Alternate replication in B cells and epithelial cells switches tropism of Epstein-Barr virus

Nature Medicine

Volumn 8, Issue 6, 2002, Pages 594-599

  Borza, Corina M ^a   Hutt Fletcher, Lindsey M ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; HLA ANTIGEN CLASS 2;

ARTICLE; B LYMPHOCYTE; CELL DIVISION; CELL LINE; COMPLEX FORMATION; EPITHELIUM CELL; EPSTEIN BARR VIRUS; PHENOTYPE; PRIORITY JOURNAL; VIRUS INFECTION; VIRUS PATHOGENESIS;

ANIMALS; B-LYMPHOCYTES; CELL LINE; DNA, VIRAL; EPITHELIAL CELLS; GENE DELETION; HERPESVIRUS 4, HUMAN; HISTOCOMPATIBILITY ANTIGENS CLASS II; LYMPHOCYTE ACTIVATION; THYMIDINE KINASE; VIRUS REPLICATION; VIRUS SHEDDING;

DNA VIRUSES; HUMAN HERPESVIRUS 4;

EID: 0036284985     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0602-594     Document Type: Article

References (27)

1. Epstein-Barr virus
2. Three classes of cell surface receptors for alphaherpesvirus entry
3. Identification of gp350 as the viral glycoprotein mediating attachment of Epstein-Barr virus (EBV) to the EBV/C3d receptor of B cells: Sequence homology of gp 350 and C3 complement fragment C3d
4. Epstein-Barr virus gp350/220 binding to the B lymphocyte C3d receptor mediates adsorption, capping and endocytosis
5. Epstein-Barr virus receptor of human B lymphocytes is the C3d complement CR2
6. Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2)
7. Epstein-Barr virus gH is essential for penetration of B cell but also plays a role in attachment of virus to epithelial cells
8. A monoclonal antibody to glycoprotein gp85 inhibits fusion but not attachment of Epstein-Barr virus
9. Depletion of glycoprotein gp85 from virosomes made with Epstein-Barr virus proteins abolishes their ability to fuse with virus receptor-bearing cells
10. The Epstein-Barr virus (EBV) BZLF 2 gene product associates with the gH and gL homologs of EBV and carries an epitope critical to infection of B cells but not of epithelial cells
11. Epstein-Barr virus lacking glycoprotein gp42 can bind to B cells but is not able to infect
12. Epstein-Barr virus uses HLA class II as a cofactor for infection of B lymphocytes
13. Epstein-Barr virus entry utilizing HLA-DP or HLA-DQ as a coreceptor
14. Coreceptor restriction within the HLA-DQ locus for Epstein-Barr virus infection
15. Epstein-Barr virus uses different complexes of glycoproteins gH and gL to infect B lymphocytes and epithelial cells
16. Epstein-Barr virus recombinant lacking expression of glycoprotein gp 150 infects B cells normally but is enhanced for infection of the epithelial line SVKCR2
17. Lonely MHC molecules seeking immunogenic peptides for meaningful relationships
18. Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatability complex class II genes
19. Retroviridae: The retroviruses and their replication
20. Cellular expression of alphaherpesvirus gD interferes with entry of homologous and heterologous alphaherpesviruses by blocking access to a shared gD receptor
21. Epstein-Barr virus infection and replication in a human epithelial system
22. Virologic, immunologic, and clinical observations on a patient during the incubation, acute and convalescent phases of infectious mononucleosis
23. + T cells during the primary immune response to Epstein-Barr virus in vivo
24. An animal model for acute and persistent Epstein-Barr virus infection
25. Specific anti-mononuclear antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages
26. Cross-linking of cell surface immunoglobulin induces Epstein-Barr virus in Burkitt lymphoma lines
27. Epstein-Barr virus glycoprotein gp85 associates with the BKRF2 gene product and is incompletely processed as a recombinant protein