Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

Nature Cell Biology

Volumn 18, Issue 5, 2016, Pages 540-548

  Elosegui Artola, Alberto ^a   Oria, Roger ^a,b   Chen, Yunfeng ^c,d   Kosmalska, Anita ^a,b   Pérez González, Carlos ^a,b   Castro, Natalia ^a   Zhu, Cheng ^c,d   Trepat, Xavier ^a,b,e,f   Roca Cusachs, Pere ^a,b  

^a INSTITUTE FOR BIOENGINEERING OF CATALONIA IBEC   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^d GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^f BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; FIBRONECTIN; INTEGRIN; MYOSIN; REGULATOR PROTEIN; TALIN; UNCLASSIFIED DRUG; VINCULIN; YAP PROTEIN; FOCAL ADHESION KINASE; PHOSPHOPROTEIN; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BIOCHEMISTRY; CELL ADHESION; CELL FUNCTION; CELL GROWTH; CELL NUCLEUS; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR MATRIX; FIBROBLAST; FORCE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN UNFOLDING; QUANTITATIVE ANALYSIS; RIGIDITY; SIGNAL TRANSDUCTION; YOUNG MODULUS; ANIMAL; BIOMECHANICS; CYTOSKELETON; MECHANOTRANSDUCTION; METABOLISM; PHOSPHORYLATION; PROTEIN TRANSPORT; STRESS FIBER;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BIOMECHANICAL PHENOMENA; CELL ADHESION; CELL NUCLEUS; CYTOSKELETON; EXTRACELLULAR MATRIX; FIBRONECTINS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; INTEGRINS; MECHANOTRANSDUCTION, CELLULAR; MICE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; STRESS FIBERS; TALIN; VINCULIN;

EID: 84963600077     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3336     Document Type: Article

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