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.