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Volumn 69, Issue 6, 2017, Pages 1313-1324

Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease

Author keywords

[No Author keywords available]

Indexed keywords

ABATACEPT; AUTOANTIBODY; B LYMPHOCYTE RECEPTOR; BRUTON TYROSINE KINASE; CD27 ANTIGEN; CHEMOKINE RECEPTOR CCR6; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M; PROTEIN ANTIBODY; RHEUMATOID FACTOR; AGAMMAGLOBULINAEMIA TYROSINE KINASE; PROTEIN TYROSINE KINASE;

EID: 85019157685     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.40059     Document Type: Article
Times cited : (90)

References (56)
  • 1
    • 84880854544 scopus 로고    scopus 로고
    • Aberrant B cell selection and activation in systemic lupus erythematosus
    • Kil LP, Hendriks RW. Aberrant B cell selection and activation in systemic lupus erythematosus. Int Rev Immunol 2013;32:445–70.
    • (2013) Int Rev Immunol , vol.32 , pp. 445-470
    • Kil, L.P.1    Hendriks, R.W.2
  • 3
    • 84940118840 scopus 로고    scopus 로고
    • Prediction of Sjögren's syndrome years before diagnosis and identification of patients with early onset and severe disease course by autoantibody profiling
    • Theander E, Jonsson R, Sjöström B, Brokstad K, Olsson P, Henriksson G. Prediction of Sjögren's syndrome years before diagnosis and identification of patients with early onset and severe disease course by autoantibody profiling. Arthritis Rheumatol 2015;67:2427–36.
    • (2015) Arthritis Rheumatol , vol.67 , pp. 2427-2436
    • Theander, E.1    Jonsson, R.2    Sjöström, B.3    Brokstad, K.4    Olsson, P.5    Henriksson, G.6
  • 4
    • 22544469987 scopus 로고    scopus 로고
    • Sjögren's syndrome
    • Fox RI. Sjögren's syndrome. Lancet 2005;366:321–31.
    • (2005) Lancet , vol.366 , pp. 321-331
    • Fox, R.I.1
  • 5
    • 0026499331 scopus 로고
    • Serum anti–SS-B/La and IgA rheumatoid factor are markers of salivary gland disease activity in primary Sjögren's syndrome
    • Atkinson JC, Travis WD, Slocum L, Ebbs WL, Fox PC. Serum anti–SS-B/La and IgA rheumatoid factor are markers of salivary gland disease activity in primary Sjögren's syndrome. Arthritis Rheum 1992;35:1368–72.
    • (1992) Arthritis Rheum , vol.35 , pp. 1368-1372
    • Atkinson, J.C.1    Travis, W.D.2    Slocum, L.3    Ebbs, W.L.4    Fox, P.C.5
  • 7
    • 84892496831 scopus 로고    scopus 로고
    • Systemic involvement in primary Sjögren's syndrome evaluated by the EULAR-SS disease activity index: analysis of 921 Spanish patients (GEAS-SS registry)
    • Ramos-Casals M, Brito-Zeron P, Solans R, Camps MT, Casanovas A, Sopena B, et al. Systemic involvement in primary Sjögren's syndrome evaluated by the EULAR-SS disease activity index: analysis of 921 Spanish patients (GEAS-SS registry). Rheumatology (Oxford) 2014;53:321–31.
    • (2014) Rheumatology (Oxford) , vol.53 , pp. 321-331
    • Ramos-Casals, M.1    Brito-Zeron, P.2    Solans, R.3    Camps, M.T.4    Casanovas, A.5    Sopena, B.6
  • 8
    • 84887116043 scopus 로고    scopus 로고
    • Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome
    • Lessard CJ, Li H, Adrianto I, Ice JA, Rasmussen A, Grundahl KM, et al. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. Nat Genet 2013;45:1284–92.
