-
1
-
-
31544442739
-
Epidemiology of primary Sjogren's syndrome in north-west Greece, 1982-2003
-
Alamanos, Y. et al. Epidemiology of primary Sjogren's syndrome in north-west Greece, 1982-2003. Rheumatology (Oxford) 45, 187-191 (2006).
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 187-191
-
-
Alamanos, Y.1
-
2
-
-
1542357595
-
Estimating the prevalence among Caucasian women of primary Sjogren's syndrome in two general practices in Birmingham, UK
-
Bowman, S. J., Ibrahim, G. H., Holmes, G., Hamburger, J. & Ainsworth, J. R. Estimating the prevalence among Caucasian women of primary Sjogren's syndrome in two general practices in Birmingham, UK. Scand. J. Rheumatol. 33, 39-43 (2004).
-
(2004)
Scand. J. Rheumatol.
, vol.33
, pp. 39-43
-
-
Bowman, S.J.1
Ibrahim, G.H.2
Holmes, G.3
Hamburger, J.4
Ainsworth, J.R.5
-
3
-
-
0033069594
-
Prevalence of Sjögren's syndrome in Slovenia
-
Tomsic, M., Logar, D., Grmek, M., Perkovic, T. & Kveder, T. Prevalence of Sjögren's syndrome in Slovenia. Rheumatology (Oxford) 38, 164-170 (1999).
-
(1999)
Rheumatology (Oxford)
, vol.38
, pp. 164-170
-
-
Tomsic, M.1
Logar, D.2
Grmek, M.3
Perkovic, T.4
Kveder, T.5
-
4
-
-
80052227937
-
Sjögren's syndrome: Studying the disease in mice
-
Delaleu, N., Nguyen, C. Q., Peck, A. B. & Jonsson, R. Sjögren's syndrome: studying the disease in mice. Arthritis Res. Ther. 13, 217 (2011).
-
(2011)
Arthritis Res. Ther.
, vol.13
, pp. 217
-
-
Delaleu, N.1
Nguyen, C.Q.2
Peck, A.B.3
Jonsson, R.4
-
5
-
-
77955160246
-
Pathogenesis of Sjögren's syndrome and therapeutic consequences
-
Mariette, X. & Gottenberg, J. E. Pathogenesis of Sjögren's syndrome and therapeutic consequences. Curr. Opin. Rheumatol. 22, 471-477 (2010).
-
(2010)
Curr. Opin. Rheumatol.
, vol.22
, pp. 471-477
-
-
Mariette, X.1
Gottenberg, J.E.2
-
6
-
-
17244372491
-
Activation of the type i interferon system in primary Sjögren's syndrome: A possible etiopathogenic mechanism
-
Bave, U. et al. Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanism. Arthritis Rheum. 52, 1185-1195 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1185-1195
-
-
Bave, U.1
-
7
-
-
84855445128
-
Impact of interleukin-21 in the pathogenesis of primary Sjögren's syndrome: Increased serum levels of interleukin-21 and its expression in the labial salivary glands
-
Kang, K. Y. et al. Impact of interleukin-21 in the pathogenesis of primary Sjögren's syndrome: increased serum levels of interleukin-21 and its expression in the labial salivary glands. Arthritis Res. Ther. 13, R179 (2011).
-
(2011)
Arthritis Res. Ther.
, vol.13
-
-
Kang, K.Y.1
-
8
-
-
44849084239
-
Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways
-
Ittah, M. et al. Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways. Eur. J. Immunol. 38, 1058-1064 (2008).
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1058-1064
-
-
Ittah, M.1
-
9
-
-
37149055953
-
Association of an IRF5 gene functional polymorphism with Sjögren's syndrome
-
Miceli-Richard, C. et al. Association of an IRF5 gene functional polymorphism with Sjögren's syndrome. Arthritis Rheum. 56, 3989-3994 (2007).
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3989-3994
-
-
Miceli-Richard, C.1
-
10
-
-
67650074526
-
The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome
-
Miceli-Richard, C. et al. The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome. Arthritis Rheum. 60, 1991-1997 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1991-1997
-
-
Miceli-Richard, C.1
-
11
-
-
59149104204
-
Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome
-
Nordmark, G. et al. Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome. Genes Immun. 10, 68-76 (2009).
-
(2009)
Genes Immun
, vol.10
, pp. 68-76
-
-
Nordmark, G.1
-
12
-
-
77954886593
-
STAT4 is a confirmed genetic risk factor for Sjögren's syndrome and could be involved in type 1 interferon pathway signaling
-
Gestermann, N. et al. STAT4 is a confirmed genetic risk factor for Sjögren's syndrome and could be involved in type 1 interferon pathway signaling. Genes Immun. 11, 432-438 (2010).
-
(2010)
Genes Immun
, vol.11
, pp. 432-438
-
-
Gestermann, N.1
-
13
-
-
42549147098
-
Variant form of STAT4 is associated with primary Sjögren's syndrome
-
Korman, B. D. et al. Variant form of STAT4 is associated with primary Sjögren's syndrome. Genes Immun. 9, 267-270 (2008).
-
(2008)
Genes Immun
, vol.9
, pp. 267-270
-
-
Korman, B.D.1
-
14
-
-
84883446867
-
Identification of multiple sjögren's syndrome susceptibility loci [abstract OP0020]
-
Lessard, C. J. et al. Identification of multiple Sjögren's syndrome susceptibility loci [abstract OP0020]. Ann.Rheum. Dis. 72 (Suppl. 3), 54 (2013).
-
(2013)
Ann.Rheum. Dis.
, vol.72
, Issue.SUPPL. 3
, pp. 54
-
-
Lessard, C.J.1
-
15
-
-
84875934940
-
The critical importance of epigenetics in autoimmunity
-
Lu, Q. The critical importance of epigenetics in autoimmunity. J. Autoimmun. 41, 1-5 (2013).
-
(2013)
J. Autoimmun.
, vol.41
, pp. 1-5
-
-
Lu, Q.1
-
16
-
-
79551656688
-
MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjögren's syndrome
-
Alevizos, I., Alexander, S., Turner, R. J. & Illei, G. G. MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjögren's syndrome. Arthritis Rheum. 63, 535-544 (2011).
-
(2011)
Arthritis Rheum
, vol.63
, pp. 535-544
-
-
Alevizos, I.1
Alexander, S.2
Turner, R.J.3
Illei, G.G.4
-
17
-
-
0018775078
-
Immune interferon in the circulation of patients with autoimmune disease
-
Hooks, J. J. et al. Immune interferon in the circulation of patients with autoimmune disease. N. Engl. J. Med. 301, 5-8 (1979).
-
(1979)
N. Engl. J. Med.
, vol.301
, pp. 5-8
-
-
Hooks, J.J.1
-
18
-
-
33644530664
-
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome
-
Gottenberg, J. E. et al. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. Proc. Natl Acad. Sci. USA 103, 2770-2775 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 2770-2775
-
-
Gottenberg, J.E.1
-
19
-
-
18644364840
-
Gene expression profiling of minor salivary glands clearly distinguishes primary Sjögren's syndrome patients from healthy control subjects
-
Hjelmervik, T. O., Petersen, K., Jonassen, I., Jonsson, R. & Bolstad, A. I. Gene expression profiling of minor salivary glands clearly distinguishes primary Sjögren's syndrome patients from healthy control subjects. Arthritis Rheum. 52, 1534-1544 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1534-1544
-
-
Hjelmervik, T.O.1
Petersen, K.2
Jonassen, I.3
Jonsson, R.4
Bolstad, A.I.5
-
20
-
-
67349105006
-
Peripheral blood gene expression profiling in Sjögren's syndrome
-
Emamian, E. S. et al. Peripheral blood gene expression profiling in Sjögren's syndrome. Genes Immun. 10, 285-296 (2009).
