Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 37, 2015, Pages 11612-11617

  Minamitani, Takeharu ^a   Yasui, Teruhito ^a   Ma, Yijie ^b   Zhou, Hufeng ^b   Okuzaki, Daisuke ^a   Tsai, Chiau Yuang ^a   Sakakibara, Shuhei ^a   Gewurz, Benjamin E ^b   Kieff, Elliott ^b   Kikutani, Hitoshi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Autoimmune diseases; B cells; Germinal center; LMP2A; Plasma cell differentiation

Indexed keywords

B CELL ANTIGEN RECEPTOR; B LYMPHOCYTE ANTIGEN; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; B LYMPHOCYTE RECEPTOR; INTERFERON REGULATORY FACTOR 4; LATENT MEMBRANE PROTEIN 2; LATENT MEMBRANE PROTEIN 2A; LYMPHOCYTE ANTIGEN RECEPTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; AUTOANTIBODY; EBV-ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN-BARR VIRUS; GREEN FLUORESCENT PROTEIN; MATRIX PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE ACTIVATION; B LYMPHOCYTE DIFFERENTIATION; CELL EXPANSION; CELL LINEAGE; CELL SELECTION; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSPOT ASSAY; EPIGENETICS; EPSTEIN BARR VIRUS; EPSTEIN BARR VIRUS INFECTION; FLOW CYTOMETRY; GENE LOCUS; GERMINAL CENTER; GLOMERULONEPHRITIS; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IN VITRO STUDY; IN VIVO STUDY; INTERNAL RIBOSOME ENTRY SITE; LYMPHOCYTE PROLIFERATION; MEMORY CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERSISTENT INFECTION; PHENOTYPE; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOP CODON; SYSTEMIC LUPUS ERYTHEMATOSUS; ANIMAL; AUTOIMMUNE DISEASE; BAGG ALBINO MOUSE; C57BL MOUSE; CELL DIFFERENTIATION; CHEMISTRY; CROSS BREEDING; CYTOLOGY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; HETEROZYGOTE; METABOLISM; SPLEEN; VIROLOGY;

ANIMALS; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CELL DIFFERENTIATION; CELL LINEAGE; CROSSES, GENETIC; EPIGENESIS, GENETIC; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GERMINAL CENTER; GREEN FLUORESCENT PROTEINS; HERPESVIRUS 4, HUMAN; HETEROZYGOTE; IMMUNITY, HUMORAL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; SPLEEN; VIRAL MATRIX PROTEINS; ZINC FINGERS;

EID: 84941703211     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1514484112     Document Type: Article

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