Human herpesvirus 6 activates lytic cycle replication of Kaposi's sarcoma-associated herpesvirus

American Journal of Pathology

Volumn 166, Issue 1, 2005, Pages 173-183

  Lu, Chun ^a   Zeng, Yi ^a   Huang, Zan ^b   Huang, Li ^a   Qian, Chao ^a   Tang, Guixia ^a   Qin, Di ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; VIRUS PROTEIN;

ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; HETEROKARYON; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 6; HUMAN HERPESVIRUS 8; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; VIRION; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN;

EID: 11144242118     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)62242-0     Document Type: Article

References (66)

1. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS: Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994, 266:1865-1869
2. Moore PS, Gao SJ, Dominguez G, Cesarman E, Lungu O, Knowles DM, Garber R, Pellett PE, McGeoch DJ, Chang Y: Primary characterization of a herpesvirus agent associated with Kaposi's sarcoma. J Virol 1996, 70:549-558
3. Katano H, Sata T: Human herpesvirus 8: virology, epidemiology and related diseases. Jpn J Infect Dis 2000, 53:137-155
4. Schulz TF: Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). J Gen Virol 1998, 79:1573-1591
5. Moore PS, Chang Y: Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infection. N Engl J Med 1995, 332:1181-1185
6. Bashoff C, Whitby D, Hatziioannou T, Fisher C, van der Walt J, Hatzakis A, Weiss R, Schulz T: Kaposi's-sarcoma-associated herpesvirus in HIV-negative Kaposi's sarcoma. Lancet 1995, 345:1043-1044
7. Ambroziak JA, Blackbourn DJ, Herndier BG, Glogau RG, Gullett JH, McDonald AR, Lennette ET, Levy JA: Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients. Science 1995, 268:582-583
8. Sitas F, Carrara H, Beral V, Newton R, Reeves G, Bull, Jentsch U, Pacella-Norman R, Bourboulia D, Whitby D, Boshoff C, Weiss R: Antibodies against human herpesvirus 8 in black South African patients with cancer. N Engl J Med 1999, 340:1863-1871
9. Kedes DH, Operskalski E, Busch M, Kohn R, Flood J, Ganem D: The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission. Nat Med 1996, 2:918-924
10. Gao SJ, Kingsley L, Hoover DR, Spira TJ, Rinaldo CR, Saah A, Phair J, Detels R, Parry P, Chang Y, Moore PS: Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma. N Engl J Med 1996, 335:233-241
11. Lennette ET, Blackbourn DJ, Levy JA: Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. Lancet 1996, 348:858-861
12. Staskus KA, Zhong WD, Gebhard K, Herndier B, Wang H, Renne R, Beneke J, Pudney J, Anderson DJ, Ganem D, Hasse AT: Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells. J Virol 1997, 71:715-719
13. Renne R, Zhong WD, Herndier B, McGrath M, Abbey N, Kedes D, Ganem D: Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat Med 1996, 2:342-346
14. Renne R, Lagunoff M, Zhong W, Ganem D: The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions. J Virol 1996, 70:8151-8154
15. Decker LL, Shankar P, Khan G, Freeman RB, Dezube BJ, Lieberman J, Thorley-Lawson DA: The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients. J Exp Med 1996, 184:283-288
16. Sturzl M, Blasig C, Schreier A, Neipel F, Hohenadl C, Cornali E, Ascherl G, Esser S, Brockmeyer NH, Ekman M, Kaaya EE, Tschachler E, Biberfeld P: Expression of HHV-8 latency-associated T0.7 RNA in spindle cells and endothelial cells of AIDS-associated, classical and African Kaposi's sarcoma. Int J Cancer 1997, 72:68-71
17. Friedman-Kien AE, Laubenstein LJ, Rubinstein P, Buimovici-Klein E, Marmor M, Stahl R, Spigland I, Kim KS, Zolla-Pazner S: Disseminated Kaposi's sarcoma in homosexual men. Ann Intern Med 1982, 96:693-700
18. Buchbinder A, Friedman-Kien AE: Clinical aspects of Kaposi's sarcoma. Curr Opin Oncol 1992, 4:867-874
19. Strathdee SA, Veugelers PJ, Moore PS: The epidemiology of HIV-associated Kaposi's sarcoma: the unraveling mystery. AIDS 1996, 10(Suppl A):S51-S57
20. Delli BP, Donti E, Knowles DM, Friedman-Kien A, Luciw PA, Dina D, Dalla-Favera R, Basilico C: Presence of chromosomal abnormalities and lack of AIDS retrovirus DNA sequences in AIDS-associated Kaposi's sarcoma. Cancer Res 1986, 46:6333-6338
21. Mercader M, Taddeo B, Panella JR, Chandran B, Nickoloff BJ, Foreman KE: Induction of HHV-8 lytic cycle replication by inflammatory cytokines produced by HIV-1-infected T cells. Am J Pathol 2000, 156:1961-1971