    • (2013) Nat Genet , vol.45 , pp. 1284-1292
    • Lessard, C.J.1    Li, H.2    Adrianto, I.3    Ice, J.A.4    Rasmussen, A.5    Grundahl, K.M.6
  • 9
    • 0036144353 scopus 로고    scopus 로고
    • Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome
    • Groom J, Kalled SL, Cutler AH, Olson C, Woodcock SA, Schneider P, et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. J Clin Invest 2002;109:59–68.
    • (2002) J Clin Invest , vol.109 , pp. 59-68
    • Groom, J.1    Kalled, S.L.2    Cutler, A.H.3    Olson, C.4    Woodcock, S.A.5    Schneider, P.6
  • 10
    • 84875549975 scopus 로고    scopus 로고
    • Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype
    • Baumjohann D, Preite S, Reboldi A, Ronchi F, Ansel KM, Lanzavecchia A, et al. Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype. Immunity 2013;38:596–605.
    • (2013) Immunity , vol.38 , pp. 596-605
    • Baumjohann, D.1    Preite, S.2    Reboldi, A.3    Ronchi, F.4    Ansel, K.M.5    Lanzavecchia, A.6
  • 11
    • 84933278364 scopus 로고    scopus 로고
    • Antibody-independent functions of B cells: a focus on cytokines
    • Shen P, Fillatreau S. Antibody-independent functions of B cells: a focus on cytokines. Nat Rev Immunol 2015;15:441–51.
    • (2015) Nat Rev Immunol , vol.15 , pp. 441-451
    • Shen, P.1    Fillatreau, S.2
  • 13
    • 58849136715 scopus 로고    scopus 로고
    • Treatment of primary Sjögren syndrome with rituximab: extended follow-up, safety and efficacy of retreatment
    • Meijer JM, Pijpe J, Vissink A, Kallenberg CG, Bootsma H. Treatment of primary Sjögren syndrome with rituximab: extended follow-up, safety and efficacy of retreatment. Ann Rheum Dis 2009;68:284–5.
    • (2009) Ann Rheum Dis , vol.68 , pp. 284-285
    • Meijer, J.M.1    Pijpe, J.2    Vissink, A.3    Kallenberg, C.G.4    Bootsma, H.5
  • 15
    • 79952070370 scopus 로고    scopus 로고
    • Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial
    • Navarra SV, Guzman RM, Gallacher AE, Hall S, Levy RA, Jimenez RE, et al. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial. Lancet 2011;377:721–31.
    • (2011) Lancet , vol.377 , pp. 721-731
    • Navarra, S.V.1    Guzman, R.M.2    Gallacher, A.E.3    Hall, S.4    Levy, R.A.5    Jimenez, R.E.6
  • 18
    • 84897055483 scopus 로고    scopus 로고
    • Targeting Bruton's tyrosine kinase in B cell malignancies
    • Hendriks RW, Yuvaraj S, Kil LP. Targeting Bruton's tyrosine kinase in B cell malignancies. Nat Rev Cancer 2014;14:219–32.
    • (2014) Nat Rev Cancer , vol.14 , pp. 219-232
    • Hendriks, R.W.1    Yuvaraj, S.2    Kil, L.P.3
  • 20
    • 77955625479 scopus 로고    scopus 로고
    • The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
    • Honigberg LA, Smith AM, Sirisawad M, Verner E, Loury D, Chang B, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A 2010;107:13075–80.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13075-13080
    • Honigberg, L.A.1    Smith, A.M.2    Sirisawad, M.3    Verner, E.4    Loury, D.5    Chang, B.6
  • 21
    • 84868470425 scopus 로고    scopus 로고
    • Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus
    • Hutcheson J, Vanarsa K, Bashmakov A, Grewal S, Sajitharan D, Chang BY, et al. Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus. Arthritis Res Ther 2012;14:R243.
