메뉴 건너뛰기




Volumn 88, Issue 22, 2014, Pages 13161-13172

Activation of NF-κB by the Kaposi's sarcoma-associated herpesvirus K15 protein involves recruitment of the NF-κB-inducing kinase, IκB kinases, and phosphorylation of p65

Author keywords

[No Author keywords available]

Indexed keywords

DNA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; K15 PROTEIN; NUCLEAR FACTOR KAPPA B INDUCING KINASE; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE; SERINE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; VIRUS PROTEIN; CHUK PROTEIN, HUMAN; K15 PROTEIN, HUMAN HERPESVIRUS 8; NF-KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE; RELA PROTEIN, HUMAN; VIRAL PROTEIN;

EID: 84908374503     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01766-14     Document Type: Article
Times cited : (27)

References (77)
  • 1
    • 0028588064 scopus 로고
    • Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
    • Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS. 1994. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266:1865-1869. http://dx.doi.org/10.1126/science.7997879.
    • (1994) Science , vol.266 , pp. 1865-1869
    • Chang, Y.1    Cesarman, E.2    Pessin, M.S.3    Lee, F.4    Culpepper, J.5    Knowles, D.M.6    Moore, P.S.7
  • 2
    • 0029005449 scopus 로고
    • Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and withoutHIVinfection
    • Moore PS, Chang Y. 1995. Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and withoutHIVinfection. N. Engl. J. Med. 332:1181-1185. http://dx.doi.org/10.1056/NEJM199505043321801.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1181-1185
    • Moore, P.S.1    Chang, Y.2
  • 3
    • 0034971887 scopus 로고    scopus 로고
    • KSHV/HHV8-associated lymphoproliferations in the AIDS setting
    • Schulz TF. 2001. KSHV/HHV8-associated lymphoproliferations in the AIDS setting. Eur. J. Cancer 37:1217-1226. http://dx.doi.org/10.1016/S0959-8049(01)00115-0.
    • (2001) Eur. J. Cancer , vol.37 , pp. 1217-1226
    • Schulz, T.F.1
  • 4
    • 0029069445 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas
    • Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM. 1995. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N. Engl. J. Med. 332:1186-1191. http://dx.doi.org/10.1056/NEJM199505043321802.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1186-1191
    • Cesarman, E.1    Chang, Y.2    Moore, P.S.3    Said, J.W.4    Knowles, D.M.5
  • 8
    • 0034630323 scopus 로고    scopus 로고
    • Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma, and multicentric Castleman's disease
    • Katano H, Sato Y, Kurata T, Mori S, Sata T. 2000. Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma, and multicentric Castleman's disease. Virology 269:335-344. http://dx.doi.org/10.1006/viro.2000.0196.
    • (2000) Virology , vol.269 , pp. 335-344
    • Katano, H.1    Sato, Y.2    Kurata, T.3    Mori, S.4    Sata, T.5
  • 9
    • 0033901248 scopus 로고    scopus 로고
    • Differential viral protein expression in Kaposi's sarcomaassociated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease
    • Parravicini C, Chandran B, Corbellino M, Berti E, Paulli M, Moore PS, Chang Y. 2000. Differential viral protein expression in Kaposi's sarcomaassociated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Am. J. Pathol. 156: 743-749. http://dx.doi.org/10.1016/S0002-9440(10)64940-1.
    • (2000) Am. J. Pathol. , vol.156 , pp. 743-749
    • Parravicini, C.1    Chandran, B.2    Corbellino, M.3    Berti, E.4    Paulli, M.5    Moore, P.S.6    Chang, Y.7
  • 10
    • 0030834122 scopus 로고    scopus 로고
    • The 222-to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen
    • Rainbow L, Platt GM, Simpson GR, Sarid R, Gao SJ, Stoiber H, Herrington CS, Moore PS, Schulz TF. 1997. The 222-to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen. J. Virol. 71:5915-5921.
