메뉴 건너뛰기




Volumn 189, Issue 7, 2012, Pages 3767-3776

Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; ADENOVIRUS VECTOR; ANTINUCLEAR ANTIBODY; CXCL13 CHEMOKINE; LYMPHOTOXIN BETA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA;

EID: 84866534641     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201216     Document Type: Article
Times cited : (102)

References (48)
  • 1
    • 33645106845 scopus 로고    scopus 로고
    • Lymphoid organ development: From ontogeny to neogenesis
    • Drayton, D. L., S. Liao, R. H. Mounzer, and N. H. Ruddle. 2006. Lymphoid organ development: from ontogeny to neogenesis. Nat. Immunol. 7: 344-353.
    • (2006) Nat. Immunol. , vol.7 , pp. 344-353
    • Drayton, D.L.1    Liao, S.2    Mounzer, R.H.3    Ruddle, N.H.4
  • 2
    • 33344475672 scopus 로고    scopus 로고
    • Lymphoid neogenesis in chronic inflammatory diseases
    • DOI 10.1038/nri1786
    • Aloisi, F., and R. Pujol-Borrell. 2006. Lymphoid neogenesis in chronic inflammatory diseases. Nat. Rev. Immunol. 6: 205-217. (Pubitemid 43290990)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.3 , pp. 205-217
    • Aloisi, F.1    Pujol-Borrell, R.2
  • 3
    • 73249126744 scopus 로고    scopus 로고
    • Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: From inflammation to autoimmunity and tissue damage/remodeling
    • Manzo, A., M. Bombardieri, F. Humby, and C. Pitzalis. 2010. Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling. Immunol. Rev. 233: 267-285.
    • (2010) Immunol. Rev. , vol.233 , pp. 267-285
    • Manzo, A.1    Bombardieri, M.2    Humby, F.3    Pitzalis, C.4
  • 4
    • 0842281434 scopus 로고    scopus 로고
    • The clinical value of intracellular autoantigens B-cell epitopes in systemic rheumatic diseases
    • DOI 10.1016/j.cccn.2003.10.011
    • Routsias, J. G., A. G. Tzioufas, and H. M. Moutsopoulos. 2004. The clinical value of intracellular autoantigens B-cell epitopes in systemic rheumatic diseases. Clin. Chim. Acta 340: 1-25. (Pubitemid 38167505)
    • (2004) Clinica Chimica Acta , vol.340 , Issue.1-2 , pp. 1-25
    • Routsias, J.G.1    Tzioufas, A.G.2    Moutsopoulos, H.M.3
  • 5
    • 0014330331 scopus 로고
    • Labial salivary gland biopsy in Sjögren's disease
    • Chisholm, D. M., and D. K. Mason. 1968. Labial salivary gland biopsy in Sjögren's disease. J. Clin. Pathol. 21: 656-660.
    • (1968) J. Clin. Pathol. , vol.21 , pp. 656-660
    • Chisholm, D.M.1    Mason, D.K.2
  • 6
    • 35148885813 scopus 로고    scopus 로고
    • Serological implications of germinal center-like structures in primary Sjögren's syndrome
    • Jonsson, M. V., K. Skarstein, R. Jonsson, and J. G. Brun. 2007. Serological implications of germinal center-like structures in primary Sjögren's syndrome. J. Rheumatol. 34: 2044-2049. (Pubitemid 47548208)
    • (2007) Journal of Rheumatology , vol.34 , Issue.10 , pp. 2044-2049
    • Jonsson, M.V.1    Skarstein, K.2    Jonsson, R.3    Brun, J.G.4
  • 7
    • 20744455989 scopus 로고    scopus 로고
    • Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjögren's syndrome
    • DOI 10.1002/art.21062
    • Barone, F., M. Bombardieri, A. Manzo, M. C. Blades, P. R. Morgan, S. J. Challacombe, G. Valesini, and C. Pitzalis. 2005. Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjögren's syndrome. Arthritis Rheum. 52: 1773-1784. (Pubitemid 40852886)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.6 , pp. 1773-1784
    • Barone, F.1    Bombardieri, M.2    Manzo, A.3    Blades, M.C.4    Morgan, P.R.5    Challacombe, S.J.6    Valesini, G.7    Pitzalis, C.8
  • 8
    • 0035089844 scopus 로고    scopus 로고
    • "Lymphoid" chemokine messenger RNA expression by epithelial cells in the chronic inflammatory lesion of the salivary glands of Sjögren's syndrome patients: Possible participation in lymphoid structure formation
    • Xanthou, G., M. Polihronis, A. G. Tzioufas, S. Paikos, P. Sideras, and H. M. Moutsopoulos. 2001. "Lymphoid" chemokine messenger RNA expression by epithelial cells in the chronic inflammatory lesion of the salivary glands of Sjögren's syndrome patients: possible participation in lymphoid structure formation. Arthritis Rheum. 44: 408-418.
