Isopeptide bonds block the mechanical extension of pili in pathogenic Streptococcus pyogenes

Journal of Biological Chemistry

Volumn 285, Issue 15, 2010, Pages 11235-11242

  Alegre Cebollada, Jorge ^a   Badilla, Carmen L ^a   Fernández, Julio M ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOFILM FORMATION; C-TERMINAL DOMAINS; FIBROUS STRUCTURES; HOST CELLS; HUMAN PATHOGENS; ISOPEPTIDE BOND; MECHANICAL FINGERPRINT; MECHANICAL FORCE; MODULAR PROTEINS; N-TERMINAL DOMAINS; PATHOGENIC BACTERIUM; POLYPROTEINS; SINGLE MOLECULE FORCE SPECTROSCOPY; STREPTOCOCCUS PYOGENES; X-RAY STRUCTURE;

BACTERIA; MECHANICAL PROPERTIES;

PROTEINS;

CONNECTIN; FIBRONECTIN; PILIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BACTERIUM PILUS; BIOFILM; CARBOXY TERMINAL SEQUENCE; CHEMICAL BOND; COLONY FORMATION; CONTROLLED STUDY; COVALENT BOND; GRAM POSITIVE BACTERIUM; HOST CELL; MUTAGENESIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STRUCTURE; STREPTOCOCCUS PYOGENES;

BACTERIAL PHYSIOLOGICAL PHENOMENA; BIOPHYSICS; CRYSTALLOGRAPHY, X-RAY; FIMBRIAE, BACTERIAL; HYDROGEN BONDING; MICROSCOPY, ATOMIC FORCE; MODELS, BIOLOGICAL; MUTATION; PEPTIDES; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; STREPTOCOCCUS PYOGENES; STRESS, MECHANICAL;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOCOCCUS PYOGENES;

EID: 77951250536     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.102962     Document Type: Article

References (49)