    • (1997) J. Virol. , vol.71 , pp. 5915-5921
    • Rainbow, L.1    Platt, G.M.2    Simpson, G.R.3    Sarid, R.4    Gao, S.J.5    Stoiber, H.6    Herrington, C.S.7    Moore, P.S.8    Schulz, T.F.9
  • 12
    • 0036118279 scopus 로고    scopus 로고
    • Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus
    • Chiou CJ, Poole LJ, Kim PS, Ciufo DM, Cannon JS, ap Rhys CM, Alcendor DJ, Zong JC, Ambinder RF, Hayward GS. 2002. Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus. J. Virol. 76:3421-3439. http://dx.doi.org/10.1128/JVI.76.7.3421-3439.2002.
    • (2002) J. Virol. , vol.76 , pp. 3421-3439
    • Chiou, C.J.1    Poole, L.J.2    Kim, P.S.3    Ciufo, D.M.4    Cannon, J.S.5    ap Rhys, C.M.6    Alcendor, D.J.7    Zong, J.C.8    Ambinder, R.F.9    Hayward, G.S.10
  • 13
    • 0033989865 scopus 로고    scopus 로고
    • Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome
    • Choi JK, Lee BS, Shim SN, Li M, Jung JU. 2000. Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome. J. Virol. 74:436-446. http://dx.doi.org/10.1128/JVI.74.1.436-446.2000.
    • (2000) J. Virol. , vol.74 , pp. 436-446
    • Choi, J.K.1    Lee, B.S.2    Shim, S.N.3    Li, M.4    Jung, J.U.5
  • 14
    • 0032775720 scopus 로고    scopus 로고
    • Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus
    • Glenn M, Rainbow L, Aurade F, Davison A, Schulz TF. 1999. Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus. J. Virol. 73:6953-6963.
    • (1999) J. Virol. , vol.73 , pp. 6953-6963
    • Glenn, M.1    Rainbow, L.2    Aurade, F.3    Davison, A.4    Schulz, T.F.5
  • 15
    • 0032786533 scopus 로고    scopus 로고
    • Comparison of genetic variability at multiple loci across the genomes of the major subtypes of Kaposi's sarcoma-associated herpesvirus reveals evidence for recombination and for two distinct types of open reading frame K15 alleles at the right-hand end
    • Poole LJ, Zong JC, Ciufo DM, Alcendor DJ, Cannon JS, Ambinder R, Orenstein JM, Reitz MS, Hayward GS. 1999. Comparison of genetic variability at multiple loci across the genomes of the major subtypes of Kaposi's sarcoma-associated herpesvirus reveals evidence for recombination and for two distinct types of open reading frame K15 alleles at the right-hand end. J. Virol. 73:6646-6660.
    • (1999) J. Virol. , vol.73 , pp. 6646-6660
    • Poole, L.J.1    Zong, J.C.2    Ciufo, D.M.3    Alcendor, D.J.4    Cannon, J.S.5    Ambinder, R.6    Orenstein, J.M.7    Reitz, M.S.8    Hayward, G.S.9
  • 17
    • 0041387452 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase and NFkappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein
    • Brinkmann MM, Glenn M, Rainbow L, Kieser A, Henke-Gendo C, Schulz TF. 2003. Activation of mitogen-activated protein kinase and NFkappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein. J. Virol. 77:9346-9358. http://dx.doi.org/10.1128/JVI.77.17.9346-9358.2003.
    • (2003) J. Virol. , vol.77 , pp. 9346-9358
    • Brinkmann, M.M.1    Glenn, M.2    Rainbow, L.3    Kieser, A.4    Henke-Gendo, C.5    Schulz, T.F.6
  • 18
    • 33845736881 scopus 로고    scopus 로고
    • Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus
    • Brinkmann MM, Pietrek M, Dittrich-Breiholz O, Kracht M, Schulz TF. 2007. Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus. J. Virol. 81:42-58. http://dx.doi.org/10.1128/JVI.00648-06.