    • (2012) Arthritis Res Ther , vol.14 , pp. R243
    • Hutcheson, J.1    Vanarsa, K.2    Bashmakov, A.3    Grewal, S.4    Sajitharan, D.5    Chang, B.Y.6
  • 22
    • 84883141402 scopus 로고    scopus 로고
    • Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase
    • Mina-Osorio P, LaStant J, Keirstead N, Whittard T, Ayala J, Stefanova S, et al. Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase. Arthritis Rheum 2013;65:2380–91.
    • (2013) Arthritis Rheum , vol.65 , pp. 2380-2391
    • Mina-Osorio, P.1    LaStant, J.2    Keirstead, N.3    Whittard, T.4    Ayala, J.5    Stefanova, S.6
  • 23
    • 84886074553 scopus 로고    scopus 로고
    • Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis
    • Rankin AL, Seth N, Keegan S, Andreyeva T, Cook TA, Edmonds J, et al. Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis. J Immunol 2013;191:4540–50.
    • (2013) J Immunol , vol.191 , pp. 4540-4550
    • Rankin, A.L.1    Seth, N.2    Keegan, S.3    Andreyeva, T.4    Cook, T.A.5    Edmonds, J.6
  • 24
    • 84863338029 scopus 로고    scopus 로고
    • RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents
    • Xu D, Kim Y, Postelnek J, Vu MD, Hu DQ, Liao C, et al. RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents. J Pharmacol Exp Ther 2012;341:90–103.
    • (2012) J Pharmacol Exp Ther , vol.341 , pp. 90-103
    • Xu, D.1    Kim, Y.2    Postelnek, J.3    Vu, M.D.4    Hu, D.Q.5    Liao, C.6
  • 25
    • 79960133279 scopus 로고    scopus 로고
    • The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
    • Chang BY, Huang MM, Francesco M, Chen J, Sokolove J, Magadala P, et al. The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells. Arthritis Res Ther 2011;13:R115.
    • (2011) Arthritis Res Ther , vol.13 , pp. R115
    • Chang, B.Y.1    Huang, M.M.2    Francesco, M.3    Chen, J.4    Sokolove, J.5    Magadala, P.6
  • 27
  • 28
    • 84860324857 scopus 로고    scopus 로고
    • Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice
    • Kil LP, de Bruijn MJ, van Nimwegen M, Corneth OB, van Hamburg JP, Dingjan GM, et al. Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice. Blood 2012;119:3744–56.
    • (2012) Blood , vol.119 , pp. 3744-3756
    • Kil, L.P.1    de Bruijn, M.J.2    van Nimwegen, M.3    Corneth, O.B.4    van Hamburg, J.P.5    Dingjan, G.M.6
  • 29
    • 78650196925 scopus 로고    scopus 로고
    • MicroRNAs prevent the generation of autoreactive antibodies
    • Belver L, de Yebenes VG, Ramiro AR. MicroRNAs prevent the generation of autoreactive antibodies. Immunity 2010;33:713–22.
    • (2010) Immunity , vol.33 , pp. 713-722
    • Belver, L.1    de Yebenes, V.G.2    Ramiro, A.R.3
  • 30
    • 47149085266 scopus 로고    scopus 로고
    • Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-κB
    • Yu L, Mohamed AJ, Simonson OE, Vargas L, Blomberg KE, Bjorkstrand B, et al. Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-κB. Blood 2008;111:4617–26.