22. Ariyoshi K, Schim van der Loeff M, Cook P, Whitby D, Corrah T, Jaffar S, Cham F, Sabally S, O'Donovan D, Weiss RA, Schulz TF, Whittle H: Kaposi's sarcoma in the Gambia, West Africa is less frequent in human immunodeficiency virus type 2 than in human immunodeficiency virus type 1 infection despite a high prevalence of human herpesvirus 8. J Hum Virol 1998, 1:193-199
23. Giraldo G, Beth E, Huang ES: Kaposi's sarcoma and its relationship to cytomegalovirus (CMNV). III. CMV DNA and CMV early antigens in Kaposi's sarcoma. Int J Cancer 1980, 26:23-29
24. Vieira J, O'hearn P, Kimball L, Chandran B, Corey L: Activation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) lytic replication by human cytomegalovirus. J Virol 2001, 75:1378-1386
25. Kempf W, Adams V: Viruses in the pathogenesis of Kaposi's sarcoma - a review. Biochem Mol Med 1996, 58:1-12
26. Adams V, Kempf W, Hassam S, Briner J, Schmid M, Moos R, Pfaltz M: Detection of several types of human papilloma viruses in AIDS-associated Kaposi's sarcoma. J Med Virol 1995, 46:189-193
27. Monini P, Rotola A, de Lellis L, Corallini A, Secchiero P, Albini A, Benelli R, Parravicini C, Barbanti Brodano G, Cassai E: Latent BK virus infection and Kaposi's sarcoma pathogenesis. Int J Cancer 1996, 66:717-722
28. Secchiero P, Carrigan DR, Asano Y, Benedetti L, Crowley RW, Komaroff AL, Gallo R, Lusso P: Detection of human herpesvirus 6 in plasma of children with primary infection and immunosuppressed patients by polymerase chain reaction. J Infect Dis 1995, 171:273-280
29. Bovenzi P, Mirandola P, Secchiero P, Strumia R, Cassai E, Di Luca D: Human herpesvirus 6 (variant A) in Kaposi's sarcoma. Lancet 1993, 341:1288-1289
30. Di Luca D, Dolcetti R, Mirandola P, De Re V, Secchiero P, Carbone A, Boiocchi M, Cassai E: Human herpesvirus 6: a survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders. J Infect Dis 1994, 170:211-215
31. Marchette NJ, Melish ME, Hicks R, Kihara S, Sam E, Ching D: Epstein-Barr virus and other herpesvirus infections in Kawasaki syndrome. J Infect Dis 1990, 161:680-684
32. Kempf W, Adams V, Hassam S, Schmid M, Moos R, Briner J, Pfaltz M: Detection of human herpesvirus type 6, human herpesvirus type 7, cytomegalovirus and human papillomavirus in cutaneous AIDS-associated Kaposi's sarcoma. Verh Dtsch Ges Pathol 1994, 78:260-264
33. Kempf W, Adams V, Pfaltz M, Briner J, Schmid M, Moos R, Hassam S: Human herpesvirus type 6 and cytomegalovirus in AIDS-associated Kaposi's sarcoma: no evidence for an etiological association. Hum Pathol 1995, 26:914-919
34. Flamand L, Stefanescu I, Ablashi DV, Menezes J: Activation of the Epstein-Barr virus replicative cycle by human herpesvirus 6. J Virol 1993, 67:6768-6777
35. Vieira J, O'hearn P, Kimball L, Chandran B, Corey L: Activation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) lytic replication by human cytomegalovirus. J Virol 2001, 75:1378-1386
36. Tedder RS, Briggs M, Cameron CH, Honess R, Robertson D, Whittle H: A novel lymphotropic herpesvirus. Lancet 1987, 2:390-392
37. Cesarman E, Moore PS, Rao PH, Inghirami G, Knowles DM, Chang Y: In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences. Blood 1995, 86:2708-2714
38. Downing RG, Sewankambo N, Serwadda D, Honess R, Crawford D, Jarrett R, Griffin BE: Isolation of human lymphotropic herpesviruses from Uganda. Lancet 1987, 2:390
39. Schirmer EC, Wyatt LS, Yamanishi K, Rodriguez WJ, Frenkel N: Differentiation between two distinct classes of viruses now classified as human herpesvirus 6. Proc Natl Acad Sci USA 1991, 88:5922-5926
40. Herrin DL, Schmidt GW: Rapid, reversible staining of Northern blots prior to hybridization. Biotechniques 1988, 6:196-200
41. Lu C, Gordon GM, Chandran B, Nickoloff BJ, Foreman KE: Human herpesvirus 8 reactivation and human immunodeficiency virus type 1 gp120. Arch Pathol Lab Med 2002, 126:941-946
42. Foreman KE, Friborg J, Kong W, Woffendin C, Polverini PJ, Nickoloff BJ, Nabel GJ: Propagation of a human herpesvirus from AIDS-associated Kaposi's sarcoma. N Engl J Med 1997, 336:163-171
43. Lu F, Zhou J, Wiedmer A, Madden K, Yuan Y, Lieberman PM: Chromatin remodeling of the Kaposi's sarcoma-associated herpesvirus ORF50 promoter correlates with reactivation from latency. J Virol 2003, 77:11425-11435