    • (2007) J. Virol. , vol.81 , pp. 42-58
    • Brinkmann, M.M.1    Pietrek, M.2    Dittrich-Breiholz, O.3    Kracht, M.4    Schulz, T.F.5
  • 19
    • 0028170816 scopus 로고
    • Structure, regulation and function of NF-kappa B
    • Siebenlist U, Franzoso G, Brown K. 1994. Structure, regulation and function of NF-kappa B. Annu. Rev. Cell Biol. 10:405-455. http://dx.doi.org/10.1146/annurev.cb.10.110194.002201.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 405-455
    • Siebenlist, U.1    Franzoso, G.2    Brown, K.3
  • 20
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: new discoveries and insights
    • Baldwin AS, Jr. 1996. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649-683. http://dx.doi.org/10.1146/annurev.immunol.14.1.649.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 21
    • 0033996762 scopus 로고    scopus 로고
    • The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling
    • Karin M, Delhase M. 2000. The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling. Semin. Immunol. 12:85-98. http://dx.doi.org/10.1006/smim.2000.0210.
    • (2000) Semin. Immunol. , vol.12 , pp. 85-98
    • Karin, M.1    Delhase, M.2
  • 22
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-kappaB activation pathways and their role in innate and adaptive immunity
    • Bonizzi G, Karin M. 2004. The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25:280-288. http://dx.doi.org/10.1016/j.it.2004.03.008.
    • (2004) Trends Immunol. , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 23
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS, Ghosh S. 2004. Signaling to NF-kappaB. Genes Dev. 18: 2195-2224. http://dx.doi.org/10.1101/gad.1228704.
    • (2004) Genes Dev. , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 24
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • Karin M, Lin A. 2002. NF-kappaB at the crossroads of life and death. Nat. Immunol. 3:221-227. http://dx.doi.org/10.1038/ni0302-221.
    • (2002) Nat. Immunol. , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 25
    • 0035883151 scopus 로고    scopus 로고
    • NF-kappaB signaling pathways in mammalian and insect innate immunity
    • Silverman N, Maniatis T. 2001. NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15:2321-2342. http://dx.doi.org/10.1101/gad.909001.
    • (2001) Genes Dev. , vol.15 , pp. 2321-2342
    • Silverman, N.1    Maniatis, T.2
  • 26
    • 0036794398 scopus 로고    scopus 로고
    • BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells
    • Claudio E, Brown K, Park S, Wang H, Siebenlist U. 2002. BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Nat. Immunol. 3:958-965. http://dx.doi.org/10.1038/ni842.
    • (2002) Nat. Immunol. , vol.3 , pp. 958-965
    • Claudio, E.1    Brown, K.2    Park, S.3    Wang, H.4    Siebenlist, U.5
  • 28
    • 18644380147 scopus 로고    scopus 로고
    • The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways
    • Dejardin E, Droin NM, Delhase M, Haas E, Cao Y, Makris C, Li ZW, Karin M, Ware CF, Green DR. 2002. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 17:525-535. http://dx.doi.org/10.1016/S1074-7613(02) 00423-5.
    • (2002) Immunity , vol.17 , pp. 525-535
    • Dejardin, E.1    Droin, N.M.2    Delhase, M.3    Haas, E.4    Cao, Y.5    Makris, C.6    Li, Z.W.7    Karin, M.8    Ware, C.F.9    Green, D.R.10
  • 32
    • 0037413709 scopus 로고    scopus 로고
    • RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF
    • Yilmaz ZB, Weih DS, Sivakumar V, Weih F. 2003. RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J. 22:121-130. http://dx.doi.org/10.1093/emboj/cdg004.
    • (2003) EMBO J. , vol.22 , pp. 121-130
    • Yilmaz, Z.B.1    Weih, D.S.2    Sivakumar, V.3    Weih, F.4
  • 33
    • 0035896422 scopus 로고    scopus 로고
    • Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice
    • Yin L, Wu L, Wesche H, Arthur CD, White JM, Goeddel DV, Schreiber RD. 2001. Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. Science 291:2162-2165. http://dx.doi.org/10.1126/science.1058453.