    • (2001) Arthritis Rheum. , vol.44 , pp. 408-418
    • Xanthou, G.1    Polihronis, M.2    Tzioufas, A.G.3    Paikos, S.4    Sideras, P.5    Moutsopoulos, H.M.6
  • 9
    • 0035152101 scopus 로고    scopus 로고
    • Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjögren's syndrome
    • DOI 10.1002/1529-0131(200111)44:11<2633::AID-ART443>3.0.CO;2-9
    • Amft, N., S. J. Curnow, D. Scheel-Toellner, A. Devadas, J. Oates, J. Crocker, J. Hamburger, J. Ainsworth, J. Mathews, M. Salmon, et al. 2001. Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjögren's syndrome. Arthritis Rheum. 44: 2633-2641. (Pubitemid 33049341)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.11 , pp. 2633-2641
    • Amft, N.1    Curnow, S.J.2    Scheel-Toellner, D.3    Devadas, A.4    Oates, J.5    Crocker, J.6    Hamburger, J.7    Ainsworth, J.8    Mathews, J.9    Salmon, M.10    Bowman, S.J.11    Buckley, C.D.12
  • 10
    • 43349091335 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjögren's syndrome
    • Bombardieri, M., F. Barone, F. Humby, S. Kelly, M. McGurk, P. Morgan, S. Challacombe, S. De Vita, G. Valesini, J. Spencer, and C. Pitzalis. 2007. Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjögren's syndrome. J. Immunol. 179: 4929-4938.
    • (2007) J. Immunol. , vol.179 , pp. 4929-4938
    • Bombardieri, M.1    Barone, F.2    Humby, F.3    Kelly, S.4    McGurk, M.5    Morgan, P.6    Challacombe, S.7    De Vita, S.8    Valesini, G.9    Spencer, J.10    Pitzalis, C.11
  • 11
    • 0242663585 scopus 로고    scopus 로고
    • Cellular Basis of Ectopic Germinal Center Formation and Autoantibody Production in the Target Organ of Patients With Sjögren's Syndrome
    • DOI 10.1002/art.11311
    • Salomonsson, S., M. V. Jonsson, K. Skarstein, K. A. Brokstad, P. Hjelmström, M. Wahren-Herlenius, and R. Jonsson. 2003. Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren's syndrome. Arthritis Rheum. 48: 3187-3201. (Pubitemid 37409331)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.11 , pp. 3187-3201
    • Salomonsson, S.1    Jonsson, M.V.2    Skarstein, K.3    Brokstad, K.A.4    Hjelmstrom, P.5    Wahren-Herlenius, M.6    Jonsson, R.7
  • 12
    • 65449138304 scopus 로고    scopus 로고
    • Ectopic germinal centers are rare in Sjogren's syndrome salivary glands and do not exclude autoreactive B cells
    • Le Pottier, L., V. Devauchelle, A. Fautrel, C. Daridon, A. Saraux, P. Youinou, and J. O. Pers. 2009. Ectopic germinal centers are rare in Sjogren's syndrome salivary glands and do not exclude autoreactive B cells. J. Immunol. 182: 3540-3547.
    • (2009) J. Immunol. , vol.182 , pp. 3540-3547
    • Le Pottier, L.1    Devauchelle, V.2    Fautrel, A.3    Daridon, C.4    Saraux, A.5    Youinou, P.6    Pers, J.O.7
  • 13
    • 79959799977 scopus 로고    scopus 로고
    • Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjögren's syndrome
    • Theander, E., L. Vasaitis, E. Baecklund, G. Nordmark, G. Warfvinge, R. Liedholm, K. Brokstad, R. Jonsson, and M. V. Jonsson. 2011. Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjögren's syndrome. Ann. Rheum. Dis. 70: 1363-1368.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 1363-1368
    • Theander, E.1    Vasaitis, L.2    Baecklund, E.3    Nordmark, G.4    Warfvinge, G.5    Liedholm, R.6    Brokstad, K.7    Jonsson, R.8    Jonsson, M.V.9
  • 14
    • 61849115693 scopus 로고    scopus 로고
    • Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice
    • Gatumu, M. K., K. Skarstein, A. Papandile, J. L. Browning, R. A. Fava, and A. I. Bolstad. 2009. Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice. Arthritis Res. Ther. 11: R24.