-
(2009)
Genes Immun
, vol.10
, pp. 285-296
-
-
Emamian, E.S.1
-
21
-
-
70350488070
-
Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3
-
Iwakiri, D. et al. Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3. J. Exp. Med. 206, 2091-2099 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2091-2099
-
-
Iwakiri, D.1
-
22
-
-
58149170722
-
Activation of innate immune responses through Toll-like receptor 3 causes a rapid loss of salivary gland function
-
Deshmukh, U. S., Nandula, S. R., Thimmalapura, P. R., Scindia, Y. M. & Bagavant, H. Activation of innate immune responses through Toll-like receptor 3 causes a rapid loss of salivary gland function. J. Oral Pathol. Med. 38, 42-47 (2009).
-
(2009)
J. Oral Pathol. Med.
, vol.38
, pp. 42-47
-
-
Deshmukh, U.S.1
Nandula, S.R.2
Thimmalapura, P.R.3
Scindia, Y.M.4
Bagavant, H.5
-
23
-
-
77955307228
-
Expression of Toll-like receptors 7, 8, and 9 in primary Sjögren's syndrome
-
Zheng, L., Zhang, Z., Yu, C. & Yang, C. Expression of Toll-like receptors 7, 8, and 9 in primary Sjögren's syndrome. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 109, 844-850 (2010).
-
(2010)
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
, vol.109
, pp. 844-850
-
-
Zheng, L.1
Zhang, Z.2
Yu, C.3
Yang, C.4
-
24
-
-
80054060025
-
Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren's syndrome-like disease
-
Nandula, S. R., Scindia, Y. M., Dey, P., Bagavant, H. & Deshmukh, U. S. Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren's syndrome-like disease. Oral Dis. 17, 801-807 (2011).
-
(2011)
Oral Dis
, vol.17
, pp. 801-807
-
-
Nandula, S.R.1
Scindia, Y.M.2
Dey, P.3
Bagavant, H.4
Deshmukh, U.S.5
-
25
-
-
0030897928
-
Retrovirus in salivary glands from patients with Sjögren's syndrome
-
Yamano, S. et al. Retrovirus in salivary glands from patients with Sjögren's syndrome. J. Clin. Pathol. 50, 223-230 (1997).
-
(1997)
J. Clin. Pathol.
, vol.50
, pp. 223-230
-
-
Yamano, S.1
-
26
-
-
71249087529
-
Primary Sjögren's syndrome: Pathophysiological, clinical and therapeutic advances
-
Gottenberg, J. E. Primary Sjögren's syndrome: pathophysiological, clinical and therapeutic advances. Joint Bone Spine 76, 591-594 (2009).
-
(2009)
Joint Bone Spine
, vol.76
, pp. 591-594
-
-
Gottenberg, J.E.1
-
27
-
-
0032433666
-
Murine cytomegalovirus induces a Sjögren's syndrome-like disease in C57Bl/6-lpr/lpr mice
-
Fleck, M., Kern, E. R., Zhou, T., Lang, B. & Mountz, J. D. Murine cytomegalovirus induces a Sjögren's syndrome-like disease in C57Bl/6-lpr/lpr mice. Arthritis Rheum. 41, 2175-2184 (1998).
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2175-2184
-
-
Fleck, M.1
Kern, E.R.2
Zhou, T.3
Lang, B.4
Mountz, J.D.5
-
28
-
-
79960246157
-
A failure of TNFAIP3 negative regulation maintains sustained NF-κB activation in Sjögren's syndrome
-
Sisto, M. et al. A failure of TNFAIP3 negative regulation maintains sustained NF-κB activation in Sjögren's syndrome. Histochem. Cell Biol. 135, 615-625 (2011).
-
(2011)
Histochem. Cell Biol.
, vol.135
, pp. 615-625
-
-
Sisto, M.1
-
29
-
-
77956996600
-
Defective feedback regulation of NF-κB underlies Sjögren's syndrome in mice with mutated κb enhancers of the IκBα promoter
-
Peng, B. et al. Defective feedback regulation of NF-κB underlies Sjögren's syndrome in mice with mutated κB enhancers of the IκBα promoter. Proc. Natl Acad. Sci. USA 107, 15193-15198 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15193-15198
-
-
Peng, B.1
-
30
-
-
0033428703
-
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
-
Mackay, F. et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190, 1697-1710 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1697-1710
-
-
Mackay, F.1
-
31
-
-
9144234090
-
TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma
-
Batten, M. et al. TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma. J. Immunol. 172, 812-822 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 812-822
-
-
Batten, M.1
-
32
-
-
0037310430
-
The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome
-
Mariette, X. et al. The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome. Ann. Rheum. Dis. 62, 168-171 (2003).
-
(2003)
Ann. Rheum. Dis.
, vol.62
, pp. 168-171
-
-
Mariette, X.1
-
33
-
-
34247230559
-
Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome
-
Daridon, C. et al. Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome. Arthritis Rheum. 56, 1134-1144 (2007).
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1134-1144
-
-
Daridon, C.1
-
34
-
-
38149090131
-
B-cell activating factor of the tumour necrosis factor family expression in blood monocytes and T cells from patients with primary Sjögren's syndrome
-
Lavie, F. et al. B-cell activating factor of the tumour necrosis factor family expression in blood monocytes and T cells from patients with primary Sjögren's syndrome. Scand. J. Immunol. 67, 185-192 (2008).
-
(2008)
Scand. J. Immunol.
, vol.67
, pp. 185-192
-
-
Lavie, F.1
-
35
-
-
0036732753
-
DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
-
Litinskiy, M. B. et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat. Immunol. 3, 822-829 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 822-829
-
-
Litinskiy, M.B.1
-
36
-
-
67649948121
-
B-cell-activating factor expressions in salivary epithelial cells after dsRNA virus infection depends on RNA-activated protein kinase activation
-
Ittah, M. et al. B-cell-activating factor expressions in salivary epithelial cells after dsRNA virus infection depends on RNA-activated protein kinase activation. Eur. J. Immunol. 39, 1271-1279 (2009).
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 1271-1279
-
-
Ittah, M.1
-
37
-
-
79952009770
-
Induction of B cell-activating factor by viral infection is a general phenomenon, but the types of viruses and mechanisms depend on cell type
-
Ittah, M. et al. Induction of B cell-activating factor by viral infection is a general phenomenon, but the types of viruses and mechanisms depend on cell type. J. Innate Immun. 3, 200-207 (2011).
-
(2011)
J. Innate Immun.
, vol.3
, pp. 200-207
-
-
Ittah, M.1
-
38
-
-
84875958991
-
Prevalence of interferon type i signature in CD14 monocytes of patients with Sjögren's syndrome and association with disease activity and BAFF gene expression
-
Brkic, Z. et al. Prevalence of interferon type I signature in CD14 monocytes of patients with Sjögren's syndrome and association with disease activity and BAFF gene expression. Ann. Rheum. Dis. 72, 728-735 (2013).
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 728-735
-
-
Brkic, Z.1
-
39
-
-
0021945723
-
Human B lymphoma cell line producing B cell growth factor
-
Ambrus, J. L. Jr & Fauci, A. S. Human B lymphoma cell line producing B cell growth factor. J. Clin. Invest. 75, 732-739 (1985).
