The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target

PLoS Pathogens

Volumn 13, Issue 9, 2017, Pages

  Abere, Bizunesh ^a,b   Mamo, Tamrat M ^a   Hartmann, Silke ^a,b   Samarina, Naira ^a,b   Hage, Elias ^a,b   Rückert, Jessica ^a,b   Hotop, Sven Kevin ^b,c   Büsche, Guntram ^a   Schulz, Thomas F ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Center for Experimental and Clinical Infection Research   (Germany)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NON STRUCTURAL MEMBRANE PROTEIN K15; PEPTIDES AND PROTEINS; PLC GAMMA 1; PROTEIN KINASE B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; K15 PROTEIN, HUMAN HERPESVIRUS 8; VIRAL PROTEIN;

ARTICLE; FLOTATION; GENE; GENE DELETION; GENETIC TRANSFECTION; HUMAN; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNOFLUORESCENCE TEST; K15 GENE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VIRAL GENE DELIVERY SYSTEM; VIRUS GENOME; VIRUS LATENCY; VIRUS REACTIVATION; VIRUS REPLICATION; WESTERN BLOTTING; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; KAPOSI SARCOMA; METABOLISM; PHYSIOLOGY; VIROLOGY; VIRUS ACTIVATION;

BLOTTING, WESTERN; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCKDOWN TECHNIQUES; HERPESVIRUS 8, HUMAN; HUMANS; SARCOMA, KAPOSI; VIRAL PROTEINS; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS REPLICATION;

EID: 85030473676     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006639     Document Type: Article

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