    • (2008) Blood , vol.111 , pp. 4617-4626
    • Yu, L.1    Mohamed, A.J.2    Simonson, O.E.3    Vargas, L.4    Blomberg, K.E.5    Bjorkstrand, B.6
  • 32
    • 0031025342 scopus 로고    scopus 로고
    • Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region
    • Drabek D, Raguz S, de Wit TP, Dingjan GM, Savelkoul HF, Grosveld F, et al. Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region. Proc Natl Acad Sci U S A 1997;94:610–5.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 610-615
    • Drabek, D.1    Raguz, S.2    de Wit, T.P.3    Dingjan, G.M.4    Savelkoul, H.F.5    Grosveld, F.6
  • 33
    • 84975231564 scopus 로고    scopus 로고
    • Enhanced expression of Bruton's tyrosine kinase in B cells drives systemic autoimmunity by disrupting T cell homeostasis
    • Corneth OB, de Bruijn MJ, Rip J, Asmawidjaja PS, Kil LP, Hendriks RW. Enhanced expression of Bruton's tyrosine kinase in B cells drives systemic autoimmunity by disrupting T cell homeostasis. J Immunol 2016;197:58–67.
    • (2016) J Immunol , vol.197 , pp. 58-67
    • Corneth, O.B.1    de Bruijn, M.J.2    Rip, J.3    Asmawidjaja, P.S.4    Kil, L.P.5    Hendriks, R.W.6
  • 34
  • 36
    • 77956055481 scopus 로고    scopus 로고
    • 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative
    • Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO III, et al. 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 2010;62:2569–81.
    • (2010) Arthritis Rheum , vol.62 , pp. 2569-2581
    • Aletaha, D.1    Neogi, T.2    Silman, A.J.3    Funovits, J.4    Felson, D.T.5    Bingham, C.O.I.I.I.6
  • 37
    • 0036092482 scopus 로고    scopus 로고
    • Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group
    • Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, et al. Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 2002;61:554–8.
    • (2002) Ann Rheum Dis , vol.61 , pp. 554-558
    • Vitali, C.1    Bombardieri, S.2    Jonsson, R.3    Moutsopoulos, H.M.4    Alexander, E.L.5    Carsons, S.E.6
  • 38
    • 84902290218 scopus 로고    scopus 로고
    • Abatacept treatment reduces disease activity in early primary Sjögren's syndrome (open-label proof of concept ASAP study)
    • Meiners PM, Vissink A, Kroese FG, Spijkervet FK, Smitt-Kamminga NS, Abdulahad WH, et al. Abatacept treatment reduces disease activity in early primary Sjögren's syndrome (open-label proof of concept ASAP study). Ann Rheum Dis 2014;73:1393–6.
    • (2014) Ann Rheum Dis , vol.73 , pp. 1393-1396
    • Meiners, P.M.1    Vissink, A.2    Kroese, F.G.3    Spijkervet, F.K.4    Smitt-Kamminga, N.S.5    Abdulahad, W.H.6
  • 39
    • 84930181101 scopus 로고    scopus 로고
    • The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis
    • Paulissen SM, van Hamburg JP, Dankers W, Lubberts E. The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis. Cytokine 2015;74:43–53.
    • (2015) Cytokine , vol.74 , pp. 43-53
    • Paulissen, S.M.1    van Hamburg, J.P.2    Dankers, W.3    Lubberts, E.4
  • 40
    • 0036252104 scopus 로고    scopus 로고
    • Abnormal B cell differentiation in primary Sjögren's syndrome results in a depressed percentage of circulating memory B cells and elevated levels of soluble CD27 that correlate with Serum IgG concentration
    • Bohnhorst JO, Bjorgan MB, Thoen JE, Jonsson R, Natvig JB, Thompson KM. Abnormal B cell differentiation in primary Sjögren's syndrome results in a depressed percentage of circulating memory B cells and elevated levels of soluble CD27 that correlate with Serum IgG concentration. Clin Immunol 2002;103:79–88.
    • (2002) Clin Immunol , vol.103 , pp. 79-88
    • Bohnhorst, J.O.1    Bjorgan, M.B.2    Thoen, J.E.3    Jonsson, R.4    Natvig, J.B.5    Thompson, K.M.6
  • 41
    • 0036676086 scopus 로고    scopus 로고
    • Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjögren's syndrome
    • Hansen A, Odendahl M, Reiter K, Jacobi AM, Feist E, Scholze J, et al. Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjögren's syndrome. Arthritis Rheum 2002;46:2160–71.