-
(1985)
J. Clin. Invest.
, vol.75
, pp. 732-739
-
-
Ambrus Jr., J.L.1
Fauci, A.S.2
-
40
-
-
33749509230
-
Development of autoimmunity in IL-14α-transgenic mice
-
Shen, L. et al. Development of autoimmunity in IL-14α-transgenic mice. J. Immunol. 177, 5676-5686 (2006).
-
(2006)
J. Immunol.
, vol.177
, pp. 5676-5686
-
-
Shen, L.1
-
41
-
-
59349087482
-
IL-14 alpha, the nexus for primary Sjögren's disease in mice and humans
-
Shen, L. et al. IL-14 alpha, the nexus for primary Sjögren's disease in mice and humans. Clin. Immunol. 130, 304-312 (2009).
-
(2009)
Clin. Immunol.
, vol.130
, pp. 304-312
-
-
Shen, L.1
-
42
-
-
84883458348
-
Stages of Sjögren's syndrome defined by immune mediators [abstract 515]
-
Suresh, L., Ambrus, J. J. & Shen, L. Stages of Sjögren's syndrome defined by immune mediators [abstract 515]. Arthritis Rheum. 64 (Suppl. 10), S225 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, Issue.SUPPL. 10
-
-
Suresh, L.1
Ambrus, J.J.2
Shen, L.3
-
43
-
-
0033017601
-
Increased frequency of cells secreting interleukin-6 and interleukin-10 in peripheral blood of patients with primary Sjögren's syndrome
-
Halse, A., Tengner, P., Wahren-Herlenius, M., Haga, H. & Jonsson, R. Increased frequency of cells secreting interleukin-6 and interleukin-10 in peripheral blood of patients with primary Sjögren's syndrome. Scand. J. Immunol. 49, 533-538 (1999).
-
(1999)
Scand. J. Immunol.
, vol.49
, pp. 533-538
-
-
Halse, A.1
Tengner, P.2
Wahren-Herlenius, M.3
Haga, H.4
Jonsson, R.5
-
44
-
-
0034039608
-
Increased serum levels of interleukin 10 in Sjögren's syndrome; Correlation with increased IgG1
-
Perrier, S. et al. Increased serum levels of interleukin 10 in Sjögren's syndrome; correlation with increased IgG1. J. Rheumatol. 27, 935-939 (2000).
-
(2000)
J. Rheumatol.
, vol.27
, pp. 935-939
-
-
Perrier, S.1
-
45
-
-
14044259331
-
Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: Implications for Burkitt's lymphoma
-
Ogden, C. A. et al. Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma. J. Immunol. 174, 3015-3023 (2005).
-
(2005)
J. Immunol.
, vol.174
, pp. 3015-3023
-
-
Ogden, C.A.1
-
46
-
-
78049527643
-
Regulatory B cells in autoimmunity: Developments and controversies
-
Mauri, C. & Blair, P. A. Regulatory B cells in autoimmunity: developments and controversies. Nat. Rev. Rheumatol. 6, 636-643 (2010).
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, pp. 636-643
-
-
Mauri, C.1
Blair, P.A.2
-
47
-
-
78751469622
-
Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells
-
Iwata, Y. et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood 117, 530-541 (2011).
-
(2011)
Blood
, vol.117
, pp. 530-541
-
-
Iwata, Y.1
-
48
-
-
0036092482
-
Classification criteria for Sjögren's syndrome: A revised version of the European criteria proposed by the American-European Consensus Group
-
Vitali, C. et al. Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann. Rheum. Dis. 61, 554-558 (2002).
-
(2002)
Ann. Rheum. Dis.
, vol.61
, pp. 554-558
-
-
Vitali, C.1
-
49
-
-
33748320925
-
Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block
-
Clancy, R. M. et al. Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block. J. Clin. Invest. 116, 2413-2422 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2413-2422
-
-
Clancy, R.M.1
-
50
-
-
0032430377
-
Detection of anti-Ro/SSA and anti-La/SSB autoantibody-producing cells in salivary glands from patients with Sjögren's syndrome
-
Tengner, P., Halse, A. K., Haga, H. J., Jonsson, R. & Wahren-Herlenius, M. Detection of anti-Ro/SSA and anti-La/SSB autoantibody-producing cells in salivary glands from patients with Sjögren's syndrome. Arthritis Rheum. 41, 2238-2248 (1998).
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2238-2248
-
-
Tengner, P.1
Halse, A.K.2
Haga, H.J.3
Jonsson, R.4
Wahren-Herlenius, M.5
-
51
-
-
67549099572
-
Quantitative assessment of antibodies to ribonucleoproteins in primary Sjögren syndrome: Correlation with B-cell biomarkers and disease activity
-
Candon, S., Gottenberg, J. E., Bengoufa, D., Chatenoud, L. & Mariette, X. Quantitative assessment of antibodies to ribonucleoproteins in primary Sjögren syndrome: correlation with B-cell biomarkers and disease activity. Ann. Rheum. Dis. 68, 1208-1212 (2009).
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1208-1212
-
-
Candon, S.1
Gottenberg, J.E.2
Bengoufa, D.3
Chatenoud, L.4
Mariette, X.5
-
52
-
-
0028809117
-
Intra- and intermolecular spreading of autoimmunity involving the nuclear self-antigens la (SS-B) and Ro (SS-A)
-
Topfer, F., Gordon, T. & McCluskey, J. Intra- and intermolecular spreading of autoimmunity involving the nuclear self-antigens La (SS-B) and Ro (SS-A). Proc. Natl Acad. Sci. USA 92, 875-879 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 875-879
-
-
Topfer, F.1
Gordon, T.2
McCluskey, J.3
-
53
-
-
80155173180
-
Molecular signature of a public clonotypic autoantibody in primary sjögren's syndrome: A "forbidden" clone in systemic autoimmunity
-
Lindop, R. et al. Molecular signature of a public clonotypic autoantibody in primary Sjögren's syndrome: a "forbidden" clone in systemic autoimmunity. Arthritis Rheum. 63, 3477-3486 (2011).
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 3477-3486
-
-
Lindop, R.1
-
54
-
-
84883447199
-
Long-term humoral autoimmunity to Ro60 in primary Sjögren's syndrome is driven by clonal succession [abstract 2676]
-
Lindop, R. et al. Long-term humoral autoimmunity to Ro60 in primary Sjögren's syndrome is driven by clonal succession [abstract 2676]. Arthritis Rheum. 64 (Suppl. 10), S1135 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, Issue.SUPPL. 10
-
-
Lindop, R.1
-
55
-
-
0035152101
-
Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjögren's syndrome
-
Amft, N. et al. Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjögren's syndrome. Arthritis Rheum. 44, 2633-2641 (2001).
-
(2001)
Arthritis Rheum
, vol.44
, pp. 2633-2641
-
-
Amft, N.1
-
56
-
-
84866534641
-
Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice
-
Bombardieri, M. et al. Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice. J. Immunol. 189, 3767-3776 (2012).
-
(2012)
J. Immunol.
, vol.189
, pp. 3767-3776
-
-
Bombardieri, M.1
-
57
-
-
0242663585
-
Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren's syndrome
-
Salomonsson, S. et al. Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren's syndrome. Arthritis Rheum. 48, 3187-3201 (2003).
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3187-3201
-
-
Salomonsson, S.1
-
58
-
-
78149414259
-
The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation
-
Winter, S. et al. The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation. J. Mol. Med. (Berl.) 88, 1169-1180 (2010).