    • (2009) Arthritis Res. Ther. , vol.11
    • Gatumu, M.K.1    Skarstein, K.2    Papandile, A.3    Browning, J.L.4    Fava, R.A.5    Bolstad, A.I.6
  • 15
    • 84866537988 scopus 로고    scopus 로고
    • Ectopic lymphoid neogenesis and lymphoid chemokines in Sjogren's syndrome: At the interplay between chronic inflammation, autoimmunity and lymphomagenesis
    • Bombardieri, M., and C. Pitzalis. 2012. Ectopic lymphoid neogenesis and lymphoid chemokines in Sjogren's syndrome: at the interplay between chronic inflammation, autoimmunity and lymphomagenesis. Curr. Pharm. Biotechnol. 13: 1989-1996.
    • (2012) Curr. Pharm. Biotechnol. , vol.13 , pp. 1989-1996
    • Bombardieri, M.1    Pitzalis, C.2
  • 16
    • 0038685647 scopus 로고    scopus 로고
    • Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice
    • DOI 10.1038/sj.gt.3301986
    • Smeets, R. L., F. A. van de Loo, O. J. Arntz, M. B. Bennink, L. A. Joosten, and W. B. van den Berg. 2003. Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice. Gene Ther. 10: 1004-1011. (Pubitemid 36722490)
    • (2003) Gene Therapy , vol.10 , Issue.12 , pp. 1004-1011
    • Smeets, R.L.1    Van De, L.F.A.J.2    Arntz, O.J.3    Benninck, M.B.4    Joosten, L.A.B.5    Van Den, B.W.B.6
  • 17
    • 33745158157 scopus 로고
    • A simple method for estimating fifty percent endpoints
    • Reed, L. J., and H. Muench. 1938. A simple method for estimating fifty percent endpoints. Am. J. Hyg. 27: 493-497.
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 18
    • 78049505730 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase increases secretion from inflamed salivary glands
    • Correia, P. N., G. H. Carpenter, K. L. Paterson, and G. B. Proctor. 2010. Inducible nitric oxide synthase increases secretion from inflamed salivary glands. Rheumatology (Oxford) 49: 48-56.
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 48-56
    • Correia, P.N.1    Carpenter, G.H.2    Paterson, K.L.3    Proctor, G.B.4
  • 19
    • 78649834967 scopus 로고    scopus 로고
    • Evolution of ectopic lymphoid neogenesis and in situ autoantibody production in autoimmune nonobese diabetic mice: Cellular and molecular characterization of tertiary lymphoid structures in pancreatic islets
    • Astorri, E., M. Bombardieri, S. Gabba, M. Peakman, P. Pozzilli, and C. Pitzalis. 2010. Evolution of ectopic lymphoid neogenesis and in situ autoantibody production in autoimmune nonobese diabetic mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islets. J. Immunol. 185: 3359-3368.
    • (2010) J. Immunol. , vol.185 , pp. 3359-3368
    • Astorri, E.1    Bombardieri, M.2    Gabba, S.3    Peakman, M.4    Pozzilli, P.5    Pitzalis, C.6
  • 20
    • 80053442737 scopus 로고    scopus 로고
    • Gene delivery in salivary glands: From the bench to the clinic
    • Samuni, Y., and B. J. Baum. 2011. Gene delivery in salivary glands: from the bench to the clinic. Biochim. Biophys. Acta 1812: 1515-1521.
    • (2011) Biochim. Biophys. Acta , vol.1812 , pp. 1515-1521
    • Samuni, Y.1    Baum, B.J.2
  • 21
    • 27744573075 scopus 로고    scopus 로고
    • Lymphotoxin-β receptor signaling is required for the homeostatic control of HEV differentiation and function
    • DOI 10.1016/j.immuni.2005.10.002, PII S1074761305003407
    • Browning, J. L., N. Allaire, A. Ngam-Ek, E. Notidis, J. Hunt, S. Perrin, and R. A. Fava. 2005. Lymphotoxin-beta receptor signaling is required for the homeostatic control of HEV differentiation and function. Immunity 23: 539-550. (Pubitemid 41587893)
    • (2005) Immunity , vol.23 , Issue.5 , pp. 539-550
    • Browning, J.L.1    Allaire, N.2    Ngam-Ek, A.3    Notidis, E.4    Hunt, J.5    Perrin, S.6    Fava, R.A.7
  • 22
    • 0033679060 scopus 로고    scopus 로고
    • BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis
    • Luther, S. A., T. Lopez, W. Bai, D. Hanahan, and J. G. Cyster. 2000. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis. Immunity 12: 471-481.