44. Huang LM, Chao MF, Chen MY, Shih HM, Chiang YP, Chuang CY, Lee CY: Reciprocal regulatory interaction between human herpesvirus 8 and human immunodeficiency virus type 1. J Biol Chem 2001, 276:13427-13432
45. Wunschmann S, Stapleton JT: Fluorescence-based quantitative methods for detecting human immunodeficiency virus type 1-induced syncytia. J Clin Microbiol 2000, 38:3055-3060
46. Foreman KE, Alkan S, Krueger AE, Panella JR, Swinnen LJ, Nickoloff BJ: Geographically distinct HHV-8 DNA sequences in Saudi Arabian iatrogenic Kaposi's sarcoma lesions. Am J Pathol 1998, 153:1001-1004
47. Knipping E, Krammer PH, Onel KB, Lehman TJ, Mysler E, Elkon KB: Levels of soluble Fas/APO-1/CD95 in systemic lupus erythematosus and juvenile rheumatoid arthritis. Arthritis Rheum 1995, 38:1735-1737
48. Chandran B, Bloomer C, Chan SR, Zhu L, Goldstein E, Horvat R: Human herpesvirus-8 ORF K8.1 gene encodes immunogenic glycoproteins generated by spliced transcripts. Virology 1998, 249:140-149
49. Chan SR, Bloomer C, Chandran B: Identification and characterization of human herpesvirus-8 lytic cycle-associated ORF59 protein and the encoding cDNA by monoclonal antibody. Virology 1998, 240:118-126
50. Zhu L, Puri V, Chandran B: Characterization of human herpesvirus-8 K8.1 A/B glycoproteins by monoclonal antibodies. Virology 1999, 262:237-249
51. Santoro F, Kennedy PE, Locatelli G, Malnati MS, Berger EA, Lusso P: CD46 is a cellular receptor for human herpesvirus 6. Cell 1999, 99:817-827
52. Sun R, Lin SF, Gradoville L, Yuan Y, Zhu F, Miller G: A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus. Proc Natl Acad Sci USA 1998, 95:10866-10871
53. Lukac DM, Renne R, Kirshner JR, Ganem D: Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF50 transactivator, a homolog of the EBV R protein. Virology 1998, 252:304-312
54. Zoeteweij JP, Eyes ST, Orenstein JM, Kawamura T, Wu L, Chandran B, Forghani B, Blauvelt A: Identification and rapid quantification of early and late lytic human herpesvirus 8 infection in single cells by flow cytometric analysis: characterization of antiherpesvirus agents. J Virol 1999, 73:5894-5902
55. Blasig C, Zietz C, Haar B, Neipel F, Esser S, Brockmeyer NH, Tschachler E, Colombini S, Ensoli B, Sturzl M: Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8. J Virol 1997, 71:7963-7968
56. Gradoville L, Gerlach J, Grogan E, Shedd D, Nikiforow S, Metroka C, Miller G: Kaposi's sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire viral lytic cycle in the HH-B2 primary effusion lymphoma cell line. J Virol 2000, 74:6207-6212
57. Parravicini C, Chandran B, Corbellino M, Berti E, Paulli M, Moore PS, Chang Y: Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus infected diseases: Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease. Am J Pathol 2000, 156:743-749
58. Varthakavi V, Smith RM, Deng H, Sun R, Spearman P: Human immunodeficiency virus type-1 activates lytic cycle replication of Kaposi's sarcoma-associated herpesvirus through induction of KSHV Rta. Virology 2002, 297:270-280
59. Ensoli B, Barillari G, Buonaguro L, Gallo RC: Molecular mechanisms in the pathogenesis of AIDS-associated Kaposi's sarcoma. Adv Exp Med Biol 1991, 303:27-38
60. Fiorelli V, Gendelman R, Samaniego F, Markham PD, Ensoli B: Cytokines from activated T cells induce normal endothelial cells to acquire the phenotypic and functional features of AIDS-Kaposi's sarcoma spindle cells. J Clin Invest 1995, 95:1723-1734
61. Ensoli B, Nakamura S, Salahuddin SZ, Biberfeld P, Larsson L, Beaver B, Wong-Staal F, Gallo RC: AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects. Science 1989, 243:223-226
62. Ensoli B, Barillari G, Gallo RC: Cytokines and growth factors in the pathogenesis of AIDS-associated Kaposi's sarcoma. Immunol Rev 1992, 127:147-155
63. Ensoli B, Cafaro A: HIV-1 and Kaposi's sarcoma. Eur J Cancer Prev 1996, 5:410-412
64. Harrington W, Sieczkowski L, Sosa C, Chan-a-Sue S, Cai JP, Cabrao L, Wood C: Activation of HHV-8 by HIV-1 tat. Lancet 1997, 349:774-775
65. Zhou Y, Chang CK, Qian G, Chandran B, Wood C: trans-Activation of the HIV promoter by a cDNA and its genomic clones of human herpesvirus 6. Virology 1994, 199:311-322
66. Sieczkowski L, Chandran B, Wood C: The human immunodeficiency virus tat gene enhances replication of human herpesvirus-6. Virology 1995, 211:544-553