-
(2010)
J. Mol. Med. (Berl.)
, vol.88
, pp. 1169-1180
-
-
Winter, S.1
-
59
-
-
84863605611
-
Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients
-
Maehara, T. et al. Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients. Clin. Exp. Immunol. 169, 89-99 (2012).
-
(2012)
Clin. Exp. Immunol.
, vol.169
, pp. 89-99
-
-
Maehara, T.1
-
60
-
-
84883451204
-
Salivary gland epithelial cells are capable to directly induce the differentiation of IL-21-secreting follicular helper CD4 T cells in primary Sjögren's syndrome [abstract]
-
Gong, Y. et al. Salivary gland epithelial cells are capable to directly induce the differentiation of IL-21-secreting follicular helper CD4 T cells in primary Sjögren's syndrome [abstract]. Arthritis Rheum. 63 (Suppl. 10), 774 (2011).
-
(2011)
Arthritis Rheum.
, vol.63
, Issue.SUPPL. 10
, pp. 774
-
-
Gong, Y.1
-
61
-
-
79953160964
-
Follicular helper T cells in systemic lupus erythematosus: A potential therapeutic target
-
Dong, W., Zhu, P., Wang, Y. & Wang, Z. Follicular helper T cells in systemic lupus erythematosus: a potential therapeutic target. Autoimmun. Rev. 10, 299-304 (2011).
-
(2011)
Autoimmun. Rev.
, vol.10
, pp. 299-304
-
-
Dong, W.1
Zhu, P.2
Wang, Y.3
Wang, Z.4
-
62
-
-
27844511909
-
The risk of lymphoma development in autoimmune diseases: A meta-analysis
-
Zintzaras, E., Voulgarelis, M. & Moutsopoulos, H. M. The risk of lymphoma development in autoimmune diseases: a meta-analysis. Arch. Intern. Med. 165, 2337-2344 (2005).
-
(2005)
Arch. Intern. Med.
, vol.165
, pp. 2337-2344
-
-
Zintzaras, E.1
Voulgarelis, M.2
Moutsopoulos, H.M.3
-
63
-
-
33744503669
-
Lymphoma and other malignancies in primary Sjögren's syndrome: A cohort study on cancer incidence and lymphoma predictors
-
Theander, E. et al. Lymphoma and other malignancies in primary Sjögren's syndrome: a cohort study on cancer incidence and lymphoma predictors. Ann. Rheum. Dis. 65, 796-803 (2006).
-
(2006)
Ann. Rheum. Dis.
, vol.65
, pp. 796-803
-
-
Theander, E.1
-
64
-
-
30344479938
-
Autoimmune and chronic inflammatory disorders and risk of non-Hodgkin lymphoma by subtype
-
Smedby, K. E. et al. Autoimmune and chronic inflammatory disorders and risk of non-Hodgkin lymphoma by subtype. J. Natl Cancer Inst. 98, 51-60 (2006).
-
(2006)
J. Natl Cancer Inst.
, vol.98
, pp. 51-60
-
-
Smedby, K.E.1
-
65
-
-
84857913542
-
Incidence of cancer in a nationwide population cohort of 7,852 patients with primary Sjögren's syndrome in Taiwan
-
Weng, M. Y., Huang, Y. T., Liu, M. F. & Lu, T. H. Incidence of cancer in a nationwide population cohort of 7,852 patients with primary Sjögren's syndrome in Taiwan. Ann. Rheum. Dis. 71, 524-527 (2012).
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 524-527
-
-
Weng, M.Y.1
Huang, Y.T.2
Liu, M.F.3
Lu, T.H.4
-
66
-
-
84876708705
-
Risk of non-hodgkin's lymphoma in primary Sjögren's syndrome: A population-based study
-
Johnsen, S. J. et al. Risk of non-hodgkin's lymphoma in primary Sjögren's syndrome: a population-based study. Arthritis Care Res. (Hoboken) 65, 816-821 (2013).
-
(2013)
Arthritis Care Res. (Hoboken)
, vol.65
, pp. 816-821
-
-
Johnsen, S.J.1
-
67
-
-
0030872542
-
Lymphomas in patients with Sjögren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses
-
Royer, B. et al. Lymphomas in patients with Sjögren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses. Blood 90, 766-775 (1997).
-
(1997)
Blood
, vol.90
, pp. 766-775
-
-
Royer, B.1
-
68
-
-
84855347439
-
Prognosis and outcome of non-Hodgkin lymphoma in primary Sjögren syndrome
-
Voulgarelis, M. et al. Prognosis and outcome of non-Hodgkin lymphoma in primary Sjögren syndrome. Medicine (Baltimore) 91, 1-9 (2012).
-
(2012)
Medicine (Baltimore)
, vol.91
, pp. 1-9
-
-
Voulgarelis, M.1
-
69
-
-
0029989203
-
Clinicopathological factors relating malignant lymphoma with Sjögren's syndrome
-
Anaya, J. M., McGuff, H. S., Banks, P. M. & Talal, N. Clinicopathological factors relating malignant lymphoma with Sjögren's syndrome. Semin. Arthritis Rheum. 25, 337-346 (1996).
-
(1996)
Semin. Arthritis Rheum.
, vol.25
, pp. 337-346
-
-
Anaya, J.M.1
McGuff, H.S.2
Banks, P.M.3
Talal, N.4
-
70
-
-
82955163284
-
Risk, predictors, and clinical characteristics of lymphoma development in primary Sjögren's syndrome
-
Solans-Laque, R. et al. Risk, predictors, and clinical characteristics of lymphoma development in primary Sjögren's syndrome. Semin. Arthritis Rheum. 41, 415-423 (2011).
-
(2011)
Semin. Arthritis Rheum.
, vol.41
, pp. 415-423
-
-
Solans-Laque, R.1
-
71
-
-
0029914461
-
Mixed monoclonal cryoglobulinemia and monoclonal rheumatoid factor cross-reactive idiotypes as predictive factors for the development of lymphoma in primary Sjögren's syndrome
-
Tzioufas, A. G., Boumba, D. S., Skopouli, F. N. & Moutsopoulos, H. M. Mixed monoclonal cryoglobulinemia and monoclonal rheumatoid factor cross-reactive idiotypes as predictive factors for the development of lymphoma in primary Sjögren's syndrome. Arthritis Rheum. 39, 767-772 (1996).
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 767-772
-
-
Tzioufas, A.G.1
Boumba, D.S.2
Skopouli, F.N.3
Moutsopoulos, H.M.4
-
72
-
-
0033496363
-
Malignant lymphoma in primary Sjogren's syndrome: A multicenter, retrospective, clinical study by the European Concerted Action on Sjögren's Syndrome
-
Voulgarelis, M., Dafni, U. G., Isenberg, D. A. & Moutsopoulos, H. M. Malignant lymphoma in primary Sjogren's syndrome: a multicenter, retrospective, clinical study by the European Concerted Action on Sjögren's Syndrome. Arthritis Rheum. 42, 1765-1772 (1999).
-
(1999)
Arthritis Rheum
, vol.42
, pp. 1765-1772
-
-
Voulgarelis, M.1
Dafni, U.G.2
Isenberg, D.A.3
Moutsopoulos, H.M.4
-
73
-
-
0033865077
-
Salivary gland lymphomas in patients with Sjögren's syndrome may frequently develop from rheumatoid factor B cells
-
Martin, T. et al. Salivary gland lymphomas in patients with Sjögren's syndrome may frequently develop from rheumatoid factor B cells. Arthritis Rheum. 43, 908-916 (2000).