    • (2001) Science , vol.291 , pp. 2162-2165
    • Yin, L.1    Wu, L.2    Wesche, H.3    Arthur, C.D.4    White, J.M.5    Goeddel, D.V.6    Schreiber, R.D.7
  • 34
    • 0032583947 scopus 로고    scopus 로고
    • NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176
    • Ling L, Cao Z, Goeddel DV. 1998. NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176. Proc. Natl. Acad. Sci. U. S. A. 95:3792-3797. http://dx.doi.org/10.1073/pnas.95.7.3792.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 3792-3797
    • Ling, L.1    Cao, Z.2    Goeddel, D.V.3
  • 35
    • 0034745420 scopus 로고    scopus 로고
    • NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
    • Xiao G, Harhaj EW, Sun SC. 2001. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol. Cell 7:401-409. http://dx.doi.org/10.1016/S1097-2765(01)00187-3.
    • (2001) Mol. Cell , vol.7 , pp. 401-409
    • Xiao, G.1    Harhaj, E.W.2    Sun, S.C.3
  • 36
    • 0029058962 scopus 로고
    • Transactivation domain 2 (TA2) of p65 NF-kappa B. Similarity to TA1 and phorbol esterstimulated activity and phosphorylation in intact cells
    • Schmitz ML, dos Santos Silva MA, Baeuerle PA. 1995. Transactivation domain 2 (TA2) of p65 NF-kappa B. Similarity to TA1 and phorbol esterstimulated activity and phosphorylation in intact cells. J. Biol. Chem. 270: 15576-15584.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15576-15584
    • Schmitz, M.L.1    dos Santos Silva, M.A.2    Baeuerle, P.A.3
  • 37
    • 0028960452 scopus 로고
    • Interaction of the COOH-terminal transactivation domain of p65 NFkappa B with TATA-binding protein, transcription factor IIB, and coactivators
    • Schmitz ML, Stelzer G, Altmann H, Meisterernst M, Baeuerle PA. 1995. Interaction of the COOH-terminal transactivation domain of p65 NFkappa B with TATA-binding protein, transcription factor IIB, and coactivators. J. Biol. Chem. 270:7219-7226. http://dx.doi.org/10.1074/jbc.270.13.7219.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7219-7226
    • Schmitz, M.L.1    Stelzer, G.2    Altmann, H.3    Meisterernst, M.4    Baeuerle, P.A.5
  • 38
    • 0032491485 scopus 로고    scopus 로고
    • Activation of nuclear factor-kappaBdependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529
    • Wang D, Baldwin AS, Jr. 1998. Activation of nuclear factor-kappaBdependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529. J. Biol. Chem. 273: 29411-29416. http://dx.doi.org/10.1074/jbc.273.45.29411.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29411-29416
    • Wang, D.1    Baldwin Jr., A.S.2
  • 39
    • 0034693133 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II
    • Wang D, Westerheide SD, Hanson JL, Baldwin AS, Jr. 2000. Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II. J. Biol. Chem. 275:32592-32597. http://dx.doi.org/10.1074/jbc.M001358200.
    • (2000) J. Biol. Chem. , vol.275 , pp. 32592-32597
    • Wang, D.1    Westerheide, S.D.2    Hanson, J.L.3    Baldwin Jr., A.S.4
  • 40
    • 2442429408 scopus 로고    scopus 로고
    • Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import
    • Mattioli I, Sebald A, Bucher C, Charles RP, Nakano H, Doi T, Kracht M, Schmitz ML. 2004. Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import. J. Immunol. 172:6336-6344. http://dx.doi.org/10.4049/jimmunol.172.10.6336.
    • (2004) J. Immunol. , vol.172 , pp. 6336-6344
    • Mattioli, I.1    Sebald, A.2    Bucher, C.3    Charles, R.P.4    Nakano, H.5    Doi, T.6    Kracht, M.7    Schmitz, M.L.8
  • 41
    • 0032589462 scopus 로고    scopus 로고
    • IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain
    • Sakurai H, Chiba H, Miyoshi H, Sugita T, Toriumi W. 1999. IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J. Biol. Chem. 274:30353-30356. http://dx.doi.org/10.1074/jbc.274.43.30353.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30353-30356
    • Sakurai, H.1    Chiba, H.2    Miyoshi, H.3    Sugita, T.4    Toriumi, W.5
  • 42
    • 0037428385 scopus 로고    scopus 로고
    • The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536
    • Jiang X, Takahashi N, Matsui N, Tetsuka T, Okamoto T. 2003. The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536. J. Biol. Chem. 278:919-926. http://dx.doi.org/10.1074/jbc.M208696200.