    • (2002) Arthritis Rheum , vol.46 , pp. 2160-2171
    • Hansen, A.1    Odendahl, M.2    Reiter, K.3    Jacobi, A.M.4    Feist, E.5    Scholze, J.6
  • 42
    • 77952817885 scopus 로고    scopus 로고
    • Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients
    • Rodriguez-Bayona B, Ramos-Amaya A, Perez-Venegas JJ, Rodriguez C, Brieva JA. Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients. Arthritis Res Ther 2010;12:R108.
    • (2010) Arthritis Res Ther , vol.12 , pp. R108
    • Rodriguez-Bayona, B.1    Ramos-Amaya, A.2    Perez-Venegas, J.J.3    Rodriguez, C.4    Brieva, J.A.5
  • 43
    • 77953705028 scopus 로고    scopus 로고
    • on behalf of the EULAR Sjögren's Task Force. EULAR Sjögren's Syndrome Disease Activity Index: development of a consensus systemic disease activity index for primary Sjögren's syndrome
    • Seror R, Ravaud P, Bowman SJ, Baron G, Tzioufas A, Theander E, et al, on behalf of the EULAR Sjögren's Task Force. EULAR Sjögren's Syndrome Disease Activity Index: development of a consensus systemic disease activity index for primary Sjögren's syndrome. Ann Rheum Dis 2010;69:1103–9.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1103-1109
    • Seror, R.1    Ravaud, P.2    Bowman, S.J.3    Baron, G.4    Tzioufas, A.5    Theander, E.6
  • 44
    • 79955830742 scopus 로고    scopus 로고
    • EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjögren's syndrome
    • Seror R, Ravaud P, Mariette X, Bootsma H, Theander E, Hansen A, et al. EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjögren's syndrome. Ann Rheum Dis 2011;70:968–72.
    • (2011) Ann Rheum Dis , vol.70 , pp. 968-972
    • Seror, R.1    Ravaud, P.2    Mariette, X.3    Bootsma, H.4    Theander, E.5    Hansen, A.6
  • 45
    • 33845622856 scopus 로고    scopus 로고
    • Isotype distribution of anti–cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response
    • Verpoort KN, Jol-van der Zijde CM, Papendrecht-van der Voort EA, Ioan-Facsinay A, Drijfhout JW, van Tol MJ, et al. Isotype distribution of anti–cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response. Arthritis Rheum 2006;54:3799–808.
    • (2006) Arthritis Rheum , vol.54 , pp. 3799-3808
    • Verpoort, K.N.1    Jol-van der Zijde, C.M.2    Papendrecht-van der Voort, E.A.3    Ioan-Facsinay, A.4    Drijfhout, J.W.5    van Tol, M.J.6
  • 46
    • 74849135762 scopus 로고    scopus 로고
    • Identification of citrullinated vimentin peptides as T cell epitopes in HLA–DR4–positive patients with rheumatoid arthritis
    • Feitsma AL, van der Voort EI, Franken KL, el Bannoudi H, Elferink BG, Drijfhout JW, et al. Identification of citrullinated vimentin peptides as T cell epitopes in HLA–DR4–positive patients with rheumatoid arthritis. Arthritis Rheum 2010;62:117–25.
    • (2010) Arthritis Rheum , vol.62 , pp. 117-125
    • Feitsma, A.L.1    van der Voort, E.I.2    Franken, K.L.3    el Bannoudi, H.4    Elferink, B.G.5    Drijfhout, J.W.6
  • 47
    • 74849112402 scopus 로고    scopus 로고
    • Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis
    • Von Delwig A, Locke J, Robinson JH, Ng WF. Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis. Arthritis Rheum 2010;62:143–9.