-
(2000)
Arthritis Rheum
, vol.43
, pp. 908-916
-
-
Martin, T.1
-
74
-
-
18244385722
-
Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity
-
Bende, R. J. et al. Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity. J. Exp. Med. 201, 1229-1241 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1229-1241
-
-
Bende, R.J.1
-
75
-
-
79959799977
-
Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjögren's syndrome
-
Theander, E. et al. Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjögren's syndrome. Ann. Rheum. Dis. 70, 1363-1368 (2011).
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1363-1368
-
-
Theander, E.1
-
76
-
-
84865134897
-
C-X-C chemokine receptor type 5 gene polymorphisms are associated with non-Hodgkin lymphoma
-
Song, H., Tong, D., Cha, Z. & Bai, J. C-X-C chemokine receptor type 5 gene polymorphisms are associated with non-Hodgkin lymphoma. Mol. Biol. Rep. 39, 8629-8635 (2012).
-
(2012)
Mol. Biol. Rep.
, vol.39
, pp. 8629-8635
-
-
Song, H.1
Tong, D.2
Cha, Z.3
Bai, J.4
-
77
-
-
84878118827
-
Serum levels of beta2-microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjögren's syndrome. Data at enrollment in the prospective ASSESS cohort
-
Gottenberg, J. E. et al. Serum levels of beta2-microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjögren's syndrome. Data at enrollment in the prospective ASSESS cohort. PLoS ONE 8, e59868 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Gottenberg, J.E.1
-
78
-
-
84875684077
-
BLyS upregulation in Sjögren's syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B-cell clonal expansion in the salivary glands
-
Quartuccio, L. et al. BLyS upregulation in Sjögren's syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B-cell clonal expansion in the salivary glands. Rheumatology (Oxford) 52, 276-281 (2013).
-
(2013)
Rheumatology (Oxford)
, vol.52
, pp. 276-281
-
-
Quartuccio, L.1
-
79
-
-
0034774757
-
Lymphomas complicating Sjögren's syndrome and hepatitis C virus infection may share a common pathogenesis: Chronic stimulation of rheumatoid factor B cells
-
Mariette, X. Lymphomas complicating Sjögren's syndrome and hepatitis C virus infection may share a common pathogenesis: chronic stimulation of rheumatoid factor B cells. Ann. Rheum. Dis. 60, 1007-1010 (2001).
-
(2001)
Ann. Rheum. Dis.
, vol.60
, pp. 1007-1010
-
-
Mariette, X.1
-
80
-
-
84881573740
-
Germinal and somatic abnormalities of the TNFAIP3 gene support a two-hit hypothesis of lymphomagenesis in autoimmune disease [abstract]
-
Mariette, X. et al. Germinal and somatic abnormalities of the TNFAIP3 gene support a two-hit hypothesis of lymphomagenesis in autoimmune disease [abstract]. Arthritis Rheum. 63 (Suppl. 10), 161 (2011).
-
(2011)
Arthritis Rheum.
, vol.63
, Issue.SUPPL. 10
, pp. 161
-
-
Mariette, X.1
-
81
-
-
79955471681
-
Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases
-
Musone, S. L. et al. Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases. Genes Immun. 12, 176-182 (2011).
-
(2011)
Genes Immun
, vol.12
, pp. 176-182
-
-
Musone, S.L.1
-
82
-
-
84862134821
-
A20 inactivation in ocular adnexal MALT lymphoma
-
Bi, Y. et al. A20 inactivation in ocular adnexal MALT lymphoma. Haematologica 97, 926-930 (2011).
-
(2011)
Haematologica
, vol.97
, pp. 926-930
-
-
Bi, Y.1
-
83
-
-
70350504882
-
TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas
-
Honma, K. et al. TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas. Blood 114, 2467-2475 (2009).
-
(2009)
Blood
, vol.114
, pp. 2467-2475
-
-
Honma, K.1
-
84
-
-
66649112854
-
Frequent inactivation of A20 in B-cell lymphomas
-
Kato, M. et al. Frequent inactivation of A20 in B-cell lymphomas. Nature 459, 712-716 (2009).
-
(2009)
Nature
, vol.459
, pp. 712-716
-
-
Kato, M.1
-
85
-
-
66549086135
-
The NF-κB negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas
-
Novak, U. et al. The NF-κB negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas. Blood 113, 4918-4921 (2009).
-
(2009)
Blood
, vol.113
, pp. 4918-4921
-
-
Novak, U.1
-
86
-
-
84883457100
-
Germinal and somatic genetic variants of TNFAIP3 promote lymphomagenesis process complicating primary Sjögren's syndrome [abstract OP0023]
-
Nocturne, G. et al. Germinal and somatic genetic variants of TNFAIP3 promote lymphomagenesis process complicating primary Sjögren's syndrome [abstract OP0023]. Ann. Rheum. Dis. 72 (Suppl. 3), 55 (2013).
-
(2013)
Ann. Rheum. Dis.
, vol.72
, Issue.SUPPL. 3
, pp. 55
-
-
Nocturne, G.1
-
87
-
-
84857061990
-
HLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies
-
Cruz-Tapias, P., Rojas-Villarraga, A., Maier-Moore, S. & Anaya, J. M. HLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies. Autoimmun. Rev. 11, 281-287 (2012).
-
(2012)
Autoimmun. Rev.
, vol.11
, pp. 281-287
-
-
Cruz-Tapias, P.1
Rojas-Villarraga, A.2
Maier-Moore, S.3
Anaya, J.M.4
-
88
-
-
0031975394
-
Altered frequency of type 1 cytokine secreting cells in the peripheral blood of patients with primary Sjögren's syndrome
-
Hagiwara, E., Pando, J., Ishigatsubo, Y. & Klinman, D. M. Altered frequency of type 1 cytokine secreting cells in the peripheral blood of patients with primary Sjögren's syndrome. J. Rheumatol. 25, 89-93 (1998).
-
(1998)
J. Rheumatol.
, vol.25
, pp. 89-93
-
-
Hagiwara, E.1
Pando, J.2
Ishigatsubo, Y.3
Klinman, D.M.4
-
89
-
-
10844279142
-
A dual role for interferon-γ in the pathogenesis of Sjögren's syndrome-like autoimmune exocrinopathy in the nonobese diabetic mouse
-
Cha, S. et al. A dual role for interferon-γ in the pathogenesis of Sjögren's syndrome-like autoimmune exocrinopathy in the nonobese diabetic mouse. Scand. J. Immunol. 60, 552-565 (2004).
-
(2004)
Scand. J. Immunol.
, vol.60
, pp. 552-565
-
-
Cha, S.1
-
90
-
-
79953160463
-
Location of immunization and interferon-γ are central to induction of salivary gland dysfunction in Ro60 peptide immunized model of Sjögren's syndrome
-
Yin, H. et al. Location of immunization and interferon-γ are central to induction of salivary gland dysfunction in Ro60 peptide immunized model of Sjögren's syndrome. PLoS ONE 6, e18003 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Yin, H.1
-
91
-
-
33749370410
-
IL-12 overexpression in mice as a model for Sjögren lung disease
-
McGrath-Morrow, S. et al. IL-12 overexpression in mice as a model for Sjögren lung disease. Am. J. Physiol. Lung Cell. Mol. Physiol. 291, L837-L846 (2006).