    • (2003) J. Biol. Chem. , vol.278 , pp. 919-926
    • Jiang, X.1    Takahashi, N.2    Matsui, N.3    Tetsuka, T.4    Okamoto, T.5
  • 43
  • 45
    • 0033596124 scopus 로고    scopus 로고
    • Aberrant rel/nfkb genes and activity in human cancer
    • Rayet B, Gelinas C. 1999. Aberrant rel/nfkb genes and activity in human cancer. Oncogene 18:6938-6947. http://dx.doi.org/10.1038/sj.onc.1203221.
    • (1999) Oncogene , vol.18 , pp. 6938-6947
    • Rayet, B.1    Gelinas, C.2
  • 46
    • 0344441264 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kappaB2 to p52 via an IKKgamma/NEMO-independent signalling pathway
    • Eliopoulos AG, Caamano JH, Flavell J, Reynolds GM, Murray PG, Poyet JL, Young LS. 2003. Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kappaB2 to p52 via an IKKgamma/NEMO-independent signalling pathway. Oncogene 22:7557-7569. http://dx.doi.org/10.1038/sj.onc.1207120.
    • (2003) Oncogene , vol.22 , pp. 7557-7569
    • Eliopoulos, A.G.1    Caamano, J.H.2    Flavell, J.3    Reynolds, G.M.4    Murray, P.G.5    Poyet, J.L.6    Young, L.S.7
  • 47
    • 0035192960 scopus 로고    scopus 로고
    • LMP1 structure and signal transduction
    • Eliopoulos AG, Young LS. 2001. LMP1 structure and signal transduction. Semin. Cancer Biol. 11:435-444. http://dx.doi.org/10.1006/scbi.2001.0410.
    • (2001) Semin. Cancer Biol. , vol.11 , pp. 435-444
    • Eliopoulos, A.G.1    Young, L.S.2
  • 48
    • 0034948735 scopus 로고    scopus 로고
    • Cytokine signaling and Epstein-Barr virus-mediated cell transformation
    • Mosialos G. 2001. Cytokine signaling and Epstein-Barr virus-mediated cell transformation. Cytokine Growth Factor Rev. 12:259-270. http://dx.doi.org/10.1016/S1359-6101(00)00035-6.
    • (2001) Cytokine Growth Factor Rev. , vol.12 , pp. 259-270
    • Mosialos, G.1
  • 49
    • 0035887040 scopus 로고    scopus 로고
    • TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1
    • Schultheiss U, Puschner S, Kremmer E, Mak TW, Engelmann H, Hammerschmidt W, Kieser A. 2001. TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1. EMBO J. 20:5678-5691. http://dx.doi.org/10.1093/emboj/20.20.5678.
    • (2001) EMBO J. , vol.20 , pp. 5678-5691
    • Schultheiss, U.1    Puschner, S.2    Kremmer, E.3    Mak, T.W.4    Engelmann, H.5    Hammerschmidt, W.6    Kieser, A.7
  • 51
    • 84865734196 scopus 로고    scopus 로고
    • The germinal center kinase TNIK is required for canonical NF-kappaB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor
    • e1001376
    • Shkoda A, Town JA, Griese J, Romio M, Sarioglu H, Knofel T, Giehler F, Kieser A. 2012. The germinal center kinase TNIK is required for canonical NF-kappaB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. PLoS Biol. 10:e1001376. http://dx.doi.org/10.1371/journal.pbio.1001376.
    • (2012) PLoS Biol. , vol.10
    • Shkoda, A.1    Town, J.A.2    Griese, J.3    Romio, M.4    Sarioglu, H.5    Knofel, T.6    Giehler, F.7    Kieser, A.8
  • 52
    • 0032898259 scopus 로고    scopus 로고
    • Role of cellular tumor necrosis factor receptor-associated factors in NF-kappaB activation and lymphocyte transformation by herpesvirus Saimiri STP
    • Lee H, Choi JK, Li M, Kaye K, Kieff E, Jung JU. 1999. Role of cellular tumor necrosis factor receptor-associated factors in NF-kappaB activation and lymphocyte transformation by herpesvirus Saimiri STP. J. Virol. 73: 3913-3919.
