Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts

FASEB Journal

Volumn 28, Issue 9, 2014, Pages 3906-3918

  Ferrera, Denise ^a   Canale, Claudio ^a   Marotta, Roberto ^a   Mazzaro, Nadia ^a   Gritti, Marta ^b   Mazzanti, Michele ^b   Capellari, Sabina ^c,d   Cortelli, Pietro ^c,d   Gasparini, Laura ^a  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c BELLARIA HOSPITAL   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

ADLD; Atomic force microscopy; Human fibroblasts; Nuclear lamina; Nucleus

Indexed keywords

LAMIN B; LAMIN B1 PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; LAMIN B1; SMALL INTERFERING RNA;

ADULT; ANIMAL EXPERIMENT; ARTICLE; AUTOSOMAL DOMINANT LEUKODYSTROPHY; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE DUPLICATION; GENE OVEREXPRESSION; HEK293 CELL LINE; HUMAN; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; IN VITRO STUDY; ION PERMEABILITY; LEUKODYSTROPHY; MOUSE; NONHUMAN; NUCLEAR LAMINA; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKIN BIOPSY; SKIN FIBROBLAST; SOMATIC CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; CASE CONTROL STUDY; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; COMPARATIVE STUDY; CYTOLOGY; FEMALE; FIBROBLAST; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; MALE; MAMMALIAN EMBRYO; METABOLISM; MIDDLE AGED; PATCH CLAMP TECHNIQUE; PATHOLOGY; PELIZAEUS MERZBACHER DISEASE; PHENOTYPE; SKIN; WESTERN BLOTTING;

ADULT; ANIMALS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CELL PROLIFERATION; CELLS, CULTURED; EMBRYO, MAMMALIAN; FEMALE; FIBROBLASTS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LAMIN TYPE B; MALE; MICE; MIDDLE AGED; PATCH-CLAMP TECHNIQUES; PELIZAEUS-MERZBACHER DISEASE; PHENOTYPE; RNA, SMALL INTERFERING; SKIN;

EID: 84907190414     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-247635     Document Type: Article

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