-
(2006)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.291
-
-
McGrath-Morrow, S.1
-
92
-
-
73249151654
-
Interleukin-12 induces salivary gland dysfunction in transgenic mice, providing a new model of Sjögren's syndrome
-
Vosters, J. L. et al. Interleukin-12 induces salivary gland dysfunction in transgenic mice, providing a new model of Sjögren's syndrome. Arthritis Rheum. 60, 3633-3641 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3633-3641
-
-
Vosters, J.L.1
-
93
-
-
84867907920
-
Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases
-
Hall, J. C. et al. Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases. Proc. Natl Acad. Sci. USA 109, 17609-17614 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 17609-17614
-
-
Hall, J.C.1
-
94
-
-
59849096879
-
Cutting edge: Autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-α in lupus patients in vivo
-
Kariuki, S. N. et al. Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-α in lupus patients in vivo. J. Immunol. 182, 34-38 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 34-38
-
-
Kariuki, S.N.1
-
95
-
-
84883460682
-
Interleukin 12 is involved in an interferon type i signature through crosstalk of CD4+ T cells and plasmacytoid dendritic cells [abstract 2321]
-
Miceli-Richard, C. et al. Interleukin 12 is involved in an interferon type I signature through crosstalk of CD4+ T cells and plasmacytoid dendritic cells [abstract 2321]. Arthritis Rheum. 64 (Suppl. 10), S980 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, Issue.SUPPL. 10
-
-
Miceli-Richard, C.1
-
96
-
-
0035905477
-
Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4+ T cells
-
Geginat, J., Sallusto, F. & Lanzavecchia, A. Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4+ T cells. J. Exp. Med. 194, 1711-1719 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1711-1719
-
-
Geginat, J.1
Sallusto, F.2
Lanzavecchia, A.3
-
97
-
-
77950536542
-
Increased expression of interleukin-7 in labial salivary glands of patients with primary Sjögren's syndrome correlates with increased inflammation
-
Bikker, A. et al. Increased expression of interleukin-7 in labial salivary glands of patients with primary Sjögren's syndrome correlates with increased inflammation. Arthritis Rheum. 62, 969-977 (2010).
-
(2010)
Arthritis Rheum
, vol.62
, pp. 969-977
-
-
Bikker, A.1
-
98
-
-
84860917111
-
Increased interleukin (IL)-7Rα expression in salivary glands of patients with primary Sjögren's syndrome is restricted to T cells and correlates with IL-7 expression, lymphocyte numbers and activity
-
Bikker, A. et al. Increased interleukin (IL)-7Rα expression in salivary glands of patients with primary Sjögren's syndrome is restricted to T cells and correlates with IL-7 expression, lymphocyte numbers and activity. Ann. Rheum. Dis. 71, 1027-1033 (2012).
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 1027-1033
-
-
Bikker, A.1
-
99
-
-
84868377611
-
Clinical efficacy of leflunomide in primary Sjögren's syndrome is associated with regulation of T-cell activity and upregulation of IL-7 receptor alpha expression
-
Bikker, A. et al. Clinical efficacy of leflunomide in primary Sjögren's syndrome is associated with regulation of T-cell activity and upregulation of IL-7 receptor alpha expression. Ann. Rheum. Dis. 71, 1934-1941 (2012).
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 1934-1941
-
-
Bikker, A.1
-
100
-
-
70349244787
-
Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesis
-
Katsifis, G. E., Rekka, S., Moutsopoulos, N. M., Pillemer, S. & Wahl, S. M. Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesis. Am. J. Pathol. 175, 1167-1177 (2009).
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 1167-1177
-
-
Katsifis, G.E.1
Rekka, S.2
Moutsopoulos, N.M.3
Pillemer, S.4
Wahl, S.M.5
-
101
-
-
53149131365
-
Identification of IL-18 and TH17 cells in salivary glands of patients with Sjögren's syndrome, and amplification of IL-17-mediated secretion of inflammatory cytokines from salivary gland cells by IL-18
-
Sakai, A., Sugawara, Y., Kuroishi, T., Sasano, T. & Sugawara, S. Identification of IL-18 and TH17 cells in salivary glands of patients with Sjögren's syndrome, and amplification of IL-17-mediated secretion of inflammatory cytokines from salivary gland cells by IL-18. J. Immunol. 181, 2898-2906 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 2898-2906
-
-
Sakai, A.1
Sugawara, Y.2
Kuroishi, T.3
Sasano, T.4
Sugawara, S.5
-
102
-
-
55349085462
-
Foxp3+ T-regulatory cells in Sjögren's syndrome: Correlation with the grade of the autoimmune lesion and certain adverse prognostic factors
-
Christodoulou, M. I., Kapsogeorgou, E. K., Moutsopoulos, N. M. & Moutsopoulos, H. M. Foxp3+ T-regulatory cells in Sjögren's syndrome: correlation with the grade of the autoimmune lesion and certain adverse prognostic factors. Am. J. Pathol. 173, 1389-1396 (2008).
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 1389-1396
-
-
Christodoulou, M.I.1
Kapsogeorgou, E.K.2
Moutsopoulos, N.M.3
Moutsopoulos, H.M.4
-
103
-
-
76049096595
-
The numbers of Foxp3+ TREG cells are positively correlated with higher grade of infiltration at the salivary glands in primary Sjögren's syndrome
-
Sarigul, M. et al. The numbers of Foxp3+ TREG cells are positively correlated with higher grade of infiltration at the salivary glands in primary Sjögren's syndrome. Lupus 19, 138-145 (2010).
-
(2010)
Lupus
, vol.19
, pp. 138-145
-
-
Sarigul, M.1
-
104
-
-
17444366917
-
CD4 CD25high regulatory T cells are not impaired in patients with primary Sjögren's syndrome
-
Gottenberg, J. E. et al. CD4 CD25high regulatory T cells are not impaired in patients with primary Sjögren's syndrome. J. Autoimmun. 24, 235-242 (2005).
-
(2005)
J. Autoimmun.
, vol.24
, pp. 235-242
-
-
Gottenberg, J.E.1
-
105
-
-
84855350256
-
Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren's syndrome
-
Ciccia, F. et al. Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren's syndrome. Ann. Rheum. Dis. 71, 295-301 (2012).
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 295-301
-
-
Ciccia, F.1
-
106
-
-
77954627022
-
Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity
-
Cella, M., Otero, K. & Colonna, M. Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity. Proc. Natl Acad. Sci. USA 107, 10961-10966 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10961-10966
-
-
Cella, M.1
Otero, K.2
Colonna, M.3
-
107
-
-
84883460952
-
Genetic variation at the NCR3 locus is associated with risk of primary Sjögren's syndrome and implicates a role for NK cells in this autoimmune disease [abstract]
-
Miceli-Richard, C. et al. Genetic variation at the NCR3 locus is associated with risk of primary Sjögren's syndrome and implicates a role for NK cells in this autoimmune disease [abstract]. Ann. Rheum. Dis. 70 (Suppl. 3), 212 (2011).
-
(2011)
Ann. Rheum. Dis.
, vol.70
, Issue.SUPPL. 3
, pp. 212
-
-
Miceli-Richard, C.1
-
108
-
-
84883455702
-
Genetic and functional analyses implicate NCR3NKp30 in the pathogenesis of primary sjögren's syndrome
-
in press
-
Nocturne, G. et al. Genetic and functional analyses implicate NCR3/NKp30 in the pathogenesis of primary Sjögren's syndrome. Sci. Transl. Med. (in press).
-
Sci. Transl. Med.