    • (2010) Arthritis Rheum , vol.62 , pp. 143-149
    • Von Delwig, A.1    Locke, J.2    Robinson, J.H.3    Ng, W.F.4
  • 48
    • 17644434779 scopus 로고    scopus 로고
    • Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients
    • Folzenlogen D, Hofer MF, Leung DY, Freed JH, Newell MK. Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients. Clin Immunol Immunopathol 1997;83:199–204.
    • (1997) Clin Immunol Immunopathol , vol.83 , pp. 199-204
    • Folzenlogen, D.1    Hofer, M.F.2    Leung, D.Y.3    Freed, J.H.4    Newell, M.K.5
  • 49
    • 77950803212 scopus 로고    scopus 로고
    • B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy
    • Catalan D, Aravena O, Sabugo F, Wurmann P, Soto L, Kalergis AM, et al. B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy. Arthritis Res Ther 2010;12:R68.
    • (2010) Arthritis Res Ther , vol.12 , pp. R68
    • Catalan, D.1    Aravena, O.2    Sabugo, F.3    Wurmann, P.4    Soto, L.5    Kalergis, A.M.6
  • 50
    • 84907192525 scopus 로고    scopus 로고
    • CD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells
    • Schwartz MA, Kolhatkar NS, Thouvenel C, Khim S, Rawlings DJ. CD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells. J Immunol 2014;193:3492–502.
    • (2014) J Immunol , vol.193 , pp. 3492-3502
    • Schwartz, M.A.1    Kolhatkar, N.S.2    Thouvenel, C.3    Khim, S.4    Rawlings, D.J.5
  • 52
    • 84912039241 scopus 로고    scopus 로고
    • Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich–interactive domain 3A
    • Ward JM, Rose K, Montgomery C, Adrianto I, James JA, Merrill JT, et al. Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich–interactive domain 3A. Arthritis Rheumatol 2014;66:3404–12.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 3404-3412
    • Ward, J.M.1    Rose, K.2    Montgomery, C.3    Adrianto, I.4    James, J.A.5    Merrill, J.T.6
  • 53
    • 14844343478 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase regulates immunoglobulin promoter activation in association with the transcription factor Bright
    • Rajaiya J, Hatfield M, Nixon JC, Rawlings DJ, Webb CF. Bruton's tyrosine kinase regulates immunoglobulin promoter activation in association with the transcription factor Bright. Mol Cell Biol 2005;25:2073–84.
    • (2005) Mol Cell Biol , vol.25 , pp. 2073-2084
    • Rajaiya, J.1    Hatfield, M.2    Nixon, J.C.3    Rawlings, D.J.4    Webb, C.F.5
  • 54
    • 84919904707 scopus 로고    scopus 로고
    • Activation of Syk in peripheral blood B cells in patients with rheumatoid arthritis: a potential target for abatacept therapy
    • Iwata S, Nakayamada S, Fukuyo S, Kubo S, Yunoue N, Wang SP, et al. Activation of Syk in peripheral blood B cells in patients with rheumatoid arthritis: a potential target for abatacept therapy. Arthritis Rheumatol 2015;67:63–73.
    • (2015) Arthritis Rheumatol , vol.67 , pp. 63-73
    • Iwata, S.1    Nakayamada, S.2    Fukuyo, S.3    Kubo, S.4    Yunoue, N.5    Wang, S.P.6
  • 55
    • 84964432663 scopus 로고    scopus 로고
    • Fostamatinib, an oral spleen tyrosine kinase inhibitor, in the treatment of rheumatoid arthritis: a meta-analysis of randomized controlled trials
    • Kunwar S, Devkota AR, Ghimire DK. Fostamatinib, an oral spleen tyrosine kinase inhibitor, in the treatment of rheumatoid arthritis: a meta-analysis of randomized controlled trials. Rheumatol Int 2016;36:1077–87.
    • (2016) Rheumatol Int , vol.36 , pp. 1077-1087
    • Kunwar, S.1    Devkota, A.R.2    Ghimire, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.