Defective DNA methylation in salivary gland epithelial acini from patients with Sjögren's syndrome is associated with SSB gene expression, anti-SSB/LA detection, and lymphocyte infiltration

Journal of Autoimmunity

Volumn 68, Issue , 2016, Pages 30-38

  Konsta, O D ^a,b   Le Dantec, C ^a   Charras, A ^a   Cornec, D ^a   Kapsogeorgou, E K ^b   Tzioufas, A G ^b   Pers, J O ^a   Renaudineau, Y ^a,c  

^a Universite de Brest   (France)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c CHU MORVAN   (France)

Author keywords

Anti SSB antibodies; DNA demethylation; Lymphocytes; Sj gren's syndrome

Indexed keywords

AZACITIDINE; CYTOKERATIN ANTIBODY; LA ANTIBODY; MESSENGER RNA; METHYLATION SENSITIVE RESTRICTION ENZYME; RESTRICTION ENDONUCLEASE; UNCLASSIFIED DRUG; ANTINUCLEAR ANTIBODY; LA PROTEIN, HUMAN; PHOSPHOPROTEIN; SS-B ANTIBODIES;

ADULT; AGED; ANTIBODY DETECTION; ARTICLE; CELL INFILTRATION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DNA METHYLATION; EPITHELIUM CELL; EXON; GENE; GENE CONTROL; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; LYMPHOCYTE; MINOR SALIVA GLAND; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SJOEGREN SYNDROME; SSB GENE; WESTERN BLOTTING; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; SJOGREN'S SYNDROME; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, ANTINUCLEAR; AZACITIDINE; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; PHOSPHOPROTEINS; SALIVARY GLANDS, MINOR; SJOGREN'S SYNDROME; YOUNG ADULT;

EID: 84960091697     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2015.12.002     Document Type: Article

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