-
-
Nocturne, G.1
-
109
-
-
84883462313
-
Genetic variation in the NCR3 locus is associated with anti-SSA/SSB positive primary Sjögren's syndrome in Scandinavian samples [abstract 522]
-
Nordmark, G. et al. Genetic variation in the NCR3 locus is associated with anti-SSA/SSB positive primary Sjögren's syndrome in Scandinavian samples [abstract 522]. Arthritis Rheum. 64 (Suppl. 10), S228 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, Issue.SUPPL. 10
-
-
Nordmark, G.1
-
110
-
-
34447636217
-
Hypothalamic-pituitary-adrenal axis function in Sjögren's syndrome: Mechanisms of neuroendocrine and immune system homeostasis
-
Johnson, E. O., Kostandi, M. & Moutsopoulos, H. M. Hypothalamic-pituitary-adrenal axis function in Sjögren's syndrome: mechanisms of neuroendocrine and immune system homeostasis. Ann. NY Acad. Sci. 1088, 41-51 (2006).
-
(2006)
Ann. NY Acad. Sci.
, vol.1088
, pp. 41-51
-
-
Johnson, E.O.1
Kostandi, M.2
Moutsopoulos, H.M.3
-
111
-
-
0031880285
-
Hypofunction of the stress axis in Sjögren's syndrome
-
Johnson, E. O., Vlachoyiannopoulos, P. G., Skopouli, F. N., Tzioufas, A. G. & Moutsopoulos, H. M. Hypofunction of the stress axis in Sjögren's syndrome. J. Rheumatol. 25, 1508-1514 (1998).
-
(1998)
J. Rheumatol.
, vol.25
, pp. 1508-1514
-
-
Johnson, E.O.1
Vlachoyiannopoulos, P.G.2
Skopouli, F.N.3
Tzioufas, A.G.4
Moutsopoulos, H.M.5
-
112
-
-
48349134260
-
Neuroendocrine dysfunction in Sjögren's syndrome
-
Tzioufas, A. G., Tsonis, J. & Moutsopoulos, H. M. Neuroendocrine dysfunction in Sjögren's syndrome. Neuroimmunomodulation 15, 37-45 (2008).
-
(2008)
Neuroimmunomodulation
, vol.15
, pp. 37-45
-
-
Tzioufas, A.G.1
Tsonis, J.2
Moutsopoulos, H.M.3
-
113
-
-
0141425633
-
Development of autoimmune exocrinopathy resembling Sjögren's syndrome in estrogen-deficient mice of healthy background
-
Ishimaru, N. et al. Development of autoimmune exocrinopathy resembling Sjögren's syndrome in estrogen-deficient mice of healthy background. Am. J. Pathol. 163, 1481-1490 (2003).
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 1481-1490
-
-
Ishimaru, N.1
-
114
-
-
58149288276
-
Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome-like autoimmune exocrinopathy
-
Ishimaru, N. et al. Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome-like autoimmune exocrinopathy. J. Exp. Med. 205, 2915-2927 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2915-2927
-
-
Ishimaru, N.1
-
115
-
-
70349220968
-
Functional estrogen receptors alpha and beta are expressed in normal human salivary gland epithelium and apparently mediate immunomodulatory effects
-
Tsinti, M. et al. Functional estrogen receptors alpha and beta are expressed in normal human salivary gland epithelium and apparently mediate immunomodulatory effects. Eur. J. Oral Sci. 117, 498-505 (2009).
-
(2009)
Eur. J. Oral Sci.
, vol.117
, pp. 498-505
-
-
Tsinti, M.1
-
116
-
-
0028170135
-
Sjögren's syndrome: Autoimmune epithelitis
-
Moutsopoulos, H. M. Sjögren's syndrome: autoimmune epithelitis. Clin. Immunol. Immunopathol. 72, 162-165 (1994).
-
(1994)
Clin. Immunol. Immunopathol.
, vol.72
, pp. 162-165
-
-
Moutsopoulos, H.M.1
-
117
-
-
0029892213
-
Genetically programmed development of salivary gland abnormalities in the NOD (nonobese diabetic)-SCID mouse in the absence of detectable lymphocytic infiltration: A potential trigger for sialoadenitis of NOD mice
-
Robinson, C. P., Yamamoto, H., Peck, A. B. & Humphreys-Beher, M. G. Genetically programmed development of salivary gland abnormalities in the NOD (nonobese diabetic)-SCID mouse in the absence of detectable lymphocytic infiltration: a potential trigger for sialoadenitis of NOD mice. Clin. Immunol. Immunopathol. 79, 50-59 (1996).
-
(1996)
Clin. Immunol. Immunopathol.
, vol.79
, pp. 50-59
-
-
Robinson, C.P.1
Yamamoto, H.2
Peck, A.B.3
Humphreys-Beher, M.G.4
-
118
-
-
0035284814
-
Functional expression of a costimulatory B7.2 (CD86) protein on human salivary gland epithelial cells that interacts with the CD28 receptor, but has reduced binding to CTLA4
-
Kapsogeorgou, E. K., Moutsopoulos, H. M. & Manoussakis, M. N. Functional expression of a costimulatory B7.2 (CD86) protein on human salivary gland epithelial cells that interacts with the CD28 receptor, but has reduced binding to CTLA4. J. Immunol. 166, 3107-3113 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 3107-3113
-
-
Kapsogeorgou, E.K.1
Moutsopoulos, H.M.2
Manoussakis, M.N.3
-
119
-
-
0033045115
-
Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sjögren's syndrome
-
Manoussakis, M. N. et al. Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sjögren's syndrome. Arthritis Rheum. 42, 229-239 (1999).
-
(1999)
Arthritis Rheum
, vol.42
, pp. 229-239
-
-
Manoussakis, M.N.1
-
120
-
-
70350612907
-
B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome
-
Ittah, M. et al. B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome. Arthritis Res. Ther. 8, R51 (2006).
-
(2006)
Arthritis Res. Ther.
, vol.8
-
-
Ittah, M.1
-
122
-
-
18644377363
-
Salivary gland epithelial cell exosomes: A source of autoantigenic ribonucleoproteins
-
Kapsogeorgou, E. K., Abu-Helu, R. F., Moutsopoulos, H. M. & Manoussakis, M. N. Salivary gland epithelial cell exosomes: A source of autoantigenic ribonucleoproteins. Arthritis Rheum. 52, 1517-1521 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1517-1521
-
-
Kapsogeorgou, E.K.1
Abu-Helu, R.F.2
Moutsopoulos, H.M.3
Manoussakis, M.N.4
-
123
-
-
54349116244
-
Reduction of fatigue in Sjögren syndrome with rituximab: Results of a randomised, double-blind, placebo-controlled pilot study
-
Dass, S. et al. Reduction of fatigue in Sjögren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study. Ann. Rheum. Dis. 67, 1541-1544 (2008).
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 1541-1544
-
-
Dass, S.1
-
124
-
-
77950538947
-
Effectiveness of rituximab treatment in primary Sjögren's syndrome: A randomized, double-blind, placebo-controlled trial
-
Meijer, J. M. et al. Effectiveness of rituximab treatment in primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 62, 960-968 (2010).
-
(2010)
Arthritis Rheum
, vol.62
, pp. 960-968
-
-
Meijer, J.M.1
-
125
-
-
34047177483
-
Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjögren's syndrome
-
Seror, R. et al. Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjögren's syndrome. Ann. Rheum. Dis. 66, 351-357 (2007).
-
(2007)
Ann. Rheum. Dis.
, vol.66
, pp. 351-357
-
-
Seror, R.1
-
126
-
-
84881218563
-
Efficacy of belimumab on non-malignant parotid swelling and systemic manifestations of Sjögren's syndrome: Results of the Beliss study [abstract 2189]
-
De Vita, S. et al. Efficacy of belimumab on non-malignant parotid swelling and systemic manifestations of Sjögren's syndrome: results of the Beliss study [abstract 2189]. Arthritis Rheum. 64 (Suppl. 10), S926 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, Issue.SUPPL. 10
-
-
De Vita, S.1
-
127
-
-
0032903599
-
Dendritic cells directly trigger NK cell functions: Cross-talk relevant in innate anti-tumor immune responses in vivo
-
Fernandez, N. C. et al. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nat. Med. 5, 405-411 (1999).