1. Cunningham, M. W. (2008) Adv. Exp. Med. Biol. 609, 29-42
2. Manetti, A. G., Zingaretti, C., Falugi, F., Capo, S., Bombaci, M., Bagnoli, F., Gambellini, G., Bensi, G., Mora, M., Edwards, A. M., Musser, J. M., Graviss, E. A., Telford, J. L., Grandi, G., and Margarit, I. (2007) Mol. Microbiol. 64, 968-983
3. Abbot, E. L., Smith, W. D., Siou, G. P., Chiriboga, C., Smith, R. J., Wilson, J. A., Hirst, B. H., and Kehoe, M. A. (2007) Cell Microbiol. 9, 1822-1833
4. Proft, T., and Baker, E. N. (2009) Cell Mol. Life Sci. 66, 613-635
5. Craig, L., Pique, M. E., and Tainer, J. A. (2004) Nat. Rev. Microbiol. 2, 363-378
6. Mandlik, A., Swierczynski, A., Das, A., and Ton-That, H. (2008) Trends Microbiol. 16, 33-40
7. Nallapareddy, S. R., Singh, K. V., Sillanpää, J., Garsin, D. A., Höök, M., Erlandsen, S. L., and Murray, B. E. (2006) J. Clin. Invest. 116, 2799-2807
8. Mora, M., Bensi, G., Capo, S., Falugi, F., Zingaretti, C., Manetti, A. G., Maggi, T., Taddei, A. R., Grandi, G., and Telford, J. L. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 15641-15646
9. Budzik, J. M., and Schneewind, O. (2006) J. Clin. Invest. 116, 2582-2584
10. Maier, B., Potter, L., So, M., Long, C. D., Seifert, H. S., and Sheetz, M. P. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 16012-16017
11. Biais, N., Ladoux, B., Higashi, D., So, M., and Sheetz, M. (2008) PLoS Biol. 6, e87
12. Yeates, T. O., and Clubb, R. T. (2007) Science 318, 1558-1559
13. Ton-That, H., and Schneewind, O. (2003) Mol. Microbiol. 50, 1429-1438
14. Scott, J. R., and Zähner, D. (2006) Mol. Microbiol. 62, 320-330
15. Telford, J. L., Barocchi, M. A., Margarit, I., Rappuoli, R., and Grandi, G. (2006) Nat. Rev. Microbiol. 4, 509-519
16. Swaminathan, A., Mandlik, A., Swierczynski, A., Gaspar, A., Das, A., and Ton-That, H. (2007) Mol. Microbiol. 66, 961-974
17. Hilleringmann, M., Ringler, P., Müller, S. A., De Angelis, G., Rappuoli, R., Ferlenghi, I., and Engel, A. (2009) EMBO J. 28, 3921-3930
18. Rief, M., Gautel, M., Oesterhelt, F., Fernandez, J. M., and Gaub, H. E. (1997) Science 276, 1109-1112
19. Oberhauser, A. F., Badilla-Fernandez, C., Carrion-Vazquez, M., and Fernandez, J. M. (2002) J. Mol. Biol. 319, 433-447
20. Li, H., Linke, W. A., Oberhauser, A. F., Carrion-Vazquez, M., Kerkvliet, J. G., Lu, H., Marszalek, P. E., and Fernandez, J. M. (2002) Nature 418, 998-1002
21. Kang, H. J., Coulibaly, F., Clow, F., Proft, T., and Baker, E. N. (2007) Science 318, 1625-1628
22. Kang, H. J., and Baker, E. N. (2009) J. Biol. Chem. 284, 20729-20737
23. Kang, H. J., Paterson, N. G., Gaspar, A. H., Ton-That, H., and Baker, E. N. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 16967-16971
24. Li, H., and Fernandez, J. M. (2003) J. Mol. Biol. 334, 75-86
25. Carrion-Vazquez, M., Oberhauser, A. F., Fowler, S. B., Marszalek, P. E., Broedel, S. E., Clarke, J., and Fernandez, J. M. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 3694-3699
26. Florin, E. L., Rief, M., Lehmann, H., Ludwig, M., Dornmair, C., Moy, V. T., and Gaub, H. E. (1995) Biosens. Bioelectron. 10, 895-901
27. Bustamante, C., Marko, J. F., Siggia, E. D., and Smith, S. (1994) Science 265, 1599-1600
28. Dougan, L., Li, J., Badilla, C. L., Berne, B. J., and Fernandez, J. M. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 12605-12610
29. Carrion-Vazquez, M., Oberhauser, A. F., Fisher, T. E., Marszalek, P. E., Li, H., and Fernandez, J. M. (2000) Prog. Biophys. Mol. Biol. 74, 63-91
30. Perez-Jimenez, R., Garcia-Manyes, S., Ainavarapu, S. R., and Fernandez, J. M. (2006) J. Biol. Chem. 281, 40010-40014
31. Improta, S., Krueger, J. K., Gautel, M., Atkinson, R. A., Lefèvre, J. F., Moulton, S., Trewhella, J., and Pastore, A. (1998) J. Mol. Biol. 284, 761-777
32. Ainavarapu, S. R., Brujic, J., Huang, H. H., Wiita, A. P., Lu, H., Li, L., Walther, K. A., Carrion-Vazquez, M., Li, H., and Fernandez, J. M. (2007) Biophys. J. 92, 225-233
33. Oberhauser, A. F., Hansma, P. K., Carrion-Vazquez, M., and Fernandez, J. M. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 468-472
34. Garcia-Manyes, S., Brujić, J., Badilla, C. L., and Fernández, J. M. (2007) Biophys. J. 93, 2436-2446
35. Grandbois, M., Beyer, M., Rief, M., Clausen-Schaumann, H., and Gaub, H. E. (1999) Science 283, 1727-1730
36. Marszalek, P. E., Lu, H., Li, H., Carrion-Vazquez, M., Oberhauser, A. F., Schulten, K., and Fernandez, J. M. (1999) Nature 402, 100-103
37. Forman, J. R., and Clarke, J. (2007) Curr. Opin. Struct. Biol. 17, 58-66
38. Lauer, P., Rinaudo, C. D., Soriani, M., Margarit, I., Maione, D., Rosini, R., Taddei, A. R., Mora, M., Rappuoli, R., Grandi, G., and Telford, J. L. (2005) Science 309, 105
39. LeMieux, J., Hava, D. L., Basset, A., and Camilli, A. (2006) Infect Immun. 74, 2453-2456
40. Mishra, A., Das, A., Cisar, J. O., and Ton-That, H. (2007) J. Bacteriol. 189, 3156-3165
41. Budzik, J. M., Marraffini, L. A., Souda, P., Whitelegge, J. P., Faull, K. F., and Schneewind, O. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 10215-10220
42. Budzik, J. M., Poor, C. B., Faull, K. F., Whitelegge, J. P., He, C., and Schneewind, O. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 19992-19997
43. Sikora, M., Sulkowska, J. I., and Cieplak, M. (2009) PLoS Comput. Biol. 5, e1000547
44. Jass, J., Schedin, S., Fällman, E., Ohlsson, J., Nilsson, U. J., Uhlin, B. E., and Axner, O. (2004) Biophys. J. 87, 4271-4283
45. Fällman, E., Schedin, S., Jass, J., Uhlin, B. E., and Axner, O. (2005) EMBO Rep. 6, 52-56
46. Miller, E., Garcia, T., Hultgren, S., and Oberhauser, A. F. (2006) Biophys. J. 91, 3848-3856
47. Touhami, A., Jericho, M. H., Boyd, J. M., and Beveridge, T. J. (2006) J. Bacteriol. 188, 370-377
48. Oberhauser, A. F., Marszalek, P. E., Erickson, H. P., and Fernandez, J. M. (1998) Nature 393, 181-185
49. Humphrey, W., Dalke, A., and Schulten, K. (1996) J. Mol. Graph. 14, 33-38