Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

Cell

Volumn 171, Issue 6, 2017, Pages 1397-1410.e14

  Elosegui Artola, Alberto ^a   Andreu, Ion ^b,c   Beedle, Amy E M ^d,e   Lezamiz, Ainhoa ^d,e   Uroz, Marina ^a   Kosmalska, Anita J ^a,f   Oria, Roger ^a,f   Kechagia, Jenny Z ^a   Rico Lastres, Palma ^d,e   Le Roux, Anabel Lise ^a   Shanahan, Catherine M ^e   Trepat, Xavier ^a,f,g,h   Navajas, Daniel ^a,f,i   Garcia Manyes, Sergi ^d,e   Roca Cusachs, Pere ^a,f  

^a INSTITUTE FOR BIOENGINEERING OF CATALONIA IBEC   (Spain)

^b MONDRAGON UNIVERSITY   (Spain)

^c CEIT   (Spain)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF BARCELONA   (Spain)

^g INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^h BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

ⁱ INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

atomic force microscopy; Hippo pathway; mechanosensing; mechanotransduction; molecular mechanical stability; nuclear mechanics; nuclear pores; nuclear transport; rigidity sensing; transcription regulation

Indexed keywords

PROTEIN YAP; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP PROTEIN, MOUSE; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOSKELETON; FOCAL ADHESION; FORCE; HIPPO SIGNALING; HUMAN; HUMAN CELL; MECHANICAL RESISTANCE; MECHANOTRANSDUCTION; MOLECULAR MECHANICS; NUCLEAR IMPORT; NUCLEAR PORE; NUCLEOCYTOPLASMIC TRANSPORT; PHYSICAL PARAMETERS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STABILITY; PROTEIN TRANSPORT; TRANSCRIPTION REGULATION; ANIMAL; BIOMECHANICS; GENETIC TRANSCRIPTION; METABOLISM; MOUSE; TUMOR CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BIOMECHANICAL PHENOMENA; CELL LINE, TUMOR; CELL NUCLEUS; HUMANS; MICE; NUCLEAR PORE; PHOSPHOPROTEINS; TRANSCRIPTION, GENETIC;

EID: 85032590480     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.10.008     Document Type: Article

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