    • (1999) J. Virol. , vol.73 , pp. 3913-3919
    • Lee, H.1    Choi, J.K.2    Li, M.3    Kaye, K.4    Kieff, E.5    Jung, J.U.6
  • 53
    • 1842640502 scopus 로고    scopus 로고
    • Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation
    • Sorokina EM, Merlo JJ, Jr, Tsygankov AY. 2004. Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation. J. Biol. Chem. 279:13469-13477. http://dx.doi.org/10.1074/jbc.M305250200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 13469-13477
    • Sorokina, E.M.1    Merlo Jr., J.J.2    Tsygankov, A.Y.3
  • 54
    • 33646848934 scopus 로고    scopus 로고
    • NFkappaB signaling is induced by the oncoprotein Tio through direct interaction with TRAF6
    • Heinemann S, Biesinger B, Fleckenstein B, Albrecht JC. 2006. NFkappaB signaling is induced by the oncoprotein Tio through direct interaction with TRAF6. J. Biol. Chem. 281:8565-8572. http://dx.doi.org/10.1074/jbc.M510891200.
    • (2006) J. Biol. Chem. , vol.281 , pp. 8565-8572
    • Heinemann, S.1    Biesinger, B.2    Fleckenstein, B.3    Albrecht, J.C.4
  • 56
    • 21644463312 scopus 로고    scopus 로고
    • Respiratory syncytial virus influences NF-kappaB-dependent gene expression through a novel pathway involving MAP3K14/NIK expression and nuclear complex formation with NF-kappaB2
    • Choudhary S, Boldogh S, Garofalo R, Jamaluddin M, Brasier AR. 2005. Respiratory syncytial virus influences NF-kappaB-dependent gene expression through a novel pathway involving MAP3K14/NIK expression and nuclear complex formation with NF-kappaB2. J. Virol. 79:8948-8959. http://dx.doi.org/10.1128/JVI.79.14.8948-8959.2005.
    • (2005) J. Virol. , vol.79 , pp. 8948-8959
    • Choudhary, S.1    Boldogh, S.2    Garofalo, R.3    Jamaluddin, M.4    Brasier, A.R.5
  • 57
    • 53149137461 scopus 로고    scopus 로고
    • Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kappa B2 complexes via a novel retinoic acid-inducible gene-I{middle dot}NF-kappa B-inducing kinase signaling pathway
    • Liu P, Li K, Garofalo RP, Brasier AR. 2008. Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kappa B2 complexes via a novel retinoic acid-inducible gene-I{middle dot}NF-kappa B-inducing kinase signaling pathway. J. Biol. Chem. 283:23169-23178. http://dx.doi.org/10.1074/jbc.M802729200.
    • (2008) J. Biol. Chem. , vol.283 , pp. 23169-23178
    • Liu, P.1    Li, K.2    Garofalo, R.P.3    Brasier, A.R.4
  • 58
    • 0032516520 scopus 로고    scopus 로고
    • NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation
    • Uhlik M, Good L, Xiao G, Harhaj EW, Zandi E, Karin M, Sun SC. 1998.NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation. J. Biol. Chem. 273:21132-21136. http://dx.doi.org/10.1074/jbc.273.33.21132.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21132-21136
    • Uhlik, M.1    Good, L.2    Xiao, G.3    Harhaj, E.W.4    Zandi, E.5    Karin, M.6    Sun, S.C.7
  • 59
    • 54149086493 scopus 로고    scopus 로고
    • HIV-1 Tat protein induces IL-10 production in monocytes by classical and alternative NF-kappaB pathways
    • Leghmari K, Bennasser Y, Bahraoui E. 2008. HIV-1 Tat protein induces IL-10 production in monocytes by classical and alternative NF-kappaB pathways. Eur. J. Cell Biol. 87:947-962. http://dx.doi.org/10.1016/j.ejcb.2008.06.005.
