Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome contains a duplication of a long unique-region fragment within the terminal repeat region

Journal of Virology

Volumn 85, Issue 9, 2011, Pages 4612-4617

  Yakushko, Yuri ^a   Hackmann, Christian ^a   Günther, Thomas ^c   Rückert, Jessica ^a   Henke, Marc ^a   Koste, Lars ^a,d   Alkharsah, Khaled ^a   Bohne, Jens ^a   Grundhoff, Adam ^c   Schulz, Thomas F ^a   Henke Gendo, Cornelia ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Integrated Research and Treatment Center Transplantation   (Germany)

^c LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^d UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CONTROLLED STUDY; DNA SEQUENCE; GENE DUPLICATION; GENE LOCATION; HUMAN HERPESVIRUS 8; MUTAGENESIS; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; VIRUS GENE; VIRUS GENOME; VIRUS MUTATION;

CHROMOSOMES, ARTIFICIAL, BACTERIAL; DNA, VIRAL; HERPESVIRUS 8, HUMAN; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; SEGMENTAL DUPLICATIONS, GENOMIC; SEQUENCE ANALYSIS, DNA; TERMINAL REPEAT SEQUENCES;

BACTERIA (MICROORGANISMS); HUMAN HERPESVIRUS 8;

EID: 79955411474     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02068-10     Document Type: Article

References (28)

1. Adler, H., M. Messerle, M. Wagner, and U. H. Koszinowski. 2000. Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome. J. Virol. 74:6964-6974.
2. AuCoin, D. P., K. S. Colletti, Y. Xu, S. A. Cei, and G. S. Pari. 2002. Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains two functional lytic origins of DNA replication. J. Virol. 76:7890-7896.
3. Borst, E. M., C. Benkartek, and M. Messerle. 2007. Use of bacterial artificial chromosomes in generating targeted mutations in human and mouse cyto-megaloviruses. Curr. Protoc. Immunol. Chapter 10:Unit 10.32.
4. Borst, E. M., G. Hahn, U. H. Koszinowski, and M. Messerle. 1999. Cloning of the human cytomegalovirus (HCMV) genome as an infectious bacterial artificial chromosome in Escherichia coli: a new approach for construction of HCMV mutants. J. Virol. 73:8320-8329.
5. Cesarman, E., Y. Chang, P. S. Moore, J. W. Said, and D. M. Knowles. 1995. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N. Engl. J. Med. 332:1186-1191.
6. Chang, Y., et al. 1994. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266:1865-1869.
7. Delecluse, H. J., T. Hilsendegen, D. Pich, R. Zeidler, and W. Hammer-schmidt. 1998. Propagation and recovery of intact, infectious Epstein-Barr virus from prokaryotic to human cells. Proc. Natl. Acad. Sci. U. S. A. 95:8245-8250.
8. Estep, R. D., M. F. Powers, B. K. Yen, H. Li, and S. W. Wong. 2007. Construction of an infectious rhesus rhadinovirus bacterial artificial chromosome for the analysis of Kaposi's sarcoma-associated herpesvirus-related disease development. J. Virol. 81:2957-2969.
9. Gunther, T., and A. Grundhoff. 2010. The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes. PLoS Pathog. 6:e1000935.
10. Han, Z., and S. Swaminathan. 2006. Kaposi's sarcoma-associated herpesvi-rus lytic gene ORF57 is essential for infectious virion production. J. Virol. 80:5251-5260.
11. Kato-Noah, T., et al. 2007. Overexpression of the Kaposi's sarcoma-associated herpesvirus transactivator K-Rta can complement a K-bZIP deletion BACmid and yields an enhanced growth phenotype. J. Virol. 81:13519-13532.
12. Krishnan, H. H., N. Sharma-Walia, L. Zeng, S. J. Gao, and B. Chandran. 2005. Envelope glycoprotein gB of Kaposi's sarcoma-associated herpesvirus is essential for egress from infected cells. J. Virol. 79:10952-10967.
13. Lei, X., et al. 2010. Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA. Nat. Cell Biol. 12:193-199.
14. Li, Q., F. Zhou, F. Ye, and S. J. Gao. 2008. Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional program. Virology 379:234-244.
15. Lu, F., W. Stedman, M. Yousef, R. Renne, and P. M. Lieberman. 2010. Epigenetic regulation of Kaposi's sarcoma-associated herpesvirus latency by virus-encoded microRNAs that target Rta and the cellular Rbl2-DNMT pathway. J. Virol. 84:2697-2706.
16. Luna, R. E., et al. 2004. Kaposi's sarcoma-associated herpesvirus glycoprotein K8.1 is dispensable for virus entry. J. Virol. 78:6389-6398.
17. Majerciak, V., N. Pripuzova, J. P. McCoy, S. J. Gao, and Z. M. Zheng. 2007. Targeted disruption of Kaposi's sarcoma-associated herpesvirus ORF57 in the viral genome is detrimental for the expression of ORF59, K8alpha, and K8.1 and the production of infectious virus. J. Virol. 81:1062-1071.
18. Nagel, C. H., et al. 2008. Nuclear egress and envelopment of herpes simplex virus capsids analyzed with dual-color fluorescence HSV1(17+). J. Virol. 82:3109-3124.
19. Russo, J. J., et al. 1996. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc. Natl. Acad. Sci. U. S. A. 93:14862-14867.
20. Sathish, N., and Y. Yuan. 2010. Functional characterization of Kaposi's sarcoma-associated herpesvirus small capsid protein by bacterial artificial chromosome-based mutagenesis. Virology 407:306-318.
21. Soulier, J., et al. 1995. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 86:1276-1280.
22. Xu, Y., et al. 2005. A Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50 deletion mutant is defective for reactivation of latent virus and DNA replication. J. Virol. 79:3479-3487.
23. Xu, Y., A. Rodriguez-Huete, and G. S. Pari. 2006. Evaluation of the lytic origins of replication of Kaposi's sarcoma-associated virus/human herpesvirus 8 in the context of the viral genome. J. Virol. 80:9905-9909.
24. Ye, F. C., et al. 2008. Kaposi's sarcoma-associated herpesvirus latent gene vFLIP inhibits viral lytic replication through NF-kappaB-mediated suppression of the AP-1 pathway: a novel mechanism of virus control of latency. J. Virol. 82:4235-4249.
25. Ye, F. C., et al. 2004. Disruption of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistence. J. Virol. 78: 11121-11129.
26. Yoshii, H., P. Somboonthum, M. Takahashi, K. Yamanishi, and Y. Mori. 2007. Cloning of full length genome of varicella-zoster virus vaccine strain into a bacterial artificial chromosome and reconstitution of infectious virus. Vaccine 25:5006-5012.
27. Zhou, F. C., et al. 2002. Efficient infection by a recombinant Kaposi's sarcoma-associated herpesvirus cloned in a bacterial artificial chromosome: application for genetic analysis. J. Virol. 76:6185-6196.
28. Zhu, F. X., X. Li, F. Zhou, S. J. Gao, and Y. Yuan. 2006. Functional characterization of Kaposi's sarcoma-associated herpesvirus ORF45 by bacterial artificial chromosome-based mutagenesis. J. Virol. 80:12187-12196.