SC2: A novel process for manufacturing multipurpose high-density chemical microarrays

QSAR and Combinatorial Science

Volumn 25, Issue 11, 2006, Pages 1069-1080

  Dikmans, Antonius ^a   Beutling, Ulrike ^a   Schmeisser, Edelgard ^a   Thiele, Sabine ^a   Frank, Ronald ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Cellulose conjugates; Chemical microarrays; Diketopiperazine library; Peptide library; Small molecules

Indexed keywords

CALMODULIN; CELLULOSE; MICROARRAYS; MOLECULES; MONOCLONAL ANTIBODIES; PROBES; SYNTHESIS (CHEMICAL);

CELLULOSE CONJUGATES; CHEMICAL ASSEMBLY; CHEMICAL MICROARRAYS; DIKETOPIPERAZINE LIBRARY; DIKETOPIPERAZINES; NOVEL PROCESS; PEPTIDE LIBRARY; PROBE MOLECULES; SMALL MOLECULES; SYNTHETIC PROBES;

PEPTIDES;

CALMODULIN; CELLULOSE; FLUORESCENT DYE; GLASS; MONOCLONAL ANTIBODY; PEPTIDE DERIVATIVE; PIPERAZINEDIONE;

ARTICLE; ELECTRONICS; LIBRARY; MEMBRANE; MICROARRAY ANALYSIS; PRIORITY JOURNAL; SOLUBILIZATION; SYNTHESIS;

EID: 33751516069     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200640130     Document Type: Article

References (18)

1. R. Frank, W. Heikens, G. Heisterberg-Moutsis, H. Blöcker, Nucleic Acids Res. 1983, 11, 4365-4377.
2. R. Frank, R. Döring, Tetrahedron 1988, 44, 6031.
3. R. Frank, Tetrahedron 1992, 48, 9217.
4. F. Dittrich, W. Tegge, R. Frank, Bioorg. Med. Chem. Lett. 1998, 8, 2351.
5. A. J. Dikmans, M. Morr, N. Zander, F. Adler, G. Türk, R. Frank, Mol. Divers. 2004, 8, 197-207.
6. J. Niggemann, R. Frank, K. Michaelis, N. Zander, G. Höfle, J. Chem. Soc. Perkins Trans 2002, 1, 2490-2503.
7. R. Frank, J. Immunol. Methods 2002, 267, 13-26.
8. R. Frank, J. Schneider-Mergener, SPOT-Synthesis - Scope of Applications, J. Koch, M. Mahler (Ed.), Peptide Arrays on Membrane Supports - Synthesis and Applications, Springer Lab Manual, Springer-Verlag, Berlin 2002, 1-24.
9. D. Scharn, H. Wenschuh, U. Reinecke, J. Schneider-Mergener, L. Germeroth, J. Comb. Chem. 2000, 4, 361-369.
10. U. Beutling, A. Dikmans, V. Gupte, A. Swistowski, R. Frank, Process for the manufacturing of chemical microarrays, DE 10 2004 023 906.1 Patent pending 2004.
11. R. Frank, H. Overwin, SPOT-Synthesis: Epitope Analysis with Arrays of Synthetic Peptides Prepared on Cellulose Membranes, G. E. Morris (Ed.), Methods in Molecular Biology Vol. 66, Epitope Mapping Protocols, The Humana Press Inc., Totowa 1996, 149-169.
12. 2-Type Manufacturing of High Density Multi-Purpose Chemical Microarrays, M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.), Peptides 2004, Proc. 28 EuropPeptide, Kenes International, Geneva 2005, 405-406.
13. R. Frank, S. Hoffmann, H. Overwin, C. Behn, H. Gausepohl, Easy Preparation of Synthetic Peptide Repertoires for Immunological Studies Utilizing SPOT Synthesis, C. H. Schneider (Ed.), Peptides in Immunology, John Wiley & Sons, Ltd., Chichester, 1996, 197-204.
14. d of mAb 1D3 was determined according to: B. Friguet, A. F. Chaffotte, L. Djavadi-Ohaniance, M. E. Goldberg, J. Immunol. Methods 1985, 77, 305-319.
15. H. Hidaka, T. Yamaki, M. Naka, T. Tanaka, H. Hayashi, R. Kobayashi, Mol. Pharmacol. 1979, 17, 66-72.
16. M. Osawa, M. B. Swindells, J. Tanikawa, T. Tanaka, T. Mase, T. Furuja, M. Ikura, J. Mol. Biol. 1998, 276, 165-176.
17. U. Beutling, A. Dikmans, S. Thiele, R. Frank, A Novel Process for Manufacturing High Density Multipurpose Chemical Microarrays, M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.), Peptides 2004, Kenes International, Geneva 2005, 152-153.
18. E. Harlow, D. Lane (Eds.), Antibodies - A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor 1988.