    • (2000) Immunity , vol.12 , pp. 471-481
    • Luther, S.A.1    Lopez, T.2    Bai, W.3    Hanahan, D.4    Cyster, J.G.5
  • 23
    • 0033579821 scopus 로고    scopus 로고
    • Lymphotoxin α/β and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen
    • DOI 10.1084/jem.189.2.403
    • Ngo, V. N., H. Korner, M. D. Gunn, K. N. Schmidt, D. S. Riminton, M. D. Cooper, J. L. Browning, J. D. Sedgwick, and J. G. Cyster. 1999. Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J. Exp. Med. 189: 403-412. (Pubitemid 29063261)
    • (1999) Journal of Experimental Medicine , vol.189 , Issue.2 , pp. 403-412
    • Ngo, V.N.1    Korner, H.2    Gunn, M.D.3    Schmidt, K.N.4    Riminton, D.S.5    Cooper, M.D.6    Browning, J.L.7    Sedgwick, J.D.8    Cyster, J.G.9
  • 24
    • 33646343709 scopus 로고    scopus 로고
    • Antimuscarinic antibodies in primary Sjögren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells
    • DOI 10.1002/art.21764
    • Dawson, L. J., J. Stanbury, N. Venn, B. Hasdimir, S. N. Rogers, and P. M. Smith. 2006. Antimuscarinic antibodies in primary Sjögren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells. Arthritis Rheum. 54: 1165-1173. (Pubitemid 43672929)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.4 , pp. 1165-1173
    • Dawson, L.J.1    Stanbury, J.2    Venn, N.3    Hasdimir, B.4    Rogers, S.N.5    Smith, P.M.6
  • 25
    • 0033136636 scopus 로고    scopus 로고
    • New concepts for the development of autoimmune exocrinopathy derived from studies with the NOD mouse model
    • DOI 10.1016/S0003-9969(99)00045-X, PII S000399699900045X
    • Humphreys-Beher, M. G., and A. B. Peck. 1999. New concepts for the development of autoimmune exocrinopathy derived from studies with the NOD mouse model. Arch. Oral Biol. 44(Suppl. 1): S21-S25. (Pubitemid 29292936)
    • (1999) Archives of Oral Biology , vol.44 , Issue.SUPPL. 1
    • Humphreys-Beher, M.G.1    Peck, A.B.2
  • 26
    • 0030890162 scopus 로고    scopus 로고
    • Characterisation of follicular dendritic cells in labial salivary glands of patients with primary Sjogren syndrome: Comparison with tonsillar lymphoid follicles
    • Aziz, K. E., P. J. McCluskey, and D. Wakefield. 1997. Characterisation of follicular dendritic cells in labial salivary glands of patients with primary Sjögren syndrome: comparison with tonsillar lymphoid follicles. Ann. Rheum. Dis. 56: 140-143. (Pubitemid 27119611)
    • (1997) Annals of the Rheumatic Diseases , vol.56 , Issue.2 , pp. 140-143
    • Aziz, K.E.1    McCluskey, P.J.2    Wakefield, D.3
  • 27
    • 13444262768 scopus 로고    scopus 로고
    • Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: Relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate
    • Bombardieri, M., F. Barone, V. Pittoni, C. Alessandri, P. Conigliaro, M. C. Blades, R. Priori, I. B. McInnes, G. Valesini, and C. Pitzalis. 2004. Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Res. Ther. 6: R447-R456.
