Raf/MEK/ERK signalling triggers reactivation of Kaposi's sarcoma-associated herpesvirus latency

Journal of General Virology

Volumn 87, Issue 5, 2006, Pages 1139-1144

  Ford, Patrick W ^a   Bryan, Benjamin A ^a   Dyson, Ossie F ^a   Weidner, Douglas A ^a   Chintalgattu, Vishnu ^a   Akula, Shaw M ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; BETA ACTIN; GLYCOPROTEIN B; LATENCY ASSOCIATED NUCLEAR ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE; SMALL INTERFERING RNA;

ANGIOFOLLICULAR LYMPH NODE HYPERPLASIA; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; IN VITRO STUDY; IN VIVO STUDY; KAPOSI SARCOMA; PATHOGENESIS; PRIMARY EFFUSION LYMPHOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VIRUS LATENCY; VIRUS REACTIVATION;

CELL LINE, TUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HERPESVIRUS 8, HUMAN; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; PHORBOL ESTERS; PROTO-ONCOGENE PROTEINS B-RAF; SIGNAL TRANSDUCTION; VIRUS ACTIVATION;

HUMAN HERPESVIRUS 8;

EID: 33646148957     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.81628-0     Document Type: Article

References (33)

1. Akula, S. M., Pramod, N. P., Wang, F.-Z. & Chandran, B. (2001). Human herpesvirus 8 envelope-associated glycoprotein B interacts with heparan sulfate-like moieties. Virology 284, 235-249.
2. Akula, S. M., Pramod, N. P., Wang, F.-Z. & Chandran, B. (2002). Integrin α3β1 (CD 49c/29) is a cellular receptor for Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) entry into the target cells. Cell 108, 407-419.
3. Akula, S. M., Ford, P. W., Whitman, A. G., Hamden, K. E., Shelton, J. G. & McCubrey, J. A. (2004). Raf promotes human herpesvirus-8 (HHV-8 /KSHV) infection. Oncogene 23, 5227-5241.
4. Akula, S. M., Ford, P. W., Whitman, A. G., Hamden, K. E., Bryan, B. A., Cook, P. P. & McCubrey, J. A. (2005). B-Raf-dependent expression of vascular endothelial growth factor-A in Kaposi sarcoma-associated herpesvirus-infected human B cells. Blood 105, 4516-4522.
5. An, F.-Q., Compitello, N., Horwitz, E., Sramkoski, M., Knudsen, E. S. & Renne, R. (2005). The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus modulates cellular gene expression and protects lymphoid cells from p16 INK4A-induced cell cycle arrest. J Biol Chem 280, 3862-3874.
6. Bryan, B. A., Dyson, O. F. & Akula, S. M. (2006). Identifying cellular genes crucial for the reactivation of Kaposi's sarcoma-associated herpesvirus latency. J Gen Virol 87, 519-529.
7. Chang, Y., Cesarman, E., Pessin, M. S., Lee, F., Culpepper, J., Knowles, D. M. & Moore, P. S. (1994). Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266, 1865-1869.
8. Cook, S. D., Paveloff, M. J., Doucet, J. J., Cottingham, A. J., Sedarati, F. & Hill, J. M. (1991). Ocular herpes simplex virus reactivation in mice latently infected with latency-associated transcript mutants. Invest Ophthalmol Vis Sci 32, 1558-1561.
9. Deutsch, E., Cohen, A., Kazimirsky, G., Dovrat, S., Rubinfeld, H., Brodie, C. & Sarid, R. (2004). Role of protein kinase C δ in reactivation of Kaposi's sarcoma-associated herpesvirus. J Virol 78, 10187-10192.
10. Ensoli, B., Sgadari, C., Barillari, G., Sirianni, M. C., Stürzl, M. & Monini, P. (2001). Biology of Kaposi's sarcoma. Eur J Cancer 37, 1251-1269.
11. Faris, M., Ensoli, B., Kokot, N. & Nel, A. E. (1998). Inflammatory cytokines induce the expression of basic fibroblast growth factor (bFGF) isoforms required for the growth of Kaposi's sarcoma and endothelial cells through the activation of AP-1 response elements in the bFGF promoter. AIDS 12, 19-27.
12. ERK signal transduction pathway during initial virus infection of quiescent primary B cells and disruption of Epstein-Barr virus latency by phorbol esters. J Virol 73, 8913-8916.
