YAP nuclear localization in the absence of cell-cell contact is mediated by a filamentous actin-dependent, Myosin IIand Phospho-YAP-independent pathway during extracellular matrix mechanosensing

Journal of Biological Chemistry

Volumn 291, Issue 12, 2016, Pages 6096-6110

  Das, Arupratan ^a,b   Fischer, Robert S ^a   Pan, Duojia ^b   Waterman, Clare M ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; CELLS; CYTOLOGY; MUSCLE; PHOSPHORYLATION; STIFFNESS; STIFFNESS MATRIX;

ABSENCE OF CELLS; CELL-CELL CONTACT; EXTRACELLULAR MATRICES; LATTER MECHANISM; MECHANICAL ENVIRONMENT; MECHANOTRANSDUCTION; NUCLEAR LOCALIZATION; PHYSIOLOGICAL ENVIRONMENT;

PROTEINS;

F ACTIN; INTEGRIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN II; PEPTIDES AND PROTEINS; PROTEIN YAP; SERINE; UNCLASSIFIED DRUG; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP PROTEIN, MOUSE;

ARTICLE; CELL CONTACT; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSKELETON; EXTRACELLULAR MATRIX; MECHANOTRANSDUCTION; MUSCLE CONTRACTILITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ACTIN FILAMENT; ACTIVE TRANSPORT; ANIMAL; CELL ADHESION; CELL CULTURE; HUMAN; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; TUMOR CELL LINE;

ACTIN CYTOSKELETON; ACTIVE TRANSPORT, CELL NUCLEUS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL NUCLEUS; CELLS, CULTURED; CYTOSKELETON; EXTRACELLULAR MATRIX; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MICE; MYOSIN TYPE II; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84964744532     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.708313     Document Type: Article

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