Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome

Journal of Clinical Investigation

Volumn 109, Issue 1, 2002, Pages 59-68

  Groom, Joanna ^a   Kalled, Susan L ^b   Cutler, Anne H ^b   Olson, Carl ^b   Woodcock, Stephen A ^b   Schneider, Pascal ^c   Tschopp, Jurg ^c   Cachero, Teresa G ^b   Batten, Marcel ^a   Wheway, Julie ^a   Mauri, Davide ^d   Cavill, Dana ^e   Gordon, Tom P ^d   Mackay, Charles R ^a   Mackay, Fabienne ^a  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b BIOGEN   (United States)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d Apotech Corporation   (Switzerland)

^e FLINDERS MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE ACTIVATION; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL SUBPOPULATION; CELL SURVIVAL; DISEASE ASSOCIATION; MONONUCLEAR CELL; MOUSE; NONHUMAN; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0036144353     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI0214121     Document Type: Article

References (50)

1. Sjögren's syndrome
2. Sjögren's syndrome
3. Occurrence of antibody to salivary duct epithelium in Sjögren's disease, rheumatoid arthritis, and other arthritides. A clinical and laboratory study
4. Identification of α-fodrin as a candidate autoantigen in primary Sjögren's syndrome
5. Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome
6. Synthesis and release of B-lymphocyte stimulator from myeloid cells
7. APRIL and BAFF connect autoimmunity and cancer
8. Decoy receptors thwart B cells
9. Lymphocyte survival - Ignorance is BLyS
10. The role of TALL-1 and APRIL in immune regulation
11. APRIL and TALL-1 and receptors BCMA and TACI: System for regulating humoral immunity
12. Tumor necrosis Factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS
13. B cell maturation protein is a receptor for the tumor necrosis factor family member TALL-1
14. BAFF-R, a novel TNF receptor that specifically interacts with BAFF
15. NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor super-family
16. TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation
17. Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
18. BAFF binds to the TNF receptor-like molecule BCMA and is important for maintaining the peripheral B cell population
19. Attenuation of apoptosis underlies B lymphocyte stimulatot enhancement of humoral immune response
20. BAFF mediates survival of peripheral immature B lymphocytes
21. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
22. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: Impaired B cell maturation in mice lacking BLyS
23. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
24. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
25. Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk
26. A role for B lymphocyte stimulator in systemic lupus erythematosus
27. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
28. To B or not to B: TNF family signalling in lymphocytes
29. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
30. TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice
31. BAFF, a novel ligand of the tumor necrosis factor (TNF) family, stimulates B-cell growth
32. Induction of experimental autoallergic sialadenitis
33. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
34. The 1982 revised criteria for the classification of systemic lupus erythemarosus
35. Preliminary criteria for the classification of Sjögren syndrome. Results of a prospective concerted action supported by the European Community
36. Labial salivary gland biopsy in Sjögren's disease
37. Molecular chaperones are targets of autoimmunity in Ro(SS-A) immune mice
38. CD43 (S7) expression identifies peripheral B cell subsets
39. CD1 expression defines subsets of follicular and marginal zone B cells in the spleen β2-microglobulin-dependent and independent forms
40. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
41. null mice reveals a role for autoantibodies in the loss of secretory function of exocrine tissue in Sjögren's syndrome
42. Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
43. Proapoptotic Bcl-2 relative Bim required For certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
44. A role for CD1 in the pathogenesis of lupus in NZB/NZW mice
45. Expansion and activation of a population, of autoreactive marginal zone B cells in a model of estrogen-induced lupus
46. T-independent immune response: New aspects of B cell biology
47. Clinico-pathological factors relating malignant lymphoma with Sjögren's syndrome
48. B1 cells: Similarities and differences with other B cell subsets
49. Determinant spreading: Lessons from animal models and human disease
50. Mucosa-associated lymphoid tissue lymphomas