    • (2004) Arthritis Res. Ther. , vol.6
    • Bombardieri, M.1    Barone, F.2    Pittoni, V.3    Alessandri, C.4    Conigliaro, P.5    Blades, M.C.6    Priori, R.7    McInnes, I.B.8    Valesini, G.9    Pitzalis, C.10
  • 28
    • 0032169223 scopus 로고    scopus 로고
    • Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjogren's syndrome
    • Stott, D. I., F. Hiepe, M. Hummel, G. Steinhauser, and C. Berek. 1998. Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome. J. Clin. Invest. 102: 938-946. (Pubitemid 28419239)
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.5 , pp. 938-946
    • Stott, D.I.1    Hiepe, F.2    Hummel, M.3    Steinhauser, G.4    Berek, C.5
  • 29
    • 0032433666 scopus 로고    scopus 로고
    • Murine cytomegalovirus induces a Sjogren's syndrome-like disease in C57B1/6-lpr/lpr mice
    • DOI 10.1002/1529-0131(199812)41:12<2175::AID-ART12>3.0.CO;2-I
    • Fleck, M., E. R. Kern, T. Zhou, B. Lang, and J. D. Mountz. 1998. Murine cytomegalovirus induces a Sjögren's syndrome-like disease in C57Bl/6-lpr/lpr mice. Arthritis Rheum. 41: 2175-2184. (Pubitemid 29009375)
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.12 , pp. 2175-2184
    • Fleck, M.1    Kern, E.R.2    Zhou, T.3    Lang, B.4    Mountz, J.D.5
  • 30
    • 0035052164 scopus 로고    scopus 로고
    • Treatment of chronic sialadenitis in a murine model of Sjögren's syndrome by local fasL gene transfer
    • DOI 10.1002/1529-0131(200104)44:4<964::AID-ANR154>3.0.CO;2-5
    • Fleck, M., H. G. Zhang, E. R. Kern, H. C. Hsu, U. Müller-Ladner, and J. D. Mountz. 2001. Treatment of chronic sialadenitis in a murine model of Sjögren's syndrome by local fasL gene transfer. Arthritis Rheum. 44: 964-973. (Pubitemid 32319790)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.4 , pp. 964-973
    • Fleck, M.1    Zhang, H.-G.2    Kern, E.R.3    Hsu, H.-C.4    Muller-Ladner, U.5    Mountz, J.D.6
  • 31
    • 78650318494 scopus 로고    scopus 로고
    • Pathogenic effect of interleukin-17A in induction of Sjögren's syndromelike disease using adenovirus-mediated gene transfer
    • Nguyen, C. Q., H. Yin, B. H. Lee, W. C. Carcamo, J. A. Chiorini, and A. B. Peck. 2010. Pathogenic effect of interleukin-17A in induction of Sjögren's syndromelike disease using adenovirus-mediated gene transfer. Arthritis Res. Ther. 12: R220.
    • (2010) Arthritis Res. Ther. , vol.12
    • Nguyen, C.Q.1    Yin, H.2    Lee, B.H.3    Carcamo, W.C.4    Chiorini, J.A.5    Peck, A.B.6
  • 32
    • 77956175900 scopus 로고    scopus 로고
    • New insights into the development of lymphoid tissues
    • van de Pavert, S. A., and R. E. Mebius. 2010. New insights into the development of lymphoid tissues. Nat. Rev. Immunol. 10: 664-674.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 664-674
    • Van De Pavert, S.A.1    Mebius, R.E.2
  • 33
    • 33749425111 scopus 로고    scopus 로고
    • Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid
    • DOI 10.1172/JCI28993
    • Marinkovic, T., A. Garin, Y. Yokota, Y. X. Fu, N. H. Ruddle, G. C. Furtado, and S. A. Lira. 2006. Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid. J. Clin. Invest. 116: 2622-2632. (Pubitemid 44511626)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.10 , pp. 2622-2632
    • Marinkovic, T.1    Garin, A.2    Yokota, Y.3    Fu, Y.-X.4    Ruddle, N.H.5    Furtado, G.C.6    Lira, S.A.7
  • 34
    • 44449140526 scopus 로고    scopus 로고
    • CXCL13, CCL21, and CXCL12 expression in salivary glands of patients with Sjogren's syndrome and MALT lymphoma: Association with reactive and malignant areas of lymphoid organization
    • Barone, F., M. Bombardieri, M. M. Rosado, P. R. Morgan, S. J. Challacombe, S. De Vita, R. Carsetti, J. Spencer, G. Valesini, and C. Pitzalis. 2008. CXCL13, CCL21, and CXCL12 expression in salivary glands of patients with Sjogren's syndrome and MALT lymphoma: association with reactive and malignant areas of lymphoid organization. J. Immunol. 180: 5130-5140.
