Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Nature Materials

Volumn 15, Issue 3, 2016, Pages 326-334

  Chaudhuri, Ovijit ^a,b,c   Gu, Luo ^a,b   Klumpers, Darinka ^a,b,d   Darnell, Max ^a,b   Bencherif, Sidi A ^a,b   Weaver, James C ^b   Huebsch, Nathaniel ^a,e   Lee, Hong Pyo ^c   Lippens, Evi ^b,f   Duda, Georg N ^f   Mooney, David J ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c Stanford University   (United States)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION; CELLS; CYTOLOGY; ELASTIC MODULI; FLOWCHARTING; HYDROGELS; LIGANDS; MUSCLE; STEM CELLS; STRESS RELAXATION; STRESSES;

DESIGN PARAMETERS; EXTRACELLULAR MATRICES; INITIAL ELASTIC MODULUS; KEY CHARACTERISTICS; LIGAND DENSITY; MESENCHYMAL STEM CELL; OSTEOGENIC DIFFERENTIATION; THREEDIMENSIONAL (3-D);

CELL CULTURE;

ALGINIC ACID; GLUCURONIC ACID; HEXURONIC ACID; HYDROGEL;

BIOMECHANICS; CELL CULTURE TECHNIQUE; CELL DIFFERENTIATION; CHEMISTRY; EXTRACELLULAR MATRIX; HUMAN; HYDROGEL; MECHANICAL STRESS; MESENCHYMAL STROMA CELL; PHYSIOLOGY;

ALGINATES; BIOMECHANICAL PHENOMENA; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; EXTRACELLULAR MATRIX; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; HYDROGELS; MESENCHYMAL STROMAL CELLS; STRESS, MECHANICAL;

EID: 84959521469     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nmat4489     Document Type: Article

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