    • (2008) Eur. J. Cell Biol. , vol.87 , pp. 947-962
    • Leghmari, K.1    Bennasser, Y.2    Bahraoui, E.3
  • 61
    • 34548364068 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation
    • Matta H, Mazzacurati L, Schamus S, Yang T, Sun Q, Chaudhary PM. 2007. Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation. J. Biol. Chem. 282: 24858-24865. http://dx.doi.org/10.1074/jbc.M700118200.
    • (2007) J. Biol. Chem. , vol.282 , pp. 24858-24865
    • Matta, H.1    Mazzacurati, L.2    Schamus, S.3    Yang, T.4    Sun, Q.5    Chaudhary, P.M.6
  • 62
    • 80053940482 scopus 로고    scopus 로고
    • Deletion of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein, vFLIP, from the viral genome compromises the activation of STAT1-responsive cellular genes and spindle cell formation in endothelial cells
    • Alkharsah KR, Singh VV, Bosco R, Santag S, Grundhoff A, Konrad A, Sturzl M, Wirth D, Dittrich-Breiholz O, Kracht M, Schulz TF. 2011. Deletion of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein, vFLIP, from the viral genome compromises the activation of STAT1-responsive cellular genes and spindle cell formation in endothelial cells. J. Virol. 85:10375-10388. http://dx.doi.org/10.1128/JVI.00226-11.
    • (2011) J. Virol. , vol.85 , pp. 10375-10388
    • Alkharsah, K.R.1    Singh, V.V.2    Bosco, R.3    Santag, S.4    Grundhoff, A.5    Konrad, A.6    Sturzl, M.7    Wirth, D.8    Dittrich-Breiholz, O.9    Kracht, M.10    Schulz, T.F.11
  • 63
    • 0032823313 scopus 로고    scopus 로고
    • Induction of interleukin-8 synthesis integrates effects on transcription andmRNAdegradation from at least three different cytokine-or stress-activated signal transduction pathways
    • Holtmann H, Winzen R, Holland P, Eickemeier S, Hoffmann E, Wallach D, Malinin NL, Cooper JA, Resch K, Kracht M. 1999. Induction of interleukin-8 synthesis integrates effects on transcription andmRNAdegradation from at least three different cytokine-or stress-activated signal transduction pathways. Mol. Cell. Biol. 19:6742-6753.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6742-6753
    • Holtmann, H.1    Winzen, R.2    Holland, P.3    Eickemeier, S.4    Hoffmann, E.5    Wallach, D.6    Malinin, N.L.7    Cooper, J.A.8    Resch, K.9    Kracht, M.10
  • 64
    • 0028853402 scopus 로고
    • The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NFkappa B and cell surface phenotype via two effector regions in its carboxyterminal cytoplasmic domain
    • Huen DS, Henderson SA, Croom-Carter D, Rowe M. 1995. The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NFkappa B and cell surface phenotype via two effector regions in its carboxyterminal cytoplasmic domain. Oncogene 10:549-560.
    • (1995) Oncogene , vol.10 , pp. 549-560
    • Huen, D.S.1    Henderson, S.A.2    Croom-Carter, D.3    Rowe, M.4
  • 65
    • 0030747497 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-kappaB pathway involving TNF receptor-associated factors
    • Eliopoulos AG, Stack M, Dawson CW, Kaye KM, Hodgkin L, Sihota S, Rowe M, Young LS. 1997. Epstein-Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-kappaB pathway involving TNF receptor-associated factors. Oncogene 14:2899-2916. http://dx.doi.org/10.1038/sj.onc.1201258.
    • (1997) Oncogene , vol.14 , pp. 2899-2916
    • Eliopoulos, A.G.1    Stack, M.2    Dawson, C.W.3    Kaye, K.M.4    Hodgkin, L.5    Sihota, S.6    Rowe, M.7    Young, L.S.8
  • 67
    • 77952773419 scopus 로고    scopus 로고
    • Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor
    • Sanjo H, Zajonc DM, Braden R, Norris PS, Ware CF. 2010. Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor. J. Biol. Chem. 285:17148-17155. http://dx.doi.org/10.1074/jbc.M110.105874.