-
(1999)
Nat. Med.
, vol.5
, pp. 405-411
-
-
Fernandez, N.C.1
-
128
-
-
0037017381
-
Reciprocal activating interaction between natural killer cells and dendritic cells
-
Gerosa, F. et al. Reciprocal activating interaction between natural killer cells and dendritic cells. J. Exp. Med. 195, 327-333 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 327-333
-
-
Gerosa, F.1
-
129
-
-
26844581032
-
Natural-killer cells and dendritic cells: "l'union fait la force"
-
Walzer, T., Dalod, M., Robbins, S. H., Zitvogel, L. & Vivier, E. Natural-killer cells and dendritic cells: "l'union fait la force". Blood 106, 2252-2258 (2005).
-
(2005)
Blood
, vol.106
, pp. 2252-2258
-
-
Walzer, T.1
Dalod, M.2
Robbins, S.H.3
Zitvogel, L.4
Vivier, E.5
-
130
-
-
84868363350
-
Low copy number of the Fc-gamma receptor 3B gene FCGR3B is a risk factor for primary Sjögren's syndrome
-
Nossent, J. C., Rischmueller, M. & Lester, S. Low copy number of the Fc-gamma receptor 3B gene FCGR3B is a risk factor for primary Sjögren's syndrome. J. Rheumatol. 39, 2142-2147 (2012).
-
(2012)
J. Rheumatol.
, vol.39
, pp. 2142-2147
-
-
Nossent, J.C.1
Rischmueller, M.2
Lester, S.3
-
131
-
-
84860918960
-
Association between genetic variants in the tumour necrosis factor/lymphotoxin alpha/lymphotoxin beta locus and primary Sjögren's syndrome in Scandinavian samples
-
Bolstad, A. I. et al. Association between genetic variants in the tumour necrosis factor/lymphotoxin alpha/lymphotoxin beta locus and primary Sjögren's syndrome in Scandinavian samples. Ann. Rheum. Dis. 71, 981-988 (2012).
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 981-988
-
-
Bolstad, A.I.1
-
132
-
-
0035016886
-
Polymorphisms of the mannose binding lectin gene in patients with Sjögren's syndrome
-
Wang, Z. Y., Morinobu, A., Kanagawa, S. & Kumagai, S. Polymorphisms of the mannose binding lectin gene in patients with Sjögren's syndrome. Ann. Rheum. Dis. 60, 483-486 (2001).
-
(2001)
Ann. Rheum. Dis.
, vol.60
, pp. 483-486
-
-
Wang, Z.Y.1
Morinobu, A.2
Kanagawa, S.3
Kumagai, S.4
-
133
-
-
51349083551
-
IκBα promoter polymorphisms in patients with primary Sjögren's syndrome
-
Ou, T. T. et al. IκBα promoter polymorphisms in patients with primary Sjögren's syndrome. J. Clin. Immunol. 28, 440-444 (2008).
-
(2008)
J. Clin. Immunol.
, vol.28
, pp. 440-444
-
-
Ou, T.T.1
-
134
-
-
0036301115
-
TAP, HLA-DQB1, and HLA-DRB1 polymorphism in Colombian patients with primary Sjögren's syndrome
-
Anaya, J. M., Correa, P. A., Mantilla, R. D. & Arcos-Burgos, M. TAP, HLA-DQB1, and HLA-DRB1 polymorphism in Colombian patients with primary Sjögren's syndrome. Semin. Arthritis Rheum. 31, 396-405 (2002).
-
(2002)
Semin. Arthritis Rheum.
, vol.31
, pp. 396-405
-
-
Anaya, J.M.1
Correa, P.A.2
Mantilla, R.D.3
Arcos-Burgos, M.4
-
135
-
-
79952280367
-
Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome
-
Nordmark, G. et al. Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome. Genes Immun. 12, 100-109 (2011).
-
(2011)
Genes Immun
, vol.12
, pp. 100-109
-
-
Nordmark, G.1
-
136
-
-
27844441281
-
PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases
-
Gomez, L. M. et al. PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases. Genes Immun. 6, 628-631 (2005).
-
(2005)
Genes Immun
, vol.6
, pp. 628-631
-
-
Gomez, L.M.1
-
137
-
-
0036709574
-
CC chemokine receptor 5 and interleukin-1 receptor antagonist gene polymorphisms in patients with primary Sjögren's syndrome
-
Petrek, M. et al. CC chemokine receptor 5 and interleukin-1 receptor antagonist gene polymorphisms in patients with primary Sjögren's syndrome. Clin. Exp. Rheumatol. 20, 701-703 (2002).
-
(2002)
Clin. Exp. Rheumatol.
, vol.20
, pp. 701-703
-
-
Petrek, M.1
-
138
-
-
0035147109
-
Genetic association between interleukin-10 promoter region polymorphisms and primary Sjögren's syndrome
-
Hulkkonen, J. et al. Genetic association between interleukin-10 promoter region polymorphisms and primary Sjögren's syndrome. Arthritis Rheum. 44, 176-179 (2001).
-
(2001)
Arthritis Rheum
, vol.44
, pp. 176-179
-
-
Hulkkonen, J.1
-
139
-
-
0018220157
-
Increased risk of lymphoma in sicca syndrome
-
Kassan, S. S. et al. Increased risk of lymphoma in sicca syndrome. Ann. Intern. Med. 89, 888-892 (1978).
-
(1978)
Ann. Intern. Med.
, vol.89
, pp. 888-892
-
-
Kassan, S.S.1
-
140
-
-
0031451930
-
Differential risk of non-Hodgkin's lymphoma in Italian patients with primary Sjögren's syndrome
-
Valesini, G. et al. Differential risk of non-Hodgkin's lymphoma in Italian patients with primary Sjögren's syndrome. J. Rheumatol. 24, 2376-2380 (1997).
-
(1997)
J. Rheumatol.
, vol.24
, pp. 2376-2380
-
-
Valesini, G.1
-
141
-
-
0030942071
-
Elevated incidence of hematologic malignancies in patients with Sjögren's syndrome compared with patients with rheumatoid arthritis (Finland)
-
Kauppi, M., Pukkala, E. & Isomaki, H. Elevated incidence of hematologic malignancies in patients with Sjögren's syndrome compared with patients with rheumatoid arthritis (Finland). Cancer Causes Control 8, 201-204 (1997).
-
(1997)
Cancer Causes Control
, vol.8
, pp. 201-204
-
-
Kauppi, M.1
Pukkala, E.2
Isomaki, H.3
-
142
-
-
0035023371
-
A longitudinal cohort study of Finnish patients with primary Sjögren's syndrome: Clinical, immunological, and epidemiological aspects
-
Pertovaara, M., Pukkala, E., Laippala, P., Miettinen, A. & Pasternack, A. A longitudinal cohort study of Finnish patients with primary Sjögren's syndrome: clinical, immunological, and epidemiological aspects. Ann. Rheum. Dis. 60, 467-472 (2001).
-
(2001)
Ann. Rheum. Dis.
, vol.60
, pp. 467-472
-
-
Pertovaara, M.1
Pukkala, E.2
Laippala, P.3
Miettinen, A.4
Pasternack, A.5
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