13. Friborg, J., Jr, Kong, W.-P., Hottiger, M. O. & Nabel, G. J. (1999). p53 inhibition by the LANA protein of KSHV protects against cell death. Nature 402, 889-894.
14. Fujimuro, M., Liu, J., Zhu, J., Yokosawa, H. & Hayward, S. D. (2005). Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen. J Virol 79, 10429-10441.
15. Gao, X., Ikuta, K., Tajima, M. & Sairenji, T. (2001). 12-O-Tetradecanoylphorbol-13-acetate induces Epstein-Barr virus reactivation via NF-κB and AP-1 as regulated by protein kinase C and mitogen-activated protein kinase. Virology 286, 91-99.
16. Giri, R. K., Selvaraj, S. K. & Kalra, V. K. (2003). Amyloid peptide-induced cytokine and chemokine expression in THP-1 monocytes is blocked by small inhibitory RNA duplexes for early growth response-1 messenger RNA. J Immunol 170, 5281-5294.
17. Hamden, K. E., Ford, P. W., Whitman, A. G., Dyson, O. F., Cheng, S.-Y., McCubrey, J. A. & Akula, S. M. (2004). Raf-induced vascular endothelial growth factor augments Kaposi's sarcoma-associated herpesvirus infection. J Virol 78, 13381-13390.
18. Jang, B.-C., Jung, T.-Y., Paik, J.-H., Kwon, Y.-K., Shin, S.-W., Kim, S.-P., Ha, J.-S., Suh, M.-H. & Suh, S.-I. (2005). Tetradecanoyl phorbol acetate induces expression of Toll-like receptor 2 in U937 cells: involvement of PKC, ERK, and NF-κB. Biochem Biophys Res Commun 328, 70-77.
19. Jenner, R. G., Albà, M. M., Boshoff, C. & Kellam, P. (2001). Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays. J Virol 75, 891-902.
20. Jordan, M. C., Jordan, G. W., Stevens, J. G. & Miller, G. (1984). Latent herpesviruses of humans. Ann Intern Med 100, 866-880.
21. Karasarides, M., Chiloeches, A., Hayward, R. & 9 other authors (2004). B-RAF is a therapeutic target in melanoma. Oncogene 23, 6292-6298.
22. Lan, K., Kuppers, D. A., Verma, S. C. & Robertson, E. S. (2004). Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency. J Virol 78, 6585-6594.
23. Man, K., Ng, K. T., Lee, T. K., Lo, C. M., Sun, C. K., Li, X. L., Zhao, Y., Ho, J. W. & Fan, S. T. (2005). FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers. Am J Transplant 5, 40-49.
24. Marquardt, B., Frith, D. & Stabel, S. (1994). Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK: reconstitution of the signalling pathway in vitro. Oncogene 9, 3213-3218.
25. 2+-dependent protein kinase C, Raf/ MEK/ERK and IKK /IκB/NF-κB signal cascades. Biochem Pharmacol 69, 433-449.
26. Nakayama, K., Ota, Y., Okugawa, S., Ise, N., Kitazawa, T., Tsukada, K., Kawada, M., Yanagimoto, S. & Kimura, S. (2003). Raf1 plays a pivotal role in lipopolysaccharide-induced activation of dendritic cells. Biochem Biophys Res Commun 308, 353-360.
27. O'Neill, E. & Kolch, W. (2004). Conferring specificity on the ubiquitous Raf/MEK signalling pathway. Br J Cancer 90, 283-288.
28. Radkov, S. A., Kellam, P. & Boshoff, C. (2000). The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells. Nat Med 6, 1121-1127.
29. Renne, R., Zhong, W., Herndier, B., McGrath, M., Abbey, N., Kedes, D. & Ganem, D. (1996). Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat Med 2, 342-346.
30. Satoh, T., Hoshikawa, Y., Satoh, Y., Kurata, T. & Sairenji, T. (1999). The interaction of mitogen-activated protein kinases to Epstein-Barr virus activation in Akata cells. Virus Genes 18, 57-64.
31. Vieira, J., O'Hearn, P., Kimball, L., Chandran, B. & Corey, L. (2001). Activation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) lytic replication by human cytomegalovirus. J Virol 75, 1378-1386.
32. Yang, X., Chen, Y. & Gabuzda, D. (1999). ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-κB. J Biol Chem 274, 27981-27988.
33. Yang, T.-Y., Chen, S.-C., Leach, M. W. & 8 other authors (2000). Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma. J Exp Med 191, 445-454.