    • (2008) J. Immunol. , vol.180 , pp. 5130-5140
    • Barone, F.1    Bombardieri, M.2    Rosado, M.M.3    Morgan, P.R.4    Challacombe, S.J.5    De Vita, S.6    Carsetti, R.7    Spencer, J.8    Valesini, G.9    Pitzalis, C.10
  • 35
    • 42249089348 scopus 로고    scopus 로고
    • The salivary glands as a privileged site of cytomegalovirus immune evasion and persistence
    • Campbell, A. E., V. J. Cavanaugh, and J. S. Slater. 2008. The salivary glands as a privileged site of cytomegalovirus immune evasion and persistence. Med. Microbiol. Immunol. (Berl.) 197: 205-213.
    • (2008) Med. Microbiol. Immunol. (Berl.) , vol.197 , pp. 205-213
    • Campbell, A.E.1    Cavanaugh, V.J.2    Slater, J.S.3
  • 37
    • 77955160246 scopus 로고    scopus 로고
    • Pathogenesis of Sjögren's syndrome and therapeutic consequences
    • Mariette, X., and J. E. Gottenberg. 2010. Pathogenesis of Sjögren's syndrome and therapeutic consequences. Curr. Opin. Rheumatol. 22: 471-477.
    • (2010) Curr. Opin. Rheumatol. , vol.22 , pp. 471-477
    • Mariette, X.1    Gottenberg, J.E.2
  • 38
    • 84862490927 scopus 로고    scopus 로고
    • Pathogenesis of Sjögren's syndrome: What we know and what we should learn
    • Tzioufas, A. G., E. K. Kapsogeorgou, and H. M. Moutsopoulos. 2012. Pathogenesis of Sjögren's syndrome: what we know and what we should learn. J. Autoimmun. 39: 4-8.
    • (2012) J. Autoimmun. , vol.39 , pp. 4-8
    • Tzioufas, A.G.1    Kapsogeorgou, E.K.2    Moutsopoulos, H.M.3
  • 40
    • 0033603340 scopus 로고    scopus 로고
    • Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
    • Muramatsu, M., V. S. Sankaranand, S. Anant, M. Sugai, K. Kinoshita, N. O. Davidson, and T. Honjo. 1999. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J. Biol. Chem. 274: 18470-18476.
    • (1999) J. Biol. Chem. , vol.274 , pp. 18470-18476
    • Muramatsu, M.1    Sankaranand, V.S.2    Anant, S.3    Sugai, M.4    Kinoshita, K.5    Davidson, N.O.6    Honjo, T.7
  • 41
    • 14244268367 scopus 로고    scopus 로고
    • Selecting B cells and plasma cells to memory
    • DOI 10.1084/jem.20050218
    • Dörner, T., and A. Radbruch. 2005. Selecting B cells and plasma cells to memory. J. Exp. Med. 201: 497-499. (Pubitemid 40289538)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.4 , pp. 497-499
    • Dorner, T.1    Radbruch, A.2
  • 42
    • 1542513365 scopus 로고    scopus 로고
    • Textbook Germinal Centers?
    • Manser, T. 2004. Textbook germinal centers? J. Immunol. 172: 3369-3375. (Pubitemid 38337913)
    • (2004) Journal of Immunology , vol.172 , Issue.6 , pp. 3369-3375
    • Manser, T.1
  • 46
    • 34247181001 scopus 로고    scopus 로고
    • Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI
    • DOI 10.1038/ni1434, PII NI1434
    • Xu, W., B. He, A. Chiu, A. Chadburn, M. Shan, M. Buldys, A. Ding, D. M. Knowles, P. A. Santini, and A. Cerutti. 2007. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat. Immunol. 8: 294-303. (Pubitemid 46745379)
    • (2007) Nature Immunology , vol.8 , Issue.3 , pp. 294-303
    • Xu, W.1    He, B.2    Chiu, A.3    Chadburn, A.4    Shan, M.5    Buldys, M.6    Ding, A.7    Knowles, D.M.8    Santini, P.A.9    Cerutti, A.10
  • 47
    • 80052502019 scopus 로고    scopus 로고
    • A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells
    • Bombardieri, M., N. W. Kam, F. Brentano, K. Choi, A. Filer, D. Kyburz, I. B. McInnes, S. Gay, C. Buckley, and C. Pitzalis. 2011. A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells. Ann. Rheum. Dis. 70: 1857-1865.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 1857-1865
    • Bombardieri, M.1    Kam, N.W.2    Brentano, F.3    Choi, K.4    Filer, A.5    Kyburz, D.6    McInnes, I.B.7    Gay, S.8    Buckley, C.9    Pitzalis, C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.