    • (2010) J. Biol. Chem. , vol.285 , pp. 17148-17155
    • Sanjo, H.1    Zajonc, D.M.2    Braden, R.3    Norris, P.S.4    Ware, C.F.5
  • 68
    • 5644302162 scopus 로고    scopus 로고
    • Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase
    • Ramakrishnan P, Wang W, Wallach D. 2004. Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity 21:477-489. http://dx.doi.org/10.1016/j.immuni.2004.08.009.
    • (2004) Immunity , vol.21 , pp. 477-489
    • Ramakrishnan, P.1    Wang, W.2    Wallach, D.3
  • 69
    • 33750433585 scopus 로고    scopus 로고
    • Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses
    • Hiscott J, Nguyen TL, Arguello M, Nakhaei P, Paz S. 2006. Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses. Oncogene 25:6844-6867. http://dx.doi.org/10.1038/sj.onc.1209941.
    • (2006) Oncogene , vol.25 , pp. 6844-6867
    • Hiscott, J.1    Nguyen, T.L.2    Arguello, M.3    Nakhaei, P.4    Paz, S.5
  • 70
    • 0035809310 scopus 로고    scopus 로고
    • Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I
    • Matsushima A, Kaisho T, Rennert PD, Nakano H, Kurosawa K, Uchida D, Takeda K, Akira S, Matsumoto M. 2001. Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I. J. Exp. Med. 193:631-636. http://dx.doi.org/10.1084/jem.193.5.631.
    • (2001) J. Exp. Med. , vol.193 , pp. 631-636
    • Matsushima, A.1    Kaisho, T.2    Rennert, P.D.3    Nakano, H.4    Kurosawa, K.5    Uchida, D.6    Takeda, K.7    Akira, S.8    Matsumoto, M.9
  • 71
    • 19944411839 scopus 로고    scopus 로고
    • Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta
    • Joo M, Hahn YS, Kwon M, Sadikot RT, Blackwell TS, Christman JW. 2005. Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta. J. Virol. 79:7648-7657. http://dx.doi.org/10.1128/JVI.79.12.7648-7657.2005.
    • (2005) J. Virol. , vol.79 , pp. 7648-7657
    • Joo, M.1    Hahn, Y.S.2    Kwon, M.3    Sadikot, R.T.4    Blackwell, T.S.5    Christman, J.W.6
  • 72
    • 0347719385 scopus 로고    scopus 로고
    • Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation
    • Luftig M, Yasui T, Soni V, Kang MS, Jacobson N, Cahir-McFarland E, Seed B, Kieff E. 2004. Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation. Proc. Natl. Acad. Sci. U. S. A. 101:141-146. http://dx.doi.org/10.1073/pnas.2237183100.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 141-146
    • Luftig, M.1    Yasui, T.2    Soni, V.3    Kang, M.S.4    Jacobson, N.5    Cahir-McFarland, E.6    Seed, B.7    Kieff, E.8
  • 74
    • 0032589261 scopus 로고    scopus 로고
    • IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1
    • Chu ZL, Shin YA, Yang JM, DiDonato JA, Ballard DW. 1999. IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1. J. Biol. Chem. 274:15297-15300. http://dx.doi.org/10.1074/jbc.274.22.15297.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15297-15300
    • Chu, Z.L.1    Shin, Y.A.2    Yang, J.M.3    DiDonato, J.A.4    Ballard, D.W.5
  • 76
    • 0033551607 scopus 로고    scopus 로고
    • IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein
    • Harhaj EW, Sun SC. 1999. IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein. J. Biol. Chem. 274:22911-22914. http://dx.doi.org/10.1074/jbc.274.33.22911.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22911-22914
    • Harhaj, E.W.1    Sun, S.C.2
  • 77
    • 0033580931 scopus 로고    scopus 로고
    • Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma
    • Jin DY, Giordano V, Kibler KV, Nakano H, Jeang KT. 1999. Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma. J. Biol. Chem. 274:17402-17405.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17402-17405
    • Jin, D.Y.1    Giordano, V.2    Kibler, K.V.3    Nakano, H.4    Jeang, K.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.